KR100591652B1 - ＩｇＥ의 억제제로서의 벤즈이미다졸 유사체 - Google Patents

ＩｇＥ의 억제제로서의 벤즈이미다졸 유사체 Download PDF

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Publication number
KR100591652B1
KR100591652B1 KR1020007013141A KR20007013141A KR100591652B1 KR 100591652 B1 KR100591652 B1 KR 100591652B1 KR 1020007013141 A KR1020007013141 A KR 1020007013141A KR 20007013141 A KR20007013141 A KR 20007013141A KR 100591652 B1 KR100591652 B1 KR 100591652B1
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South Korea
Prior art keywords
benzimidazole
ige
aminophenyl
mmol
substituted
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Expired - Fee Related
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KR1020007013141A
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English (en)
Korean (ko)
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KR20010030179A (ko
Inventor
자가디쉬 서카르
마크 엘. 리처즈
마이클 지. 캠벨
마이클 더블유. 메이저
Original Assignee
아바니르 파마슈티컬스
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Application filed by 아바니르 파마슈티컬스 filed Critical 아바니르 파마슈티컬스
Publication of KR20010030179A publication Critical patent/KR20010030179A/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Amplifiers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1020007013141A 1998-05-22 1999-05-21 ＩｇＥ의 억제제로서의 벤즈이미다졸 유사체 Expired - Fee Related KR100591652B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8649498P 1998-05-22 1998-05-22
US60/086,494 1998-05-22

Publications (2)

Publication Number Publication Date
KR20010030179A KR20010030179A (ko) 2001-04-16
KR100591652B1 true KR100591652B1 (ko) 2006-06-26

Family

ID=22198947

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007013141A Expired - Fee Related KR100591652B1 (ko) 1998-05-22 1999-05-21 ＩｇＥ의 억제제로서의 벤즈이미다졸 유사체

Country Status (22)

Country Link
US (2) US6271390B1 (https=)
EP (3) EP1079830A1 (https=)
JP (3) JP2002516277A (https=)
KR (1) KR100591652B1 (https=)
CN (4) CN1311675A (https=)
AT (1) ATE292465T1 (https=)
AU (3) AU754562B2 (https=)
BR (3) BR9910642A (https=)
CA (3) CA2332985A1 (https=)
CZ (2) CZ20004351A3 (https=)
DE (1) DE69924607T2 (https=)
ES (1) ES2241285T3 (https=)
HU (3) HUP0102128A3 (https=)
IL (3) IL139828A0 (https=)
MX (3) MXPA00011422A (https=)
NO (3) NO20005889L (https=)
NZ (2) NZ508416A (https=)
PL (3) PL345560A1 (https=)
RU (2) RU2236221C2 (https=)
UA (2) UA67775C2 (https=)
WO (3) WO1999061020A1 (https=)
ZA (3) ZA200007754B (https=)

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WO2010045633A3 (en) * 2008-10-17 2010-07-15 National Jewish Health Measurement and analysis of leukotrienes

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CA2332989A1 (en) 1999-12-02
HUP0101894A2 (hu) 2002-02-28
PL345219A1 (en) 2001-12-03
JP2002516274A (ja) 2002-06-04
RU2236220C2 (ru) 2004-09-20
ZA200007752B (en) 2001-12-05
NZ508413A (en) 2003-08-29
US6451829B2 (en) 2002-09-17
NO20005889L (no) 2001-01-22
HUP0101894A3 (en) 2002-07-29
HUP0102550A3 (en) 2002-11-28
EP1077700A1 (en) 2001-02-28
CA2332985A1 (en) 1999-12-02
KR20010030179A (ko) 2001-04-16
MXPA00011470A (es) 2002-10-17
NO20005887L (no) 2001-01-19
BR9910640A (pt) 2001-10-30
AU4197899A (en) 1999-12-13
HUP0102128A2 (hu) 2002-03-28
MXPA00011422A (es) 2002-12-13
AU4312099A (en) 1999-12-13
IL139828A0 (en) 2002-02-10
CN1721411A (zh) 2006-01-18
CZ20004350A3 (cs) 2002-02-13
NO20005888D0 (no) 2000-11-21
HUP0102128A3 (en) 2002-05-28
WO1999061020A1 (en) 1999-12-02
AU754562B2 (en) 2002-11-21
EP1079830A1 (en) 2001-03-07
ATE292465T1 (de) 2005-04-15
JP2002516276A (ja) 2002-06-04
PL345560A1 (en) 2001-12-17
CN1219510C (zh) 2005-09-21
CN1317965A (zh) 2001-10-17
DE69924607D1 (de) 2005-05-12
ZA200007753B (en) 2001-07-18
UA67775C2 (uk) 2004-07-15
PL345952A1 (en) 2002-01-14
ES2241285T3 (es) 2005-10-16
JP2002516277A (ja) 2002-06-04
BR9910641A (pt) 2001-10-02
CN1311679A (zh) 2001-09-05
IL139827A0 (en) 2002-02-10
ZA200007754B (en) 2001-08-16
EP1077700B1 (en) 2005-04-06
HUP0102550A2 (hu) 2001-10-28
NO20005887D0 (no) 2000-11-21
UA67774C2 (uk) 2004-07-15
DE69924607T2 (de) 2006-02-02
AU4094299A (en) 1999-12-13
WO1999061013A3 (en) 2000-04-06
AU754943B2 (en) 2002-11-28
MXPA00011467A (es) 2002-10-17
NO20005888L (no) 2001-01-22
CA2332999A1 (en) 1999-12-02
BR9910642A (pt) 2001-10-09
NO20005889D0 (no) 2000-11-21
NZ508416A (en) 2004-01-30
IL139826A0 (en) 2002-02-10
CZ20004351A3 (cs) 2001-10-17
CN1311675A (zh) 2001-09-05
US6271390B1 (en) 2001-08-07
EP1077695A2 (en) 2001-02-28
WO1999061019A1 (en) 1999-12-02
US20020010343A1 (en) 2002-01-24
RU2236221C2 (ru) 2004-09-20
WO1999061013A2 (en) 1999-12-02

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