KR100706566B1 - 5환성 탁산 화합물 - Google Patents

5환성 탁산 화합물 Download PDF

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Publication number
KR100706566B1
KR100706566B1 KR1020027004826A KR20027004826A KR100706566B1 KR 100706566 B1 KR100706566 B1 KR 100706566B1 KR 1020027004826 A KR1020027004826 A KR 1020027004826A KR 20027004826 A KR20027004826 A KR 20027004826A KR 100706566 B1 KR100706566 B1 KR 100706566B1
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KR
South Korea
Prior art keywords
group
compound
formula
compounds
compound according
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KR1020027004826A
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English (en)
Korean (ko)
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KR20020035901A (ko
Inventor
소가쓰네히코
우오토고우이치
다케다야스유키
Original Assignee
다이이찌 세이야꾸 가부시기가이샤
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Publication of KR20020035901A publication Critical patent/KR20020035901A/ko
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Publication of KR100706566B1 publication Critical patent/KR100706566B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
KR1020027004826A 1999-10-15 2000-10-12 5환성 탁산 화합물 KR100706566B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29335699 1999-10-15
JPJP-P-1999-00293356 1999-10-15

Publications (2)

Publication Number Publication Date
KR20020035901A KR20020035901A (ko) 2002-05-15
KR100706566B1 true KR100706566B1 (ko) 2007-04-13

Family

ID=17793741

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027004826A KR100706566B1 (ko) 1999-10-15 2000-10-12 5환성 탁산 화합물

Country Status (22)

Country Link
EP (1) EP1221445B1 (fr)
JP (1) JP3776799B2 (fr)
KR (1) KR100706566B1 (fr)
CN (1) CN1203074C (fr)
AR (1) AR026026A1 (fr)
AT (1) ATE405569T1 (fr)
AU (1) AU774787B2 (fr)
BR (1) BR0014687A (fr)
CA (1) CA2386772C (fr)
DE (1) DE60039998D1 (fr)
DK (1) DK1221445T3 (fr)
ES (1) ES2311473T3 (fr)
HK (1) HK1044000B (fr)
IL (2) IL149007A0 (fr)
MX (1) MXPA02003797A (fr)
MY (1) MY125378A (fr)
NO (1) NO328418B1 (fr)
PT (1) PT1221445E (fr)
RU (1) RU2257387C2 (fr)
TW (1) TWI225062B (fr)
WO (1) WO2001027115A1 (fr)
ZA (1) ZA200202696B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1457492B1 (fr) * 2001-11-29 2008-01-02 Daiichi Sankyo Company, Limited Cristaux de derive de taxane et procede de production associe
TW200533339A (en) 2004-03-16 2005-10-16 Bristol Myers Squibb Co Therapeutic synergy of anti-cancer compounds
WO2005105807A1 (fr) 2004-04-30 2005-11-10 Daiichi Pharmaceutical Co., Ltd. Processus de production de taxane pentacylique
WO2007049575A1 (fr) * 2005-10-25 2007-05-03 Daiichi Sankyo Company, Limited Composé du taxane ayant une structure cyclique d'azétidine
CN100516067C (zh) * 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US8785669B2 (en) * 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
WO2013018829A1 (fr) 2011-08-02 2013-02-07 アステラス製薬株式会社 Procédé de traitement du cancer par une utilisation combinée d'agents médicinaux
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995013270A1 (fr) * 1993-11-08 1995-05-18 Rhone-Poulenc Rorer S.A. Nouveaux derives de taxicine, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0916348A1 (fr) * 1996-06-06 1999-05-19 Daiichi Pharmaceutical Co., Ltd. Complexes medicamenteux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW480262B (en) * 1995-04-28 2002-03-21 Daiichi Seiyaku Co A taxol derivative having an antitumor activity and a pharmaceutical composition comprising the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995013270A1 (fr) * 1993-11-08 1995-05-18 Rhone-Poulenc Rorer S.A. Nouveaux derives de taxicine, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0916348A1 (fr) * 1996-06-06 1999-05-19 Daiichi Pharmaceutical Co., Ltd. Complexes medicamenteux

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EP 916348 A1. *
Tetrahedron, Vol.53. No.37, pp.12575-12594, 1997.
WO 95/13270 A1.

Also Published As

Publication number Publication date
CA2386772A1 (fr) 2001-04-19
AR026026A1 (es) 2002-12-26
PT1221445E (pt) 2008-10-08
AU774787B2 (en) 2004-07-08
ATE405569T1 (de) 2008-09-15
ES2311473T3 (es) 2009-02-16
MXPA02003797A (es) 2002-12-13
DK1221445T3 (da) 2008-11-24
EP1221445B1 (fr) 2008-08-20
HK1044000A1 (en) 2002-10-04
IL149007A (en) 2006-12-10
CN1409714A (zh) 2003-04-09
JP3776799B2 (ja) 2006-05-17
EP1221445A1 (fr) 2002-07-10
EP1221445A4 (fr) 2003-05-28
RU2257387C2 (ru) 2005-07-27
ZA200202696B (en) 2003-09-23
DE60039998D1 (de) 2008-10-02
NO20021753D0 (no) 2002-04-12
CA2386772C (fr) 2009-01-13
TWI225062B (en) 2004-12-11
AU7685100A (en) 2001-04-23
WO2001027115A1 (fr) 2001-04-19
NO328418B1 (no) 2010-02-15
NO20021753L (no) 2002-06-12
BR0014687A (pt) 2002-11-19
MY125378A (en) 2006-07-31
HK1044000B (zh) 2008-11-21
CN1203074C (zh) 2005-05-25
KR20020035901A (ko) 2002-05-15
IL149007A0 (en) 2002-11-10

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