KR101621726B1 - 유스타키오관 기능장애 치료용 국소 약학적 조성물 - Google Patents

유스타키오관 기능장애 치료용 국소 약학적 조성물 Download PDF

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Publication number
KR101621726B1
KR101621726B1 KR1020107029075A KR20107029075A KR101621726B1 KR 101621726 B1 KR101621726 B1 KR 101621726B1 KR 1020107029075 A KR1020107029075 A KR 1020107029075A KR 20107029075 A KR20107029075 A KR 20107029075A KR 101621726 B1 KR101621726 B1 KR 101621726B1
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South Korea
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pharmaceutical composition
topical pharmaceutical
eustachian tube
composition according
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Expired - Fee Related
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Korean (ko)
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KR20110022624A (ko
Inventor
콜린 러셀 앤더슨
버크하드 프란츠
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더 유니버시티 오브 멜버른
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Priority claimed from AU2008902659A external-priority patent/AU2008902659A0/en
Application filed by 더 유니버시티 오브 멜버른 filed Critical 더 유니버시티 오브 멜버른
Publication of KR20110022624A publication Critical patent/KR20110022624A/ko
Application granted granted Critical
Publication of KR101621726B1 publication Critical patent/KR101621726B1/ko
Assigned to 오티펙스 테라퓨틱스 피티와이 엘티디 reassignment 오티펙스 테라퓨틱스 피티와이 엘티디 권리의 전부이전등록 Assignors: 더 유니버시티 오브 멜버른
Assigned to 오토라눔 아게 reassignment 오토라눔 아게 권리의 전부이전등록 Assignors: 오티펙스 테라퓨틱스 피티와이 엘티디
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020107029075A 2008-05-27 2009-05-27 유스타키오관 기능장애 치료용 국소 약학적 조성물 Expired - Fee Related KR101621726B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2008902659A AU2008902659A0 (en) 2008-05-27 Method of Treatment
AU2008902659 2008-05-27

Publications (2)

Publication Number Publication Date
KR20110022624A KR20110022624A (ko) 2011-03-07
KR101621726B1 true KR101621726B1 (ko) 2016-05-17

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KR1020107029075A Expired - Fee Related KR101621726B1 (ko) 2008-05-27 2009-05-27 유스타키오관 기능장애 치료용 국소 약학적 조성물

Country Status (14)

Country Link
US (1) US8642631B2 (https=)
EP (1) EP2293794B1 (https=)
JP (1) JP5543963B2 (https=)
KR (1) KR101621726B1 (https=)
CN (1) CN102046170B (https=)
AU (1) AU2009253739B2 (https=)
BR (1) BRPI0912126A2 (https=)
CA (1) CA2765190C (https=)
DK (1) DK2293794T3 (https=)
EA (1) EA022565B1 (https=)
ES (1) ES2419204T3 (https=)
NZ (1) NZ589742A (https=)
PT (1) PT2293794E (https=)
WO (1) WO2009143572A1 (https=)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10105592A1 (de) 2001-02-06 2002-08-08 Achim Goepferich Platzhalter zur Arzneistofffreigabe in der Stirnhöhle
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US8435285B2 (en) * 2003-11-25 2013-05-07 Boston Scientific Scimed, Inc. Composite stent with inner and outer stent elements and method of using the same
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US20070208252A1 (en) * 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US20060004323A1 (en) 2004-04-21 2006-01-05 Exploramed Nc1, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US7559925B2 (en) 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20070167682A1 (en) * 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US7816975B2 (en) * 2005-09-20 2010-10-19 Hewlett-Packard Development Company, L.P. Circuit and method for bias voltage generation
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
WO2008124787A2 (en) 2007-04-09 2008-10-16 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US10206821B2 (en) 2007-12-20 2019-02-19 Acclarent, Inc. Eustachian tube dilation balloon with ventilation path
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
KR101653180B1 (ko) 2008-07-30 2016-09-01 아클라런트, 인코포레이션 부비 개구 탐지기 장치 및 방법
RU2506056C2 (ru) 2008-09-18 2014-02-10 Аккларент, Инк. Способы и аппарат для лечения заболеваний уха, горла, носа
US20100241155A1 (en) 2009-03-20 2010-09-23 Acclarent, Inc. Guide system with suction
US7978742B1 (en) 2010-03-24 2011-07-12 Corning Incorporated Methods for operating diode lasers
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
JP7080828B2 (ja) 2016-05-27 2022-06-06 ライフ テクノロジーズ コーポレーション 生物学的データに対するグラフィカルユーザインターフェースのための方法およびシステム
ES2969301T3 (es) * 2017-02-02 2024-05-17 Otolanum Ag Composición intranasal que comprende betahistina
WO2018170532A1 (en) * 2017-03-22 2018-09-27 Franz, Lilian Ann Treatment method
AU2019208152B2 (en) * 2017-03-22 2021-07-01 Burkhard Karl-Heinz Gunther Franz Treatment method
FI3600276T3 (fi) 2017-03-28 2023-06-29 Intrabio Ltd Betahistiini tai sen farmaseuttisesti hyväksyttävä suola ja monoamiinioksidaasin inhibiittori käytettäväksi yhden tai useamman huimausoireen hoitamisessa tai ehkäisemisessä kohteessa

