KR101438851B1 - Ｃ형 간염 바이러스 억제제 - Google Patents

Ｃ형 간염 바이러스 억제제 Download PDF

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Publication number
KR101438851B1
KR101438851B1 KR1020097004995A KR20097004995A KR101438851B1 KR 101438851 B1 KR101438851 B1 KR 101438851B1 KR 1020097004995 A KR1020097004995 A KR 1020097004995A KR 20097004995 A KR20097004995 A KR 20097004995A KR 101438851 B1 KR101438851 B1 KR 101438851B1
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KR
South Korea
Prior art keywords
alkyl
imidazol
aryl
heterocyclyl
carbonyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020097004995A
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English (en)
Korean (ko)
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KR20090040910A (ko
Inventor
캐롤 버챈드
마코넨 벨레마
다니엘 에이치. 데온
앤드류 씨. 굿
제이슨 굿리치
클린트 에이. 제임스
리코 라보이
오마르 디. 로페즈
알라인 마르텔
니콜라스 에이. 민웰
반 엔. 구엔
제프리 리 로마인
에드워드 에이치. 루디거
로렌스 비. 스나이더
데니스 알. 세인트 로렌트
푸캉 양
데이비드 알. 랭글리
로렌스 지. 하만
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브리스톨-마이어스 스큅 컴퍼니
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Publication of KR20090040910A publication Critical patent/KR20090040910A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020097004995A 2006-08-11 2007-08-09 Ｃ형 간염 바이러스 억제제 Expired - Fee Related KR101438851B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83699906P 2006-08-11 2006-08-11
US60/836,999 2006-08-11
PCT/US2007/075545 WO2008021928A2 (en) 2006-08-11 2007-08-09 Hepatitis c virus inhibitors

Publications (2)

Publication Number Publication Date
KR20090040910A KR20090040910A (ko) 2009-04-27
KR101438851B1 true KR101438851B1 (ko) 2014-09-11

Family

ID=38895921

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097004995A Expired - Fee Related KR101438851B1 (ko) 2006-08-11 2007-08-09 Ｃ형 간염 바이러스 억제제

Country Status (16)

Country Link
US (1) US7659270B2 (enExample)
EP (1) EP2049116B1 (enExample)
JP (1) JP5306203B2 (enExample)
KR (1) KR101438851B1 (enExample)
CN (1) CN101528232B (enExample)
AT (1) ATE547103T1 (enExample)
AU (1) AU2007286223B2 (enExample)
CA (1) CA2660628C (enExample)
EA (1) EA017348B1 (enExample)
ES (1) ES2382005T3 (enExample)
IL (1) IL196815A (enExample)
MX (1) MX2009001436A (enExample)
NO (1) NO20090453L (enExample)
NZ (1) NZ574769A (enExample)
WO (1) WO2008021928A2 (enExample)
ZA (1) ZA200900935B (enExample)

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