AR030241A1 - Compuestos derivados de tienopirrolidinona, su uso, medicamentos que los contienen, un procedimiento para preparar dichos compuestos y compuestos intermediarios - Google Patents
Compuestos derivados de tienopirrolidinona, su uso, medicamentos que los contienen, un procedimiento para preparar dichos compuestos y compuestos intermediariosInfo
- Publication number
- AR030241A1 AR030241A1 ARP010103167A ARP010103167A AR030241A1 AR 030241 A1 AR030241 A1 AR 030241A1 AR P010103167 A ARP010103167 A AR P010103167A AR P010103167 A ARP010103167 A AR P010103167A AR 030241 A1 AR030241 A1 AR 030241A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- prepare
- procedure
- contain
- tienopirrolidinona
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
- 201000011529 cardiovascular cancer Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical class O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0016454.1A GB0016454D0 (en) | 2000-07-04 | 2000-07-04 | Thienopyrrolidinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR030241A1 true AR030241A1 (es) | 2003-08-13 |
Family
ID=9895032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010103167A AR030241A1 (es) | 2000-07-04 | 2001-07-03 | Compuestos derivados de tienopirrolidinona, su uso, medicamentos que los contienen, un procedimiento para preparar dichos compuestos y compuestos intermediarios |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6528653B2 (enExample) |
| EP (1) | EP1301517B1 (enExample) |
| JP (1) | JP3878128B2 (enExample) |
| KR (1) | KR100519831B1 (enExample) |
| CN (1) | CN1186346C (enExample) |
| AR (1) | AR030241A1 (enExample) |
| AT (1) | ATE284887T1 (enExample) |
| AU (2) | AU2001287568B2 (enExample) |
| BR (1) | BR0112147A (enExample) |
| CA (1) | CA2414705A1 (enExample) |
| DE (1) | DE60107852T2 (enExample) |
| ES (1) | ES2233677T3 (enExample) |
| GB (1) | GB0016454D0 (enExample) |
| MX (1) | MXPA02012595A (enExample) |
| PT (1) | PT1301517E (enExample) |
| WO (1) | WO2002002567A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004035507A (ja) * | 2002-07-05 | 2004-02-05 | Nippon Soda Co Ltd | ピロール誘導体及びその製造方法 |
| WO2005012311A1 (en) * | 2003-07-31 | 2005-02-10 | Wyeth | N-sulfonylheterocyclopyrrolylalkylamine compounds as 5-hydroxytryptamine-6 ligands |
| CN1939922B (zh) * | 2005-09-27 | 2010-10-13 | 天津和美生物技术有限公司 | 可抑制细胞释放肿瘤坏死因子的5H-噻吩[3，4-c]吡咯-4，6-二酮衍生物 |
| US20070185929A1 (en) * | 2006-02-01 | 2007-08-09 | Sap Portals Isreal Ltd. | Method and apparatus for processing monitoring |
| TWI873092B (zh) | 2018-04-06 | 2025-02-21 | 美商百歐克斯製藥公司 | 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797413A (en) | 1986-05-14 | 1989-01-10 | Merck & Co., Inc. | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use |
| US4863092A (en) | 1988-09-01 | 1989-09-05 | Robertshaw Controls Company | Apparatus for making a diaphragm assembly and method of making the apparatus |
| US5880141A (en) | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| GB9610964D0 (en) | 1996-05-24 | 1996-07-31 | Pharmacia & Upjohn Spa | Substituted tetralylmethylen-oxindole analogues as tyrosine kinase inhibitors |
| EP0929520B1 (en) | 1996-08-23 | 2005-11-02 | Sugen, Inc. | Indolinone combinatorial libraries and related products and methods for the treatment of disease |
| AU7622698A (en) | 1996-12-05 | 1998-06-29 | Sugen, Inc. | Use of indolinone compounds as modulators of protein kinases |
| CA2289102A1 (en) | 1997-05-07 | 1998-11-12 | Sugen, Inc. | 2-indolinone derivatives as modulators of protein kinase activity |
| GB9716557D0 (en) | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
| GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
| FR2770215B1 (fr) | 1997-10-28 | 2000-01-14 | Pf Medicament | Derives d'aminomethyl-benzo[a]quinolizidine, leur preparation et leur application en therapeutique pour les maladies neurodegeneratives |
| US6153634A (en) | 1998-12-17 | 2000-11-28 | Hoffmann-La Roche Inc. | 4,5-azolo-oxindoles |
| ES2301255T3 (es) | 1998-12-17 | 2008-06-16 | F. Hoffmann-La Roche Ag | 4,5-pirazinaxindoles como inhibidores de proteinoquinasas. |
-
2000
- 2000-07-04 GB GBGB0016454.1A patent/GB0016454D0/en not_active Ceased
-
2001
- 2001-06-26 US US09/891,588 patent/US6528653B2/en not_active Expired - Fee Related
- 2001-06-28 AT AT01967106T patent/ATE284887T1/de not_active IP Right Cessation
- 2001-06-28 KR KR10-2003-7000084A patent/KR100519831B1/ko not_active Expired - Fee Related
- 2001-06-28 ES ES01967106T patent/ES2233677T3/es not_active Expired - Lifetime
- 2001-06-28 EP EP01967106A patent/EP1301517B1/en not_active Expired - Lifetime
- 2001-06-28 DE DE60107852T patent/DE60107852T2/de not_active Expired - Fee Related
- 2001-06-28 JP JP2002507819A patent/JP3878128B2/ja not_active Expired - Fee Related
- 2001-06-28 WO PCT/EP2001/007423 patent/WO2002002567A1/en not_active Ceased
- 2001-06-28 AU AU2001287568A patent/AU2001287568B2/en not_active Ceased
- 2001-06-28 MX MXPA02012595A patent/MXPA02012595A/es active IP Right Grant
- 2001-06-28 PT PT01967106T patent/PT1301517E/pt unknown
- 2001-06-28 AU AU8756801A patent/AU8756801A/xx active Pending
- 2001-06-28 CA CA002414705A patent/CA2414705A1/en not_active Abandoned
- 2001-06-28 BR BR0112147-2A patent/BR0112147A/pt not_active IP Right Cessation
- 2001-06-28 CN CNB01812349XA patent/CN1186346C/zh not_active Expired - Fee Related
- 2001-07-03 AR ARP010103167A patent/AR030241A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1440412A (zh) | 2003-09-03 |
| US6528653B2 (en) | 2003-03-04 |
| DE60107852T2 (de) | 2005-12-08 |
| EP1301517B1 (en) | 2004-12-15 |
| ES2233677T3 (es) | 2005-06-16 |
| ATE284887T1 (de) | 2005-01-15 |
| CA2414705A1 (en) | 2002-01-10 |
| BR0112147A (pt) | 2003-07-01 |
| GB0016454D0 (en) | 2000-08-23 |
| WO2002002567A1 (en) | 2002-01-10 |
| JP3878128B2 (ja) | 2007-02-07 |
| EP1301517A1 (en) | 2003-04-16 |
| AU8756801A (en) | 2002-01-14 |
| JP2004502694A (ja) | 2004-01-29 |
| CN1186346C (zh) | 2005-01-26 |
| MXPA02012595A (es) | 2003-04-10 |
| US20020028841A1 (en) | 2002-03-07 |
| KR100519831B1 (ko) | 2005-10-06 |
| KR20030013522A (ko) | 2003-02-14 |
| AU2001287568B2 (en) | 2007-01-11 |
| DE60107852D1 (en) | 2005-01-20 |
| PT1301517E (pt) | 2005-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |