CN102711792A - 抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白 - Google Patents

抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白 Download PDF

Info

Publication number
CN102711792A
CN102711792A CN2010800477400A CN201080047740A CN102711792A CN 102711792 A CN102711792 A CN 102711792A CN 2010800477400 A CN2010800477400 A CN 2010800477400A CN 201080047740 A CN201080047740 A CN 201080047740A CN 102711792 A CN102711792 A CN 102711792A
Authority
CN
China
Prior art keywords
polypeptide
seq
fusion protein
cancer cells
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800477400A
Other languages
English (en)
Chinese (zh)
Inventor
韩长熙
李京镇
李善姬
朱炫美
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supadelixir Inc
Original Assignee
Supadelixir Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supadelixir Inc filed Critical Supadelixir Inc
Publication of CN102711792A publication Critical patent/CN102711792A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN2010800477400A 2009-10-23 2010-08-24 抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白 Pending CN102711792A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020090101003A KR101061017B1 (ko) 2009-10-23 2009-10-23 암세포의 성장 및/또는 전이 억제용 약학 조성물
KR10-2009-0101003 2009-10-23
PCT/KR2010/005619 WO2011049289A2 (ko) 2009-10-23 2010-08-24 백혈구의 혈관외유출 또는 암세포의 성장 및/또는 전이를 억제하는 폴리펩타이드 또는 그의 융합 단백질

Publications (1)

Publication Number Publication Date
CN102711792A true CN102711792A (zh) 2012-10-03

Family

ID=43900764

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800477400A Pending CN102711792A (zh) 2009-10-23 2010-08-24 抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白

Country Status (6)

Country Link
US (1) US8530421B2 (enExample)
EP (2) EP2491944A4 (enExample)
JP (1) JP5751519B2 (enExample)
KR (1) KR101061017B1 (enExample)
CN (1) CN102711792A (enExample)
WO (1) WO2011049289A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0689637B2 (ja) 1990-08-28 1994-11-09 株式会社荏原製作所 トンネル微気圧波低減装置
KR101644982B1 (ko) * 2015-07-23 2016-08-02 주식회사 엔솔바이오사이언스 신규 펩타이드 및 그 용도
CN118806792A (zh) * 2016-03-02 2024-10-22 高等教育联邦系统-匹兹堡大学 结合基质的纳米囊泡及其用途
US20200095296A1 (en) * 2017-06-05 2020-03-26 The Trustees Of Columbia University In The City Of New York Use of peptides as biomarkers in the diagnosis, confirmation and treatment of a neurological disorder and tcr and/or hla immunoprofiling in neurodegenerative disease
KR102268921B1 (ko) * 2019-12-10 2021-06-23 강원대학교산학협력단 p53을 활성화하는 펩타이드를 포함하는 조성물
WO2021118212A1 (ko) * 2019-12-11 2021-06-17 강원대학교산학협력단 P53과 foxo4의 상호작용을 억제시키는 펩타이드를 포함하는 약학 조성물
KR20230033097A (ko) * 2021-08-27 2023-03-08 (주)티카로스 기능이 강화된 신규 키메라 항원 수용체(car)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007037601A1 (en) * 2005-09-28 2007-04-05 Knu-Industry Cooperation Foundation Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541087A (en) * 1994-09-14 1996-07-30 Fuji Immunopharmaceuticals Corporation Expression and export technology of proteins as immunofusins
CA2305681C (en) * 1997-09-30 2013-01-08 Peviva Ab Apoptosis-related compounds and their use
WO2000032235A1 (de) * 1998-11-26 2000-06-08 Pentapharm Ag Transportsystemkonjugate
US6451969B1 (en) * 1999-01-15 2002-09-17 The Burnham Institute Methods for inhibiting tumor metastasis, and peptides useful therfor
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
GB9911683D0 (en) * 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
CA2402530C (en) * 2000-03-13 2014-01-14 Cornell Research Foundation, Inc. Blocking leukocyte emigration and inflammation by interfering with cd99
CH694935A5 (de) * 2000-07-26 2005-09-30 Straumann Holding Ag Oberflaechenmodifizierte Implantate.
US7460960B2 (en) * 2002-05-10 2008-12-02 Epitome Biosystems, Inc. Proteome epitope tags and methods of use thereof in protein modification analysis
BR0313638A (pt) * 2002-08-21 2005-06-21 Merck Patent Ges Mit Berschron Epìtopos de células t na enterotoxina b em estafilococos
US7385027B2 (en) * 2003-01-07 2008-06-10 University Of Kentucky Research Foundation Membrane-permeable peptide capable of calpain inhibition
WO2005074986A2 (en) * 2004-02-10 2005-08-18 Genobiotix Aps Bioactive species capable of interfering with a microbial toxin-antitoxin complex and methods for evaluation and use of said bioactive species
CN101437539B (zh) 2005-07-05 2013-10-02 康奈尔研究基金会（有限公司） 通过干扰cd99l2阻断白细胞迁出和炎症
KR100793947B1 (ko) * 2006-06-30 2008-01-16 강원대학교산학협력단 암세포의 성장 및 전이 억제 활성을 갖는 폴리펩타이드또는 그의 융합 단백질
KR100793949B1 (ko) * 2006-07-19 2008-01-16 강원대학교산학협력단 염증 질환의 예방 또는 치료 활성을 갖는 폴리펩타이드또는 그의 융합 단백질
KR100941678B1 (ko) * 2007-12-17 2010-02-12 강원대학교산학협력단 암세포의 전이 억제 활성을 갖는 폴리펩타이드 또는 그의융합 단백질
KR101074005B1 (ko) * 2009-02-26 2011-10-17 재단법인춘천바이오산업진흥원 백혈구의 혈관외유출 억제 활성을 갖는 폴리펩타이드 또는 그의 융합 단백질

