KR100806978B1 - 1,5-이치환된-3,4-디히드로-1ｈ-피리미도[4,5-ｄ]피리미딘-2-온 화합물 및 ｃｓｂｐ/ｐ38 키나제 매개된 질환의치료시 이들의 용도 - Google Patents

1,5-이치환된-3,4-디히드로-1ｈ-피리미도[4,5-ｄ]피리미딘-2-온 화합물 및 ｃｓｂｐ/ｐ38 키나제 매개된 질환의치료시 이들의 용도 Download PDF

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KR100806978B1
KR100806978B1 KR1020027011408A KR20027011408A KR100806978B1 KR 100806978 B1 KR100806978 B1 KR 100806978B1 KR 1020027011408 A KR1020027011408 A KR 1020027011408A KR 20027011408 A KR20027011408 A KR 20027011408A KR 100806978 B1 KR100806978 B1 KR 100806978B1
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alkyl
dihydro
pyrimido
aryl
pyrimidin
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KR20020082858A (ko
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제리 엘. 아담스
제프리 씨. 보엠
랄프 에프. 홀
존 제이. 타가트
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스미스클라인 비참 코포레이션
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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KR1020027011408A 2000-03-02 2001-03-02 1,5-이치환된-3,4-디히드로-1ｈ-피리미도[4,5-ｄ]피리미딘-2-온 화합물 및 ｃｓｂｐ/ｐ38 키나제 매개된 질환의치료시 이들의 용도 Expired - Fee Related KR100806978B1 (ko)

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US18641900P 2000-03-02 2000-03-02
US60/186,419 2000-03-02

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KR20020082858A KR20020082858A (ko) 2002-10-31
KR100806978B1 true KR100806978B1 (ko) 2008-02-25

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AR (2) AR030053A1 (https=)
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JP2009542817A (ja) * 2006-06-16 2009-12-03 グラクソ グループ リミテッド 新規化合物
KR101040394B1 (ko) * 2010-05-18 2011-06-09 (주)이성산업 역화 방지 기능을 갖는 야외용 가스 히터
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AU2001239992B2 (en) 2005-09-01
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NO20024134L (no) 2002-10-24
ZA200207017B (en) 2004-02-26
IL189865A0 (en) 2008-08-07
AR030053A1 (es) 2003-08-13
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JP2003525295A (ja) 2003-08-26
CA2402092C (en) 2012-01-24
EP1265900A1 (en) 2002-12-18
MXPA02008588A (es) 2003-02-24
DE60128457D1 (de) 2007-06-28
NZ520914A (en) 2004-03-26
EP1265900B1 (en) 2007-05-16
ATE362473T1 (de) 2007-06-15
IL151426A (en) 2011-01-31
CZ20022933A3 (cs) 2003-02-12
BR0108715A (pt) 2004-04-27
MY141144A (en) 2010-03-15
CN100482664C (zh) 2009-04-29
NO326409B1 (no) 2008-12-01
IL151426A0 (en) 2003-04-10
EP1265900A4 (en) 2004-11-10
NO20024134D0 (no) 2002-08-30
HUP0204431A1 (hu) 2003-04-28
DE60128457T2 (de) 2008-01-17
TWI290926B (en) 2007-12-11
CY1106816T1 (el) 2012-01-25
AU3999201A (en) 2001-09-12
WO2001064679A1 (en) 2001-09-07

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