KR101311562B1 - 미생물을 이용한 ｌ-아스코르브산의 생산 - Google Patents

미생물을 이용한 ｌ-아스코르브산의 생산 Download PDF

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Publication number
KR101311562B1
KR101311562B1 KR1020067003014A KR20067003014A KR101311562B1 KR 101311562 B1 KR101311562 B1 KR 101311562B1 KR 1020067003014 A KR1020067003014 A KR 1020067003014A KR 20067003014 A KR20067003014 A KR 20067003014A KR 101311562 B1 KR101311562 B1 KR 101311562B1
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KR20060064629A (ko
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알란 베리
코니 리
앤 프란코이스 메이어
마사코 신조
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디에스엠 아이피 어셋츠 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020067003014A 2003-08-14 2004-08-16 미생물을 이용한 ｌ-아스코르브산의 생산 Expired - Fee Related KR101311562B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03017677.0 2003-08-14
EP03017677 2003-08-14
PCT/CH2004/000511 WO2005017159A2 (en) 2003-08-14 2004-08-16 Microbial production of l-ascorbic acid

Publications (2)

Publication Number Publication Date
KR20060064629A KR20060064629A (ko) 2006-06-13
KR101311562B1 true KR101311562B1 (ko) 2013-09-26

Family

ID=34178381

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067003014A Expired - Fee Related KR101311562B1 (ko) 2003-08-14 2004-08-16 미생물을 이용한 ｌ-아스코르브산의 생산

Country Status (9)

Country Link
US (3) US7700723B2 (https=)
EP (2) EP1664303B1 (https=)
JP (1) JP4896718B2 (https=)
KR (1) KR101311562B1 (https=)
CN (2) CN104004776A (https=)
BR (1) BRPI0413542A (https=)
EA (1) EA009287B1 (https=)
ES (2) ES2593811T3 (https=)
WO (2) WO2005017172A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006084737A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene rcs 23
WO2006084645A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene rcs 10
US20080176297A1 (en) * 2005-02-11 2008-07-24 Bastien Chevreux Gene Rcs 21
US20080193972A1 (en) * 2005-02-11 2008-08-14 Bastian Chevreux Gene Rcs 25
WO2006084717A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene sms 02
WO2006084735A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene for coenzyme pqq synthesis protein b from gluconobacter oxydans
EP2308965A1 (en) 2005-02-11 2011-04-13 DSM IP Assets B.V. Fermentative vitamin C production
WO2006084643A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene vcs 07
WO2006084724A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene rcs 28
EP1934344B1 (en) 2005-09-08 2010-02-24 DSM IP Assets B.V. Novel gene sms 37
WO2007028601A1 (en) * 2005-09-09 2007-03-15 Dsm Ip Assets B.V. Nadp-dependent glucose dehydrogenase from gluconobacter oxydans
EP1931785A2 (en) * 2005-09-09 2008-06-18 DSMIP Assets B.V. Novel gene gms 01
FR2906817B1 (fr) * 2006-10-04 2012-04-06 Gervais Danone Sa Procede de culture pour favoriser la production de vitamine k2 par les bacteries lactiques et ses applications a la preparation de produits alimentaires
EP1918382A1 (en) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Semi-continuous cascade fermentation process for pantothenate production
EP1918383A1 (en) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Semi-continuous fermentation process for pantothenate production
WO2009087223A1 (en) * 2008-01-10 2009-07-16 Dsm Ip Assets B.V. Novel gene sms 44
CN103073601B (zh) * 2013-02-01 2015-08-19 东北制药集团股份有限公司 一种2-酮基-l-古龙酸溶液加晶种的可控浓缩结晶方法
NZ743055A (en) 2013-03-08 2020-03-27 Xyleco Inc Equipment protecting enclosures
JP2016517687A (ja) 2013-03-27 2016-06-20 サンプル テクノロジーズ，インコーポレイティド 組換えファージ及び細菌検出方法
AU2014281406A1 (en) * 2013-06-19 2016-01-21 Sample6 Technologies, Inc. Phage-based bacterial detection assay
US10076749B2 (en) 2013-08-23 2018-09-18 Boehringer Ingelheim Rcv Gmbh & Co Kg Microparticles for cell disruption and/or biomolecule recovery
WO2015148680A1 (en) * 2014-03-25 2015-10-01 Ginkgo Bioworks, Inc. Methods and genetic systems for cell engineering
CN116053017B (zh) * 2022-11-04 2023-08-22 医波(厦门)科技有限公司 一种复合磁性微球及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004101A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Enzym geeignet zur oxidation von cyclitolen und ihren derivaten
EP0911415A2 (en) * 1990-09-17 1999-04-28 F. Hoffmann-La Roche AG Microbiological manufacture of L-ascorbic acid
WO2003016508A2 (en) * 2001-08-15 2003-02-27 Cerestar Holding B.V. Process for the manufacture of 2-keto-l-gulonic acid

