AR101136A1 - Proceso para la preparación de ácidos 3-hidroxipicolínicos - Google Patents

Proceso para la preparación de ácidos 3-hidroxipicolínicos

Info

Publication number
AR101136A1
AR101136A1 ARP150102186A ARP150102186A AR101136A1 AR 101136 A1 AR101136 A1 AR 101136A1 AR P150102186 A ARP150102186 A AR P150102186A AR P150102186 A ARP150102186 A AR P150102186A AR 101136 A1 AR101136 A1 AR 101136A1
Authority
AR
Argentina
Prior art keywords
compound
formula
preparation
alkyl
hydroxipicolinic
Prior art date
Application number
ARP150102186A
Other languages
English (en)
Inventor
James M Renga
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of AR101136A1 publication Critical patent/AR101136A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se preparan ésteres de 4,6-dibromo-3-hidroxipicolinato a partir de aminoacetatos de furan-2-ilo en un paso químico mediante una reacción de bromación-redisposición. Se reivindica compuesto intermediario. Reivindicación 1: Un proceso para la preparación del compuesto de fórmula (1) donde R² es un alquilo C₁₋₄; que comprende los siguientes pasos: a) crear una mezcla mediante el agregado de un agente de bromación y agua al compuesto de fórmula (2) donde X es Cl o Br, y R² es un alquilo C₁₋₄; y b) aislar el compuesto de fórmula (1) de la mezcla. Reivindicación 11: Un compuesto que consta de la fórmula (3), en donde R² es un alquilo C₁₋₄.
ARP150102186A 2014-07-08 2015-07-08 Proceso para la preparación de ácidos 3-hidroxipicolínicos AR101136A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462021868P 2014-07-08 2014-07-08

Publications (1)

Publication Number Publication Date
AR101136A1 true AR101136A1 (es) 2016-11-23

Family

ID=55064780

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150102186A AR101136A1 (es) 2014-07-08 2015-07-08 Proceso para la preparación de ácidos 3-hidroxipicolínicos

Country Status (15)

