KR101387835B1 - 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 - Google Patents

코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 Download PDF

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Publication number
KR101387835B1
KR101387835B1 KR1020077027199A KR20077027199A KR101387835B1 KR 101387835 B1 KR101387835 B1 KR 101387835B1 KR 1020077027199 A KR1020077027199 A KR 1020077027199A KR 20077027199 A KR20077027199 A KR 20077027199A KR 101387835 B1 KR101387835 B1 KR 101387835B1
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South Korea
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weight
polymer
active ingredient
copolymer
acrylate
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Korean (ko)
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KR20080009213A (ko
Inventor
크리스티안 마이어
카린 크누펜
한스-울리히 페테라이트
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에보니크 룀 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
KR1020077027199A 2005-05-25 2006-03-03 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 Expired - Fee Related KR101387835B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005024614.1 2005-05-25
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
PCT/EP2006/001949 WO2006125483A1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit

Publications (2)

Publication Number Publication Date
KR20080009213A KR20080009213A (ko) 2008-01-25
KR101387835B1 true KR101387835B1 (ko) 2014-04-25

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KR1020077027199A Expired - Fee Related KR101387835B1 (ko) 2005-05-25 2006-03-03 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형

Country Status (15)

Country Link
US (1) US20080193522A1 (enExample)
EP (1) EP1890682B1 (enExample)
JP (1) JP5582701B2 (enExample)
KR (1) KR101387835B1 (enExample)
CN (1) CN101137354B (enExample)
BR (1) BRPI0610206B8 (enExample)
CA (1) CA2606587C (enExample)
DE (1) DE102005024614A1 (enExample)
ES (1) ES2628962T3 (enExample)
HU (1) HUE032869T2 (enExample)
IL (1) IL187535A0 (enExample)
MX (1) MX363064B (enExample)
PL (1) PL1890682T3 (enExample)
SI (1) SI1890682T1 (enExample)
WO (1) WO2006125483A1 (enExample)

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CN102026627B (zh) * 2008-03-11 2016-10-26 武田药品工业株式会社 口腔崩解固体制剂
EP2309999A1 (en) * 2008-06-26 2011-04-20 McNeil-PPC, Inc. Coated particles containing pharmaceutically active agents
BRPI0823096B8 (pt) * 2008-09-24 2022-07-05 Evonik Roehm Gmbh composição farmacêutica de opióide de liberação controlada, dependente do ph, com resistência contra a influência do etanol, processo para sua preparação, e seu uso
CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
KR101535701B1 (ko) 2008-09-24 2015-07-09 에보니크 룀 게엠베하 에탄올의 영향에 대하여 내성을 갖는 비-오피오이드용 ｐｈ-의존성 조절 방출 제약 조성물
EP2364138A2 (en) * 2008-12-08 2011-09-14 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
HUE032817T2 (en) 2009-03-18 2017-11-28 Evonik Roehm Gmbh Regulated release pharmaceutical composition comprising a coating containing neutral vinyl polymers and excipients and resistant to the influence of ethanol
CN105287434A (zh) * 2009-03-18 2016-02-03 赢创罗姆有限公司 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
KR20120003436A (ko) * 2009-03-18 2012-01-10 에보니크 룀 게엠베하 중합체 혼합물 및 부형제를 포함하는 코팅을 이용하는, 에탄올의 영향에 대한 내성을 갖는 제어 방출 제약 조성물
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
DK2490675T3 (en) * 2009-10-22 2019-04-29 Synthon Bv Pharmaceutical compositions with sevelamer
CN103501768B (zh) * 2011-06-17 2016-11-09 赢创罗姆有限公司 具有抗乙醇影响抗性的抗胃酸的药物或营养组合物
RU2016117290A (ru) 2012-10-17 2018-10-23 Метилэйшн Сайенсис Интернэшнл Срл Композиции, содержащие s-аденозилметионин и сложный эфир галловой кислоты
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
CN107708677B (zh) 2015-06-05 2021-07-13 赢创运营有限公司 耐乙醇影响的药物或保健品组合物
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6739275B2 (ja) * 2016-08-02 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬組成物
IT201700032367A1 (it) * 2017-03-23 2018-09-23 Lamberti Spa Dispersioni poliuretaniche acquose
BR112020018345A2 (pt) * 2018-03-09 2020-12-29 Evonik Operations Gmbh Polímero, mistura de polímero e seu uso, processo de preparação de uma mistura de polímero e forma de dosagem
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
JP7299595B2 (ja) 2019-06-07 2023-06-28 日本曹達株式会社 微粒子用の湿式コーティング剤
MX2021010904A (es) * 2019-06-13 2021-10-01 Evonik Operations Gmbh Composicion en polvo que comprende una mezcla de copolimeros y una celulosa soluble en agua.
CN111700871A (zh) * 2020-06-24 2020-09-25 杭州巴洛特生物科技有限公司 一种美沙拉嗪组合物及其制备方法
CN112237572A (zh) * 2020-10-28 2021-01-19 海南卫康制药(潜山)有限公司 一种富马酸沃诺拉赞片剂及其制备方法
CN114409998A (zh) * 2021-12-24 2022-04-29 浙江普利特新材料有限公司 一种蜂窝状咖啡炭复合隔音降噪聚丙烯材料及其制备方法
CN121218887A (zh) 2023-05-15 2025-12-26 博纳菲德健康有限公司 睡眠改善组合物和使用方法
CN120204161A (zh) * 2025-04-08 2025-06-27 江西英特科胜动保科技有限公司 一种氟尼辛葡甲胺颗粒及其制备方法

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Also Published As

Publication number Publication date
EP1890682A1 (de) 2008-02-27
IL187535A0 (en) 2008-03-20
WO2006125483A1 (de) 2006-11-30
HUE032869T2 (en) 2017-11-28
MX2007014024A (es) 2008-04-09
CA2606587C (en) 2015-05-26
KR20080009213A (ko) 2008-01-25
SI1890682T1 (sl) 2017-10-30
BRPI0610206B1 (pt) 2020-10-06
BRPI0610206A2 (pt) 2010-06-01
PL1890682T3 (pl) 2017-10-31
CN101137354B (zh) 2014-06-11
MX363064B (es) 2019-03-06
US20080193522A1 (en) 2008-08-14
BRPI0610206B8 (pt) 2022-07-05
JP5582701B2 (ja) 2014-09-03
ES2628962T3 (es) 2017-08-04
EP1890682B1 (de) 2017-05-03
CN101137354A (zh) 2008-03-05
DE102005024614A1 (de) 2006-11-30
HK1116341A1 (en) 2008-12-19
CA2606587A1 (en) 2006-11-30
JP2008542211A (ja) 2008-11-27

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