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094240A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of physiologically active compounds through an inhalation route
US20030017114A1 (en) 2001-05-24 2003-01-23 Rabinowitz Joshua D. Delivery of physiologically active compounds through an inhalation route

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3149034A (en) 1961-07-17 1964-09-15 Umimed Inc Method of relieving pain with (pyridyllower alkyl)-amines
US3632765A (en) 1969-07-18 1972-01-04 Unimed Inc Treatment of shock
GB1241906A (en) * 1969-11-01 1971-08-04 Unimed Inc Salts of beta-(pyridyl alkyl) amines with 21-hydroxy steroid polybasic acid esters
JPS5938202B2 (ja) 1976-03-05 1984-09-14 エーザイ株式会社 難聴治療剤
GB1577871A (en) 1976-05-28 1980-10-29 Unimed Inc Prevention of myocardial infarction
FR2397840B1 (https=) * 1977-07-22 1981-03-20 Cherqui Jean
FR2432313A1 (fr) 1978-08-01 1980-02-29 Foulhoux Pierre Nouvelle forme galenique de la betahistine et son procede d'obtention
JPS55154915A (en) * 1979-05-21 1980-12-02 Jiyan Sadeia Shieruki Medicine mold
DE3634016A1 (de) 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
IT1229237B (it) 1989-05-08 1991-07-26 Prodotti Formenti Sali di (2-(piridil)etil) metilammina
GB9104854D0 (en) 1991-03-07 1991-04-17 Reckitt & Colmann Prod Ltd Sustained release compositions
JPH06219947A (ja) 1993-01-26 1994-08-09 Kinki Univ 経皮投与製剤
GB2280604B (en) 1993-07-02 1997-04-30 Resource Medical Limited Processing of active agents
IT1309591B1 (it) 1999-03-05 2002-01-24 Formenti Farmaceutici Spa Composizioni a rilascio controllato di betaistina.
JP2001064205A (ja) 1999-06-25 2001-03-13 Dai Ichi Seiyaku Co Ltd 製剤組成物
US6156294A (en) * 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US20020106408A1 (en) 2000-12-01 2002-08-08 Johnatan Bacon Prolamin-based sustained-release compositions and delayed-onset compositions
AU2002240359A1 (en) 2001-02-14 2002-08-28 Sarfaraz K. Niazi Pharmaceutical composition for the treatment of alopecia
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
WO2003026631A1 (en) 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
WO2004089313A2 (en) 2003-04-01 2004-10-21 Transform Pharmaceuticals, Inc. Novel olanzapine forms and related methods of treatment
WO2003077902A1 (en) 2002-02-19 2003-09-25 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
EP1511490A4 (en) 2002-05-31 2009-03-11 Transform Pharmaceuticals Inc NOVEL CONAZOLE CRYSTALLINE FORMS AND RELATED METHODS, PHARMACEUTICAL COMPOSITIONS AND METHODS
GB0213869D0 (en) 2002-06-17 2002-07-31 Arakis Ltd The treatment of pain
AU2003281158A1 (en) * 2002-07-12 2004-02-02 Arakis Ltd. The treatment of emesis
UA84277C2 (ru) 2002-10-25 2008-10-10 Лабофарм Инк. Композиция трамадола с пролонгированным высвобождением с 24-часовым действием
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
MXPA05004410A (es) 2002-10-25 2005-11-23 Labopharm Inc Composiciones de liberacion controlada.
