KR100761329B1 - 피부노화 방지 및 주름 생성 억제 효과를 나타내는장생도라지 추출물 및 이로부터 분리된 정제 분획물들을함유하는 피부외용 조성물 - Google Patents
피부노화 방지 및 주름 생성 억제 효과를 나타내는장생도라지 추출물 및 이로부터 분리된 정제 분획물들을함유하는 피부외용 조성물 Download PDFInfo
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- KR100761329B1 KR100761329B1 KR1020060038664A KR20060038664A KR100761329B1 KR 100761329 B1 KR100761329 B1 KR 100761329B1 KR 1020060038664 A KR1020060038664 A KR 1020060038664A KR 20060038664 A KR20060038664 A KR 20060038664A KR 100761329 B1 KR100761329 B1 KR 100761329B1
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Abstract
Description
번호 | 원 료 | 함량(중량%) |
1 | 실시예 1의 장생도라지 추출물 | 0.5 |
2 | 부틸렌 글리콜 | 4.0 |
3 | 글리세린 | 8.0 |
4 | 카르복시비닐폴리머 | 0.06 |
5 | 디소디움 에틸렌디아민테르라아세틱에시드 | 0.01 |
6 | 에탄올 | 7.0 |
7 | 트리에탄올아민 | 0.2 |
8 | 소르비탄모노스테아레이트 | 0.8 |
9 | 하이드로지네이티드 캐스터 오일 | 0.4 |
10 | 페닐트리메티콘 | 3.5 |
11 | 파라옥시안식향산프로필 | 0.2 |
12 | 파라옥시안식향산메틸 | 0.2 |
13 | 정제수 | 잔량 |
계 | 100.0 |
번호 | 원 료 | 함량(중량%) |
1 | 실시예 2의 CKO | 0.5 |
2 | 스테아린산 | 1.0 |
3 | 세틸알코올 | 1.0 |
4 | 글리세릴모노스테아레이트 | 1.0 |
5 | 폴리옥시에틸렌소르비탄모노스테아레이트 | 1.0 |
6 | 솔비탄세스퀴올레이트 | 1.0 |
7 | 유동파라핀 | 4.0 |
8 | 카르릴릭/카프릭트리글리세라이드 | 4.0 |
9 | 스쿠알란 | 3.0 |
10 | 카르복시비닐폴리머 | 0.1 |
11 | 부틸렌글리콜 | 5.0 |
12 | 트리에탄올아민 | 0.2 |
13 | 파라옥시안식향산프로필 | 0.2 |
14 | 파라옥시안식향산메틸 | 0.2 |
15 | 정제수 | 잔량 |
계 | 100.0 |
번호 | 원 료 | 함량(중량%) |
1 | 실시예 1의 CKI | 0.5 |
2 | 스테아린산 | 2.0 |
3 | 세틸알코올 | 2.0 |
4 | 글리세릴모노스테아레이트 | 2.0 |
5 | 폴리옥시에틸렌소르비탄모노스테아레이트 | 0.5 |
6 | 솔비탄세스퀴올레이트 | 0.5 |
7 | 글리세릴모노스테아레이트/글리세릴스테아레이트/폴리옥시에틸렌스테아레이트 | 1.0 |
8 | 왁스 | 1.0 |
9 | 유동파라핀 | 4.0 |
10 | 카르릴릭/카프릭트리글리세라이드 | 4.0 |
11 | 스쿠알란 | 4.0 |
12 | 카르복시비닐폴리머 | 0.3 |
13 | 부틸렌글리콜 | 5.0 |
14 | 글리세린 | 3.0 |
15 | 트리에탄올아민 | 0.5 |
16 | 파라옥시안식향산프로필 | 0.2 |
17 | 파라옥시안식향산메틸 | 0.2 |
18 | 정제수 | 잔량 |
계 | 100.0 |
번호 | 원 료 | 함량(중량%) |
1 | 실시예 1의 CKS | 0.5 |
2 | 시토 스테롤 | 1.70 |
3 | 폴리글리세릴 2-올레이트 | 1.50 |
4 | 세라마이드 | 0.7 |
5 | 세테아레스-4 | 1.2 |
6 | 콜레스테롤 | 1.5 |
7 | 디세틸포스페이트 | 0.4 |
8 | 농글리세린 | 5.0 |
9 | 선플라우어오일 | 15.0 |
10 | 카르복시비닐폴리머 | 0.2 |
11 | 산탄검 | 0.2 |
12 | 방부제 | 미량 |
13 | 향료 | 미량 |
14 | 정제수 | 잔량 |
계 | 100.0 |
Claims (7)
- 20년 근 이상의 도라지인 장생도라지를 건조, 분쇄한 후, 물을 추출용매로 하여 90 내지 95℃에서 열수추출법으로 추출한 후 수득한 (1) 장생도라지 조추출물; 상기 조추출물을 물에 녹여 여과한 여과액을 이온교환수지인 HP-20컬럼에 통과시켜, 당성분을 제거한 후, 컬럼에 흡착되어 남은 유기물 성분을 다시 메탄올 용액으로 탈착시켜, 물 또는 메탄올 가용 분획물을 각각 제조한 후, 물 가용 분획물로부터 얻은 (2) 이눌린 정제 분획물 및 (3) 올리고당 정제 분획물; 또는 메탄올 가용 분획물에 에틸에테르를 가하여 침전된 침전물로부터 얻은 사포닌 성분이 다량 함유된 (4) 조사포닌 정제 분획물을 유효성분으로 함유하는 피부노화 방지 및 주름개선용 피부외용 약학 조성물.
