KR101243577B1 - 성숙 수지상 세포 조성물 및 그의 배양 방법 - Google Patents
성숙 수지상 세포 조성물 및 그의 배양 방법 Download PDFInfo
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- KR101243577B1 KR101243577B1 KR1020077008070A KR20077008070A KR101243577B1 KR 101243577 B1 KR101243577 B1 KR 101243577B1 KR 1020077008070 A KR1020077008070 A KR 1020077008070A KR 20077008070 A KR20077008070 A KR 20077008070A KR 101243577 B1 KR101243577 B1 KR 101243577B1
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- South Korea
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- ILBZSNOGPTUKHC-UHFFFAOYSA-N CC1CN(C)C1 Chemical compound CC1CN(C)C1 ILBZSNOGPTUKHC-UHFFFAOYSA-N 0.000 description 1
- 0 COC(C*=*)N[C@@](C*C(*C(CO)C1O)OC1O)[C@]([C@@](*)O)O Chemical compound COC(C*=*)N[C@@](C*C(*C(CO)C1O)OC1O)[C@]([C@@](*)O)O 0.000 description 1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/35—Cytokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4272—Melan-A/MART
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
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- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52251204P | 2004-10-07 | 2004-10-07 | |
| US60/522,512 | 2004-10-07 | ||
| PCT/US2005/036304 WO2006042177A2 (en) | 2004-10-07 | 2005-10-07 | Mature dendritic cell compositions and methods for culturing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20070101233A KR20070101233A (ko) | 2007-10-16 |
| KR101243577B1 true KR101243577B1 (ko) | 2013-03-20 |
Family
ID=36148973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077008070A Expired - Fee Related KR101243577B1 (ko) | 2004-10-07 | 2005-10-07 | 성숙 수지상 세포 조성물 및 그의 배양 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20080145931A1 (enExample) |
| EP (2) | EP2251418B1 (enExample) |
| JP (2) | JP5269412B2 (enExample) |
| KR (1) | KR101243577B1 (enExample) |
| CN (1) | CN101080487B (enExample) |
| AT (1) | ATE489455T1 (enExample) |
| AU (1) | AU2005294150B2 (enExample) |
| CA (1) | CA2577125C (enExample) |
| DE (1) | DE602005025005D1 (enExample) |
| DK (1) | DK1809737T3 (enExample) |
| ES (1) | ES2861199T3 (enExample) |
| TW (1) | TWI382843B (enExample) |
| WO (1) | WO2006042177A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101243577B1 (ko) * | 2004-10-07 | 2013-03-20 | 아고스 쎄라퓨틱스, 인코포레이티드 | 성숙 수지상 세포 조성물 및 그의 배양 방법 |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| JP5020935B2 (ja) | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス,インコーポレイティド | 樹状細胞組成物および方法 |
| US20090074711A1 (en) * | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
| ES2520026T3 (es) | 2006-09-18 | 2014-11-11 | The Board Of Trustees Of The University Of Arkansas | Composiciones y métodos para potenciar respuestas inmunitarias |
| US8859229B2 (en) * | 2007-02-02 | 2014-10-14 | Yale University | Transient transfection with RNA |
| US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
| US9249423B2 (en) * | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
| DE102007006736B4 (de) | 2007-02-07 | 2012-01-12 | Dagmar Briechle | In-vitro Testkit zur tierversuchsfreien Bestimmung des sensibilisierenden Potentials einer Substanz |
| WO2008133983A1 (en) * | 2007-04-25 | 2008-11-06 | Immurx, Inc. | Adjuvant combinations of nkt activator, cd40 agonist, and optional antigen, the use through inducing synergistic cellular immunity |
| HUE029164T2 (hu) | 2007-09-14 | 2017-02-28 | Univ Brussel Vrije | Humán antigén-prezentáló sejtek T-sejteket stimuláló képességének fokozása és azok alkalmazása vakcinázásra |
| US9408909B2 (en) | 2007-09-14 | 2016-08-09 | Vrije Universiteit Brussel | Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination |
| EP2201100B1 (en) * | 2007-09-14 | 2016-03-16 | Vrije Universiteit Brussel | Enhancing the t-cells stimulatory capacity of human antigen presenting cells and their use in vaccination |
| BRPI0818736A2 (pt) | 2007-10-30 | 2017-06-13 | Univ Arkansas | composições e métodos para intensificar imunorrepostas à bactéria flagelada |
| CN101969990B (zh) | 2007-11-01 | 2014-07-09 | 阿肯色大学评议会 | 增强针对艾美球虫属的免疫反应的组合物和方法 |
| EP2072617A1 (en) * | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
| US20090263828A1 (en) * | 2008-04-16 | 2009-10-22 | Franco Lori | Novel assay for precursor T-cells having high proliferative capacity (PHPC-asay) |