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
DE60320965D1 (de) 2003-07-04 2008-06-26 Formenti Farmaceutici Spa Betahistinezubereitungen mit kontrollierter Freisetzung
WO2005011665A1 (en) * 2003-07-22 2005-02-10 Arakis Ltd. The use of proglumide for the treatment of emesis
BRPI0506807A (pt) 2004-04-22 2007-05-29 Mor Research Applic Ltd método de gerenciamento de consumo de alimento e composição farmacológica
CN1568986A (zh) 2004-05-13 2005-01-26 南昌弘益科技有限公司 盐酸倍他司汀滴丸及其制备方法
GB0506800D0 (en) 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
CA2605341A1 (en) 2005-05-09 2006-11-16 Drugtech Corporation Modified-release pharmaceutical compositions
US20070009564A1 (en) 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
WO2007011707A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
CN1732934B (zh) 2005-08-10 2011-10-05 陈学峰 注射用盐酸倍他司汀冻干粉针剂及其制备方法
US8158152B2 (en) 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
US8119668B2 (en) 2005-12-23 2012-02-21 Nelson Erik B Treatment methods employing histamine H3 receptor antagonists, including betahistine
US7951845B2 (en) 2006-01-19 2011-05-31 The Regents Of The University Of Michigan Composition and method of treating hearing loss
US20070231390A1 (en) 2006-03-29 2007-10-04 Andrx Labs, Llc Formulations including hygroscopic compounds
RU2308941C1 (ru) 2006-05-10 2007-10-27 Открытое акционерное общество "Московское производственное химико-фармацевтическое объединение им. Н.А. Семашко" Твердая лекарственная форма, обладающая гистаминоподобным действием, и способ ее получения
US20080066739A1 (en) 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
CN101668544B (zh) * 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
AU2008214380A1 (en) 2007-02-02 2008-08-14 Colucid Pharmaceuticals, Inc. Compounds that inhibit cholinesterase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094240A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of physiologically active compounds through an inhalation route
US20030017114A1 (en) 2001-05-24 2003-01-23 Rabinowitz Joshua D. Delivery of physiologically active compounds through an inhalation route

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Acta oto-laryngologica. Vol.128(5), pp.520-524*

Also Published As

Publication number Publication date
JP5543963B2 (ja) 2014-07-09
ES2419204T3 (es) 2013-08-19
BRPI0912126A2 (pt) 2015-11-03
NZ589742A (en) 2012-06-29
WO2009143572A1 (en) 2009-12-03
US8642631B2 (en) 2014-02-04
EA201071361A1 (ru) 2011-06-30
AU2009253739A1 (en) 2009-12-03
US20110166190A1 (en) 2011-07-07
CN102046170B (zh) 2012-11-28
DK2293794T3 (da) 2013-08-19
HK1155387A1 (en) 2012-05-18
CA2765190C (en) 2016-07-19
EP2293794B1 (en) 2013-05-22
EP2293794A4 (en) 2011-06-22
CN102046170A (zh) 2011-05-04
CA2765190A1 (en) 2009-12-03
EP2293794A1 (en) 2011-03-16
PT2293794E (pt) 2013-07-10
AU2009253739B2 (en) 2014-02-06
JP2011520992A (ja) 2011-07-21
KR20110022624A (ko) 2011-03-07
EA022565B1 (ru) 2016-01-29

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