KR101650956B1 - Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄 - Google Patents

Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄 Download PDF

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KR101650956B1
KR101650956B1 KR1020107002558A KR20107002558A KR101650956B1 KR 101650956 B1 KR101650956 B1 KR 101650956B1 KR 1020107002558 A KR1020107002558 A KR 1020107002558A KR 20107002558 A KR20107002558 A KR 20107002558A KR 101650956 B1 KR101650956 B1 KR 101650956B1
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pyrimidin
cyclopenta
piperazin
dihydro
methyl
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Expired - Fee Related
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Korean (ko)
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KR20100044819A (ko
Inventor
조세프 벵시크
제임스 에프. 블레이크
제임스 엠. 그레이엄
마틴 에프. 헨트먼
니콜라스 씨. 캘런
이언 에스. 미첼
스티븐 티. 슐락터
키스 엘. 스펜서
뎅밍 샤오
루이 수
마이크 웰치
준 리앙
브라이언 에스. 사피나
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어레이 바이오파마 인크.
제넨테크, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
KR1020107002558A 2007-07-05 2008-07-03 Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄 Expired - Fee Related KR101650956B1 (ko)

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US94813807P 2007-07-05 2007-07-05
US60/948,138 2007-07-05
US2008808P 2008-01-09 2008-01-09
US61/020,088 2008-01-09

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KR1020157020046A Division KR20150089099A (ko) 2007-07-05 2008-07-03 Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄

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KR20100044819A KR20100044819A (ko) 2010-04-30
KR101650956B1 true KR101650956B1 (ko) 2016-08-24

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KR1020157020046A Ceased KR20150089099A (ko) 2007-07-05 2008-07-03 Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄

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US (1) US8618097B2 (enExample)
EP (1) EP2170863B1 (enExample)
JP (2) JP5628028B2 (enExample)
KR (2) KR101650956B1 (enExample)
CN (2) CN103396409B (enExample)
AR (1) AR067413A1 (enExample)
AU (1) AU2008272830B8 (enExample)
BR (1) BRPI0813999A2 (enExample)
CA (1) CA2692502C (enExample)
CO (1) CO6251283A2 (enExample)
CR (1) CR11229A (enExample)
EC (1) ECSP109937A (enExample)
ES (1) ES2551352T3 (enExample)
MA (1) MA31679B1 (enExample)
NZ (1) NZ582692A (enExample)
RU (1) RU2486181C2 (enExample)
SG (1) SG185274A1 (enExample)
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