AU2001287568B2 - Thienopyrrolidinones - Google Patents

Thienopyrrolidinones Download PDF

Info

Publication number
AU2001287568B2
AU2001287568B2 AU2001287568A AU2001287568A AU2001287568B2 AU 2001287568 B2 AU2001287568 B2 AU 2001287568B2 AU 2001287568 A AU2001287568 A AU 2001287568A AU 2001287568 A AU2001287568 A AU 2001287568A AU 2001287568 B2 AU2001287568 B2 AU 2001287568B2
Authority
AU
Australia
Prior art keywords
optionally substituted
dihydro
thieno
pyrrol
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001287568A
Other languages
English (en)
Other versions
AU2001287568A1 (en
Inventor
Adrian Liam Gill
William Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2001287568A1 publication Critical patent/AU2001287568A1/en
Application granted granted Critical
Publication of AU2001287568B2 publication Critical patent/AU2001287568B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2001287568A 2000-07-04 2001-06-28 Thienopyrrolidinones Ceased AU2001287568B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0016454.1 2000-07-04
GBGB0016454.1A GB0016454D0 (en) 2000-07-04 2000-07-04 Thienopyrrolidinones
PCT/EP2001/007423 WO2002002567A1 (en) 2000-07-04 2001-06-28 Thienopyrrolidinones

Publications (2)

Publication Number Publication Date
AU2001287568A1 AU2001287568A1 (en) 2002-04-11
AU2001287568B2 true AU2001287568B2 (en) 2007-01-11

Family

ID=9895032

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001287568A Ceased AU2001287568B2 (en) 2000-07-04 2001-06-28 Thienopyrrolidinones
AU8756801A Pending AU8756801A (en) 2000-07-04 2001-06-28 Thienopyrrolidinones

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU8756801A Pending AU8756801A (en) 2000-07-04 2001-06-28 Thienopyrrolidinones

Country Status (16)

Country Link
US (1) US6528653B2 (enExample)
EP (1) EP1301517B1 (enExample)
JP (1) JP3878128B2 (enExample)
KR (1) KR100519831B1 (enExample)
CN (1) CN1186346C (enExample)
AR (1) AR030241A1 (enExample)
AT (1) ATE284887T1 (enExample)
AU (2) AU2001287568B2 (enExample)
BR (1) BR0112147A (enExample)
CA (1) CA2414705A1 (enExample)
DE (1) DE60107852T2 (enExample)
ES (1) ES2233677T3 (enExample)
GB (1) GB0016454D0 (enExample)
MX (1) MXPA02012595A (enExample)
PT (1) PT1301517E (enExample)
WO (1) WO2002002567A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004035507A (ja) * 2002-07-05 2004-02-05 Nippon Soda Co Ltd ピロール誘導体及びその製造方法
WO2005012311A1 (en) * 2003-07-31 2005-02-10 Wyeth N-sulfonylheterocyclopyrrolylalkylamine compounds as 5-hydroxytryptamine-6 ligands
CN1939922B (zh) * 2005-09-27 2010-10-13 天津和美生物技术有限公司 可抑制细胞释放肿瘤坏死因子的5H-噻吩[3，4-c]吡咯-4，6-二酮衍生物
US20070185929A1 (en) * 2006-02-01 2007-08-09 Sap Portals Isreal Ltd. Method and apparatus for processing monitoring
TWI873092B (zh) 2018-04-06 2025-02-21 美商百歐克斯製藥公司 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797413A (en) 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4863092A (en) 1988-09-01 1989-09-05 Robertshaw Controls Company Apparatus for making a diaphragm assembly and method of making the apparatus
US5880141A (en) 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
GB9610964D0 (en) 1996-05-24 1996-07-31 Pharmacia & Upjohn Spa Substituted tetralylmethylen-oxindole analogues as tyrosine kinase inhibitors
EP0929520B1 (en) 1996-08-23 2005-11-02 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
AU7622698A (en) 1996-12-05 1998-06-29 Sugen, Inc. Use of indolinone compounds as modulators of protein kinases
CA2289102A1 (en) 1997-05-07 1998-11-12 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
GB9716557D0 (en) 1997-08-06 1997-10-08 Glaxo Group Ltd Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
FR2770215B1 (fr) 1997-10-28 2000-01-14 Pf Medicament Derives d'aminomethyl-benzo[a]quinolizidine, leur preparation et leur application en therapeutique pour les maladies neurodegeneratives
US6153634A (en) 1998-12-17 2000-11-28 Hoffmann-La Roche Inc. 4,5-azolo-oxindoles
ES2301255T3 (es) 1998-12-17 2008-06-16 F. Hoffmann-La Roche Ag 4,5-pirazinaxindoles como inhibidores de proteinoquinasas.

Also Published As

Publication number Publication date
CN1440412A (zh) 2003-09-03
US6528653B2 (en) 2003-03-04
DE60107852T2 (de) 2005-12-08
EP1301517B1 (en) 2004-12-15
ES2233677T3 (es) 2005-06-16
ATE284887T1 (de) 2005-01-15
CA2414705A1 (en) 2002-01-10
BR0112147A (pt) 2003-07-01
GB0016454D0 (en) 2000-08-23
WO2002002567A1 (en) 2002-01-10
JP3878128B2 (ja) 2007-02-07
EP1301517A1 (en) 2003-04-16
AU8756801A (en) 2002-01-14
JP2004502694A (ja) 2004-01-29
CN1186346C (zh) 2005-01-26
MXPA02012595A (es) 2003-04-10
US20020028841A1 (en) 2002-03-07
KR100519831B1 (ko) 2005-10-06
KR20030013522A (ko) 2003-02-14
DE60107852D1 (en) 2005-01-20
AR030241A1 (es) 2003-08-13
PT1301517E (pt) 2005-04-29

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired