KR100577057B1 - 단위 제형 - Google Patents
단위 제형 Download PDFInfo
- Publication number
- KR100577057B1 KR100577057B1 KR1020017013747A KR20017013747A KR100577057B1 KR 100577057 B1 KR100577057 B1 KR 100577057B1 KR 1020017013747 A KR1020017013747 A KR 1020017013747A KR 20017013747 A KR20017013747 A KR 20017013747A KR 100577057 B1 KR100577057 B1 KR 100577057B1
- Authority
- KR
- South Korea
- Prior art keywords
- unit dosage
- dosage form
- compound
- pde5
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- WOXKDUGGOYFFRN-IIBYNOLFSA-N CN(CC(N([C@@H]1Cc2c3[nH]c4c2cccc4)[C@@H]3c(cc2)cc3c2OCO3)=O)C1=O Chemical compound CN(CC(N([C@@H]1Cc2c3[nH]c4c2cccc4)[C@@H]3c(cc2)cc3c2OCO3)=O)C1=O WOXKDUGGOYFFRN-IIBYNOLFSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Formation And Processing Of Food Products (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Glass Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13203699P | 1999-04-30 | 1999-04-30 | |
| US60/132,036 | 1999-04-30 | ||
| PCT/US2000/011129 WO2000066099A2 (en) | 1999-04-30 | 2000-04-26 | Compositions comprising phosphodiesterase inhabitors for the treatment of sexual disfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20020008396A KR20020008396A (ko) | 2002-01-30 |
| KR100577057B1 true KR100577057B1 (ko) | 2006-05-10 |
Family
ID=22452153
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020017013747A Ceased KR100577057B1 (ko) | 1999-04-30 | 2000-04-26 | 단위 제형 |
| KR1020000022108A Ceased KR20010020779A (ko) | 1999-04-30 | 2000-04-26 | 약학 제품 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020000022108A Ceased KR20010020779A (ko) | 1999-04-30 | 2000-04-26 | 약학 제품 |
Country Status (47)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150002453A (ko) | 2013-06-28 | 2015-01-07 | 한미약품 주식회사 | 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 저작정 제제 |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA004872B1 (ru) * | 1999-08-03 | 2004-08-26 | ЛИЛЛИ АЙКОС эЛ-эЛ-Си | β-КАРБОЛИНОВЫЕ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ |
| DE10010612A1 (de) * | 2000-03-03 | 2001-09-27 | Merck Patent Gmbh | Verwendung von PDE V-Inhibitoren |
| WO2001094347A1 (en) * | 2000-06-08 | 2001-12-13 | Lilly Icos Llc | Tetracyclic diketopiperazine compounds as pdev inhibitors |
| EP1305313A1 (en) * | 2000-08-02 | 2003-05-02 | Lilly Icos LLC | Fused heterocyclic derivatives as phosphodiesterase inhibitors |
| MXPA03011080A (es) * | 2001-06-05 | 2004-07-08 | Lilly Icos Llc | Compuestos tetraciclicos como inhibidores de pde5. |
| GB0129274D0 (en) * | 2001-12-06 | 2002-01-23 | Pfizer Ltd | Novel kit |
| US20060205733A1 (en) * | 2004-08-26 | 2006-09-14 | Encysive Pharmaceuticals | Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof |
| US8580954B2 (en) * | 2006-03-28 | 2013-11-12 | Hospira, Inc. | Formulations of low dose diclofenac and beta-cyclodextrin |
| US7495024B2 (en) | 2006-08-07 | 2009-02-24 | Via Pharmaceuticals, Inc. | Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque |
| DE102007028869A1 (de) | 2007-06-22 | 2008-12-24 | Ratiopharm Gmbh | Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil |
| DE102009033396A1 (de) | 2009-07-16 | 2011-01-20 | Ratiopharm Gmbh | Wässrige Lösung und gelatinierte Zusammensetzung umfassend einen Phosphodiesterase-5-Inhibitor sowie diesbezügliche Verfahren und Verwendung |
| US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110263606A1 (en) * | 2010-04-26 | 2011-10-27 | Horst Zerbe | Solid oral dosage forms comprising tadalafil |
| WO2012107092A1 (en) | 2011-02-10 | 2012-08-16 | Synthon Bv | Pharmaceutical composition comprising tadalafil and a cyclodextrin |
| RU2013141446A (ru) | 2011-02-10 | 2015-03-20 | Синтон Бв | Фармацевтическая композиция, содержащая тадалафил и циклодекстрин |
| EP2672959A1 (en) | 2011-02-10 | 2013-12-18 | Synthon BV | Granulated composition comprising tadalafil and a disintegrant |
| KR20150056443A (ko) | 2013-11-15 | 2015-05-26 | 한미약품 주식회사 | 타다라필 및 암로디핀을 포함하는 복합제제 |
| JP2019065006A (ja) | 2017-09-29 | 2019-04-25 | ハンミ ファーマシューティカルズ カンパニー リミテッド | 生産性及び均一性が改善されたタダラフィルを含む固形製剤、及びその製造方法 |