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007037601A1 (en) * 2005-09-28 2007-04-05 Knu-Industry Cooperation Foundation Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof

Also Published As

Publication number Publication date
US20120245091A1 (en) 2012-09-27
WO2011049289A2 (ko) 2011-04-28
JP2013507954A (ja) 2013-03-07
EP2491944A2 (en) 2012-08-29
EP2692353A3 (en) 2014-03-26
EP2491944A4 (en) 2013-09-11
US8530421B2 (en) 2013-09-10
KR20110044374A (ko) 2011-04-29
JP5751519B2 (ja) 2015-07-22
EP2692353A2 (en) 2014-02-05
WO2011049289A3 (ko) 2011-07-14
KR101061017B1 (ko) 2011-08-31

Similar Documents

Publication Publication Date Title
US6235716B1 (en) Multivalent ligands which modulate angiogenesis
CN102711792A (zh) 抑制白细胞渗出或者癌细胞生长和/或转移的多肽或其融合蛋白
CN104487081B (zh) 用于预防或治疗恶病质的组合物
CA2689296C (en) Polypeptide inhibitors of hsp27 kinase and uses therefor
WO2016011906A1 (zh) 泛素化途径相关因子在调控辅助性t细胞功能中的应用
WO2000032631A2 (en) Proteins that bind angiogenesis-inhibiting proteins, compositions and methods of use thereof
EP2859898A1 (en) Therapeutic agent, treatment method and test method for diseases associated with activation of neutrophils
CA2351558C (en) Peptide fragments having cell death inhibitory activity
JP2002528389A (ja) Ｉｌ−２及びその類似体から誘導される抗炎症性ペプチド
AU2004281838B2 (en) Novel heat shock protein 20-related polypeptides and uses therefor
KR20010043088A (ko) 신규인 폴리펩티드, 그 폴리펩티드를 코드화하는 ｃＤＮＡ및 그 용도
CN102732524B (zh) 类HRG的七鳃鳗Lj-RGD3全RGD缺失突变体Lj-112在抗肿瘤药物中的应用
CN111116756B (zh) 抑制lyn激酶引起的mlck激活的融合多肽及其应用
WO1999048924A1 (en) Endostatin derived peptides with anti-angiogenic and anti-cancer activity
US8207128B2 (en) Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof
JP4995399B2 (ja) 切断されたｂａｒｄ１タンパク質、並びにその診断上及び治療上の利用
CN115605502A (zh) 用于预防或治疗纤维化疾病的重组融合蛋白
US20100197576A1 (en) Polypeptides or fusion proteins thereof inhibiting transmigration of leucocytes or growth and/or metastasis of cancer cells
KR101233073B1 (ko) 백혈구의 혈관외유출 억제 활성 및 암세포의 전이 억제 활성을 갖는 펩타이드를 포함하는 약학 조성물
JP2001163798A (ja) サイクロフィリンを含有する造血幹細胞増殖剤
US20060287229A1 (en) Novel CD40 variants
WO2020001495A1 (zh) 一类新的Bcl10聚合抑制剂及其应用
JP2012092019A (ja) 悪性腫瘍治療剤
JPWO1994029340A1 (ja) ヒト由来腫瘍細胞増殖阻害因子
CN102212126A (zh) 具有抑制内皮细胞生长活性的重组EDI-8t蛋白

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20121003