KR100869722B1 - 퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용 - Google Patents

퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용 Download PDF

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Publication number
KR100869722B1
KR100869722B1 KR1020037008242A KR20037008242A KR100869722B1 KR 100869722 B1 KR100869722 B1 KR 100869722B1 KR 1020037008242 A KR1020037008242 A KR 1020037008242A KR 20037008242 A KR20037008242 A KR 20037008242A KR 100869722 B1 KR100869722 B1 KR 100869722B1
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South Korea
Prior art keywords
octane
azoniabicyclo
group
bromide
formula
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Expired - Fee Related
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KR1020037008242A
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English (en)
Korean (ko)
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KR20030067714A (ko
Inventor
부일알베로마리아안토니아
페르난데스포르네르마리아돌로르스
쁘라뜨퀴노네스마리아
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알미랄 에이쥐
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020037008242A 2000-12-22 2001-12-20 퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용 Expired - Fee Related KR100869722B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200003084 2000-12-22
ES200003084 2000-12-22
PCT/EP2001/015169 WO2002051841A1 (en) 2000-12-22 2001-12-20 Quinuclidine carbamate derivatives and their use as m3 antagonists

Publications (2)

Publication Number Publication Date
KR20030067714A KR20030067714A (ko) 2003-08-14
KR100869722B1 true KR100869722B1 (ko) 2008-11-21

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KR1020037008242A Expired - Fee Related KR100869722B1 (ko) 2000-12-22 2001-12-20 퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용

Country Status (32)

Country Link
US (3) US7208501B2 (cg-RX-API-DMAC7.html)
EP (1) EP1345937B1 (cg-RX-API-DMAC7.html)
JP (1) JP4445704B2 (cg-RX-API-DMAC7.html)
KR (1) KR100869722B1 (cg-RX-API-DMAC7.html)
CN (1) CN1298717C (cg-RX-API-DMAC7.html)
AR (1) AR035410A1 (cg-RX-API-DMAC7.html)
AT (1) ATE305468T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002228015B2 (cg-RX-API-DMAC7.html)
BG (1) BG107930A (cg-RX-API-DMAC7.html)
BR (1) BR0116450A (cg-RX-API-DMAC7.html)
CA (1) CA2441896A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ301323B6 (cg-RX-API-DMAC7.html)
DE (1) DE60113719T2 (cg-RX-API-DMAC7.html)
DK (1) DK1345937T3 (cg-RX-API-DMAC7.html)
EC (1) ECSP034660A (cg-RX-API-DMAC7.html)
EE (1) EE200300295A (cg-RX-API-DMAC7.html)
ES (1) ES2248409T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0303529A3 (cg-RX-API-DMAC7.html)
IL (1) IL156499A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03005583A (cg-RX-API-DMAC7.html)
MY (1) MY136674A (cg-RX-API-DMAC7.html)
NO (1) NO328707B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ526580A (cg-RX-API-DMAC7.html)
PE (1) PE20020719A1 (cg-RX-API-DMAC7.html)
PL (1) PL362989A1 (cg-RX-API-DMAC7.html)
RU (1) RU2296762C2 (cg-RX-API-DMAC7.html)
SI (1) SI1345937T1 (cg-RX-API-DMAC7.html)
SK (1) SK8002003A3 (cg-RX-API-DMAC7.html)
UA (1) UA76131C2 (cg-RX-API-DMAC7.html)
UY (1) UY27092A1 (cg-RX-API-DMAC7.html)
WO (1) WO2002051841A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200304769B (cg-RX-API-DMAC7.html)

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