| EP3749370B1 (de) * | 2018-02-07 | 2025-05-07 | Smawa GmbH | Pharmazeutische formulierungen, verfahren zum herstellen einer pharmazeutischen formulierung sowie ein arzneimittel umfassend eine solche |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859006A (en) * | 1994-01-21 | 1999-01-12 | Icos Corporation | Tetracyclic derivatives; process of preparation and use |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
| GB9514465D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
| GB9423911D0 (en) * | 1994-11-26 | 1995-01-11 | Pfizer Ltd | Therapeutic agents |
| GB9511220D0 (en) * | 1995-06-02 | 1995-07-26 | Glaxo Group Ltd | Solid dispersions |
| GB9514464D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
| GB9514473D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
| ES2175404T3 (es) | 1996-05-10 | 2002-11-16 | Icos Corp | Derivados de carbolina. |
| EP0977756A1 (en) * | 1997-04-25 | 2000-02-09 | Pfizer Limited | PYRAZOLOPYRIMIDINONES WHICH INHIBIT TYPE 5 CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (cGMP PDE5) FOR THE TREATMENT OF SEXUAL DYSFUNCTION |
| AU4068599A (en) * | 1998-05-20 | 1999-12-06 | Schering Corporation | Combination of phentolamine and cyclic gmp phosphodiesterase inhibitors for the treatment of sexual dysfunction |
| AU1025899A (en) | 1998-09-16 | 2000-04-03 | Icos Corporation | Carboline derivatives as cgmp phosphodiesterase inhibitors |
| CA2346350C (en) * | 1998-10-05 | 2008-01-08 | Eisai Co., Ltd. | Intraoral quickly disintegrating tablets |
| WO2000053148A2 (en) * | 1999-03-08 | 2000-09-14 | Merck & Co., Inc. | Methods and compositions for treating erectile dysfunction |
| US6451807B1 (en) * | 1999-04-30 | 2002-09-17 | Lilly Icos, Llc. | Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor |
| CA2365782A1 (en) * | 1999-04-30 | 2000-11-09 | William E. Pullman | Treatment of female arousal disorder |
-
2000
- 2000-04-25 ES ES200001055A patent/ES2187234A1/es not_active Withdrawn
- 2000-04-25 HU HU0001632A patent/HUP0001632A3/hu unknown
- 2000-04-25 SV SV2000000055A patent/SV2002000055A/es not_active Application Discontinuation
- 2000-04-25 NO NO20002097A patent/NO20002097L/no not_active Application Discontinuation
- 2000-04-25 IL IL13581700A patent/IL135817A0/xx unknown
- 2000-04-25 MX MXPA00003997A patent/MXPA00003997A/es unknown
- 2000-04-26 GR GR20000100153A patent/GR1003575B/el unknown
- 2000-04-26 CZ CZ20013879A patent/CZ296534B6/cs not_active IP Right Cessation
- 2000-04-26 PT PT102457A patent/PT102457A/pt unknown
- 2000-04-26 SE SE0001518A patent/SE0001518L/xx not_active Application Discontinuation
- 2000-04-26 BR BR0003046-5A patent/BR0003046A/pt not_active IP Right Cessation
- 2000-04-26 GB GB0010199A patent/GB2351663A/en not_active Withdrawn
- 2000-04-26 NL NL1015027A patent/NL1015027C2/nl not_active IP Right Cessation
- 2000-04-26 NZ NZ504163A patent/NZ504163A/en unknown
- 2000-04-26 JP JP2000126472A patent/JP2000336043A/ja active Pending
- 2000-04-26 DE DE20007861U patent/DE20007861U1/de not_active Expired - Lifetime
- 2000-04-26 ID IDP20000331D patent/ID25704A/id unknown
- 2000-04-26 CH CH00819/00A patent/CH692478A5/de not_active IP Right Cessation
- 2000-04-26 ES ES00926367.4T patent/ES2208317T7/es active Active
- 2000-04-26 DZ DZ003171A patent/DZ3171A1/xx active
- 2000-04-26 IE IE20000315A patent/IE20000315A1/en not_active IP Right Cessation
- 2000-04-26 WO PCT/US2000/011129 patent/WO2000066099A2/en not_active Ceased
- 2000-04-26 FI FI20000976A patent/FI20000976A7/fi not_active IP Right Cessation
- 2000-04-26 DK DK00926367T patent/DK1173181T6/en active
- 2000-04-26 NZ NZ514882A patent/NZ514882A/en not_active IP Right Cessation
- 2000-04-26 AU AU30129/00A patent/AU3012900A/en not_active Abandoned
- 2000-04-26 CN CNB008097771A patent/CN1196487C/zh not_active Expired - Lifetime
- 2000-04-26 TR TR2000/01132A patent/TR200001132A3/tr unknown
- 2000-04-26 EP EP00926367.4A patent/EP1173181B3/en not_active Expired - Lifetime
- 2000-04-26 EP EP03023276A patent/EP1415652A3/en not_active Withdrawn
- 2000-04-26 PL PL00339897A patent/PL339897A1/xx not_active Application Discontinuation
- 2000-04-26 MX MXPA01010837A patent/MXPA01010837A/es active IP Right Grant
- 2000-04-26 AT AT00926367T patent/ATE251908T1/de active
