CN1485327A - 替莫唑胺-8-羧酸脂和-8-酰胺衍生物,它们的合成方法以及它们在制备抗癌制剂中的应用 - Google Patents
替莫唑胺-8-羧酸脂和-8-酰胺衍生物,它们的合成方法以及它们在制备抗癌制剂中的应用 Download PDFInfo
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- CN1485327A CN1485327A CNA021313466A CN02131346A CN1485327A CN 1485327 A CN1485327 A CN 1485327A CN A021313466 A CNA021313466 A CN A021313466A CN 02131346 A CN02131346 A CN 02131346A CN 1485327 A CN1485327 A CN 1485327A
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- methyl
- imidazolo
- oxo
- amide derivatives
- temozolomide
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Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 02131346 CN1244583C (zh) | 2002-09-29 | 2002-09-29 | 替莫唑胺-8-羧酸脂和-8-酰胺衍生物,它们的合成方法以及它们在制备抗癌制剂中的应用 |
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CN 02131346 CN1244583C (zh) | 2002-09-29 | 2002-09-29 | 替莫唑胺-8-羧酸脂和-8-酰胺衍生物,它们的合成方法以及它们在制备抗癌制剂中的应用 |
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CN1485327A true CN1485327A (zh) | 2004-03-31 |
CN1244583C CN1244583C (zh) | 2006-03-08 |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006024238A1 (fr) * | 2004-09-02 | 2006-03-09 | Tianjin North Pharma Sci-Tech Co., Ltd. | Composition pharmaceutique contenant des esters temozolomide-8-carboxyliques et utilisation des esters temozolomide-8-carboxyliques pour la fabrication de medicaments antitumoraux |
WO2006032190A1 (fr) | 2004-09-22 | 2006-03-30 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique comprenant un ester de temozolomide |
CN1727340B (zh) * | 2004-07-29 | 2011-05-18 | 天津帝士力投资控股集团有限公司 | 一种替莫唑胺-8-羧酸酯及其组合物 |
CN101190916B (zh) * | 2006-11-30 | 2011-06-08 | 天津天士力集团有限公司 | 一种抗癌化合物、其制备方法、用途及含有该化合物的组合物 |
CN110393806A (zh) * | 2019-09-05 | 2019-11-01 | 江苏师范大学 | 一种替莫唑胺聚合物前药及其制备方法与应用 |
US10995094B2 (en) * | 2016-09-22 | 2021-05-04 | The University Of Massachusetts | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease |
-
2002
- 2002-09-29 CN CN 02131346 patent/CN1244583C/zh not_active Expired - Lifetime
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1727340B (zh) * | 2004-07-29 | 2011-05-18 | 天津帝士力投资控股集团有限公司 | 一种替莫唑胺-8-羧酸酯及其组合物 |
WO2006024238A1 (fr) * | 2004-09-02 | 2006-03-09 | Tianjin North Pharma Sci-Tech Co., Ltd. | Composition pharmaceutique contenant des esters temozolomide-8-carboxyliques et utilisation des esters temozolomide-8-carboxyliques pour la fabrication de medicaments antitumoraux |
US7173021B2 (en) * | 2004-09-02 | 2007-02-06 | Tianjin North Pharm Sci-Tech Co., Ltd. | Synthesis of temozolomide esters as potent anticancer pro-drugs for topical and transdermal applications in treatments of cancers |
WO2006032190A1 (fr) | 2004-09-22 | 2006-03-30 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique comprenant un ester de temozolomide |
JP2008513523A (ja) * | 2004-09-22 | 2008-05-01 | ティエンジン テイスリー グループ カンパニー リミティッド | テモゾロマイドエステルよりなる医薬組成物 |
AU2005287799B2 (en) * | 2004-09-22 | 2009-03-26 | Jiangsu Tasly Diyi Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising temozolomide ester |
KR101065984B1 (ko) | 2004-09-22 | 2011-09-19 | 탄진 탈시 그룹 컴퍼니 리미티드 | 테모졸로마이드 에스테르를 포함하는 약학 조성물 |
JP2013028630A (ja) * | 2004-09-22 | 2013-02-07 | Tianjin Tasly Group Co Ltd | テモゾロマイドエステルよりなる医薬組成物 |
CN101190916B (zh) * | 2006-11-30 | 2011-06-08 | 天津天士力集团有限公司 | 一种抗癌化合物、其制备方法、用途及含有该化合物的组合物 |
US10995094B2 (en) * | 2016-09-22 | 2021-05-04 | The University Of Massachusetts | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease |
US11912709B2 (en) | 2016-09-22 | 2024-02-27 | University Of Massachusetts | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease |
CN110393806A (zh) * | 2019-09-05 | 2019-11-01 | 江苏师范大学 | 一种替莫唑胺聚合物前药及其制备方法与应用 |
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