Country Link
US (1) US9353060B2 (es)
EP (1) EP3166928B1 (es)
JP (1) JP6560335B2 (es)
KR (1) KR102418462B1 (es)
CN (1) CN106660959B (es)
AR (1) AR101136A1 (es)
BR (1) BR112016030604B8 (es)
CA (1) CA2954268C (es)
CO (1) CO2017000010A2 (es)
ES (1) ES2726927T3 (es)
IL (1) IL249794B (es)
MX (1) MX387903B (es)
TW (1) TWI689495B (es)
WO (1) WO2016007532A1 (es)
ZA (1) ZA201700034B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10550083B2 (en) * 2016-01-22 2020-02-04 Dow Agrosciences Llc Processes for the preparation of 4-alkoxy-3-hydroxypicolinic acids
TW201733985A (zh) * 2016-02-29 2017-10-01 陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法
US10403145B2 (en) * 2017-01-19 2019-09-03 Ford Global Technologies, Llc Collison mitigation and avoidance
JP2020161992A (ja) 2019-03-27 2020-10-01 ソニーセミコンダクタソリューションズ株式会社 撮像システム及び物体認識システム
UY40356A (es) 2022-07-18 2024-01-31 Pi Industries Ltd Un proceso para la síntesis de ácidos 4-alcoxi-3-hidroxipicolínicos e intermedios de los mismos.
CN117229167B (zh) * 2023-09-08 2025-12-26 湖北梦鑫生物医药科技有限责任公司 一种农药中间体的制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0045281B1 (de) 1980-07-28 1985-05-08 Ciba-Geigy Ag Thiazolinderivate und Verfahren zu ihrer Herstellung
EP0061836B1 (en) 1981-03-19 1986-12-30 Imperial Chemical Industries Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them
GB9524104D0 (en) * 1995-11-24 1996-01-24 Smithkline Beecham Spa Novel compounds
EP1054011B1 (en) 1998-02-06 2006-09-13 Meiji Seika Kaisha Ltd. Novel antifungal compounds and process for producing the same
US6133447A (en) * 1998-02-27 2000-10-17 Novartis Crop Protection, Inc. Process for the preparation of substituted pyridines
CN1213658C (zh) 1998-11-04 2005-08-10 明治制果株式会社 吡啶甲酰胺衍生物、含有其作为有效成分的有害生物防除剂
HUP0301764A3 (en) 1999-07-20 2004-06-28 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
US20030018052A1 (en) 1999-07-20 2003-01-23 Ricks Michael J. Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
US6355660B1 (en) 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
EP1516874B1 (en) 1999-07-20 2015-08-19 Dow AgroSciences LLC Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
US20050239873A1 (en) 1999-08-20 2005-10-27 Fred Hutchinson Cancer Research Center 2 Methoxy antimycin a derivatives and methods of use
BR0013469B1 (pt) * 1999-08-20 2011-01-25 amidas aromáticas heterocìclicas fungicidas, composição fungicida compreendendo as mesmas, bem como método para o controle ou a prevenção de infestação fúngica.
AU777824B2 (en) * 1999-11-24 2004-11-04 Merck Sharp & Dohme Corp. Gamma-hydroxy-2-(fluoroalkylaminocarbonyl)-1- piperazinepentanamides as HIV protease inhibitors
CA2453577A1 (en) 2001-07-31 2003-02-13 Richard Brewer Rogers Reductive cleavage of the exocyclic ester of uk-2a or its derivatives and products formed therefrom
US6903219B2 (en) 2001-10-05 2005-06-07 Dow Agrosciences Llc Process to produce derivatives from UK-2A derivatives
AR037328A1 (es) 2001-10-23 2004-11-03 Dow Agrosciences Llc Compuesto de [7-bencil-2,6-dioxo-1,5-dioxonan-3-il]-4-metoxipiridin-2-carboxamida, composicion que lo comprende y metodo que lo utiliza
MXPA05012286A (es) 2003-05-28 2006-01-30 Basf Ag Mezclas fungicidas para combatir patogenos de arroz.
DE10347090A1 (de) 2003-10-10 2005-05-04 Bayer Cropscience Ag Synergistische fungizide Wirkstoffkombinationen
US20050176767A1 (en) 2003-10-30 2005-08-11 Laval Chan Chun Kong Pyridine carboxamide and methods for inhibiting HIV integrase
US20070275954A1 (en) 2004-05-19 2007-11-29 Astrazeneca Ab Novel Fused Heterocycles and Uses Thereof
EP2013174B1 (en) * 2006-04-11 2013-05-08 Merck Sharp & Dohme Corp. Diaryl substituted alkanes
ES2381320T3 (es) 2007-09-26 2012-05-25 Basf Se Composiciones fungicidas ternarias que comprenden boscalida y clorotalonil
WO2009155095A2 (en) 2008-05-30 2009-12-23 Dow Agrosciences Llc Methods to control qoi-resistant fungal pathogens
AU2009335818A1 (en) * 2008-12-19 2011-07-21 Abbvie Inc. Compounds and methods of use
JP5683592B2 (ja) 2009-09-01 2015-03-11 ダウ アグロサイエンシィズ エルエルシー 穀類における菌類防除のための５−フルオロピリミジン誘導体を含有する相乗性殺菌剤組成物
PL3153021T3 (pl) 2009-10-07 2019-05-31 Dow Agrosciences Llc Synergistyczne mieszaniny grzybobójcze do zwalczania grzybów w zbożach
CA2776562A1 (en) 2009-10-07 2011-04-14 Dow Agrosciences Llc Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals
BR112012013096A2 (pt) 2009-12-08 2015-09-15 Basf Se mistura agroquímica para aumentar a saúde de uma planta, composição pesticida, método para aperfeiçoamento da saúde de uma planta e uso de uma planta
AU2011333311A1 (en) 2010-11-24 2013-07-04 Stemergie Biotechnology Sa Inhibitors of the activity of Complex III of the mitochondrial electron transport chain and use thereof for treating diseases
JP6013032B2 (ja) 2011-07-08 2016-10-25 石原産業株式会社 殺菌剤組成物及び植物病害の防除方法
PL2847185T3 (pl) 2012-05-07 2017-06-30 Dow Agrosciences Llc Makrocykliczne pikolinamidy jako fungicydy
BR112014027673A2 (pt) 2012-05-07 2017-06-27 Dow Agrosciences Llc picolinamidas macrocíclicas como fungicidas
RU2014149201A (ru) 2012-05-07 2016-06-27 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Макроциклические пиколинамиды в качестве фунгицидов
EP2938191B1 (en) 2012-12-28 2018-01-31 Dow AgroSciences LLC Synergistic fungicidal mixtures for fungal control in cereals
PL2938190T3 (pl) 2012-12-31 2018-05-30 Dow Agrosciences Llc Makrocykliczne pikolinamidy jako fungicydy

Also Published As

Publication number Publication date
CO2017000010A2 (es) 2017-03-31
ZA201700034B (en) 2018-08-29
CN106660959B (zh) 2019-12-03
BR112016030604A2 (pt) 2017-08-22
IL249794A0 (en) 2017-03-30
EP3166928A4 (en) 2018-01-10
MX2016017124A (es) 2017-05-10
MX387903B (es) 2025-03-19
TW201625537A (zh) 2016-07-16
BR112016030604B8 (pt) 2022-08-23
EP3166928B1 (en) 2019-04-03
CA2954268A1 (en) 2016-01-14
TWI689495B (zh) 2020-04-01
US9353060B2 (en) 2016-05-31
WO2016007532A1 (en) 2016-01-14
CA2954268C (en) 2022-11-22
JP6560335B2 (ja) 2019-08-14
KR102418462B1 (ko) 2022-07-08
IL249794B (en) 2020-07-30
BR112016030604B1 (pt) 2021-08-24
KR20170026444A (ko) 2017-03-08
US20160009647A1 (en) 2016-01-14
ES2726927T3 (es) 2019-10-10
CN106660959A (zh) 2017-05-10
JP2017521416A (ja) 2017-08-03
EP3166928A1 (en) 2017-05-17

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