KR100810066B1 - 투명 수용성 마취제 조성물 - Google Patents

투명 수용성 마취제 조성물 Download PDF

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Publication number
KR100810066B1
KR100810066B1 KR1020027017362A KR20027017362A KR100810066B1 KR 100810066 B1 KR100810066 B1 KR 100810066B1 KR 1020027017362 A KR1020027017362 A KR 1020027017362A KR 20027017362 A KR20027017362 A KR 20027017362A KR 100810066 B1 KR100810066 B1 KR 100810066B1
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KR
South Korea
Prior art keywords
propofol
water
soluble
pharmaceutical composition
hpbcd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020027017362A
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English (en)
Korean (ko)
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KR20030023875A (ko
Inventor
스리칸쓰 파이
상기타 리반카르
쉴파 코카레카르
Original Assignee
바라트 쎄럼스 앤드 백신스 리미티드
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Publication of KR20030023875A publication Critical patent/KR20030023875A/ko
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020027017362A 2000-06-21 2000-12-14 투명 수용성 마취제 조성물 Expired - Fee Related KR100810066B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN573/MUM/2000 2000-06-21
IN573MU2000 IN187686B (cg-RX-API-DMAC10.html) 2000-06-21 2000-06-21
PCT/IN2000/000124 WO2001097796A1 (en) 2000-06-21 2000-12-14 Clear aqueous anaesthetic composition

Publications (2)

Publication Number Publication Date
KR20030023875A KR20030023875A (ko) 2003-03-20
KR100810066B1 true KR100810066B1 (ko) 2008-03-05

Family

ID=11097257

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027017362A Expired - Fee Related KR100810066B1 (ko) 2000-06-21 2000-12-14 투명 수용성 마취제 조성물

Country Status (26)

Country Link
US (1) US7138387B2 (cg-RX-API-DMAC10.html)
EP (1) EP1299095B1 (cg-RX-API-DMAC10.html)
JP (1) JP4907833B2 (cg-RX-API-DMAC10.html)
KR (1) KR100810066B1 (cg-RX-API-DMAC10.html)
CN (1) CN1254237C (cg-RX-API-DMAC10.html)
AP (1) AP2002002674A0 (cg-RX-API-DMAC10.html)
AT (1) ATE267592T1 (cg-RX-API-DMAC10.html)
AU (2) AU2001235972B2 (cg-RX-API-DMAC10.html)
BG (1) BG107463A (cg-RX-API-DMAC10.html)
BR (1) BR0017268A (cg-RX-API-DMAC10.html)
CA (1) CA2414064C (cg-RX-API-DMAC10.html)
DE (1) DE60011149T2 (cg-RX-API-DMAC10.html)
DK (1) DK1299095T3 (cg-RX-API-DMAC10.html)
EA (1) EA005589B1 (cg-RX-API-DMAC10.html)
ES (1) ES2222271T3 (cg-RX-API-DMAC10.html)
HU (1) HUP0301646A3 (cg-RX-API-DMAC10.html)
IL (1) IL153387A0 (cg-RX-API-DMAC10.html)
IN (1) IN187686B (cg-RX-API-DMAC10.html)
MX (1) MXPA02012611A (cg-RX-API-DMAC10.html)
NO (1) NO20025999D0 (cg-RX-API-DMAC10.html)
NZ (1) NZ523643A (cg-RX-API-DMAC10.html)
PL (1) PL359624A1 (cg-RX-API-DMAC10.html)
PT (1) PT1299095E (cg-RX-API-DMAC10.html)
WO (1) WO2001097796A1 (cg-RX-API-DMAC10.html)
YU (1) YU2703A (cg-RX-API-DMAC10.html)
ZA (1) ZA200300336B (cg-RX-API-DMAC10.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN188917B (cg-RX-API-DMAC10.html) * 2000-12-07 2002-11-23 Bharat Surums & Vaccines Ltd
US7034013B2 (en) 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
US20050042280A1 (en) * 2001-12-28 2005-02-24 Rogers Tracey L. Aqueous based pharmaceutical formulations of water-soluble prodrugs of propofol
JP2005522422A (ja) * 2002-02-01 2005-07-28 シモダ、バイオテック（プロプライエタリー）リミテッド 医薬組成物
US7550155B2 (en) 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
HRP20050182A2 (en) 2002-07-29 2006-11-30 Transform Pharmaceuticals Aqueous 2,6-diisopropylphenol pharmaceutical compositions
EP1585548B1 (en) * 2002-12-09 2018-06-27 Abraxis BioScience, LLC Compositions and methods of delivery of pharmacological agents
KR20060130646A (ko) * 2004-01-14 2006-12-19 가부시키가이샤 오츠까 세이야꾸 고죠 프로포폴 함유 지방 유제
KR20070058608A (ko) * 2004-09-13 2007-06-08 바라트 쎄럼스 앤드 백신스 리미티드 항미생물 방부 효능을 갖는 정맥 내 투여를 위한 안정한에멀젼 조성물
AU2006310044A1 (en) * 2005-08-12 2007-05-10 Bharat Serums & Vaccines Ltd. Aqueous anaesthetic compositions comprising propofol
WO2007128866A2 (en) * 2006-05-09 2007-11-15 Novobion Oy Novel chemical compositions
TWI498395B (zh) * 2008-03-11 2015-09-01 3M Innovative Properties Co 硬塗層組合物
WO2010148288A2 (en) * 2009-06-19 2010-12-23 Lyotropic Therapeutics, Inc. Pharmaceutical formulations with low aqueous levels of free unbound drug
EP2456823A4 (en) 2009-07-21 2012-12-26 3M Innovative Properties Co CURABLE COMPOSITION, METHOD FOR COATING A PHOTO TOOL, AND COATED PHOTO TOOL
WO2011034845A1 (en) 2009-09-16 2011-03-24 3M Innovative Properties Company Fluorinated coating and phototools made therewith
EP2478033A1 (en) 2009-09-16 2012-07-25 3M Innovative Properties Company Fluorinated coating and phototools made therewith
US8268067B2 (en) * 2009-10-06 2012-09-18 3M Innovative Properties Company Perfluoropolyether coating composition for hard surfaces
EP2345427A1 (de) * 2010-01-14 2011-07-20 SapioTec GmbH Flurankomplex
DK2484350T3 (en) * 2011-02-04 2016-08-01 Norbert Univ -Prof Dr Med Roewer A pharmaceutical composition containing a complex of a cyclodextrin with a propofolsalt
CN103998046B (zh) * 2011-11-29 2021-04-06 优奥斯私人有限公司 包含环糊精和疏水性药物的可注射药物组合物的防腐方法
AU2013273764B2 (en) * 2011-11-29 2016-05-05 Zoetis Services Llc Pharmaceutical compositions
CN103263404B (zh) * 2012-04-28 2017-12-01 中国人民解放军军事医学科学院放射与辐射医学研究所 一种复合麻醉药物
IL294306B2 (en) 2012-08-21 2024-01-01 Sage Therapeutics Inc Methods of treating epilepsy or status epilepticus
WO2017132243A1 (en) * 2016-01-29 2017-08-03 Cuda Anesthetics, Llc Aqueous pharmaceutical formulation comprising propofol
FR3117337B1 (fr) 2020-12-10 2023-04-28 Centre Hospitalier Univ De Lille Composition pharmaceutique contenant du propofol, une cyclodextrine ou un dérivé de cyclodextrine et un sel pharmaceuticalement acceptable

