KR101105612B1 - 비스테로이드계 소염 진통제 함유 첩부제 - Google Patents

비스테로이드계 소염 진통제 함유 첩부제 Download PDF

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Publication number
KR101105612B1
KR101105612B1 KR1020057017273A KR20057017273A KR101105612B1 KR 101105612 B1 KR101105612 B1 KR 101105612B1 KR 1020057017273 A KR1020057017273 A KR 1020057017273A KR 20057017273 A KR20057017273 A KR 20057017273A KR 101105612 B1 KR101105612 B1 KR 101105612B1
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KR
South Korea
Prior art keywords
adhesive layer
acid
sensitive adhesive
mass
pressure
Prior art date
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Expired - Fee Related
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KR1020057017273A
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English (en)
Korean (ko)
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KR20050107804A (ko
Inventor
야스노리 다카다
고지 다나카
기요미 츠루다
Original Assignee
히사미쓰 세이야꾸 가부시키가이샤
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Publication of KR20050107804A publication Critical patent/KR20050107804A/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057017273A 2003-03-18 2004-03-18 비스테로이드계 소염 진통제 함유 첩부제 Expired - Fee Related KR101105612B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003074117 2003-03-18
JPJP-P-2003-00074117 2003-03-18
PCT/JP2004/003664 WO2004082672A1 (ja) 2003-03-18 2004-03-18 非ステロイド系消炎鎮痛剤含有貼付剤

Publications (2)

Publication Number Publication Date
KR20050107804A KR20050107804A (ko) 2005-11-15
KR101105612B1 true KR101105612B1 (ko) 2012-01-18

Family

ID=33027805

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057017273A Expired - Fee Related KR101105612B1 (ko) 2003-03-18 2004-03-18 비스테로이드계 소염 진통제 함유 첩부제

Country Status (11)

Country Link
US (1) US8034374B2 (enExample)
EP (1) EP1611884B1 (enExample)
JP (1) JP4614881B2 (enExample)
KR (1) KR101105612B1 (enExample)
CN (1) CN1761462B (enExample)
BR (1) BRPI0408457B8 (enExample)
CA (1) CA2519195C (enExample)
DK (1) DK1611884T3 (enExample)
ES (1) ES2397217T3 (enExample)
TW (1) TW200501939A (enExample)
WO (1) WO2004082672A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060182819A1 (en) * 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
KR20210103586A (ko) 2007-06-04 2021-08-23 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도
HUP0700828A2 (en) * 2007-12-20 2010-01-28 Richter Gedeon Nyrt Transdermal pharmaceutical compositions containing tolperisone alone and in combination
JP4879928B2 (ja) * 2008-03-25 2012-02-22 帝國製薬株式会社 ケトプロフェンリジン塩を含有する水性貼付剤
JP5704801B2 (ja) * 2008-08-21 2015-04-22 ニプロパッチ株式会社 粘着性組成物及び経皮吸収型製剤
JP5410070B2 (ja) * 2008-10-07 2014-02-05 久光製薬株式会社 エステル化抑制剤としての炭酸金属塩及び炭酸金属塩によるエステル化抑制方法
MX380878B (es) 2008-12-04 2025-03-12 Chongxi Yu Composiciones de alta penetracion y sus aplicaciones.
JP5686132B2 (ja) * 2010-04-13 2015-03-18 東亞合成株式会社 医療用粘着剤組成物、医療用貼付剤及び該組成物の製造方法
JP5442112B2 (ja) * 2010-04-30 2014-03-12 久光製薬株式会社 貼付剤貼付用補助器具
SE535588C2 (sv) * 2010-10-29 2012-10-02 Redsense Medical Ab Detektion av blodläckage genom påvisning av förekomsten av flyktiga ämnen
CN102000043B (zh) * 2010-11-19 2013-11-06 沈阳药科大学 氟比洛芬盐透皮贴剂及其制备方法
GB201120908D0 (en) 2011-12-06 2012-01-18 Reckitt Benckiser Healthcare Patch containing non-steroidal anti-inflammatory drug
WO2013191158A1 (ja) * 2012-06-20 2013-12-27 久光製薬株式会社 経皮吸収促進剤、及びそれを含む貼付剤
JP5629745B2 (ja) * 2012-10-23 2014-11-26 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
WO2018038949A1 (en) * 2016-08-26 2018-03-01 Kci Usa, Inc. Wound dressing with analgesic border adhesive
CN106692114A (zh) * 2016-12-27 2017-05-24 毛嘉明 新型酮洛芬贴片及其制备方法
JP7117748B2 (ja) * 2017-09-22 2022-08-15 帝國製薬株式会社 貼付剤
AU2019233449B2 (en) 2018-03-14 2024-07-25 Nippon Chemiphar Co., Ltd. Medicament for treating cough
CN109432061B (zh) * 2018-11-09 2020-10-30 北京德默高科医药技术有限公司 含有布洛芬或其结构类似物的多层经皮给药系统