- 2000-04-26 FR FR0005296A patent/FR2795646B1/fr not_active Expired - Fee Related
- 2000-04-26 LT LT2000035A patent/LT4758B/lt not_active IP Right Cessation
- 2000-04-26 UA UA2001118182A patent/UA72248C2/uk unknown
- 2000-04-26 DE DE60005940.5T patent/DE60005940T3/de not_active Expired - Lifetime
- 2000-04-26 SK SK1563-2001A patent/SK285415B6/sk not_active IP Right Cessation
- 2000-04-26 KR KR1020017013747A patent/KR100577057B1/ko not_active Ceased
- 2000-04-26 JP JP2000614984A patent/JP4975214B2/ja not_active Expired - Lifetime
- 2000-04-26 DE DE10021266A patent/DE10021266A1/de not_active Withdrawn
- 2000-04-26 IT IT2000MI000922A patent/ITMI20000922A1/it unknown
- 2000-04-26 EA EA200101008A patent/EA005416B1/ru not_active IP Right Cessation
- 2000-04-26 LV LVP-00-56A patent/LV12560B/en unknown
- 2000-04-26 CN CN00106987XA patent/CN1292264A/zh active Pending
- 2000-04-26 CO CO00029997A patent/CO5170493A1/es not_active Application Discontinuation
- 2000-04-26 CA CA002307101A patent/CA2307101C/en not_active Expired - Fee Related
- 2000-04-26 KR KR1020000022108A patent/KR20010020779A/ko not_active Ceased
- 2000-04-26 SI SI200030225T patent/SI1173181T1/xx unknown
- 2000-04-26 HU HU0200912A patent/HU230369B1/hu not_active IP Right Cessation
- 2000-04-26 DK DK200000677A patent/DK200000677A/da not_active Application Discontinuation
- 2000-04-26 AU AU44908/00A patent/AU769946C/en not_active Expired
- 2000-04-26 HR HR20000243A patent/HRP20000243A2/hr not_active Application Discontinuation
- 2000-04-26 ZA ZA200002058A patent/ZA200002058B/xx unknown
- 2000-04-26 PT PT00926367T patent/PT1173181E/pt unknown
- 2000-04-26 IL IL14609800A patent/IL146098A0/xx unknown
- 2000-04-26 HK HK02101474.1A patent/HK1041204B/en not_active IP Right Cessation
- 2000-04-26 HR HR20010778A patent/HRP20010778B1/xx not_active IP Right Cessation
- 2000-04-26 CH CH00926367.4T patent/CH1173181H1/de unknown
- 2000-04-26 LU LU90569A patent/LU90569B1/fr active
- 2000-04-26 SG SG200002287A patent/SG98384A1/en unknown
- 2000-04-26 CA CA002371684A patent/CA2371684C/en not_active Expired - Lifetime
- 2000-04-26 PE PE2000000388A patent/PE20010071A1/es not_active Application Discontinuation
- 2000-04-26 BE BE2000/0295A patent/BE1012957A5/fr not_active IP Right Cessation
- 2000-04-26 BR BR0010181-8A patent/BR0010181A/pt not_active Application Discontinuation
- 2000-04-26 PL PL352629A patent/PL197813B1/pl unknown
- 2000-04-26 EA EA200000355A patent/EA200000355A3/ru unknown
- 2000-04-26 SI SI200000107A patent/SI20361A/sl not_active IP Right Cessation
-
2001
- 2001-10-22 IL IL146098A patent/IL146098A/en not_active IP Right Cessation
- 2001-10-29 NO NO20015275A patent/NO322013B3/no not_active IP Right Cessation
- 2001-10-29 ZA ZA200108900A patent/ZA200108900B/xx unknown
-
2004
- 2004-05-12 AU AU2004201988A patent/AU2004201988A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859006A (en) * | 1994-01-21 | 1999-01-12 | Icos Corporation | Tetracyclic derivatives; process of preparation and use |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150002453A (ko) | 2013-06-28 | 2015-01-07 | 한미약품 주식회사 | 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 저작정 제제 |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100577057B1 (ko) | 단위 제형 | |
| US6943166B1 (en) | Compositions comprising phosphodiesterase inhabitors for the treatment of sexual disfunction | |
| US6451807B1 (en) | Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor | |
| US20030144296A1 (en) | Daily treatment for erectile dysfunction using a PDE5 inhibitor | |
| HK1065485A (en) | Composition comprising phosphodiesterase inhibitors for the treatment of sexual dysfunction |
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Appeal kind category: Invalidation Request date: 20140331 Decision date: 20150925 Appeal identifier: 2014100000799 Patent event date: 20140331 Comment text: Request for Trial Patent event code: PJ02042R01D Patent event date: 20060428 Comment text: Registration of Establishment Patent event code: PJ02041E01I Appeal kind category: Invalidation Request date: 20140331 Decision date: 20150925 Appeal identifier: 2014100000791 |
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