KR101854879B1 - 염증성 질환의 치료에 사용하기 위한 n-아실에탄올아민에 특이적인 아미다제의 조절용 조성물 및 조절 방법 - Google Patents

염증성 질환의 치료에 사용하기 위한 n-아실에탄올아민에 특이적인 아미다제의 조절용 조성물 및 조절 방법 Download PDF

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KR101854879B1
KR101854879B1 KR1020147025782A KR20147025782A KR101854879B1 KR 101854879 B1 KR101854879 B1 KR 101854879B1 KR 1020147025782 A KR1020147025782 A KR 1020147025782A KR 20147025782 A KR20147025782 A KR 20147025782A KR 101854879 B1 KR101854879 B1 KR 101854879B1
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inflammatory
chronic
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KR20140147819A (ko
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발레 프란체스코 델라
발레 마리아 페데리카 델라
가브리엘레 마르콜론고
마르초 빈첸초 디
살바토레 쿠초크레아
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에피테크 그룹 에스.알.엘.
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    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/12—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals containing only hydrogen and carbon atoms
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    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
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    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
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    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020147025782A 2012-02-17 2012-02-17 염증성 질환의 치료에 사용하기 위한 n-아실에탄올아민에 특이적인 아미다제의 조절용 조성물 및 조절 방법 Active KR101854879B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2012/000050 WO2013121449A1 (en) 2012-02-17 2012-02-17 Compositions and methods for the modulation of specific amidases for n-acylethanolamines for use in the therapy of inflammatory diseases

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KR101854879B1 true KR101854879B1 (ko) 2018-05-04

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US (1) US9512091B2 (enExample)
EP (1) EP2814489B1 (enExample)
JP (1) JP5982016B2 (enExample)
KR (1) KR101854879B1 (enExample)
CN (1) CN104244948B (enExample)
AR (1) AR090066A1 (enExample)
AU (1) AU2012327209B2 (enExample)
BR (1) BR112014020992B1 (enExample)
CA (1) CA2864259C (enExample)
DK (1) DK2814489T3 (enExample)
ES (1) ES2648188T3 (enExample)
IN (1) IN2014DN06850A (enExample)
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EP2921171B1 (en) * 2014-03-21 2019-10-16 EPITECH GROUP S.p.A. Ophthalmic, intra-articular or intravesical preparations containing N-acyl-ethanolamines
US20160008301A1 (en) * 2014-07-08 2016-01-14 Epitech Group S.R.L. Use of Adelmidrol in the Treatment of Epithelial Dysfunctions
JP2018517775A (ja) * 2015-06-16 2018-07-05 マードック チルドレンズ リサーチ インスティチュート クローン病を治療する方法
WO2017025588A1 (en) * 2015-08-11 2017-02-16 Eyesiu Medicines B.V. Pegylated lipid nanoparticle with bioactive lipophilic compound
EP3520785B1 (en) * 2016-10-09 2024-07-17 Shenzhen Eulikan Biotechnology Co., Ltd. Uses of bacteriostatic agent formula in preparing composition for vaginal use and composition for vaginal use
US10143639B2 (en) * 2017-03-22 2018-12-04 William Robert McDaniel Use of adelmidrol and other topical or oral cannabinomimetic or aliamide mast cell inhibitors to treat dermatoheliosis, seborrheic keratoses, and androgenetic alopecia
SG10201802129QA (en) * 2017-07-05 2019-02-27 Frimline Private Ltd A pharmaceutical composition for neuropathic pain
PH12018000227B1 (en) * 2017-09-05 2019-03-11 Frimline Private Ltd A pharmaceutical composition for improving or preventing progression of chronic kidney disease
EP3574899A1 (en) 2018-05-28 2019-12-04 Université de Bourgogne Oleic acid derivatives, pharmaceutical composition or food composition comprising said oleic acid derivatives, and their uses
FR3098394B1 (fr) * 2019-07-12 2022-07-08 Expanscience Lab Composition comprenant au moins une oxazoline pour inhiber la croissance de levure du genre Malassezia impliquée notamment dans les croûtes de lait
IT202200017820A1 (it) * 2022-08-30 2024-03-01 Unifarco S P A Compressa nutraceutica comprendente palmitoiletanolamide
CN118125936B (zh) * 2022-11-25 2025-10-03 南京清普生物科技有限公司 N-酰基乙醇酰胺衍生物及其制备方法和应用
EP4751720A1 (en) * 2024-11-27 2026-06-03 EPITECH GROUP S.p.A. 2-pentadecyl-2-oxazoline in association with butyric acid or a salt thereof in the treatment of epilepsy

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