KR100453979B1 - 인데노인돌론 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물 - Google Patents

인데노인돌론 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물 Download PDF

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KR100453979B1
KR100453979B1 KR10-2002-0014738A KR20020014738A KR100453979B1 KR 100453979 B1 KR100453979 B1 KR 100453979B1 KR 20020014738 A KR20020014738 A KR 20020014738A KR 100453979 B1 KR100453979 B1 KR 100453979B1
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KR20020074420A (ko
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미셀 위에르즈비키
마리-프랑소와즈 부사르
앤 루소
쟝-알베르 부땡
필립 드라그랑제
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르 라보레또레 쎄르비에르
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR10-2002-0014738A 2001-03-19 2002-03-19 인데노인돌론 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물 Expired - Fee Related KR100453979B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR01.03667 2001-03-19
FR0103667A FR2822153B1 (fr) 2001-03-19 2001-03-19 Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
KR20020074420A KR20020074420A (ko) 2002-09-30
KR100453979B1 true KR100453979B1 (ko) 2004-10-20

Family

ID=8861264

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Application Number Title Priority Date Filing Date
KR10-2002-0014738A Expired - Fee Related KR100453979B1 (ko) 2001-03-19 2002-03-19 인데노인돌론 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물

Country Status (24)

Country Link
US (1) US6844445B2 (enExample)
EP (1) EP1245565B1 (enExample)
JP (1) JP3886829B2 (enExample)
KR (1) KR100453979B1 (enExample)
CN (1) CN1185214C (enExample)
AR (1) AR034861A1 (enExample)
AT (1) ATE250578T1 (enExample)
AU (1) AU780027B2 (enExample)
BR (1) BR0200871A (enExample)
CA (1) CA2378628C (enExample)
DE (1) DE60200041T2 (enExample)
DK (1) DK1245565T3 (enExample)
EA (1) EA004711B1 (enExample)
ES (1) ES2207629T3 (enExample)
FR (1) FR2822153B1 (enExample)
HK (1) HK1049159B (enExample)
HU (1) HU226674B1 (enExample)
MX (1) MXPA02002816A (enExample)
NO (1) NO321890B1 (enExample)
NZ (1) NZ517855A (enExample)
PL (1) PL352866A1 (enExample)
PT (1) PT1245565E (enExample)
SI (1) SI1245565T1 (enExample)
ZA (1) ZA200202220B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
ES2580702B1 (es) 2015-02-25 2017-06-08 Palobiofarma, S.L. Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina
BR112020005489A2 (pt) 2017-09-22 2020-09-24 Jubilant Epipad Llc, composto da fórmula (i), composto de fórmula (ii), composto de fórmula (iii), processo de preparação de compostos de fórmula (i), processo de preparação de compostos de fórmula (ii), processo de preparação de compostos de fórmula (iii), composição farmacêutica, método para inibir uma ou mais famílias pad em uma célula, método para tratar uma afeção mediada por um ou mais pads, utilização do composto, método para o tratamento e/ou prevenção de uma afeção mediada por um ou mais distúrbios da família pad, método para o tratamento de artrite reumatoide e método de tratamento de câncer
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
EP3707135A1 (en) 2017-11-06 2020-09-16 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as prmt5 inhibitors
EP3765453A1 (en) 2018-03-13 2021-01-20 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0481708A1 (en) * 1990-10-16 1992-04-22 University Of Bath Indenoindole compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0481708A1 (en) * 1990-10-16 1992-04-22 University Of Bath Indenoindole compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
bill, Kevin; Black, Gerald G.; Falshaw, Christopher P; Heterocycles; 20(12); pp2433~2436 *
Martarello,L; Kirsch, G; Wierzbicki, M.; Heterocyclic Communications; 3(1) pp51~56;1996 *

Also Published As

Publication number Publication date
EP1245565A1 (fr) 2002-10-02
EA200200263A3 (ru) 2002-12-26
ES2207629T3 (es) 2004-06-01
EP1245565B1 (fr) 2003-09-24
ATE250578T1 (de) 2003-10-15
AR034861A1 (es) 2004-03-24
CN1375490A (zh) 2002-10-23
FR2822153B1 (fr) 2003-10-31
HK1049159B (zh) 2005-07-29
BR0200871A (pt) 2003-01-07
DE60200041D1 (de) 2003-10-30
SI1245565T1 (en) 2003-12-31
EA004711B1 (ru) 2004-06-24
HUP0201024A3 (en) 2003-12-29
CA2378628A1 (fr) 2002-09-19
CA2378628C (fr) 2007-07-10
HU0201024D0 (enExample) 2002-05-29
NO20021330D0 (no) 2002-03-18
KR20020074420A (ko) 2002-09-30
AU780027B2 (en) 2005-02-24
PT1245565E (pt) 2003-12-31
NO20021330L (no) 2002-09-20
EA200200263A2 (ru) 2002-10-31
JP2002322150A (ja) 2002-11-08
DE60200041T2 (de) 2004-06-09
HK1049159A1 (en) 2003-05-02
CN1185214C (zh) 2005-01-19
US20020173531A1 (en) 2002-11-21
ZA200202220B (en) 2002-10-10
NZ517855A (en) 2002-10-25
US6844445B2 (en) 2005-01-18
FR2822153A1 (fr) 2002-09-20
AU2746902A (en) 2002-09-26
PL352866A1 (en) 2002-09-23
HU226674B1 (en) 2009-06-29
NO321890B1 (no) 2006-07-17
DK1245565T3 (da) 2004-01-12
MXPA02002816A (es) 2004-11-12
JP3886829B2 (ja) 2007-02-28
HUP0201024A2 (hu) 2002-11-28

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