EA016285B1 - Олиго- и полисахариды для гемосовместимого покрытия, способ их получения, медицинское устройство с покрытием (варианты) и способ нанесения гемосовместимого покрытия на поверхность медицинского устройства - Google Patents

Олиго- и полисахариды для гемосовместимого покрытия, способ их получения, медицинское устройство с покрытием (варианты) и способ нанесения гемосовместимого покрытия на поверхность медицинского устройства Download PDF

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Publication number
EA016285B1
EA016285B1 EA200401484A EA200401484A EA016285B1 EA 016285 B1 EA016285 B1 EA 016285B1 EA 200401484 A EA200401484 A EA 200401484A EA 200401484 A EA200401484 A EA 200401484A EA 016285 B1 EA016285 B1 EA 016285B1
Authority
EA
Eurasian Patent Office
Prior art keywords
acid
layer
hemocompatible
heparin
biostable
Prior art date
Application number
EA200401484A
Other languages
English (en)
Russian (ru)
Other versions
EA200401484A1 (ru
Inventor
Роланд Хоррес
Марита Катарина Линсен
Михель Хофман
Волкер Фауст
Эрика Хофман
Донато Ди Биаз
Original Assignee
Хемотек Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Хемотек Аг filed Critical Хемотек Аг
Priority claimed from PCT/DE2003/001253 external-priority patent/WO2003094990A1/de
Publication of EA200401484A1 publication Critical patent/EA200401484A1/ru
Publication of EA016285B1 publication Critical patent/EA016285B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/18—Use of ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
EA200401484A 2002-05-09 2003-04-15 Олиго- и полисахариды для гемосовместимого покрытия, способ их получения, медицинское устройство с покрытием (варианты) и способ нанесения гемосовместимого покрытия на поверхность медицинского устройства EA016285B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37867602P 2002-05-09 2002-05-09
DE10221055A DE10221055B4 (de) 2002-05-10 2002-05-10 Verbindungen zur hämokompatiblen Beschichtung von Oberflächen, Verfahren zu deren Herstellung und deren Verwendung
PCT/DE2003/001253 WO2003094990A1 (de) 2002-05-09 2003-04-15 Verbindungen und verfahren zur hemokompatiblen beschichtung von oberflächen

Publications (2)

Publication Number Publication Date
EA200401484A1 EA200401484A1 (ru) 2005-06-30
EA016285B1 true EA016285B1 (ru) 2012-03-30

Family

ID=29285308

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401484A EA016285B1 (ru) 2002-05-09 2003-04-15 Олиго- и полисахариды для гемосовместимого покрытия, способ их получения, медицинское устройство с покрытием (варианты) и способ нанесения гемосовместимого покрытия на поверхность медицинского устройства

Country Status (3)

Country Link
KR (2) KR100854985B1 (de)
DE (2) DE10221055B4 (de)
EA (1) EA016285B1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2540468C2 (ru) * 2012-11-06 2015-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородский государственный университет им. Н.И. Лобачевского"Российская Федерация Способ получения композиционных рассасывающихся материалов на основе хитозана и полилактида
RU2679887C2 (ru) * 2015-12-14 2019-02-14 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации Способ получения материалов для высокогидрофильного покрытия гемосовместимых мембран
RU2694342C1 (ru) * 2018-05-30 2019-07-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Аминоалкилдезоксипроизводное целлюлозы, способ его получения и средство, обладающее антитромбоцитарной активностью

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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DE10328815A1 (de) * 2003-06-21 2005-01-05 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Beschichtungssystem für Implantate zur Erhöhung der Gewebsverträglichkeit
DE102005040211B4 (de) 2005-08-16 2010-02-11 Maquet Cardiopulmonary Ag Verwendung von nichtionischen Estern in einer Beschichtung für mit Blut in Kontakt kommende Oberflächen und medizinische Vorrichtung
DE102008027133A1 (de) * 2008-05-30 2009-12-03 Ls Medcap Gmbh Vollsynthetisches Albumin-Analogon
DE102008059857A1 (de) * 2008-12-01 2010-06-02 Forschungsinstitut für Leder und Kunststoffbahnen gGmbH Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen
AU2010200316A1 (en) * 2009-01-30 2010-08-19 Cordis Corporation Reservoir Eluting Stent
DE102009032119A1 (de) 2009-06-26 2010-12-30 Koslar, Björn H. Gefäßprothese
DE102010010483B4 (de) * 2010-02-28 2017-02-09 Björn H. Koslar Medizinisches Implantat
KR101302698B1 (ko) * 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 블락공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트.
KR101302703B1 (ko) 2011-02-28 2013-09-03 부산대학교 산학협력단 폴리하이드록시옥타노에이트와 생분해성 고분자의 그라프트공중합체 합성에 의한 약물담지체와 이를 이용한 비혈관계 약물방출형 치료용 스텐트
KR102082390B1 (ko) 2018-04-04 2020-02-27 울산과학기술원 인공혈관 벽 내부에 이식되는 바이오 센싱 장치
KR102428696B1 (ko) * 2020-10-28 2022-08-03 연세대학교 원주산학협력단 인산염 흡착능력이 향상된 혈액 투석막 및 이의 제조방법

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WO1999026983A1 (en) * 1997-11-25 1999-06-03 Jenny Ja Antti Wihurin Rahasto Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
WO1999027976A1 (en) * 1997-11-28 1999-06-10 Baxter Biotech Technology S.A.R.L. Non thrombogenic polymers with compatibility with organic fluids and tissues

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SE8501613D0 (sv) * 1985-04-01 1985-04-01 Bio Carb Ab Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling
DE19724869C2 (de) * 1997-06-12 1999-05-12 Henkel Kgaa Verwendung von Citosanderivaten zur Oberflächenbeschichtung
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6585975B1 (en) * 1998-04-30 2003-07-01 Acambis, Inc. Use of Salmonella vectors for vaccination against helicobacter infection
WO2000043120A1 (en) * 1999-01-22 2000-07-27 The Dow Chemical Company Surface modified divinylbenzene resin having a hemocompatible coating

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026983A1 (en) * 1997-11-25 1999-06-03 Jenny Ja Antti Wihurin Rahasto Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
WO1999027976A1 (en) * 1997-11-28 1999-06-10 Baxter Biotech Technology S.A.R.L. Non thrombogenic polymers with compatibility with organic fluids and tissues

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2540468C2 (ru) * 2012-11-06 2015-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородский государственный университет им. Н.И. Лобачевского"Российская Федерация Способ получения композиционных рассасывающихся материалов на основе хитозана и полилактида
RU2679887C2 (ru) * 2015-12-14 2019-02-14 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации Способ получения материалов для высокогидрофильного покрытия гемосовместимых мембран
RU2694342C1 (ru) * 2018-05-30 2019-07-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Аминоалкилдезоксипроизводное целлюлозы, способ его получения и средство, обладающее антитромбоцитарной активностью

Also Published As

Publication number Publication date
KR100859995B1 (ko) 2008-09-25
DE10221055A1 (de) 2003-11-27
EA200401484A1 (ru) 2005-06-30
KR20050012239A (ko) 2005-01-31
KR100854985B1 (ko) 2008-08-28
DE10261986B4 (de) 2008-01-31
KR20050012237A (ko) 2005-01-31
DE10261986A1 (de) 2004-03-18
DE10221055B4 (de) 2007-10-25

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU