KR100863922B1 - 피페리돈 유도체의 목적하는 에난티오머를 분리하는 동시에 동일 반응계에서 목적하지 않는 에난티오머를 라세미화시키는 방법 - Google Patents

피페리돈 유도체의 목적하는 에난티오머를 분리하는 동시에 동일 반응계에서 목적하지 않는 에난티오머를 라세미화시키는 방법 Download PDF

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Publication number
KR100863922B1
KR100863922B1 KR1020027016915A KR20027016915A KR100863922B1 KR 100863922 B1 KR100863922 B1 KR 100863922B1 KR 1020027016915 A KR1020027016915 A KR 1020027016915A KR 20027016915 A KR20027016915 A KR 20027016915A KR 100863922 B1 KR100863922 B1 KR 100863922B1
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KR
South Korea
Prior art keywords
enantiomers
piperidone
formula
acid
piperidone derivatives
Prior art date
Application number
KR1020027016915A
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English (en)
Korean (ko)
Other versions
KR20030016288A (ko
Inventor
헤르만 뮐러-뵈티허
게르트-라이너 브레쓸러
파울 크레이에
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of KR20030016288A publication Critical patent/KR20030016288A/ko
Application granted granted Critical
Publication of KR100863922B1 publication Critical patent/KR100863922B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020027016915A 2000-06-16 2001-06-09 피페리돈 유도체의 목적하는 에난티오머를 분리하는 동시에 동일 반응계에서 목적하지 않는 에난티오머를 라세미화시키는 방법 KR100863922B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10029851.6 2000-06-16
DE10029851A DE10029851A1 (de) 2000-06-16 2000-06-16 Enantiomerentrennung von Piperidon-Derivaten unter gleichzeitiger in situ Racemisierung des unerwünschten Enantiomers
PCT/EP2001/006552 WO2001096306A1 (fr) 2000-06-16 2001-06-09 Separation d'enantionmeres de derives de piperidone avec racemisation in situ simultanee de l'enantiomere indesirable

Publications (2)

Publication Number Publication Date
KR20030016288A KR20030016288A (ko) 2003-02-26
KR100863922B1 true KR100863922B1 (ko) 2008-10-17

Family

ID=7646064

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027016915A KR100863922B1 (ko) 2000-06-16 2001-06-09 피페리돈 유도체의 목적하는 에난티오머를 분리하는 동시에 동일 반응계에서 목적하지 않는 에난티오머를 라세미화시키는 방법

Country Status (10)

Country Link
EP (1) EP1305287A1 (fr)
JP (1) JP2004503539A (fr)
KR (1) KR100863922B1 (fr)
AR (1) AR028957A1 (fr)
AU (1) AU2001270563A1 (fr)
CA (1) CA2409614C (fr)
DE (1) DE10029851A1 (fr)
IL (2) IL153085A0 (fr)
MX (1) MXPA02012301A (fr)
WO (1) WO2001096306A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0654604A (ja) * 1992-08-07 1994-03-01 Sliontec:Kk 紫外線硬化型粘着剤を用いた播種育苗シート及びその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2173194T3 (es) * 1994-09-23 2002-10-16 Darwin Discovery Ltd Procedimiento de racemizacion utilizado para la preparacion de levobupivacaina y sus analogos.
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0654604A (ja) * 1992-08-07 1994-03-01 Sliontec:Kk 紫外線硬化型粘着剤を用いた播種育苗シート及びその製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
미국등록특허공보 제6054604호

Also Published As

Publication number Publication date
EP1305287A1 (fr) 2003-05-02
DE10029851A1 (de) 2001-12-20
CA2409614A1 (fr) 2001-12-20
MXPA02012301A (es) 2003-04-25
WO2001096306A1 (fr) 2001-12-20
CA2409614C (fr) 2008-08-05
AR028957A1 (es) 2003-05-28
IL153085A0 (en) 2003-06-24
IL153085A (en) 2008-11-26
JP2004503539A (ja) 2004-02-05
AU2001270563A1 (en) 2001-12-24
KR20030016288A (ko) 2003-02-26

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