KR100857752B1 - 아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법 - Google Patents

아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법 Download PDF

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KR100857752B1
KR100857752B1 KR1020057021327A KR20057021327A KR100857752B1 KR 100857752 B1 KR100857752 B1 KR 100857752B1 KR 1020057021327 A KR1020057021327 A KR 1020057021327A KR 20057021327 A KR20057021327 A KR 20057021327A KR 100857752 B1 KR100857752 B1 KR 100857752B1
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probnp
antibody
native
mab
natural
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KR20060003905A (ko
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폴커 클렘트
아넬리제 보르기아
안드레아스 갈루저
미하엘 그롤
클라우스 할레르마이어
크리스토프 자이델
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에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020057021327A 2003-05-12 2004-05-12 아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법 Expired - Lifetime KR100857752B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03010591.0 2003-05-12
EP03010591 2003-05-12

Related Child Applications (1)

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KR1020087000782A Division KR20080011467A (ko) 2003-05-12 2004-05-12 아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법

Publications (2)

Publication Number Publication Date
KR20060003905A KR20060003905A (ko) 2006-01-11
KR100857752B1 true KR100857752B1 (ko) 2008-09-11

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KR1020057021327A Expired - Lifetime KR100857752B1 (ko) 2003-05-12 2004-05-12 아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법
KR1020087000782A Ceased KR20080011467A (ko) 2003-05-12 2004-05-12 아미노산 41-46 에 결합하는 단일클론 항체를 이용한ｐｒｏｂｎｐ 의 검출 방법

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Country Status (15)

Country Link
US (4) US7264939B2 (https=)
EP (4) EP1625164B1 (https=)
JP (4) JP5128125B2 (https=)
KR (2) KR100857752B1 (https=)
CN (3) CN100497393C (https=)
AT (2) ATE517124T1 (https=)
AU (1) AU2004235974B2 (https=)
BR (1) BRPI0410261B8 (https=)
CA (2) CA2522747C (https=)
DK (3) DK1625164T3 (https=)
ES (3) ES2369008T3 (https=)
HU (1) HUE025169T2 (https=)
MX (1) MXPA05011826A (https=)
PL (3) PL1625164T3 (https=)
WO (2) WO2004099253A1 (https=)

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US20070037208A1 (en) * 2003-05-29 2007-02-15 Foote Robert S Method for detecting cardiac ischemia via changes in b-natriuretic peptide levels
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CN106908603B (zh) 2007-01-25 2019-04-02 霍夫曼-拉罗奇有限公司 Igfbp-7在心力衰竭评估中的用途
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CA2780301A1 (en) * 2009-11-13 2011-05-19 Bg Medicine, Inc. Risk factors and prediction of myocardial infarction
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AU2012262154B2 (en) 2011-05-31 2016-08-04 Idexx Laboratories, Inc. Detection of degradation products of feline NT-proBNP
JP6119607B2 (ja) * 2011-09-20 2017-04-26 コニカミノルタ株式会社 検体希釈用液、それを用いたキットおよび蛍光測定方法
US20140273273A1 (en) 2012-11-01 2014-09-18 Christie Mitchell Ballantyne Biomarkers to improve prediction of heart failure risk
CN103304665A (zh) * 2013-05-21 2013-09-18 上海贝西生物科技有限公司 一种抗氨基末端脑利钠肽前体单克隆抗体及其应用
EP3206032B1 (en) * 2014-10-10 2019-02-27 Akira Matsumori Method for detecting cardiac failure patient, method for discrimination of cardiac disease, test reagent for cardiac failure, test kit for cardiac failure, device for detecting cardiac failure, and program for detecting cardiac failure
EP3360570A1 (en) 2017-02-13 2018-08-15 Roche Diagnostics GmbH Antibodies recognizing genetic variants
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CN108752480B (zh) * 2018-05-30 2022-03-29 中元汇吉生物技术股份有限公司 一种免疫原组合物、其制备方法及其用途
US12400762B2 (en) 2018-12-11 2025-08-26 Eko.Ai Pte. Ltd. Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US12322100B2 (en) 2018-12-11 2025-06-03 Eko.Ai Pte. Ltd. Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
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CN111487222B (zh) * 2019-01-28 2023-11-14 上海乐合生物科技有限公司 一种检测bnp的spr芯片的制备方法
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Also Published As

Publication number Publication date
JP4834136B2 (ja) 2011-12-14
ES2548327T3 (es) 2015-10-15
EP1625164B1 (en) 2011-07-20
US7811770B2 (en) 2010-10-12
BRPI0410261B8 (pt) 2021-07-27
CA2522378C (en) 2011-03-29
US7264938B2 (en) 2007-09-04
US20070117156A1 (en) 2007-05-24
DK2256132T3 (en) 2015-07-13
BRPI0410261B1 (pt) 2020-03-10
ATE522546T1 (de) 2011-09-15
JP5128125B2 (ja) 2013-01-23
ATE517124T1 (de) 2011-08-15
ES2372282T3 (es) 2012-01-18
JP5649631B2 (ja) 2015-01-07
PL1625164T3 (pl) 2011-12-30
PL2256132T3 (pl) 2016-08-31
CN1784425A (zh) 2006-06-07
DK1625163T3 (da) 2011-12-05
DK1625164T3 (da) 2011-10-31
US7264939B2 (en) 2007-09-04
CA2522747C (en) 2012-08-14
JP2007525427A (ja) 2007-09-06
EP2256132A1 (en) 2010-12-01
JP2013018784A (ja) 2013-01-31
ES2369008T3 (es) 2011-11-24
CN101967190A (zh) 2011-02-09
US20070099241A1 (en) 2007-05-03
BRPI0410261A (pt) 2006-05-16
CN100497393C (zh) 2009-06-10
AU2004235974B2 (en) 2008-02-14
EP2949669A1 (en) 2015-12-02
CN1832964A (zh) 2006-09-13
EP2256132B1 (en) 2015-04-01
HK1097855A1 (zh) 2007-07-06
KR20080011467A (ko) 2008-02-04
US20060110775A1 (en) 2006-05-25
EP1625163B1 (en) 2011-08-31
JP2010011860A (ja) 2010-01-21
US7807380B2 (en) 2010-10-05
KR20060003905A (ko) 2006-01-11
WO2004099252A1 (en) 2004-11-18
AU2004235974A1 (en) 2004-11-18
EP1625164A1 (en) 2006-02-15
US20060110776A1 (en) 2006-05-25
MXPA05011826A (es) 2006-01-26
PL1625163T3 (pl) 2012-01-31
WO2004099253A1 (en) 2004-11-18
JP4430066B2 (ja) 2010-03-10
HUE025169T2 (en) 2016-02-29
JP2007535470A (ja) 2007-12-06
EP1625163A1 (en) 2006-02-15
CA2522378A1 (en) 2004-11-18
EP1625163B8 (en) 2011-11-02
CA2522747A1 (en) 2004-11-18

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