KR100854985B1 - 혈친화성 코팅을 함유하는 의료기, 이의 제조 방법 및 용도 - Google Patents

혈친화성 코팅을 함유하는 의료기, 이의 제조 방법 및 용도 Download PDF

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Publication number
KR100854985B1
KR100854985B1 KR1020047017957A KR20047017957A KR100854985B1 KR 100854985 B1 KR100854985 B1 KR 100854985B1 KR 1020047017957 A KR1020047017957 A KR 1020047017957A KR 20047017957 A KR20047017957 A KR 20047017957A KR 100854985 B1 KR100854985 B1 KR 100854985B1
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KR
South Korea
Prior art keywords
layer
medical device
poly
acid
hemophilic
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KR1020047017957A
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English (en)
Korean (ko)
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KR20050012237A (ko
Inventor
롤란드 호레스
마리타카타리나 린센
미첼 호프만
에리카 호프만
도나테 디비아제
볼커 파우스트
Original Assignee
헤모텍 아게
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Application filed by 헤모텍 아게 filed Critical 헤모텍 아게
Priority claimed from PCT/DE2003/001254 external-priority patent/WO2003094991A1/de
Publication of KR20050012237A publication Critical patent/KR20050012237A/ko
Application granted granted Critical
Publication of KR100854985B1 publication Critical patent/KR100854985B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/18—Use of ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
KR1020047017957A 2002-05-09 2003-04-15 혈친화성 코팅을 함유하는 의료기, 이의 제조 방법 및 용도 KR100854985B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37867602P 2002-05-09 2002-05-09
US60/378,676 2002-05-09
DE10221055.1 2002-05-10
DE10221055A DE10221055B4 (de) 2002-05-10 2002-05-10 Verbindungen zur hämokompatiblen Beschichtung von Oberflächen, Verfahren zu deren Herstellung und deren Verwendung
PCT/DE2003/001254 WO2003094991A1 (de) 2002-05-09 2003-04-15 Hemokompatibel beschichtete medizinprodukte, deren herstellung und verwendung

Publications (2)

Publication Number Publication Date
KR20050012237A KR20050012237A (ko) 2005-01-31
KR100854985B1 true KR100854985B1 (ko) 2008-08-28

Family

ID=29285308

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020047017957A KR100854985B1 (ko) 2002-05-09 2003-04-15 혈친화성 코팅을 함유하는 의료기, 이의 제조 방법 및 용도
KR1020047018023A KR100859995B1 (ko) 2002-05-09 2003-04-15 혈친화성 방식으로 표면을 코팅하기 위한 화합물 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020047018023A KR100859995B1 (ko) 2002-05-09 2003-04-15 혈친화성 방식으로 표면을 코팅하기 위한 화합물 및 방법

Country Status (3)

Country Link
KR (2) KR100854985B1 (de)
DE (2) DE10221055B4 (de)
EA (1) EA016285B1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101302703B1 (ko) 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 그라프트공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트
KR101302698B1 (ko) * 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 블락공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트.
KR20190115850A (ko) 2018-04-04 2019-10-14 울산과학기술원 인공혈관 벽 내부에 이식되는 바이오 센싱 장치

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10328815A1 (de) * 2003-06-21 2005-01-05 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Beschichtungssystem für Implantate zur Erhöhung der Gewebsverträglichkeit
DE102005040211B4 (de) 2005-08-16 2010-02-11 Maquet Cardiopulmonary Ag Verwendung von nichtionischen Estern in einer Beschichtung für mit Blut in Kontakt kommende Oberflächen und medizinische Vorrichtung
DE102008027133A1 (de) * 2008-05-30 2009-12-03 Ls Medcap Gmbh Vollsynthetisches Albumin-Analogon
DE102008059857A1 (de) * 2008-12-01 2010-06-02 Forschungsinstitut für Leder und Kunststoffbahnen gGmbH Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen
AU2010200316A1 (en) * 2009-01-30 2010-08-19 Cordis Corporation Reservoir Eluting Stent
DE102009032119A1 (de) 2009-06-26 2010-12-30 Koslar, Björn H. Gefäßprothese
DE102010010483B4 (de) * 2010-02-28 2017-02-09 Björn H. Koslar Medizinisches Implantat
RU2540468C2 (ru) * 2012-11-06 2015-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородский государственный университет им. Н.И. Лобачевского"Российская Федерация Способ получения композиционных рассасывающихся материалов на основе хитозана и полилактида
RU2679887C2 (ru) * 2015-12-14 2019-02-14 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации Способ получения материалов для высокогидрофильного покрытия гемосовместимых мембран
RU2694342C1 (ru) * 2018-05-30 2019-07-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Аминоалкилдезоксипроизводное целлюлозы, способ его получения и средство, обладающее антитромбоцитарной активностью
KR102428696B1 (ko) * 2020-10-28 2022-08-03 연세대학교 원주산학협력단 인산염 흡착능력이 향상된 혈액 투석막 및 이의 제조방법

Citations (4)

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WO1999026983A1 (en) * 1997-11-25 1999-06-03 Jenny Ja Antti Wihurin Rahasto Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
WO1999027976A1 (en) * 1997-11-28 1999-06-10 Baxter Biotech Technology S.A.R.L. Non thrombogenic polymers with compatibility with organic fluids and tissues
WO2000021584A1 (en) * 1998-10-14 2000-04-20 Boston Scientific Limited Loading and release of water-insoluble drugs
WO2001032014A2 (en) * 1999-11-01 2001-05-10 Oravax, Inc. Use of salmonella vectors for vaccination against hellicobacter infection

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SE8501613D0 (sv) * 1985-04-01 1985-04-01 Bio Carb Ab Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling
DE19724869C2 (de) * 1997-06-12 1999-05-12 Henkel Kgaa Verwendung von Citosanderivaten zur Oberflächenbeschichtung
WO2000043120A1 (en) * 1999-01-22 2000-07-27 The Dow Chemical Company Surface modified divinylbenzene resin having a hemocompatible coating

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026983A1 (en) * 1997-11-25 1999-06-03 Jenny Ja Antti Wihurin Rahasto Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
WO1999027976A1 (en) * 1997-11-28 1999-06-10 Baxter Biotech Technology S.A.R.L. Non thrombogenic polymers with compatibility with organic fluids and tissues
WO2000021584A1 (en) * 1998-10-14 2000-04-20 Boston Scientific Limited Loading and release of water-insoluble drugs
WO2001032014A2 (en) * 1999-11-01 2001-05-10 Oravax, Inc. Use of salmonella vectors for vaccination against hellicobacter infection

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101302703B1 (ko) 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 그라프트공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트
KR101302698B1 (ko) * 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 블락공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트.
KR20190115850A (ko) 2018-04-04 2019-10-14 울산과학기술원 인공혈관 벽 내부에 이식되는 바이오 센싱 장치

Also Published As

Publication number Publication date
KR100859995B1 (ko) 2008-09-25
EA016285B1 (ru) 2012-03-30
DE10221055A1 (de) 2003-11-27
EA200401484A1 (ru) 2005-06-30
KR20050012239A (ko) 2005-01-31
DE10261986B4 (de) 2008-01-31
KR20050012237A (ko) 2005-01-31
DE10261986A1 (de) 2004-03-18
DE10221055B4 (de) 2007-10-25

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