KR101061017B1 - 암세포의 성장 및/또는 전이 억제용 약학 조성물 - Google Patents

암세포의 성장 및/또는 전이 억제용 약학 조성물 Download PDF

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KR101061017B1
KR101061017B1 KR1020090101003A KR20090101003A KR101061017B1 KR 101061017 B1 KR101061017 B1 KR 101061017B1 KR 1020090101003 A KR1020090101003 A KR 1020090101003A KR 20090101003 A KR20090101003 A KR 20090101003A KR 101061017 B1 KR101061017 B1 KR 101061017B1
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seq
polypeptide
pro
asp
gly
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Korean (ko)
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KR20110044374A (ko
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한장희
이선희
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(주) 수파드엘릭사
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Priority to KR1020090101003A priority Critical patent/KR101061017B1/ko
Application filed by (주) 수파드엘릭사 filed Critical (주) 수파드엘릭사
Priority to US13/503,262 priority patent/US8530421B2/en
Priority to JP2012535105A priority patent/JP5751519B2/ja
Priority to CN2010800477400A priority patent/CN102711792A/zh
Priority to EP13191090.3A priority patent/EP2692353A3/en
Priority to PCT/KR2010/005619 priority patent/WO2011049289A2/ko
Priority to EP10825114.1A priority patent/EP2491944A4/en
Publication of KR20110044374A publication Critical patent/KR20110044374A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020090101003A 2009-10-23 2009-10-23 암세포의 성장 및/또는 전이 억제용 약학 조성물 Active KR101061017B1 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
KR1020090101003A KR101061017B1 (ko) 2009-10-23 2009-10-23 암세포의 성장 및/또는 전이 억제용 약학 조성물
JP2012535105A JP5751519B2 (ja) 2009-10-23 2010-08-24 白血球の血管外遊出またはガン細胞の成長及び／もしくは転移を抑制するポリペプチドまたはその融合蛋白質
CN2010800477400A CN102711792A (zh) 2009-10-23 2010-08-24 抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白
EP13191090.3A EP2692353A3 (en) 2009-10-23 2010-08-24 Peptide LGD or fused protein thereof inhibiting the extravasation of white blood cells or the growth and/or metastasis
US13/503,262 US8530421B2 (en) 2009-10-23 2010-08-24 Isolated polypeptides used for treatment of inflammatory diseases and inhibiting cancer metastasis
PCT/KR2010/005619 WO2011049289A2 (ko) 2009-10-23 2010-08-24 백혈구의 혈관외유출 또는 암세포의 성장 및/또는 전이를 억제하는 폴리펩타이드 또는 그의 융합 단백질
EP10825114.1A EP2491944A4 (en) 2009-10-23 2010-08-24 POLYPEPTIDE OR FUSIONED PROTEIN THEREFORE FOR INHIBITING THE EXTRACATION OF LEUKOCYTES OR THE GROWTH AND / OR THE METASTASE OF CANCER CELLS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020090101003A KR101061017B1 (ko) 2009-10-23 2009-10-23 암세포의 성장 및/또는 전이 억제용 약학 조성물

Publications (2)

Publication Number Publication Date
KR20110044374A KR20110044374A (ko) 2011-04-29
KR101061017B1 true KR101061017B1 (ko) 2011-08-31

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KR1020090101003A Active KR101061017B1 (ko) 2009-10-23 2009-10-23 암세포의 성장 및/또는 전이 억제용 약학 조성물

Country Status (6)

