KR101450974B1 - 의약품 오용을 방지하는 새로운 약제학적 제제 - Google Patents

의약품 오용을 방지하는 새로운 약제학적 제제 Download PDF

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KR101450974B1
KR101450974B1 KR1020127006331A KR20127006331A KR101450974B1 KR 101450974 B1 KR101450974 B1 KR 101450974B1 KR 1020127006331 A KR1020127006331 A KR 1020127006331A KR 20127006331 A KR20127006331 A KR 20127006331A KR 101450974 B1 KR101450974 B1 KR 101450974B1
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granules
active ingredient
core
group
weight
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KR20120050476A (ko
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파스칼 서플리에
크리스토프 르봉
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데브레게아 에 아쏘시에 파르마
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    • A—HUMAN NECESSITIES
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020127006331A 2009-08-12 2010-08-11 의약품 오용을 방지하는 새로운 약제학적 제제 Active KR101450974B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0955642A FR2949062B1 (fr) 2009-08-12 2009-08-12 Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
FR0955642 2009-08-12
PCT/FR2010/051697 WO2011018583A2 (fr) 2009-08-12 2010-08-11 Nouvelles formulations pharmaceutiques contre le mésusage des médicaments

Publications (2)

Publication Number Publication Date
KR20120050476A KR20120050476A (ko) 2012-05-18
KR101450974B1 true KR101450974B1 (ko) 2014-10-15

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KR1020127006331A Active KR101450974B1 (ko) 2009-08-12 2010-08-11 의약품 오용을 방지하는 새로운 약제학적 제제

Country Status (32)

Country Link
US (1) US8999392B2 (https=)
EP (1) EP2464342B1 (https=)
JP (1) JP5608746B2 (https=)
KR (1) KR101450974B1 (https=)
CN (1) CN102573801B (https=)
AR (1) AR077865A1 (https=)
AU (1) AU2010283609B2 (https=)
BR (1) BR112012003286B1 (https=)
CA (1) CA2771054C (https=)
CL (1) CL2012000377A1 (https=)
CY (1) CY1115195T1 (https=)
DK (1) DK2464342T3 (https=)
EA (1) EA021856B1 (https=)
ES (1) ES2465523T3 (https=)
FR (1) FR2949062B1 (https=)
HR (1) HRP20140452T1 (https=)
IL (1) IL218071A (https=)
IN (1) IN2012DN01859A (https=)
MA (1) MA33522B1 (https=)
MX (1) MX2012001879A (https=)
NZ (1) NZ598471A (https=)
PE (1) PE20120916A1 (https=)
PL (1) PL2464342T3 (https=)
PT (1) PT2464342E (https=)
SG (1) SG180306A1 (https=)
SI (1) SI2464342T1 (https=)
SM (1) SMT201400076B (https=)
TN (1) TN2012000069A1 (https=)
TW (1) TWI465261B (https=)
UA (1) UA104902C2 (https=)
WO (1) WO2011018583A2 (https=)
ZA (1) ZA201201712B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2938431B1 (fr) 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
EP2405754A4 (en) * 2009-03-09 2015-10-14 Relmada Therapeutics Inc PHARMACEUTICAL BUPRENORPHINE COMPOSITIONS WITH MODIFIED RELEASE
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
US9125867B2 (en) * 2010-02-24 2015-09-08 Invincible Biotechnology Diversion- and/or abuse-resistant compositions and methods for making the same
FR2968992B1 (fr) * 2010-12-16 2013-02-08 Sanofi Aventis Comprime pharmaceutique orodispersible a base de zolpidem
FR2971422B1 (fr) * 2011-02-11 2016-05-20 Debregeas Et Associes Pharma Granules d'acide gamma-hydroxybutyrique
US9173941B1 (en) 2012-08-02 2015-11-03 Jeff Shear Sustained release bittering composition
WO2015065547A1 (en) 2013-10-31 2015-05-07 Cima Labs Inc. Immediate release abuse-deterrent granulated dosage forms
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11000498B2 (en) 2016-07-22 2021-05-11 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12478604B1 (en) 2016-07-22 2025-11-25 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12186296B1 (en) 2016-07-22 2025-01-07 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
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