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- 20년 근 이상의 도라지인 장생도라지를 건조, 분쇄한 후, 물을 추출용매로 하여 90 내지 95℃에서 열수추출법으로 추출한 후 수득한 (1) 장생도라지 조추출물; 상기 조추출물을 물에 녹여 여과한 여과액을 이온교환수지인 HP-20컬럼에 통과시켜, 당성분을 제거한 후, 컬럼에 흡착되어 남은 유기물 성분을 다시 메탄올 용액으로 탈착시켜, 물 또는 메탄올 가용 분획물을 각각 제조한 후, 물 가용 분획물로부터 얻은 (2) 이눌린 정제 분획물 및 (3) 올리고당 정제 분획물; 또는 메탄올 가용 분획물에 에틸에테르를 가하여 침전된 침전물로부터 얻은 사포닌 성분이 다량 함유된 (4) 조사포닌 정제 분획물을 유효성분으로 함유하는 피부노화 방지 및 주름개선용 화장료 조성물.
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Cited By (3)
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KR100901519B1 (ko) | 2007-12-07 | 2009-06-08 | 바이오스펙트럼 주식회사 | 플라티코딘-디를 함유하는 피부미백제 |
KR101188775B1 (ko) | 2010-10-13 | 2012-10-10 | 충남대학교산학협력단 | 장생도라지 유래의 조사포닌 분획물을 함유하는 골다공증 예방 및 치료용 조성물 |
WO2016153262A3 (en) * | 2015-03-26 | 2017-03-23 | B&C Biopharm Co., Ltd. | Pharmaceutical composition comprising the extract of platycodon grandiflorum enhanced effective saponin contents for treatment of rheumatoid arthritis |
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KR20040008871A (ko) * | 2002-07-19 | 2004-01-31 | (주) 김형민한약연구소 | 피부보호 및 피부질환 개선용 조성물 및 그 제조방법 |
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JP2000198712A (ja) * | 1999-01-06 | 2000-07-18 | Rashieru Seiyaku Kk | 化粧料組成物 |
JP2001122730A (ja) * | 1999-10-26 | 2001-05-08 | Ichimaru Pharcos Co Ltd | 保湿性植物抽出物を含有する化粧料組成物 |
KR20030017963A (ko) * | 2001-10-29 | 2003-03-04 | 주식회사 나우코스 | 피부 탄력 증가와 피부노화 억제 효과를 갖는 원지, 길경,병풀을 함유한 화장료 조성물 및 그 추출물 제조 방법 |
KR20040008871A (ko) * | 2002-07-19 | 2004-01-31 | (주) 김형민한약연구소 | 피부보호 및 피부질환 개선용 조성물 및 그 제조방법 |
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KR100901519B1 (ko) | 2007-12-07 | 2009-06-08 | 바이오스펙트럼 주식회사 | 플라티코딘-디를 함유하는 피부미백제 |
KR101188775B1 (ko) | 2010-10-13 | 2012-10-10 | 충남대학교산학협력단 | 장생도라지 유래의 조사포닌 분획물을 함유하는 골다공증 예방 및 치료용 조성물 |
WO2016153262A3 (en) * | 2015-03-26 | 2017-03-23 | B&C Biopharm Co., Ltd. | Pharmaceutical composition comprising the extract of platycodon grandiflorum enhanced effective saponin contents for treatment of rheumatoid arthritis |
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