Country Link
US (1) US8530421B2 (enExample)
EP (2) EP2692353A3 (enExample)
JP (1) JP5751519B2 (enExample)
KR (1) KR101061017B1 (enExample)
CN (1) CN102711792A (enExample)
WO (1) WO2011049289A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0689637B2 (ja) 1990-08-28 1994-11-09 株式会社荏原製作所 トンネル微気圧波低減装置
KR101644982B1 (ko) * 2015-07-23 2016-08-02 주식회사 엔솔바이오사이언스 신규 펩타이드 및 그 용도
JP6984898B2 (ja) * 2016-03-02 2021-12-22 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション マトリックス結合ナノベシクルおよびその使用
WO2018226590A1 (en) * 2017-06-05 2018-12-13 The Trustees Of Columbia University In The City Of New York Peptides as biomarkers in the diagnosis, confirmation and treatment of a neurological disorder and immunoprofiling in neurodegenerative disease
KR102268921B1 (ko) * 2019-12-10 2021-06-23 강원대학교산학협력단 p53을 활성화하는 펩타이드를 포함하는 조성물
JP2023506626A (ja) * 2019-12-11 2023-02-17 スパデリクサー インコーポレイテッド ｐ５３とＦＯＸＯ４の相互作用を阻害するペプチドを含む医薬組成物
KR20230033097A (ko) * 2021-08-27 2023-03-08 (주)티카로스 기능이 강화된 신규 키메라 항원 수용체(car)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080213279A1 (en) 2005-07-05 2008-09-04 Cornell Research Foundation, Inc. Blocking Leukocyte Emigration and Inflammation By Interfering With Cd99l2

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541087A (en) * 1994-09-14 1996-07-30 Fuji Immunopharmaceuticals Corporation Expression and export technology of proteins as immunofusins
CA2305681C (en) * 1997-09-30 2013-01-08 Peviva Ab Apoptosis-related compounds and their use
EP1133317A1 (de) * 1998-11-26 2001-09-19 Pentapharm AG Transportsystemkonjugate
US6451969B1 (en) * 1999-01-15 2002-09-17 The Burnham Institute Methods for inhibiting tumor metastasis, and peptides useful therfor
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
GB9911683D0 (en) * 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
EP1276500B1 (en) * 2000-03-13 2011-06-08 Cornell Research Foundation, Inc. Blocking leukocyte emigration and inflammation by interfering with cd99/hec2
CH694935A5 (de) * 2000-07-26 2005-09-30 Straumann Holding Ag Oberflaechenmodifizierte Implantate.
US7460960B2 (en) * 2002-05-10 2008-12-02 Epitome Biosystems, Inc. Proteome epitope tags and methods of use thereof in protein modification analysis
CN1675363A (zh) * 2002-08-21 2005-09-28 默克专利有限公司 葡萄球菌肠毒素b中的t细胞表位
US7385027B2 (en) * 2003-01-07 2008-06-10 University Of Kentucky Research Foundation Membrane-permeable peptide capable of calpain inhibition
WO2005074986A2 (en) * 2004-02-10 2005-08-18 Genobiotix Aps Bioactive species capable of interfering with a microbial toxin-antitoxin complex and methods for evaluation and use of said bioactive species
KR100793947B1 (ko) * 2006-06-30 2008-01-16 강원대학교산학협력단 암세포의 성장 및 전이 억제 활성을 갖는 폴리펩타이드또는 그의 융합 단백질
US8207128B2 (en) 2005-09-28 2012-06-26 Supadelixir Inc. Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof
KR100793949B1 (ko) * 2006-07-19 2008-01-16 강원대학교산학협력단 염증 질환의 예방 또는 치료 활성을 갖는 폴리펩타이드또는 그의 융합 단백질
KR100941678B1 (ko) * 2007-12-17 2010-02-12 강원대학교산학협력단 암세포의 전이 억제 활성을 갖는 폴리펩타이드 또는 그의융합 단백질
KR101074005B1 (ko) * 2009-02-26 2011-10-17 재단법인춘천바이오산업진흥원 백혈구의 혈관외유출 억제 활성을 갖는 폴리펩타이드 또는 그의 융합 단백질

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080213279A1 (en) 2005-07-05 2008-09-04 Cornell Research Foundation, Inc. Blocking Leukocyte Emigration and Inflammation By Interfering With Cd99l2

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Cancer Research Vol.60(18):5134-5142 (2000. 9. 15.)

Also Published As

Publication number Publication date
CN102711792A (zh) 2012-10-03
EP2491944A2 (en) 2012-08-29
EP2692353A3 (en) 2014-03-26
JP5751519B2 (ja) 2015-07-22
EP2491944A4 (en) 2013-09-11
KR20110044374A (ko) 2011-04-29
US20120245091A1 (en) 2012-09-27
US8530421B2 (en) 2013-09-10
EP2692353A2 (en) 2014-02-05
JP2013507954A (ja) 2013-03-07
WO2011049289A3 (ko) 2011-07-14
WO2011049289A2 (ko) 2011-04-28

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