Citations (2)

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Publication number Priority date Publication date Assignee Title
KR100191062B1 (ko) * 1994-09-16 1999-06-15 나카토미 히로타카 외용첩부제
JP2001302502A (ja) * 2000-04-27 2001-10-31 Saitama Daiichi Seiyaku Kk インドメタシン貼付剤

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CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
US5120545A (en) * 1990-08-03 1992-06-09 Alza Corporation Reduction or prevention of sensitization to drugs
US5639738A (en) * 1992-02-20 1997-06-17 Hyal Pharmaceutical Corporation Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs
US5945125A (en) * 1995-02-28 1999-08-31 Temple University Controlled release tablet
JP4275751B2 (ja) 1996-12-27 2009-06-10 久光製薬株式会社 外用組成物
JP4181232B2 (ja) * 1997-07-18 2008-11-12 帝國製薬株式会社 ジクロフェナクナトリウム含有油性外用貼付製剤
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
KR100360827B1 (ko) * 1999-08-14 2002-11-18 주식회사 삼양사 난용성 약물을 가용화하기 위한 고분자 조성물 및 그의 제조방법
JP4659943B2 (ja) * 2000-02-25 2011-03-30 帝三製薬株式会社 塩酸ブプレノルフィン含有貼付剤
ES2367541T3 (es) * 2000-04-18 2011-11-04 Hisamitsu Pharmaceutical Co., Inc. Parche que contiene un agente antiinflamatorio.
US6455067B1 (en) * 2000-05-24 2002-09-24 Sang-A Pharmaceutical Co., Ltd. Transdermal patch for nonsteroidal antiinflammatory drug(s)
JP4648518B2 (ja) 2000-06-01 2011-03-09 帝國製薬株式会社 ４−ビフェニル酢酸含有貼付剤
JP2002020274A (ja) 2000-06-12 2002-01-23 San-A Seiyaku Kk 非ステロイド性消炎鎮痛剤の外用貼付剤および外用貼付薬
JP2002193793A (ja) 2000-12-26 2002-07-10 Teikoku Seiyaku Co Ltd 非ステロイド系消炎鎮痛貼付剤
JP2002226366A (ja) 2001-02-02 2002-08-14 Yuutoku Yakuhin Kogyo Kk 外用貼付剤
ES2343168T3 (es) * 2001-05-31 2010-07-26 Hisamitsu Pharmaceutical Co., Inc. Parches de absorcion por via percutanea.
ES2387462T3 (es) 2002-02-19 2012-09-24 Hisamitsu Pharmaceutical Co. Inc. Emplasto de tipo absorción percutáneo

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Publication number Priority date Publication date Assignee Title
KR100191062B1 (ko) * 1994-09-16 1999-06-15 나카토미 히로타카 외용첩부제
JP2001302502A (ja) * 2000-04-27 2001-10-31 Saitama Daiichi Seiyaku Kk インドメタシン貼付剤

Also Published As

Publication number Publication date
BRPI0408457B8 (pt) 2021-05-25
ES2397217T3 (es) 2013-03-05
AU2004222442A1 (en) 2004-09-30
US8034374B2 (en) 2011-10-11
TWI321470B (enExample) 2010-03-11
CN1761462A (zh) 2006-04-19
HK1086749A1 (en) 2006-09-29
TW200501939A (en) 2005-01-16
JP4614881B2 (ja) 2011-01-19
WO2004082672A1 (ja) 2004-09-30
CN1761462B (zh) 2010-04-21
CA2519195A1 (en) 2004-09-30
US20060172002A1 (en) 2006-08-03
EP1611884A1 (en) 2006-01-04
CA2519195C (en) 2012-05-08
JPWO2004082672A1 (ja) 2006-06-22
BRPI0408457B1 (pt) 2018-11-27
KR20050107804A (ko) 2005-11-15
DK1611884T3 (da) 2012-12-10
EP1611884B1 (en) 2012-11-14
EP1611884A4 (en) 2010-02-24
BRPI0408457A (pt) 2006-04-04

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