KR101301429B1 - 서방성 코팅 또는 매트릭스 및 nmda 수용체 길항제를포함하는 조성물, 대상에 대한 상기 nmda 길항제의투여 방법 - Google Patents
서방성 코팅 또는 매트릭스 및 nmda 수용체 길항제를포함하는 조성물, 대상에 대한 상기 nmda 길항제의투여 방법 Download PDFInfo
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- KR101301429B1 KR101301429B1 KR1020077014323A KR20077014323A KR101301429B1 KR 101301429 B1 KR101301429 B1 KR 101301429B1 KR 1020077014323 A KR1020077014323 A KR 1020077014323A KR 20077014323 A KR20077014323 A KR 20077014323A KR 101301429 B1 KR101301429 B1 KR 101301429B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P25/32—Alcohol-abuse
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- A61P25/36—Opioid-abuse
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63088504P | 2004-11-23 | 2004-11-23 | |
| US60/630,885 | 2004-11-23 | ||
| US63536504P | 2004-12-10 | 2004-12-10 | |
| US60/635,365 | 2004-12-10 | ||
| US63578604P | 2004-12-13 | 2004-12-13 | |
| US60/635,786 | 2004-12-13 | ||
| US11/048,002 US20050245617A1 (en) | 2004-01-29 | 2005-01-31 | Methods and compositions for the treatment of CNS-related conditions |
| US11/048,002 | 2005-01-31 | ||
| US11/058,118 US20050209218A1 (en) | 2004-02-13 | 2005-02-14 | Methods and compositions for the treatment of psychiatric conditions |
| US11/058,141 US20050245460A1 (en) | 2004-02-13 | 2005-02-14 | Methods and compositions for the treatment of epilepsy, seizure disorders, and other CNS disorders |
| US11/058,141 | 2005-02-14 | ||
| US11/058,118 | 2005-02-14 | ||
| US70185705P | 2005-07-22 | 2005-07-22 | |
| US60/701,857 | 2005-07-22 | ||
| PCT/US2005/042424 WO2006058059A2 (en) | 2004-11-23 | 2005-11-22 | Composition comprising a sustained release coating or matrix and an nmda receptor antagonist, method for administration such nmda antagonist to a subject |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20070112763A KR20070112763A (ko) | 2007-11-27 |
| KR101301429B1 true KR101301429B1 (ko) | 2013-08-30 |
Family
ID=36088318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077014323A Expired - Fee Related KR101301429B1 (ko) | 2004-11-23 | 2005-11-22 | 서방성 코팅 또는 매트릭스 및 nmda 수용체 길항제를포함하는 조성물, 대상에 대한 상기 nmda 길항제의투여 방법 |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP2343057A1 (enExample) |
| JP (2) | JP2008520736A (enExample) |
| KR (1) | KR101301429B1 (enExample) |
| AU (1) | AU2005309601A1 (enExample) |
| BR (1) | BRPI0518483A2 (enExample) |
| CA (1) | CA2588295C (enExample) |
| DE (1) | DE05852057T1 (enExample) |
| IL (1) | IL183384A0 (enExample) |
| MX (1) | MX2007006120A (enExample) |
| RU (1) | RU2404750C2 (enExample) |
| SG (1) | SG157415A1 (enExample) |
| WO (1) | WO2006058059A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005309601A1 (en) | 2004-11-23 | 2006-06-01 | Neuromolecular Pharmaceuticals, Inc. | Composition comprising a sustained release coating or matrix and an NMDA receptor antagonist, method for administration such NMDA antagonist to a subject |
| EP2623099A1 (en) | 2004-11-24 | 2013-08-07 | Neuromolecular Pharmaceuticals, Inc | Composition and method for treating neurological disease |
| US20070141148A1 (en) * | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
| JP2007246507A (ja) * | 2006-02-15 | 2007-09-27 | Kracie Seiyaku Kk | 疲労の予防・治療組成物及び予防・治療方法 |
| CN101528202A (zh) * | 2006-07-05 | 2009-09-09 | 特瓦制药工业有限公司 | 美金刚的药物组合物 |
| GB0616794D0 (en) | 2006-08-24 | 2006-10-04 | Arrow Int Ltd | Solid dosage form |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| GB0623897D0 (en) * | 2006-11-30 | 2007-01-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutical composition of memantine |
| ATE554085T1 (de) | 2006-11-30 | 2012-05-15 | Probiodrug Ag | Neue inhibitoren von glutaminylcyclase |
| DE102007009888A1 (de) * | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
| JP5930573B2 (ja) | 2007-03-01 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤の新規使用 |
| WO2008128985A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thiourea derivatives as glutaminyl cyclase inhibitors |
| EP2236160A3 (en) * | 2009-03-31 | 2011-12-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Modified release dimebolin formulations |
