KR100519831B1 - 티에노피롤리디논 - Google Patents

티에노피롤리디논 Download PDF

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Publication number
KR100519831B1
KR100519831B1 KR10-2003-7000084A KR20037000084A KR100519831B1 KR 100519831 B1 KR100519831 B1 KR 100519831B1 KR 20037000084 A KR20037000084 A KR 20037000084A KR 100519831 B1 KR100519831 B1 KR 100519831B1
Authority
KR
South Korea
Prior art keywords
pyrrole
formula
thieno
dihydro
methylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-2003-7000084A
Other languages
English (en)
Korean (ko)
Other versions
KR20030013522A (ko
Inventor
길아드리안리암
해리스윌리엄
Original Assignee
에프. 호프만-라 로슈 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에프. 호프만-라 로슈 아게 filed Critical 에프. 호프만-라 로슈 아게
Publication of KR20030013522A publication Critical patent/KR20030013522A/ko
Application granted granted Critical
Publication of KR100519831B1 publication Critical patent/KR100519831B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR10-2003-7000084A 2000-07-04 2001-06-28 티에노피롤리디논 Expired - Fee Related KR100519831B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0016454.1 2000-07-04
GBGB0016454.1A GB0016454D0 (en) 2000-07-04 2000-07-04 Thienopyrrolidinones
PCT/EP2001/007423 WO2002002567A1 (en) 2000-07-04 2001-06-28 Thienopyrrolidinones

Publications (2)

Publication Number Publication Date
KR20030013522A KR20030013522A (ko) 2003-02-14
KR100519831B1 true KR100519831B1 (ko) 2005-10-06

Family

ID=9895032

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7000084A Expired - Fee Related KR100519831B1 (ko) 2000-07-04 2001-06-28 티에노피롤리디논

Country Status (16)

Country Link
US (1) US6528653B2 (enExample)
EP (1) EP1301517B1 (enExample)
JP (1) JP3878128B2 (enExample)
KR (1) KR100519831B1 (enExample)
CN (1) CN1186346C (enExample)
AR (1) AR030241A1 (enExample)
AT (1) ATE284887T1 (enExample)
AU (2) AU2001287568B2 (enExample)
BR (1) BR0112147A (enExample)
CA (1) CA2414705A1 (enExample)
DE (1) DE60107852T2 (enExample)
ES (1) ES2233677T3 (enExample)
GB (1) GB0016454D0 (enExample)
MX (1) MXPA02012595A (enExample)
PT (1) PT1301517E (enExample)
WO (1) WO2002002567A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004035507A (ja) * 2002-07-05 2004-02-05 Nippon Soda Co Ltd ピロール誘導体及びその製造方法
WO2005012311A1 (en) * 2003-07-31 2005-02-10 Wyeth N-sulfonylheterocyclopyrrolylalkylamine compounds as 5-hydroxytryptamine-6 ligands
CN1939922B (zh) * 2005-09-27 2010-10-13 天津和美生物技术有限公司 可抑制细胞释放肿瘤坏死因子的5H-噻吩[3，4-c]吡咯-4，6-二酮衍生物
US20070185929A1 (en) * 2006-02-01 2007-08-09 Sap Portals Isreal Ltd. Method and apparatus for processing monitoring
TWI873092B (zh) 2018-04-06 2025-02-21 美商百歐克斯製藥公司 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797413A (en) 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4863092A (en) 1988-09-01 1989-09-05 Robertshaw Controls Company Apparatus for making a diaphragm assembly and method of making the apparatus
US5880141A (en) 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
GB9610964D0 (en) 1996-05-24 1996-07-31 Pharmacia & Upjohn Spa Substituted tetralylmethylen-oxindole analogues as tyrosine kinase inhibitors
EP0929520B1 (en) 1996-08-23 2005-11-02 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
AU7622698A (en) 1996-12-05 1998-06-29 Sugen, Inc. Use of indolinone compounds as modulators of protein kinases
CA2289102A1 (en) 1997-05-07 1998-11-12 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
GB9716557D0 (en) 1997-08-06 1997-10-08 Glaxo Group Ltd Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
FR2770215B1 (fr) 1997-10-28 2000-01-14 Pf Medicament Derives d'aminomethyl-benzo[a]quinolizidine, leur preparation et leur application en therapeutique pour les maladies neurodegeneratives
US6153634A (en) 1998-12-17 2000-11-28 Hoffmann-La Roche Inc. 4,5-azolo-oxindoles
ES2301255T3 (es) 1998-12-17 2008-06-16 F. Hoffmann-La Roche Ag 4,5-pirazinaxindoles como inhibidores de proteinoquinasas.

Also Published As

Publication number Publication date
CN1440412A (zh) 2003-09-03
US6528653B2 (en) 2003-03-04
DE60107852T2 (de) 2005-12-08
EP1301517B1 (en) 2004-12-15
ES2233677T3 (es) 2005-06-16
ATE284887T1 (de) 2005-01-15
CA2414705A1 (en) 2002-01-10
BR0112147A (pt) 2003-07-01
GB0016454D0 (en) 2000-08-23
WO2002002567A1 (en) 2002-01-10
JP3878128B2 (ja) 2007-02-07
EP1301517A1 (en) 2003-04-16
AU8756801A (en) 2002-01-14
JP2004502694A (ja) 2004-01-29
CN1186346C (zh) 2005-01-26
MXPA02012595A (es) 2003-04-10
US20020028841A1 (en) 2002-03-07
KR20030013522A (ko) 2003-02-14
AU2001287568B2 (en) 2007-01-11
DE60107852D1 (en) 2005-01-20
AR030241A1 (es) 2003-08-13
PT1301517E (pt) 2005-04-29

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