CN109641013B - 包含凝血酶处理干细胞来源的外泌体的皮肤创伤的治疗用组合物 - Google Patents

包含凝血酶处理干细胞来源的外泌体的皮肤创伤的治疗用组合物 Download PDF

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CN109641013B
CN109641013B CN201780047575.0A CN201780047575A CN109641013B CN 109641013 B CN109641013 B CN 109641013B CN 201780047575 A CN201780047575 A CN 201780047575A CN 109641013 B CN109641013 B CN 109641013B
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exosomes
derived
thrombin
use according
growth factor
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CN109641013A (zh
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张允实
朴元淳
成东庆
安沼玧
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Samsung Life Public Welfare Foundation
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CN201780047575.0A 2016-07-01 2017-06-27 包含凝血酶处理干细胞来源的外泌体的皮肤创伤的治疗用组合物 Active CN109641013B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20160083703 2016-07-01
KR10-2016-0083703 2016-07-01
KR1020170080366A KR101860266B1 (ko) 2016-07-01 2017-06-26 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물
KR10-2017-0080366 2017-06-26
PCT/KR2017/006776 WO2018004237A1 (ko) 2016-07-01 2017-06-27 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물

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CN109641013A CN109641013A (zh) 2019-04-16
CN109641013B true CN109641013B (zh) 2022-07-26

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US (1) US12239695B2 (enExample)
EP (1) EP3479831B1 (enExample)
JP (1) JP6826135B2 (enExample)
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CN (1) CN109641013B (enExample)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
KR101973284B1 (ko) 2017-01-16 2019-04-29 사회복지법인 삼성생명공익재단 신생아 ｈｉｅ 치료용 조성물
KR102278102B1 (ko) 2018-07-27 2021-07-15 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간질환의 예방 또는 치료용 조성물
WO2020022541A1 (ko) 2018-07-27 2020-01-30 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간부전의 예방 또는 치료용 조성물
KR102323056B1 (ko) * 2019-05-02 2021-11-09 에스씨엠생명과학 주식회사 hPL 함유 배지에서 배양된 중간엽 줄기세포의 배양액을 포함하는 화장료 조성물
KR102159394B1 (ko) * 2019-10-04 2020-09-24 (주)에스디생명공학 바다제비집에서 유래된 엑소좀을 유효성분으로 포함하는 피부 상태 개선용 조성물
US12491212B2 (en) 2019-11-12 2025-12-09 Brexogen Inc. Composition for preventing or treating renal diseases, comprising exosomes derived from precursor cells of induced pluripotent stem cell-derived mesenchymal stem cells
JP2021116228A (ja) * 2020-01-22 2021-08-10 医薬資源研究所株式会社 抗酸化ストレス剤、化粧品、および医薬品
US12077780B2 (en) 2020-02-14 2024-09-03 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof
KR20210127510A (ko) * 2020-04-14 2021-10-22 사회복지법인 삼성생명공익재단 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 당뇨병성 피부질환 예방 또는 치료용 조성물
CN111888379A (zh) * 2020-08-17 2020-11-06 济宁医学院附属医院 干细胞来源的微囊泡在制备修复瘢痕的制剂中的应用
EP4252761A4 (en) * 2020-11-26 2024-06-05 Samsung Life Public Welfare Foundation COMPOSITION FOR THE TREATMENT OF INFECTIOUS DISEASES, COMPRISING EXOSOMES DERIVED FROM THROMBIN-PROCESSED STEM CELLS
CN114904043B (zh) * 2022-04-28 2023-07-21 深圳市儿童医院 复合水凝胶及其制备方法和应用
JP2025539861A (ja) * 2022-11-25 2025-12-09 エルピス・セル・セラピューティクス ｖＭＳＣのセクレトームおよびその用途

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JP5911874B2 (ja) * 2010-10-18 2016-04-27 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 発毛を促進又は増強するためのエキソソームの使用
US20150125950A1 (en) 2012-05-18 2015-05-07 Agency For Science, Technology And Research (A*Sta (A*Star) Umbilical cord mesenchymal stem cell exosomes
KR20140066456A (ko) 2012-11-23 2014-06-02 호서대학교 산학협력단 피부각질세포 유래 엑소좀, 엑소좀을 포함하는 분획물의 피부재생용 화장품 조성물 및 이의 용도
GB201317889D0 (en) * 2013-10-09 2013-11-20 Reneuron Ltd Product and use
JP6343671B2 (ja) * 2013-12-12 2018-06-13 サムスン ライフ パブリック ウェルフェア ファウンデーション トロンビンを利用した幹細胞由来のエキソソームの生成促進方法
US9919011B2 (en) * 2014-03-18 2018-03-20 Samsung Life Public Welfare Foundation Method for treating an inflammatory brain disease comprising administering a stem cell-derived exosome
CN105477016A (zh) * 2015-11-13 2016-04-13 中国人民解放军第二军医大学 人间充质干细胞来源的外泌体在抗组织纤维化及瘢痕形成中的应用

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EP3479831A1 (en) 2019-05-08
JP2019520365A (ja) 2019-07-18
KR101860266B1 (ko) 2018-05-24
EP3479831A4 (en) 2020-03-25
KR20180003999A (ko) 2018-01-10
CN109641013A (zh) 2019-04-16
JP6826135B2 (ja) 2021-02-03
US20190314469A1 (en) 2019-10-17
US12239695B2 (en) 2025-03-04
EP3479831B1 (en) 2022-06-15

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