KR101539761B1 - 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법 - Google Patents

물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법 Download PDF

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KR101539761B1
KR101539761B1 KR1020130011722A KR20130011722A KR101539761B1 KR 101539761 B1 KR101539761 B1 KR 101539761B1 KR 1020130011722 A KR1020130011722 A KR 1020130011722A KR 20130011722 A KR20130011722 A KR 20130011722A KR 101539761 B1 KR101539761 B1 KR 101539761B1
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KR
South Korea
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substituted
unsubstituted
formula
compound
group
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KR1020130011722A
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English (en)
Korean (ko)
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KR20130090360A (ko
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박애리
김봉찬
안지은
이희봉
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주식회사 엘지생명과학
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Publication of KR20130090360A publication Critical patent/KR20130090360A/ko
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Publication of KR101539761B1 publication Critical patent/KR101539761B1/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/64Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02Addition
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/62Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1020130011722A 2012-02-03 2013-02-01 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법 KR101539761B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020120011317 2012-02-03
KR20120011317 2012-02-03

Publications (2)

Publication Number Publication Date
KR20130090360A KR20130090360A (ko) 2013-08-13
KR101539761B1 true KR101539761B1 (ko) 2015-07-28

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020130011722A KR101539761B1 (ko) 2012-02-03 2013-02-01 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법

Country Status (16)

Country Link
KR (1) KR101539761B1 (fr)
CN (1) CN104159884B (fr)
AU (1) AU2013215796B2 (fr)
BR (1) BR112014018985B1 (fr)
CL (1) CL2014002029A1 (fr)
CO (1) CO7030967A2 (fr)
EA (1) EA026411B1 (fr)
MA (1) MA35906B1 (fr)
MX (1) MX355336B (fr)
MY (1) MY168411A (fr)
PE (1) PE20142331A1 (fr)
PH (1) PH12014501704A1 (fr)
SG (1) SG11201404396TA (fr)
TN (1) TN2014000329A1 (fr)
WO (1) WO2013115595A1 (fr)
ZA (1) ZA201405598B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system
CN108191647B (zh) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 2,2-二氟二羧酸二烷基酯的合成方法
CN113149823B (zh) * 2021-03-29 2023-12-08 上海青平药业有限公司 一种2-r1戊酸的制备方法
CN113354495A (zh) * 2021-05-20 2021-09-07 上海应用技术大学 一种二氟酮羰基取代不对称腈类化合物及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (fr) * 1973-12-05 1982-01-20
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
ES2299538T3 (es) * 2001-03-07 2008-06-01 Firmenich Sa Procedimiento para la preparacion de aductos de michael.
CN101903386B (zh) * 2007-12-21 2015-04-22 株式会社Lg生命科学 抑制二肽基肽酶-ⅳ的化合物、其制备方法以及含所述化合物作为活性剂的药物组合物

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Chem. Pharm. Bull. 1999, 47, 1023 *
Chem. Pharm. Bull. 2000, 48, 1023 *
J. Fluorine Chem. 2003, 121, 105 *
J. Fluorine Chem. 2004, 125, 509 *

Also Published As

Publication number Publication date
BR112014018985B1 (pt) 2021-01-19
CN104159884A (zh) 2014-11-19
SG11201404396TA (en) 2015-06-29
PE20142331A1 (es) 2015-01-17
MX355336B (es) 2018-04-16
CN104159884B (zh) 2016-01-13
ZA201405598B (en) 2015-09-30
BR112014018985A2 (fr) 2017-06-20
TN2014000329A1 (en) 2015-12-21
WO2013115595A1 (fr) 2013-08-08
BR112014018985A8 (pt) 2017-07-11
EA201491463A1 (ru) 2014-11-28
CL2014002029A1 (es) 2014-12-26
PH12014501704B1 (en) 2014-10-13
KR20130090360A (ko) 2013-08-13
MY168411A (en) 2018-11-09
AU2013215796A1 (en) 2014-08-21
EA026411B1 (ru) 2017-04-28
MA35906B1 (fr) 2014-12-01
CO7030967A2 (es) 2014-08-21
AU2013215796B2 (en) 2016-09-15
PH12014501704A1 (en) 2014-10-13
MX2014009309A (es) 2014-11-10

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