KR101065984B1 - 테모졸로마이드 에스테르를 포함하는 약학 조성물 - Google Patents

테모졸로마이드 에스테르를 포함하는 약학 조성물 Download PDF

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Publication number
KR101065984B1
KR101065984B1 KR1020077009054A KR20077009054A KR101065984B1 KR 101065984 B1 KR101065984 B1 KR 101065984B1 KR 1020077009054 A KR1020077009054 A KR 1020077009054A KR 20077009054 A KR20077009054 A KR 20077009054A KR 101065984 B1 KR101065984 B1 KR 101065984B1
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South Korea
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carboxylate
methyl
pharmaceutical composition
tmz
oxoimidazo
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KR1020077009054A
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Korean (ko)
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KR20070062569A (ko
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용펭 왕
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탄진 탈시 그룹 컴퍼니 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020077009054A 2004-09-22 2005-09-15 테모졸로마이드 에스테르를 포함하는 약학 조성물 Expired - Fee Related KR101065984B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNA2004100720564A CN1752088A (zh) 2004-09-22 2004-09-22 含有替莫唑胺酯的药用组合物
CN200410072056.4 2004-09-22

Publications (2)

Publication Number Publication Date
KR20070062569A KR20070062569A (ko) 2007-06-15
KR101065984B1 true KR101065984B1 (ko) 2011-09-19

Family

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KR1020077009054A Expired - Fee Related KR101065984B1 (ko) 2004-09-22 2005-09-15 테모졸로마이드 에스테르를 포함하는 약학 조성물

Country Status (20)

Country Link
US (1) US7579336B2 (enExample)
EP (1) EP1798234B1 (enExample)
JP (2) JP5620046B2 (enExample)
KR (1) KR101065984B1 (enExample)
CN (1) CN1752088A (enExample)
AR (1) AR050947A1 (enExample)
AU (1) AU2005287799B2 (enExample)
BR (1) BRPI0515555A (enExample)
CA (1) CA2580910C (enExample)
DK (1) DK1798234T3 (enExample)
ES (1) ES2389376T3 (enExample)
IL (1) IL182027A (enExample)
MX (1) MX2007003366A (enExample)
MY (1) MY153713A (enExample)
NZ (1) NZ554609A (enExample)
PL (1) PL1798234T3 (enExample)
RU (1) RU2393160C2 (enExample)
UA (1) UA89795C2 (enExample)
WO (1) WO2006032190A1 (enExample)
ZA (1) ZA200702801B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1727340B (zh) * 2004-07-29 2011-05-18 天津帝士力投资控股集团有限公司 一种替莫唑胺-8-羧酸酯及其组合物
EP1808173A1 (en) * 2006-01-12 2007-07-18 Matthias Dormeyer Use of CNS penetrating anticancer compounds for the treatment of protozan diseases
US8558511B2 (en) * 2009-04-07 2013-10-15 Battelle Memorial Institute Method and apparatus for smart battery charging including a plurality of controllers each monitoring input variables
KR20140087846A (ko) * 2012-12-31 2014-07-09 주식회사 삼양바이오팜 테모졸로미드를 포함하는 안정성이 개선된 약제학적 조성물 및 이의 제조방법
RU2527258C1 (ru) * 2013-02-19 2014-08-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" 6-ЗАМЕЩЕННЫЕ 3-АЗОЛИЛИМИДАЗО[1,2-b][1,2,4,5]ТЕТРАЗИНЫ, ПРОЯВЛЯЮЩИЕ ПРОТИВООПУХОЛЕВУЮ АКТИВНОСТЬ
US10709715B2 (en) * 2017-12-03 2020-07-14 Cipla Limited Method of treating hypertension
MX2021001567A (es) * 2018-08-09 2021-04-29 Univ Illinois Compuestos de imidazotetrazina.
CN114014862A (zh) * 2021-06-28 2022-02-08 烟台大学 一种治疗脑胶质瘤的新化合物及其制备和应用
CN116947765B (zh) * 2022-06-23 2025-10-10 北京新源医疗有限责任公司 一种抗肿瘤药物前药、药物组合物及在肿瘤靶向治疗领域的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485327A (zh) 2002-09-29 2004-03-31 天津天士力集团有限公司 替莫唑胺-8-羧酸脂和-8-酰胺衍生物，它们的合成方法以及它们在制备抗癌制剂中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
MX9400434A (es) * 1993-01-14 1994-07-29 Cancer Res Campaign Tech Potenciamiento de temozolomida en celulas de tumores humanos.
CN1742723A (zh) * 2004-09-02 2006-03-08 天津倍方科技发展有限公司 含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485327A (zh) 2002-09-29 2004-03-31 天津天士力集团有限公司 替莫唑胺-8-羧酸脂和-8-酰胺衍生物，它们的合成方法以及它们在制备抗癌制剂中的应用

Also Published As

Publication number Publication date
JP5620046B2 (ja) 2014-11-05
US20080044457A1 (en) 2008-02-21
CA2580910C (en) 2011-10-25
MY153713A (en) 2015-03-13
WO2006032190A1 (en) 2006-03-30
PL1798234T3 (pl) 2012-11-30
EP1798234A4 (en) 2009-04-29
RU2393160C2 (ru) 2010-06-27
EP1798234A1 (en) 2007-06-20
KR20070062569A (ko) 2007-06-15
ES2389376T3 (es) 2012-10-25
AR050947A1 (es) 2006-12-06
BRPI0515555A (pt) 2008-07-29
EP1798234B1 (en) 2012-06-13
NZ554609A (en) 2010-06-25
HK1100440A1 (en) 2007-09-21
US7579336B2 (en) 2009-08-25
UA89795C2 (ru) 2010-03-10
IL182027A (en) 2014-05-28
JP2013028630A (ja) 2013-02-07
RU2007114948A (ru) 2008-10-27
ZA200702801B (en) 2008-08-27
CN1752088A (zh) 2006-03-29
IL182027A0 (en) 2007-07-24
DK1798234T3 (da) 2012-08-27
MX2007003366A (es) 2008-03-05
CA2580910A1 (en) 2006-03-30
JP2008513523A (ja) 2008-05-01
AU2005287799B2 (en) 2009-03-26
AU2005287799A1 (en) 2006-03-30

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