PE20142331A1 - Metodo para preparar un compuesto mediante la reaccion de adicion de michael novedosa usando agua o varios acidos como aditivo - Google Patents

Metodo para preparar un compuesto mediante la reaccion de adicion de michael novedosa usando agua o varios acidos como aditivo

Info

Publication number
PE20142331A1
PE20142331A1 PE2014001218A PE2014001218A PE20142331A1 PE 20142331 A1 PE20142331 A1 PE 20142331A1 PE 2014001218 A PE2014001218 A PE 2014001218A PE 2014001218 A PE2014001218 A PE 2014001218A PE 20142331 A1 PE20142331 A1 PE 20142331A1
Authority
PE
Peru
Prior art keywords
compound
michael
preparing
formula
acid
Prior art date
Application number
PE2014001218A
Other languages
English (en)
Inventor
Ae Ri Park
Bong Chan Kim
Ji Eun An
Hee Bong Lee
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of PE20142331A1 publication Critical patent/PE20142331A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02—Addition
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/64—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/62—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

REFERIDA A UN METODO PARA PREPARAR UN COMPUESTO DE FORMULA 1 QUE COMPRENDE ADICIONAR AGUA O ACIDO O UNA MEZCLA DE LOS MISMOS A UNA MEZCLA DE REACCION PARA PREPARAR EL COMPUESTO 1 A TRAVES DE LA REACCION DE ADICION DE MICHAEL ENTRE EL COMPUESTO DE FORMULA 2 Y EL COMPUESTO DE FORMULA 3 EN PRESENCIA DE COBRE, DONDE A ES R1-C(=O), NITRILO, ALQUILSULFONILO C1-C10, ENTRE OTROS; R1 ES H, ALQUILO C1-C10, CICLOALQUILO C3-C10, ENTRE OTROS; R2, R3 Y R4 SON H, ALQUILO C1-C10, CICLOALQUILO C3-C10, ARILO C6-C10, ENTRE OTROS; R5 Y R6 SON H, HALOGENO, ALQUILO C1-C4, ENTRE OTROS; P1 ES BENCILO, METILO, ETILO, i-PROPILO O t-BUTILO; X ES UN HALOGENO. eL ACIDO ES UN ACIDO INORGANICO TAL COMO ACIDO CLORHIDRICO, SULFURICO, NITRICO, ENTRE OTROS O UN ACIDO ORGANICO TAL COMO ACIDO FORMICO, ACETICO Y TARTARICO
PE2014001218A 2012-02-03 2013-02-01 Metodo para preparar un compuesto mediante la reaccion de adicion de michael novedosa usando agua o varios acidos como aditivo PE20142331A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20120011317 2012-02-03

Publications (1)

Publication Number Publication Date
PE20142331A1 true PE20142331A1 (es) 2015-01-17

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014001218A PE20142331A1 (es) 2012-02-03 2013-02-01 Metodo para preparar un compuesto mediante la reaccion de adicion de michael novedosa usando agua o varios acidos como aditivo

Country Status (16)

Country Link
KR (1) KR101539761B1 (es)
CN (1) CN104159884B (es)
AU (1) AU2013215796B2 (es)
BR (1) BR112014018985B1 (es)
CL (1) CL2014002029A1 (es)
CO (1) CO7030967A2 (es)
EA (1) EA026411B1 (es)
MA (1) MA35906B1 (es)
MX (1) MX355336B (es)
MY (1) MY168411A (es)
PE (1) PE20142331A1 (es)
PH (1) PH12014501704B1 (es)
SG (1) SG11201404396TA (es)
TN (1) TN2014000329A1 (es)
WO (1) WO2013115595A1 (es)
ZA (1) ZA201405598B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system
CN108191647B (zh) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 2,2-二氟二羧酸二烷基酯的合成方法
CN113149823B (zh) * 2021-03-29 2023-12-08 上海青平药业有限公司 一种2-r1戊酸的制备方法
CN113354495A (zh) * 2021-05-20 2021-09-07 上海应用技术大学 一种二氟酮羰基取代不对称腈类化合物及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (es) * 1973-12-05 1982-01-20
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
ES2299538T3 (es) * 2001-03-07 2008-06-01 Firmenich Sa Procedimiento para la preparacion de aductos de michael.
BRPI0819719B8 (pt) * 2007-12-21 2021-05-25 Lg Chemical Ltd compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo

Also Published As

Publication number Publication date
WO2013115595A1 (ko) 2013-08-08
AU2013215796A1 (en) 2014-08-21
CN104159884A (zh) 2014-11-19
SG11201404396TA (en) 2015-06-29
BR112014018985A2 (es) 2017-06-20
BR112014018985A8 (pt) 2017-07-11
MY168411A (en) 2018-11-09
MA35906B1 (fr) 2014-12-01
CO7030967A2 (es) 2014-08-21
ZA201405598B (en) 2015-09-30
CN104159884B (zh) 2016-01-13
MX2014009309A (es) 2014-11-10
MX355336B (es) 2018-04-16
EA026411B1 (ru) 2017-04-28
PH12014501704A1 (en) 2014-10-13
AU2013215796B2 (en) 2016-09-15
CL2014002029A1 (es) 2014-12-26
EA201491463A1 (ru) 2014-11-28
PH12014501704B1 (en) 2014-10-13
KR20130090360A (ko) 2013-08-13
KR101539761B1 (ko) 2015-07-28
TN2014000329A1 (en) 2015-12-21
BR112014018985B1 (pt) 2021-01-19

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