CN101137354B - 聚合物混合物在生产经包衣的药物制剂中的应用和具有混合聚合物包衣的药物制剂 - Google Patents

聚合物混合物在生产经包衣的药物制剂中的应用和具有混合聚合物包衣的药物制剂 Download PDF

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Publication number
CN101137354B
CN101137354B CN200680007508.8A CN200680007508A CN101137354B CN 101137354 B CN101137354 B CN 101137354B CN 200680007508 A CN200680007508 A CN 200680007508A CN 101137354 B CN101137354 B CN 101137354B
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weight
polymer
copolymer
cellulose
polymers
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Expired - Fee Related
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CN200680007508.8A
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Chinese (zh)
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CN101137354A (zh
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C·梅尔
K·努彭
H-U·彼德雷特
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Roma Chemical Co ltd
Evonik Operations GmbH
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Evonik Roehm GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
CN200680007508.8A 2005-05-25 2006-03-03 聚合物混合物在生产经包衣的药物制剂中的应用和具有混合聚合物包衣的药物制剂 Expired - Fee Related CN101137354B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005024614.1 2005-05-25
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
PCT/EP2006/001949 WO2006125483A1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit

Publications (2)

Publication Number Publication Date
CN101137354A CN101137354A (zh) 2008-03-05
CN101137354B true CN101137354B (zh) 2014-06-11

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CN200680007508.8A Expired - Fee Related CN101137354B (zh) 2005-05-25 2006-03-03 聚合物混合物在生产经包衣的药物制剂中的应用和具有混合聚合物包衣的药物制剂

Country Status (15)

Country Link
US (1) US20080193522A1 (enExample)
EP (1) EP1890682B1 (enExample)
JP (1) JP5582701B2 (enExample)
KR (1) KR101387835B1 (enExample)
CN (1) CN101137354B (enExample)
BR (1) BRPI0610206B8 (enExample)
CA (1) CA2606587C (enExample)
DE (1) DE102005024614A1 (enExample)
ES (1) ES2628962T3 (enExample)
HU (1) HUE032869T2 (enExample)
IL (1) IL187535A0 (enExample)
MX (1) MX363064B (enExample)
PL (1) PL1890682T3 (enExample)
SI (1) SI1890682T1 (enExample)
WO (1) WO2006125483A1 (enExample)