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA962214B (en) * 1995-04-10 1996-10-07 Farmarc Nederland Bv Pharmaceutical composition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
IJP vol.139, pp.215-218 (1996)
Pharmaceutical Research vol.16, pp.562-568 (1999)

Also Published As

Publication number Publication date
HUP0301646A3 (en) 2005-06-28
CN1454085A (zh) 2003-11-05
EP1299095A1 (en) 2003-04-09
ATE267592T1 (de) 2004-06-15
CN1254237C (zh) 2006-05-03
MXPA02012611A (es) 2004-07-30
NO20025999L (no) 2002-12-13
NZ523643A (en) 2004-05-28
BR0017268A (pt) 2003-05-27
JP2003535893A (ja) 2003-12-02
PL359624A1 (en) 2004-08-23
AP2002002674A0 (en) 2002-12-31
IN187686B (cg-RX-API-DMAC10.html) 2002-06-08
NO20025999D0 (no) 2002-12-13
BG107463A (en) 2003-11-28
CA2414064C (en) 2013-01-08
PT1299095E (pt) 2004-10-29
EP1299095B1 (en) 2004-05-26
DK1299095T3 (da) 2004-10-11
AU2001235972B2 (en) 2005-07-21
JP4907833B2 (ja) 2012-04-04
YU2703A (sh) 2006-03-03
IL153387A0 (en) 2003-07-06
US20040014718A1 (en) 2004-01-22
EA005589B1 (ru) 2005-04-28
ZA200300336B (en) 2004-04-08
DE60011149T2 (de) 2005-07-07
CA2414064A1 (en) 2001-12-27
AU3597201A (en) 2002-01-02
DE60011149D1 (de) 2004-07-01
KR20030023875A (ko) 2003-03-20
WO2001097796A1 (en) 2001-12-27
HUP0301646A2 (hu) 2003-09-29
EA200300047A1 (ru) 2003-06-26
US7138387B2 (en) 2006-11-21
ES2222271T3 (es) 2005-02-01

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