CN1399540A - 包含福莫特罗的气雾剂组合物 - Google Patents

包含福莫特罗的气雾剂组合物 Download PDF

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Publication number
CN1399540A
CN1399540A CN00816245A CN00816245A CN1399540A CN 1399540 A CN1399540 A CN 1399540A CN 00816245 A CN00816245 A CN 00816245A CN 00816245 A CN00816245 A CN 00816245A CN 1399540 A CN1399540 A CN 1399540A
Authority
CN
China
Prior art keywords
dry powder
formoterol
carrier
diluent
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00816245A
Other languages
English (en)
Chinese (zh)
Inventor
B·翰贝尔林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10865451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1399540(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1399540A publication Critical patent/CN1399540A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00816245A 1999-11-30 2000-11-28 包含福莫特罗的气雾剂组合物 Pending CN1399540A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9928311.1 1999-11-30
GBGB9928311.1A GB9928311D0 (en) 1999-11-30 1999-11-30 Organic compounds

Publications (1)

Publication Number Publication Date
CN1399540A true CN1399540A (zh) 2003-02-26

Family

ID=10865451

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00816245A Pending CN1399540A (zh) 1999-11-30 2000-11-28 包含福莫特罗的气雾剂组合物

Country Status (24)

Country Link
US (3) US6887459B1 (https=)
EP (3) EP3050558A1 (https=)
JP (3) JP2003515551A (https=)
KR (1) KR100771281B1 (https=)
CN (1) CN1399540A (https=)
AU (1) AU769765B2 (https=)
BR (1) BR0015908A (https=)
CA (1) CA2389349C (https=)
CZ (1) CZ20021850A3 (https=)
ES (1) ES2178943B1 (https=)
FR (1) FR2801506B1 (https=)
GB (1) GB9928311D0 (https=)
HU (1) HUP0203728A3 (https=)
IL (2) IL149362A0 (https=)
IT (1) ITMI20002556A1 (https=)
MX (1) MXPA02005384A (https=)
NO (1) NO20021963D0 (https=)
NZ (1) NZ518873A (https=)
PL (1) PL354974A1 (https=)
RU (1) RU2327452C2 (https=)
SK (1) SK7432002A3 (https=)
TW (1) TWI278324B (https=)
WO (1) WO2001039745A2 (https=)
ZA (1) ZA200204147B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101342155B (zh) * 2007-07-11 2012-01-04 天津帝士力投资控股集团有限公司 一种(r,r)-福莫特罗吸入粉雾剂及其制备方法
CN103347501A (zh) * 2011-02-04 2013-10-09 诺华股份有限公司 用于治疗阻塞性或炎性呼吸道疾病的包含二或多种活性成分的颗粒的干粉制剂

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GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
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ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
ES2245612B1 (es) * 2004-06-29 2007-08-16 Universidad De Barcelona Nuevo uso terapeutico del formoterol.
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
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CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
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CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101342155B (zh) * 2007-07-11 2012-01-04 天津帝士力投资控股集团有限公司 一种(r,r)-福莫特罗吸入粉雾剂及其制备方法
CN103347501A (zh) * 2011-02-04 2013-10-09 诺华股份有限公司 用于治疗阻塞性或炎性呼吸道疾病的包含二或多种活性成分的颗粒的干粉制剂
CN103347501B (zh) * 2011-02-04 2015-11-25 诺华股份有限公司 用于治疗阻塞性或炎性呼吸道疾病的包含二或多种活性成分的颗粒的干粉制剂

Also Published As

Publication number Publication date
WO2001039745A3 (en) 2001-12-20
BR0015908A (pt) 2002-08-06
ES2178943A1 (es) 2003-01-01
ES2178943B1 (es) 2004-03-16
IL149362A (en) 2015-06-30
KR100771281B1 (ko) 2007-10-29
RU2002116251A (ru) 2004-01-20
EP2011484A3 (en) 2009-01-14
US20050136010A1 (en) 2005-06-23
NO20021963L (no) 2002-04-25
KR20020058050A (ko) 2002-07-12
CZ20021850A3 (cs) 2002-08-14
EP1233757A2 (en) 2002-08-28
CA2389349C (en) 2009-10-20
US20070196286A1 (en) 2007-08-23
GB9928311D0 (en) 2000-01-26
AU769765B2 (en) 2004-02-05
MXPA02005384A (es) 2002-11-29
FR2801506A1 (fr) 2001-06-01
TWI278324B (en) 2007-04-11
PL354974A1 (en) 2004-03-22
RU2327452C2 (ru) 2008-06-27
JP2013075909A (ja) 2013-04-25
JP2015108020A (ja) 2015-06-11
HUP0203728A3 (en) 2003-12-29
EP3050558A1 (en) 2016-08-03
US6887459B1 (en) 2005-05-03
AU2837401A (en) 2001-06-12
JP2003515551A (ja) 2003-05-07
ITMI20002556A1 (it) 2002-05-28
FR2801506B1 (fr) 2002-12-27
CA2389349A1 (en) 2001-06-07
NO20021963D0 (no) 2002-04-25
IL149362A0 (en) 2002-11-10
SK7432002A3 (en) 2002-10-08
EP2011484A2 (en) 2009-01-07
HUP0203728A2 (hu) 2003-03-28
WO2001039745A2 (en) 2001-06-07
ZA200204147B (en) 2003-01-29
NZ518873A (en) 2004-02-27

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