KR100771281B1 - 포르모테롤을 포함하는 에어로졸 조성물 - Google Patents

포르모테롤을 포함하는 에어로졸 조성물 Download PDF

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Publication number
KR100771281B1
KR100771281B1 KR1020027006847A KR20027006847A KR100771281B1 KR 100771281 B1 KR100771281 B1 KR 100771281B1 KR 1020027006847 A KR1020027006847 A KR 1020027006847A KR 20027006847 A KR20027006847 A KR 20027006847A KR 100771281 B1 KR100771281 B1 KR 100771281B1
Authority
KR
South Korea
Prior art keywords
formoterol
dry powder
carrier
diluent
inhalable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020027006847A
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English (en)
Korean (ko)
Other versions
KR20020058050A (ko
Inventor
바바라 하에베를린
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10865451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100771281(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20020058050A publication Critical patent/KR20020058050A/ko
Application granted granted Critical
Publication of KR100771281B1 publication Critical patent/KR100771281B1/ko
Assigned to 산도즈 아게 reassignment 산도즈 아게 권리의 전부이전등록 Assignors: 노파르티스 아게
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020027006847A 1999-11-30 2000-11-28 포르모테롤을 포함하는 에어로졸 조성물 Expired - Fee Related KR100771281B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9928311.1 1999-11-30
GBGB9928311.1A GB9928311D0 (en) 1999-11-30 1999-11-30 Organic compounds

Publications (2)

Publication Number Publication Date
KR20020058050A KR20020058050A (ko) 2002-07-12
KR100771281B1 true KR100771281B1 (ko) 2007-10-29

Family

ID=10865451

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027006847A Expired - Fee Related KR100771281B1 (ko) 1999-11-30 2000-11-28 포르모테롤을 포함하는 에어로졸 조성물

Country Status (24)

Country Link
US (3) US6887459B1 (https=)
EP (3) EP3050558A1 (https=)
JP (3) JP2003515551A (https=)
KR (1) KR100771281B1 (https=)
CN (1) CN1399540A (https=)
AU (1) AU769765B2 (https=)
BR (1) BR0015908A (https=)
CA (1) CA2389349C (https=)
CZ (1) CZ20021850A3 (https=)
ES (1) ES2178943B1 (https=)
FR (1) FR2801506B1 (https=)
GB (1) GB9928311D0 (https=)
HU (1) HUP0203728A3 (https=)
IL (2) IL149362A0 (https=)
IT (1) ITMI20002556A1 (https=)
MX (1) MXPA02005384A (https=)
NO (1) NO20021963D0 (https=)
NZ (1) NZ518873A (https=)
PL (1) PL354974A1 (https=)
RU (1) RU2327452C2 (https=)
SK (1) SK7432002A3 (https=)
TW (1) TWI278324B (https=)
WO (1) WO2001039745A2 (https=)
ZA (1) ZA200204147B (https=)

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GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
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ES2342463T3 (es) * 2002-03-01 2010-07-07 Chiesi Farmaceutici S.P.A. Formulacion superfina de formoterol.
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US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
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PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
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US20100055045A1 (en) 2008-02-26 2010-03-04 William Gerhart Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
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CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
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Also Published As

Publication number Publication date
WO2001039745A3 (en) 2001-12-20
BR0015908A (pt) 2002-08-06
ES2178943A1 (es) 2003-01-01
ES2178943B1 (es) 2004-03-16
IL149362A (en) 2015-06-30
RU2002116251A (ru) 2004-01-20
EP2011484A3 (en) 2009-01-14
US20050136010A1 (en) 2005-06-23
NO20021963L (no) 2002-04-25
KR20020058050A (ko) 2002-07-12
CZ20021850A3 (cs) 2002-08-14
CN1399540A (zh) 2003-02-26
EP1233757A2 (en) 2002-08-28
CA2389349C (en) 2009-10-20
US20070196286A1 (en) 2007-08-23
GB9928311D0 (en) 2000-01-26
AU769765B2 (en) 2004-02-05
MXPA02005384A (es) 2002-11-29
FR2801506A1 (fr) 2001-06-01
TWI278324B (en) 2007-04-11
PL354974A1 (en) 2004-03-22
RU2327452C2 (ru) 2008-06-27
JP2013075909A (ja) 2013-04-25
JP2015108020A (ja) 2015-06-11
HUP0203728A3 (en) 2003-12-29
EP3050558A1 (en) 2016-08-03
US6887459B1 (en) 2005-05-03
AU2837401A (en) 2001-06-12
JP2003515551A (ja) 2003-05-07
ITMI20002556A1 (it) 2002-05-28
FR2801506B1 (fr) 2002-12-27
CA2389349A1 (en) 2001-06-07
NO20021963D0 (no) 2002-04-25
IL149362A0 (en) 2002-11-10
SK7432002A3 (en) 2002-10-08
EP2011484A2 (en) 2009-01-07
HUP0203728A2 (hu) 2003-03-28
WO2001039745A2 (en) 2001-06-07
ZA200204147B (en) 2003-01-29
NZ518873A (en) 2004-02-27

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