| PL2475428T3 (pl) | 2009-09-11 | 2015-12-31 | Probiodrug Ag | Pochodne heterocykliczne jako inhibitory cyklazy glutaminowej |
| JP5885668B2 (ja) | 2009-12-02 | 2016-03-15 | アダマス ファーマシューティカルズ, インコーポレイテッド | アマンタジン組成物および使用方法 |
| ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| DE102010024105A1 (de) * | 2010-06-17 | 2011-12-22 | Grünenthal GmbH | Transdermale Verabreichung von Memantin |
| JP2013529604A (ja) * | 2010-06-24 | 2013-07-22 | メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン | ネラメキサン複数単位剤形 |
| US20140004189A1 (en) * | 2011-01-25 | 2014-01-02 | Cadila Healthcare Limited | Modified release pharmaceutical compositions memantine |
| US9737531B2 (en) * | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| EP2686313B1 (en) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazole derivatives as inhibitors of glutaminyl cyclase |
| WO2014174564A1 (ja) * | 2013-04-22 | 2014-10-30 | 祐徳薬品工業株式会社 | メマンチン含有経皮吸収型貼付製剤 |
| WO2014199455A1 (ja) * | 2013-06-12 | 2014-12-18 | 祐徳薬品工業株式会社 | メマンチン経皮吸収型貼付製剤 |
| WO2014204933A1 (en) | 2013-06-17 | 2014-12-24 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
| EP3606550A2 (en) | 2017-04-03 | 2020-02-12 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
| CA3072764A1 (en) * | 2017-08-24 | 2019-02-28 | Adamas Pharma, Llc | Amantadine compositions, preparations thereof, and methods of use |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
| IT201800011125A1 (it) | 2018-12-14 | 2020-06-14 | Dpl Pharma S P A | Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico |
| IT202000011053A1 (it) | 2020-05-14 | 2021-11-14 | Int Health Science S R L | Composizioni orali solide comprendenti matrici monolitiche composite per la somministrazione cronotropica nel tratto gastroenterico di alimenti, integratori alimentari, nutraceutici, dispositivi medici |
| IT202000011050A1 (it) | 2020-05-14 | 2021-11-14 | Mogon Pharmaceuticals Sagl | Composizioni orali solide comprendenti matrici monolitiche composite per la somministrazione cronotropica nel tratto gastroenterico di ingredienti attivi |
| EP4190319A4 (en) | 2020-07-29 | 2024-05-01 | Novamedica Limited Liability Company | Pharmaceutical composition comprising memantine and citicoline |
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| WO2004037234A2 (en) | 2002-10-24 | 2004-05-06 | Merz Pharma Gmbh & Co. Kgaa | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors |
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2005
- 2005-11-22 AU AU2005309601A patent/AU2005309601A1/en not_active Abandoned
- 2005-11-22 DE DE05852057T patent/DE05852057T1/de active Pending
- 2005-11-22 EP EP10179758A patent/EP2343057A1/en not_active Withdrawn
- 2005-11-22 BR BRPI0518483-5A patent/BRPI0518483A2/pt not_active IP Right Cessation
- 2005-11-22 MX MX2007006120A patent/MX2007006120A/es unknown
- 2005-11-22 RU RU2007122410/15A patent/RU2404750C2/ru not_active IP Right Cessation
- 2005-11-22 EP EP05852057A patent/EP1827385B1/en not_active Revoked
- 2005-11-22 WO PCT/US2005/042424 patent/WO2006058059A2/en not_active Ceased
- 2005-11-22 CA CA2588295A patent/CA2588295C/en not_active Expired - Lifetime
- 2005-11-22 SG SG200907785-0A patent/SG157415A1/en unknown
- 2005-11-22 JP JP2007543431A patent/JP2008520736A/ja active Pending
- 2005-11-22 KR KR1020077014323A patent/KR101301429B1/ko not_active Expired - Fee Related
-
2007
- 2007-05-24 IL IL183384A patent/IL183384A0/en unknown
-
2009
- 2009-03-25 JP JP2009073540A patent/JP2009173669A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2588295A1 (en) | 2006-06-01 |
| IL183384A0 (en) | 2007-09-20 |
| RU2007122410A (ru) | 2008-12-27 |
| WO2006058059A3 (en) | 2006-07-06 |
| KR20070112763A (ko) | 2007-11-27 |
| MX2007006120A (es) | 2007-12-07 |
| EP1827385B1 (en) | 2013-03-27 |
| WO2006058059A2 (en) | 2006-06-01 |
| JP2009173669A (ja) | 2009-08-06 |
| RU2404750C2 (ru) | 2010-11-27 |
| BRPI0518483A2 (pt) | 2008-11-18 |
| JP2008520736A (ja) | 2008-06-19 |
| AU2005309601A1 (en) | 2006-06-01 |
| DE05852057T1 (de) | 2007-11-29 |
| EP2343057A1 (en) | 2011-07-13 |
| EP1827385A2 (en) | 2007-09-05 |
| SG157415A1 (en) | 2009-12-29 |
| CA2588295C (en) | 2013-10-22 |
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