| US8741639B2 (en) | 2008-11-14 | 2014-06-03 | Dnavec Corporation | Method for producing dendritic cells |
| CN102325790A (zh) | 2008-12-03 | 2012-01-18 | 西马生物医学计划公司 | 应用酚可溶性调控蛋白研制疫苗 |
| CN102753700A (zh) * | 2009-09-04 | 2012-10-24 | 先正达参股股份有限公司 | 增加植物中多肽表达的翻译增强子元件堆叠 |
| RU2012127811A (ru) * | 2009-12-04 | 2014-01-10 | Стем Селл Энд Ридженерэйтив Медсин Интернэшнл, Инк. | Способ получения клеток-натуральных киллеров и дендритных клеток из человеческих эмбриональных гемангиобластов, полученных из стволовых клеток |
| CN102811734B (zh) | 2010-01-21 | 2016-02-10 | 阿肯色大学评议会 | 增强免疫应答的疫苗载体和方法 |
| CN102971008B (zh) | 2010-06-09 | 2015-11-25 | 阿肯色大学评议会 | 降低弯曲菌属感染的疫苗和方法 |
| SG11201404677TA (en) * | 2011-12-12 | 2014-11-27 | Cell Medica Ltd | Process of expanding t cells |
| US9603915B2 (en) | 2013-02-14 | 2017-03-28 | The Board of Trustees of the University of Akansas | Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection |
| BR112015023024B1 (pt) | 2013-03-15 | 2022-04-19 | The Board Of Trustees Of The University Of Arkansas | Vetor de vacina e composições farmacêuticas compreendendo o mesmo |
| CN109342710A (zh) * | 2013-03-28 | 2019-02-15 | 英属哥伦比亚大学 | 微流控装置及其在多细胞分泌检测中的使用方法 |
| JP2016081562A (ja) | 2014-10-09 | 2016-05-16 | ソニー株式会社 | 表示装置、表示装置の製造方法および電子機器 |
| EP3268012A4 (en) * | 2015-03-12 | 2018-10-31 | Health Research, Inc. | Enrichment of cd16+ monocytes to improve dendritic cell vaccine quality |
| CN105670994A (zh) * | 2016-02-28 | 2016-06-15 | 深圳爱生再生医学科技有限公司 | Dc诱导剂及其应用 |
| WO2017186121A1 (zh) * | 2016-04-26 | 2017-11-02 | 科济生物医药(上海)有限公司 | 一种改善免疫应答细胞功能的方法 |
| KR102767638B1 (ko) | 2016-05-03 | 2025-02-20 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법 |
| US11779599B2 (en) | 2017-11-07 | 2023-10-10 | Coimmune, Inc. | Methods and uses for dendritic cell therapy |
| US20210277354A1 (en) * | 2018-06-19 | 2021-09-09 | Fondazione Telethon | Production of engineered dendritic cells and uses thereof |
| BR112021000620A2 (pt) * | 2018-07-15 | 2021-04-20 | Enochian BioPharma, Inc. | métodos e composições com uso de células dendríticas recombinantes para terapia contra câncer |
| CN109797209B (zh) * | 2019-01-04 | 2021-07-16 | 中国人民解放军第二军医大学 | 一种树突状细胞和/或趋化性树突状细胞和/或其趋化状态和功能的特异性生物标志物 |
| BR112021020411A2 (pt) * | 2019-04-11 | 2022-03-15 | Univ Arkansas | Aptâmeros de dna específicos para cd40 como adjuvantes de vacina |
| AU2020294700A1 (en) * | 2019-06-17 | 2022-02-03 | Renovaro Biosciences Inc. | Allogeneic T-cell-based HIV vaccine to induce cellular and humoral immunity |
| WO2025076303A1 (en) * | 2023-10-05 | 2025-04-10 | Amgen Inc. | Major histocompatibility complex (mhc)-associated peptide proteomics (mapps) assay for immunogenicity risk assessment of biotherapeutic attributes |
| US20250223554A1 (en) * | 2024-01-05 | 2025-07-10 | Renovaro Biopharma Inc. | Methods and compositions using recombinant dendritic cells for cancer therapy |
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| US5981724A (en) * | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
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| TW200630491A (en) | 2006-09-01 |
| EP2251418A1 (en) | 2010-11-17 |
| EP1809737B1 (en) | 2010-11-24 |
| JP2008515439A (ja) | 2008-05-15 |
| EP1809737A2 (en) | 2007-07-25 |
| US8822223B2 (en) | 2014-09-02 |
| HK1105997A1 (en) | 2008-02-29 |
| US20170096640A1 (en) | 2017-04-06 |
| US11248209B2 (en) | 2022-02-15 |
| ATE489455T1 (de) | 2010-12-15 |
| KR20070101233A (ko) | 2007-10-16 |
| US20080145931A1 (en) | 2008-06-19 |
| TWI382843B (zh) | 2013-01-21 |
| DE602005025005D1 (de) | 2011-01-05 |
| US9556455B2 (en) | 2017-01-31 |
| AU2005294150A1 (en) | 2006-04-20 |
| CA2577125A1 (en) | 2006-04-20 |
| CA2577125C (en) | 2016-01-12 |
| EP1809737B9 (en) | 2011-10-05 |
| JP5269412B2 (ja) | 2013-08-21 |
| WO2006042177A3 (en) | 2007-02-01 |
| DK1809737T3 (da) | 2011-03-07 |
| WO2006042177A2 (en) | 2006-04-20 |
| EP2251418B1 (en) | 2021-03-17 |
| CN101080487A (zh) | 2007-11-28 |
| CN101080487B (zh) | 2012-11-14 |
| AU2005294150B2 (en) | 2011-06-16 |
| US20060078994A1 (en) | 2006-04-13 |
| ES2861199T3 (es) | 2021-10-06 |
| JP2013121352A (ja) | 2013-06-20 |
| US20150072431A1 (en) | 2015-03-12 |
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