KR101466980B1 - 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용 - Google Patents

위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용 Download PDF

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KR101466980B1
KR101466980B1 KR1020077026266A KR20077026266A KR101466980B1 KR 101466980 B1 KR101466980 B1 KR 101466980B1 KR 1020077026266 A KR1020077026266 A KR 1020077026266A KR 20077026266 A KR20077026266 A KR 20077026266A KR 101466980 B1 KR101466980 B1 KR 101466980B1
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pharmaceutically acceptable
compound
prostaglandin
acceptable salt
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KR20070119753A (ko
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류지 우에노
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수캄포 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077026266A 2005-04-12 2006-04-11 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용 Expired - Fee Related KR101466980B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67023805P 2005-04-12 2005-04-12
US60/670,238 2005-04-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147010338A Division KR20140069182A (ko) 2005-04-12 2006-04-11 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자 펌프 억제제의 병용

Publications (2)

Publication Number Publication Date
KR20070119753A KR20070119753A (ko) 2007-12-20
KR101466980B1 true KR101466980B1 (ko) 2014-12-01

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KR1020077026266A Expired - Fee Related KR101466980B1 (ko) 2005-04-12 2006-04-11 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용
KR1020147010338A Ceased KR20140069182A (ko) 2005-04-12 2006-04-11 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자 펌프 억제제의 병용

Family Applications After (1)

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KR1020147010338A Ceased KR20140069182A (ko) 2005-04-12 2006-04-11 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자 펌프 억제제의 병용

Country Status (18)

Country Link
US (1) US8962688B2 (enExample)
EP (1) EP1871380B1 (enExample)
JP (2) JP5711442B2 (enExample)
KR (2) KR101466980B1 (enExample)
CN (1) CN101198334B (enExample)
AU (1) AU2006234632B2 (enExample)
BR (1) BRPI0610557A2 (enExample)
CA (1) CA2602812C (enExample)
DK (1) DK1871380T3 (enExample)
ES (1) ES2371658T3 (enExample)
IL (1) IL186374A (enExample)
NO (1) NO20075764L (enExample)
NZ (1) NZ562763A (enExample)
PL (1) PL1871380T3 (enExample)
PT (1) PT1871380E (enExample)
RU (1) RU2468800C2 (enExample)
WO (1) WO2006109881A1 (enExample)
ZA (1) ZA200709072B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2379652T3 (es) * 2002-10-23 2012-04-30 Sucampo Ag Compuestos de prostaglandina para el tratamiento de obesidad
US7868045B2 (en) * 2006-09-06 2011-01-11 Sucampo Ag Method for promoting gastrointestinal bicarbonate secretion
US20090012165A1 (en) * 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
WO2009157397A1 (ja) * 2008-06-23 2009-12-30 日本新薬株式会社 非ステロイド性抗炎症剤投与に伴う腸管傷害治療剤
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
AU2012246999A1 (en) * 2011-04-19 2013-10-17 Sucampo Ag Method for modulating cytokine activity
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
KR20160015100A (ko) 2014-07-30 2016-02-12 미래파인켐 주식회사 프로스타글란딘 중간체의 제조방법
KR20170025682A (ko) 2015-08-31 2017-03-08 미래파인켐 주식회사 프로스타글란딘 유도체의 신규한 제조방법
CN107582556A (zh) * 2017-09-15 2018-01-16 成都泠汐尚品科技有限公司 一种治疗消化性溃疡的药物复方制剂
CN108051553A (zh) * 2017-12-29 2018-05-18 武汉轻工大学 一种仔猪肠道功能保护剂的筛选方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010093822A (ko) * 1998-12-14 2001-10-29 다비드 에 질레스 신규한 제약 제형
WO2004060377A1 (en) * 2002-12-27 2004-07-22 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380709A (en) 1987-01-28 1995-01-10 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti ulcers containing same
US5225439A (en) 1987-01-28 1993-07-06 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti ulcers containing same
JPH0688966B2 (ja) * 1987-01-28 1994-11-09 株式会社アールテック・ウエノ プロスタグランジンｅ類およびそれを含む抗潰瘍剤
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5317032A (en) 1987-10-02 1994-05-31 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Prostaglandin cathartic
TW249226B (enExample) 1990-04-04 1995-06-11 Aderk Ueno Kk
CA2150287C (en) 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
KR19990036322A (ko) 1996-06-10 1999-05-25 류지 우에노 엔도텔린길항제
ATE402925T2 (de) 1999-10-15 2008-08-15 Sucampo Ag Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid
ATE433754T1 (de) * 2000-04-06 2009-07-15 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) * 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
JP4786866B2 (ja) 2001-08-31 2011-10-05 スキャンポ・アーゲー クロライドチャンネルオープナーとしてのプロスタグランジンアナログ
AR037524A1 (es) 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
US7732487B2 (en) 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
AU2004206141A1 (en) 2003-01-24 2004-08-05 Niva Shapira Synergistic compositions and methods for potentiating anti-oxidative activity
TWI367759B (en) 2003-02-20 2012-07-11 Santarus Inc A novel formulation, omeprazole antacid complex-immediate release, for rapid and sustained suppression of gastric acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010093822A (ko) * 1998-12-14 2001-10-29 다비드 에 질레스 신규한 제약 제형
WO2004060377A1 (en) * 2002-12-27 2004-07-22 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort

Also Published As

Publication number Publication date
EP1871380B1 (en) 2011-10-19
WO2006109881A1 (en) 2006-10-19
EP1871380A1 (en) 2008-01-02
NO20075764L (no) 2008-01-14
KR20140069182A (ko) 2014-06-09
CA2602812C (en) 2014-11-18
RU2468800C2 (ru) 2012-12-10
US20070276006A1 (en) 2007-11-29
RU2007141655A (ru) 2009-05-20
AU2006234632B2 (en) 2011-10-27
ES2371658T3 (es) 2012-01-05
JP5711442B2 (ja) 2015-04-30
BRPI0610557A2 (pt) 2010-06-29
IL186374A (en) 2013-05-30
JP2013121972A (ja) 2013-06-20
IL186374A0 (en) 2008-03-20
DK1871380T3 (da) 2011-11-21
JP2008535774A (ja) 2008-09-04
ZA200709072B (en) 2008-11-26
PT1871380E (pt) 2011-11-21
PL1871380T3 (pl) 2012-03-30
CN101198334B (zh) 2013-02-06
KR20070119753A (ko) 2007-12-20
CN101198334A (zh) 2008-06-11
NZ562763A (en) 2010-12-24
US8962688B2 (en) 2015-02-24
AU2006234632A1 (en) 2006-10-19
CA2602812A1 (en) 2006-10-19

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