ES2628962T3 - Empleo de mezclas de polímeros para la producción de formas farmacéuticas revestidas, así como forma farmacéutica con revestimiento mixto polímero - Google Patents

Empleo de mezclas de polímeros para la producción de formas farmacéuticas revestidas, así como forma farmacéutica con revestimiento mixto polímero Download PDF

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Publication number
ES2628962T3
ES2628962T3 ES06723193.6T ES06723193T ES2628962T3 ES 2628962 T3 ES2628962 T3 ES 2628962T3 ES 06723193 T ES06723193 T ES 06723193T ES 2628962 T3 ES2628962 T3 ES 2628962T3
Authority
ES
Spain
Prior art keywords
weight
polymer
active product
acrylate
pharmaceutical form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES06723193.6T
Other languages
English (en)
Spanish (es)
Inventor
Christian Meier
Karin Knuppen
Hans-Ulrich Petereit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Evonik Roehm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm GmbH filed Critical Evonik Roehm GmbH
Application granted granted Critical
Publication of ES2628962T3 publication Critical patent/ES2628962T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
ES06723193.6T 2005-05-25 2006-03-03 Empleo de mezclas de polímeros para la producción de formas farmacéuticas revestidas, así como forma farmacéutica con revestimiento mixto polímero Expired - Lifetime ES2628962T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005024614 2005-05-25
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
PCT/EP2006/001949 WO2006125483A1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit

Publications (1)

Publication Number Publication Date
ES2628962T3 true ES2628962T3 (es) 2017-08-04

Family

ID=36607494

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06723193.6T Expired - Lifetime ES2628962T3 (es) 2005-05-25 2006-03-03 Empleo de mezclas de polímeros para la producción de formas farmacéuticas revestidas, así como forma farmacéutica con revestimiento mixto polímero

Country Status (15)

Country Link
US (1) US20080193522A1 (enExample)
EP (1) EP1890682B1 (enExample)
JP (1) JP5582701B2 (enExample)
KR (1) KR101387835B1 (enExample)
CN (1) CN101137354B (enExample)
BR (1) BRPI0610206B8 (enExample)
CA (1) CA2606587C (enExample)
DE (1) DE102005024614A1 (enExample)
ES (1) ES2628962T3 (enExample)
HU (1) HUE032869T2 (enExample)
IL (1) IL187535A0 (enExample)
MX (1) MX363064B (enExample)
PL (1) PL1890682T3 (enExample)
SI (1) SI1890682T1 (enExample)
WO (1) WO2006125483A1 (enExample)

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CN101801356B (zh) 2007-09-21 2016-10-19 赢创罗姆有限公司 耐受乙醇影响的非阿片类的pH依赖性受控释放的药物组合物
RU2010119041A (ru) * 2007-10-12 2011-11-20 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы лечения нарушений желудочно-кишечного тракта, независимого от потребления пищи
EP2254556A2 (en) * 2008-03-11 2010-12-01 Takeda Pharmaceutical Company Limited Orally-disintegrating solid preparation
RU2011102777A (ru) * 2008-06-26 2012-08-10 МакНЕЙЛ-ППС, ИНК. (US) Частицы с покрытием, содержащие фармацевтически активные агенты
CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
KR101528957B1 (ko) * 2008-09-24 2015-06-17 에보니크 룀 게엠베하 에탄올의 영향에 대하여 내성을 갖는 ｐｈ-의존성 조절 방출 제약학적 오피오이드 조성물
EP2326313B1 (en) * 2008-09-24 2015-03-04 Evonik Röhm GmbH Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
EP2364138A2 (en) * 2008-12-08 2011-09-14 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
JP5619130B2 (ja) 2009-03-18 2014-11-05 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ ＲｏｅｈｍＧｍｂＨ 中性ビニルポリマーおよび賦形剤を含むコーティングを使用するエタノールの影響に対する耐性を有する制御放出性医薬組成物
US20110311631A1 (en) * 2009-03-18 2011-12-22 Evonik Röhm Gmbh Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising a polymer mixture and excipients
CN105287434A (zh) * 2009-03-18 2016-02-03 赢创罗姆有限公司 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
DK2490675T3 (en) * 2009-10-22 2019-04-29 Synthon Bv Pharmaceutical compositions with sevelamer
WO2012171884A1 (en) * 2011-06-17 2012-12-20 Evonik Röhm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
KR101748053B1 (ko) 2012-10-17 2017-06-15 메틸레이션 사이언시즈 인터내셔널 에스알엘 S-아데노실메티오닌 및 갈산 에스테르가 포함된 조성물
CA3018328A1 (en) 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
CA2986188A1 (en) 2015-06-05 2016-12-08 Evonik Rohm Gmbh Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6739275B2 (ja) * 2016-08-02 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬組成物
IT201700032367A1 (it) * 2017-03-23 2018-09-23 Lamberti Spa Dispersioni poliuretaniche acquose
CN112469399A (zh) * 2018-03-09 2021-03-09 赢创运营有限公司 耐受乙醇影响的聚合物混合物
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN114026188A (zh) * 2019-06-07 2022-02-08 日本曹达株式会社 微粒用的湿式涂布剂
CN113950321A (zh) * 2019-06-13 2022-01-18 赢创运营有限公司 包含共聚物混合物和水溶性纤维素的粉末组合物
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
CN111700871A (zh) * 2020-06-24 2020-09-25 杭州巴洛特生物科技有限公司 一种美沙拉嗪组合物及其制备方法
CN112237572A (zh) * 2020-10-28 2021-01-19 海南卫康制药(潜山)有限公司 一种富马酸沃诺拉赞片剂及其制备方法
CN114409998A (zh) * 2021-12-24 2022-04-29 浙江普利特新材料有限公司 一种蜂窝状咖啡炭复合隔音降噪聚丙烯材料及其制备方法
EP4712796A2 (en) 2023-05-15 2026-03-25 Bonafide Health, LLC Sleep-improving compositions and methods of use
CN120204161A (zh) * 2025-04-08 2025-06-27 江西英特科胜动保科技有限公司 一种氟尼辛葡甲胺颗粒及其制备方法