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KR101424653B1 (ko) 2007-09-21 2014-08-06 에보니크 룀 게엠베하 에탄올의 영향에 대하여 내성을 가지는 ｐｈ-의존성 조절 방출 제약학적 오피오이드 조성물
US9555006B2 (en) 2007-09-21 2017-01-31 Evonik Roehm Gmbh PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
WO2009049160A1 (en) * 2007-10-12 2009-04-16 Takeda Pharmaceuticals North America Methods of treating gastrointestinal disorders independent of the intake of food
AU2009224254A1 (en) 2008-03-11 2009-09-17 Takeda Pharmaceutical Company Limited Orally-disintegrating solid preparation
EP2309999A1 (en) * 2008-06-26 2011-04-20 McNeil-PPC, Inc. Coated particles containing pharmaceutically active agents
SI2341899T1 (sl) * 2008-09-24 2015-04-30 Evonik Roehm Gmbh Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola
CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
CA2738197C (en) * 2008-09-24 2016-01-05 Evonik Roehm Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
WO2010077669A2 (en) * 2008-12-08 2010-07-08 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
JP5619131B2 (ja) * 2009-03-18 2014-11-05 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ ＲｏｅｈｍＧｍｂＨ ポリマー混合物と賦形剤とを含むコーティングを使用するエタノールの影響に対する耐性を有する制御放出性医薬組成物
CA2755808C (en) * 2009-03-18 2016-01-19 Evonik Roehm Gmbh Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising neutral vinyl polymers and excipients
CN105287434A (zh) * 2009-03-18 2016-02-03 赢创罗姆有限公司 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
WO2011047700A1 (en) * 2009-10-22 2011-04-28 Synthon B.V. Pharmaceutical compositions of sevelamer
CN103501768B (zh) * 2011-06-17 2016-11-09 赢创罗姆有限公司 具有抗乙醇影响抗性的抗胃酸的药物或营养组合物
RU2016117290A (ru) 2012-10-17 2018-10-23 Метилэйшн Сайенсис Интернэшнл Срл Композиции, содержащие s-аденозилметионин и сложный эфир галловой кислоты
CA3018328A1 (en) 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
EP3302444B1 (en) 2015-06-05 2020-09-23 Evonik Operations GmbH Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6739275B2 (ja) * 2016-08-02 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬組成物
IT201700032367A1 (it) * 2017-03-23 2018-09-23 Lamberti Spa Dispersioni poliuretaniche acquose
CA3093077A1 (en) 2018-03-09 2019-09-12 Evonik Operations Gmbh Polymer mixture with resistance against the influence of ethanol
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
WO2020246463A1 (ja) * 2019-06-07 2020-12-10 日本曹達株式会社 微粒子用の湿式コーティング剤
CA3141056A1 (en) * 2019-06-13 2020-12-17 Ashish Guha Powder composition comprising a copolymer mixture and a water-soluble cellulose
CN111700871A (zh) * 2020-06-24 2020-09-25 杭州巴洛特生物科技有限公司 一种美沙拉嗪组合物及其制备方法
CN112237572A (zh) * 2020-10-28 2021-01-19 海南卫康制药(潜山)有限公司 一种富马酸沃诺拉赞片剂及其制备方法
CN114409998A (zh) * 2021-12-24 2022-04-29 浙江普利特新材料有限公司 一种蜂窝状咖啡炭复合隔音降噪聚丙烯材料及其制备方法
US12239623B2 (en) 2023-05-15 2025-03-04 Bonafide Health, Llc Sleep-improving compositions and methods of use
CN120204161A (zh) * 2025-04-08 2025-06-27 江西英特科胜动保科技有限公司 一种氟尼辛葡甲胺颗粒及其制备方法

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WO2004062577A2 (en) * 2003-01-03 2004-07-29 Shire Laboratories Inc. Two or more enteric materials to regulate drug release
CN1555256A (zh) * 2001-07-16 2004-12-15 包含质子泵抑制剂和抗酸剂的药物制剂
WO2005041934A2 (de) * 2003-10-31 2005-05-12 Hexal Ag Pharmazeutische wirkstoffhaltige formulierung mit überzug

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DE9414066U1 (de) * 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
IL148411A0 (en) * 1999-08-31 2002-09-12 Gruenenthal Chemie Delayed-action form of administration containing tramadol saccharinate
DE10013029A1 (de) * 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
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WO2004041255A1 (en) * 2002-10-31 2004-05-21 Alza Corporation Dosage form providing ascending release of liquid formulation
WO2004062577A2 (en) * 2003-01-03 2004-07-29 Shire Laboratories Inc. Two or more enteric materials to regulate drug release
WO2005041934A2 (de) * 2003-10-31 2005-05-12 Hexal Ag Pharmazeutische wirkstoffhaltige formulierung mit überzug

Also Published As

Publication number Publication date
BRPI0610206A2 (pt) 2010-06-01
CA2606587C (en) 2015-05-26
CA2606587A1 (en) 2006-11-30
WO2006125483A1 (de) 2006-11-30
KR20080009213A (ko) 2008-01-25
PL1890682T3 (pl) 2017-10-31
HK1116341A1 (en) 2008-12-19
CN101137354A (zh) 2008-03-05
DE102005024614A1 (de) 2006-11-30
BRPI0610206B8 (pt) 2022-07-05
ES2628962T3 (es) 2017-08-04
MX363064B (es) 2019-03-06
JP5582701B2 (ja) 2014-09-03
IL187535A0 (en) 2008-03-20
MX2007014024A (es) 2008-04-09
BRPI0610206B1 (pt) 2020-10-06
KR101387835B1 (ko) 2014-04-25
JP2008542211A (ja) 2008-11-27
US20080193522A1 (en) 2008-08-14
EP1890682A1 (de) 2008-02-27
EP1890682B1 (de) 2017-05-03
SI1890682T1 (sl) 2017-10-30
HUE032869T2 (en) 2017-11-28

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