KR101616139B1 - 관류 영상화를 포함하는 용도를 위한 조영제 - Google Patents
관류 영상화를 포함하는 용도를 위한 조영제 Download PDFInfo
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- KR101616139B1 KR101616139B1 KR1020107021556A KR20107021556A KR101616139B1 KR 101616139 B1 KR101616139 B1 KR 101616139B1 KR 1020107021556 A KR1020107021556 A KR 1020107021556A KR 20107021556 A KR20107021556 A KR 20107021556A KR 101616139 B1 KR101616139 B1 KR 101616139B1
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- 0 **(*=C(*)C(I)=C1*)C1=O Chemical compound **(*=C(*)C(I)=C1*)C1=O 0.000 description 6
- XTNLABPPRDUGLZ-UHFFFAOYSA-N CC(C)(C)N(C1=O)N=CC(OCc2ccc(COCCO)cc2)=C1Cl Chemical compound CC(C)(C)N(C1=O)N=CC(OCc2ccc(COCCO)cc2)=C1Cl XTNLABPPRDUGLZ-UHFFFAOYSA-N 0.000 description 1
- JIKXXWBJUGPPIS-UHFFFAOYSA-N CCC(CO)Oc1ccc(COC(C=NN(C(C)(C)C)C2=O)=C2Cl)cc1 Chemical compound CCC(CO)Oc1ccc(COC(C=NN(C(C)(C)C)C2=O)=C2Cl)cc1 JIKXXWBJUGPPIS-UHFFFAOYSA-N 0.000 description 1
- LYWZMGGXPMJKFV-UHFFFAOYSA-N COC(CCC(c1ccc(CCO)cc1)=O)=O Chemical compound COC(CCC(c1ccc(CCO)cc1)=O)=O LYWZMGGXPMJKFV-UHFFFAOYSA-N 0.000 description 1
- ZOYIIFMKPTYKKM-UHFFFAOYSA-N COC(CCCc1ccc(CCO)cc1)=O Chemical compound COC(CCCc1ccc(CCO)cc1)=O ZOYIIFMKPTYKKM-UHFFFAOYSA-N 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6759308P | 2008-02-29 | 2008-02-29 | |
| US61/067,593 | 2008-02-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20100121530A KR20100121530A (ko) | 2010-11-17 |
| KR101616139B1 true KR101616139B1 (ko) | 2016-04-27 |
Family
ID=41016660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020107021556A Active KR101616139B1 (ko) | 2008-02-29 | 2009-02-27 | 관류 영상화를 포함하는 용도를 위한 조영제 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9408927B2 (https=) |
| EP (1) | EP2257315B1 (https=) |
| JP (3) | JP5946992B2 (https=) |
| KR (1) | KR101616139B1 (https=) |
| CN (1) | CN102014969B (https=) |
| AU (1) | AU2009220244B2 (https=) |
| CA (2) | CA2716354C (https=) |
| DK (1) | DK2257315T3 (https=) |
| ES (1) | ES2767973T3 (https=) |
| IL (1) | IL207853A (https=) |
| PT (1) | PT2257315T (https=) |
| WO (2) | WO2009110984A2 (https=) |
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| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| US7485283B2 (en) * | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
| AU2009220244B2 (en) | 2008-02-29 | 2014-10-09 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including perfusion imaging |
| US20100241001A1 (en) * | 2009-03-20 | 2010-09-23 | Palmeri Mark L | Ultrasound Methods, Systems and Computer Program Products for Imaging Fluids |
| KR101602992B1 (ko) * | 2009-04-15 | 2016-03-11 | 랜티우스 메디컬 이메징, 인크. | 아스코르브산을 사용한 방사성 약제 조성물의 안정화 |
| CN102858752B (zh) * | 2010-02-08 | 2018-10-16 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
| EP2753605B1 (en) | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| WO2013058774A1 (en) * | 2011-10-21 | 2013-04-25 | Lantheus Medical Imaging, Inc. | Compositions comprising ascorbic acid and an imaging agent and related methods |
| CN103254140B (zh) * | 2012-02-17 | 2016-02-17 | 北京师范大学 | 新型18f标记取代喹唑啉类化合物及其制备方法和肿瘤pet显像应用 |
| WO2013173004A2 (en) | 2012-04-10 | 2013-11-21 | Lantheus Medical Imaging, Inc. | Radiopharmaceutical synthesis methods |
| AU2013203000B9 (en) * | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| EP2882863B1 (en) * | 2012-08-13 | 2021-07-14 | The General Hospital Corporation | System and method for quantitative mapping of mitocondrial complex 1 |
| CN104583192B (zh) * | 2012-08-24 | 2016-10-12 | 浜松光子学株式会社 | 适合于线粒体复合体-1检出的化合物 |
| EP4296364B1 (en) | 2013-12-03 | 2025-12-03 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
| WO2017139653A1 (en) * | 2016-02-10 | 2017-08-17 | The Charles Stark Draper Laboratory, Inc. | Systems and methods for imaging |
| GB201805253D0 (en) | 2018-03-29 | 2018-05-16 | Ge Healthcare Ltd Ip | Solid phase extraction |
| CN110305010B (zh) * | 2019-07-17 | 2022-05-13 | 江苏中旗科技股份有限公司 | 一种2,5-二甲基苯乙酸的制备方法 |
| GB201915206D0 (en) | 2019-10-21 | 2019-12-04 | Ge Healthcare Ltd | Use of cyclodextrins as a radiostabilizer |
| JP2024517682A (ja) * | 2021-04-23 | 2024-04-23 | アルテミス インコーポレイテッド | 陽子エネルギーデグレーダデバイス及びその使用方法 |
| JPWO2023013757A1 (https=) * | 2021-08-05 | 2023-02-09 | ||
| WO2024132895A1 (en) * | 2022-12-19 | 2024-06-27 | Syngenta Crop Protection Ag | Microbiocidal dihydrooxadiazinyl pyridazinone compounds |
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| US20160361448A1 (en) | 2016-12-15 |
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| AU2009220244A1 (en) | 2009-09-11 |
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| WO2009108376A2 (en) | 2009-09-03 |
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| WO2009110984A3 (en) | 2009-12-10 |
| JP5922207B2 (ja) | 2016-05-24 |
| CA2967254C (en) | 2019-03-26 |
| US20180133347A9 (en) | 2018-05-17 |
| US20110091374A1 (en) | 2011-04-21 |
| EP2257315B1 (en) | 2019-10-23 |
| CA2967254A1 (en) | 2009-09-11 |
| CA2716354C (en) | 2017-06-13 |
| AU2009220244B2 (en) | 2014-10-09 |
| JP5946992B2 (ja) | 2016-07-06 |
| IL207853A (en) | 2015-05-31 |
| US9408927B2 (en) | 2016-08-09 |
| CN102014969A (zh) | 2011-04-13 |
| IL207853A0 (en) | 2010-12-30 |
| ES2767973T3 (es) | 2020-06-19 |
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