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IT1227899B (it) * 1988-12-23 1991-05-14 Poli Ind Chimica Spa Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni
DE9414066U1 (de) * 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
CA2388560A1 (en) * 1999-08-31 2001-03-08 Grunenthal Gmbh Sustained-release form of administration containing tramadol saccharinate
DE10013029A1 (de) * 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
EP1416922A1 (en) * 2001-07-16 2004-05-12 AstraZeneca AB Pharmaceutical formulation comprising a proton pump inhibitor and antacids
CA2460132A1 (en) * 2001-10-15 2003-04-24 Roehm Gmbh & Co. Kg Use of a copolymer to produce a galenic form containing a peptide or a protein as active agent
WO2004041255A1 (en) * 2002-10-31 2004-05-21 Alza Corporation Dosage form providing ascending release of liquid formulation
ES2645930T3 (es) * 2003-01-03 2017-12-11 Supernus Pharmaceuticals, Inc. Utilización de una mezcla de dos o más materiales entéricos para regular la liberación de fármacos a través de una membrana o matriz para terapias sistémicas
MXPA04010956A (es) * 2003-01-30 2005-01-25 Roehm Gmbh Forma de dosis farmaceutica y metodo para la produccion de la misma.
BRPI0415557A (pt) * 2003-10-31 2006-12-26 Hexal Ag formulação contendo ingrediente ativo farmacêutico com revestimento

Also Published As

Publication number Publication date
KR20080009213A (ko) 2008-01-25
BRPI0610206A2 (pt) 2010-06-01
HK1116341A1 (en) 2008-12-19
MX2007014024A (es) 2008-04-09
SI1890682T1 (sl) 2017-10-30
JP5582701B2 (ja) 2014-09-03
KR101387835B1 (ko) 2014-04-25
JP2008542211A (ja) 2008-11-27
WO2006125483A1 (de) 2006-11-30
CA2606587C (en) 2015-05-26
MX363064B (es) 2019-03-06
EP1890682B1 (de) 2017-05-03
DE102005024614A1 (de) 2006-11-30
IL187535A0 (en) 2008-03-20
BRPI0610206B8 (pt) 2022-07-05
US20080193522A1 (en) 2008-08-14
CN101137354B (zh) 2014-06-11
EP1890682A1 (de) 2008-02-27
PL1890682T3 (pl) 2017-10-31
BRPI0610206B1 (pt) 2020-10-06
CA2606587A1 (en) 2006-11-30
HUE032869T2 (en) 2017-11-28
CN101137354A (zh) 2008-03-05

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