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082785A (en) 1987-01-30 1992-01-21 Hoffmann-La Roche Inc. Biosynthesis of 2 keto-l-gulonic acid
JP2799380B2 (ja) 1988-01-14 1998-09-17 エフ・ホフマン‐ラ ロシユ アーゲー 新規酵素
US5376544A (en) 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
EP0922759B1 (en) 1997-12-01 2004-01-28 F. Hoffmann-La Roche Ag Aldehyde dehydrogenase
US20020012979A1 (en) * 1998-06-08 2002-01-31 Alan Berry Vitamin c production in microorganisms and plants
US20050153412A1 (en) 2002-04-22 2005-07-14 Tatsuo Hoshino Aldehyde dehydrogenase II
JP2005528917A (ja) 2002-06-06 2005-09-29 ディーエスエム アイピー アセッツ ビー．ブイ． アルデヒドデヒドロゲナーゼ
AU2003299104A1 (en) 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Aldehyde dehydrogenase gene
CN100347309C (zh) 2002-09-27 2007-11-07 帝斯曼知识产权资产管理有限公司 生产维生素c的方法
ATE349547T1 (de) 2002-09-27 2007-01-15 Dsm Ip Assets Bv Mikrobielle herstellung von vitamin c
CN1914326B (zh) 2004-01-30 2012-04-18 帝斯曼知识产权资产管理有限公司 维生素c的微生物生产方法
US20080226126A1 (en) * 2005-01-31 2008-09-18 Yoshinori Ohno Object-Tracking Apparatus, Microscope System, and Object-Tracking Program
EP2308965A1 (en) 2005-02-11 2011-04-13 DSM IP Assets B.V. Fermentative vitamin C production

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0911415A2 (en) * 1990-09-17 1999-04-28 F. Hoffmann-La Roche AG Microbiological manufacture of L-ascorbic acid
WO1997004101A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Enzym geeignet zur oxidation von cyclitolen und ihren derivaten
WO2003016508A2 (en) * 2001-08-15 2003-02-27 Cerestar Holding B.V. Process for the manufacture of 2-keto-l-gulonic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Plant Physiol. 1990. Vol. 94, pp. 1492-1495. *

Also Published As

Publication number Publication date
CN1882691B (zh) 2014-05-28
CN104004776A (zh) 2014-08-27
EP2348113B1 (en) 2016-06-29
US20130217080A1 (en) 2013-08-22
US20070184534A1 (en) 2007-08-09
EP1664303A2 (en) 2006-06-07
ES2421294T3 (es) 2013-08-30
US20100203598A1 (en) 2010-08-12
WO2005017159A2 (en) 2005-02-24
JP2007502102A (ja) 2007-02-08
US8338144B2 (en) 2012-12-25
EP1664303B1 (en) 2013-04-24
EP2348113A3 (en) 2012-11-14
EA200600408A1 (ru) 2006-08-25
BRPI0413542A (pt) 2006-10-17
KR20060064629A (ko) 2006-06-13
WO2005017172A1 (en) 2005-02-24
EA009287B1 (ru) 2007-12-28
CN1882691A (zh) 2006-12-20
US7700723B2 (en) 2010-04-20
EP2348113A2 (en) 2011-07-27
JP4896718B2 (ja) 2012-03-14
ES2593811T3 (es) 2016-12-13
WO2005017159A3 (en) 2005-11-03

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