KR100450389B1 - Oral liquid composition for removing bad breath - Google Patents

Abstract

The present invention relates to a liquid composition for oral cavity comprising 0.5 to 10.0% by weight of bamboo salt and 0.01 to 10.0% by weight of (+)-catechin-containing green tea extract.

Description

Oral liquid composition for removing bad breath

The present invention relates to an oral liquid composition for removing bad breath containing bamboo salt and green tea extract. More specifically, the present invention relates to a liquid composition for oral cavity having an excellent bad breath removing effect by using green tea extract containing bamboo salt and flavonoid of (+) catechin.

In general, bad breath is caused by acquired systemic diseases, proteins in the saliva, food residues, etc., are broken down by microorganisms in the oral cavity, and amino acids are decomposed by dehumidifying enzymes or amino enzymes to produce odor-inducing substances. Is generated. In addition, when ingesting garlic or red pepper, bad breath is also caused by sulfides contained in these substances.

Bad breath causes volatile sulfide (Volatile Sulfide Compounds: VSC), hydrogen sulfide (H ₂ S), methyl mercaptan (CH ₃ SH), dimethyl mercapptan (CH ₃ ) ₂ S), and other bad breath-causing substances include aldehydes, fatty acids, ammonia, amines or pyridine. Although Sage or Rothmari was used in Japanese Unexamined Patent Publication No. 60-75418 as a bad breath removal effect component, all these components are known to be difficult to obtain a continuous bad breath removal effect.

As a result of numerous studies to improve these disadvantages of the prior art, the inventors have found that the addition of Green Sinensis L. extract containing bamboo salt and flavonoids of (+)-catechin to the conventional liquid composition for oral cavity It has been found to have a lasting and strong deodorant effect.

Bamboo salt is bamboo and salt which is synthesized by fire method. It is a bamboo which produces new cells and the salt which prevents sterilization and rot. It has been known as elixir that removes toxins and improves its maximal efficacy by repeatedly treating with heat several times in iii).

The salt used in the manufacture of bamboo salt is usually used as a salt, and in addition to food salts, rock salt, reagent grade sodium chloride and potassium chloride, bamboo or cotton bamboo are used as bamboo, but There is no need to limit it.

Bamboo salt used in the present invention is commercially available as bamboo and ocher, which acts on cell generation, and salt that prevents sterilization and rot, are repeatedly treated with high heat (over 1000 ° C) in a furnace to remove toxins, and The effects are increased as much as possible.

Bamboo and salt, the ingredients used for bamboo salts, can be found in bamboo, which contains ingredients such as cyanine, peonine, cyanidin, peonidine, galactose, toothache, gum bleeding, cold symptoms, tumors, and cell viability. It is described in Dongbobogam, Herbal Botany, New Nongshim, and Native Korean Medicinal Plants. Its salt has a high osmotic effect to disinfect and disinfect and bleeds gums, swelling, inflammation and bad breath. There is a consent statement, herbaceous persimmons, new agricultural plants, etc. are listed.

The used bamboo salt of the present invention can be prepared by the following method. Cut the bamboo which grew under sea breeze (3 years old is suitable), and cut it one by one to block one side, and squeeze the sun-dried salt into the container and beat the manure-free soil in the mountain nine times, and dry it in the shade. After kneading, put about 1cm of red pine leaf, reinforcement mugwort, and leaves, and seal it with the clay soil kneaded about 2cm at the end. Several bamboos are made and the pine is placed on a porcelain kiln made of ocher, sprinkled with rosin, and set on fire (room temperature 1000 ℃). Take it out after about 24 hours (at this time, only bamboo, red pine, mugwort, and salty soil that absorbed the loess of the loess), then crush the salt mass finely and add salt to the new bamboo barrel in the same way as the first. Repeat eight times, and add salt to a new bamboo barrel on the ninth and repeat the method eight times. On the ninth, make a special high in the basement to make a high temperature (1500 ℃). If you melt the fire with only the paper and melt it down, it will flow like the waste water of the furnace, and when the fire goes out, this liquid will harden and turn like a stone. This mass is bamboo salt and crushed properly.

The efficacy and effect of bamboo salt include detoxification, anti-blood effect, anti-inflammatory action, cell regeneration, constitution improvement, antibacterial action, anti-cancer effect, etc. It is effective for cold symptoms, etc. Kim In-hoon's new medicine (神 藥. 1986), Lee Kwon-ik, etc. New Medicine (神 方藥. 1989).

Flavonoids are natural complexes mainly contained in camellia plants such as green tea, and polyphenol derivatives are commonly referred to as flavonoids. The Japanese Society for Textile Machinery (Vol. 40 No. 3, 1987) describes that polyphenol derivatives having a three-dimensional structure and the like contain a molecule or an atom of an odor component to remove odors. Green tea extract contains mainly caffeine and other organic acids, amino acids, (+)-catechins, sugars, etc. Among them, the (+)-catechins having a three-dimensional structure of polyphenol derivatives are sustained by the inclusion action. Reduce bad breath. Flavonoids are represented by the following chemical structure (I), the chemical structures of the representative flavonoids are shown in Table 1 below.

TABLE 1 Representative Flavonoid Structures

In general, flavonoids have excellent anti-inflammatory and antibacterial effects against swelling at the inflammatory site, excellent cell protection, and excellent anti-aging effects on the skin, and also acts on animal cancer cells to inhibit cancer development and It is known to have antimutagenic effects.

In addition, it acts to lower blood pressure by inhibiting angiotensin transfer enzyme that causes high blood pressure and relaxes platelets. In addition, it also has an effect of inhibiting arteriosclerosis by reducing the concentration of cholesterol in blood.

The present invention relates to a liquid composition for removing oral bad breath, which comprises 0.5 to 10% by weight of bamboo salt and 0.01 to 10% by weight of (+)-catechin-containing green tea extract in the conventional liquid composition for oral cavity.

The liquid composition for oral cavity according to the present invention preferably uses 1.0 to 5.0% by weight of bamboo salt and 0.1 to 5.0% by weight of green tea extract, and the mixing ratio of bamboo salt and green tea extract is used as 1: 1 to 10: 1.

In the liquid composition for oral cavity according to the present invention, if the salt is less than 0.5% by weight, green tea extract 0.01% by weight or less, and the mixing ratio is outside the range of (1: 1) to (10: 1), sufficient bad breathing effect cannot be expected In addition, when used in more than 10% by weight of bamboo salt, more than 10% by weight of green tea extract makes it feel uncomfortable when used as the smell of bamboo salt and the smell of green tea extract, there is a problem that the components are precipitated in the nature of the formulation.

Hereinafter, the liquid composition for oral cavity of the present invention will be described in detail.

In general, the liquid composition for oral cavity can be divided into alcohol and purified water, it is prepared by dissolving the various components in the easy to dissolve the mixed head phase.

Surfactants have been used as solubilizers to solubilize fragrances in water, and the most commonly used surfactants are polyoxyethylene polyoxypropylene copolymerized polymers, polyoxyethylene hardened castor oil, higher alkyl acetates and polyoxy of sorbitan fatty acid esters. Ethylene derivatives and the like, and preferred are polyoxyethylene polyoxypropylene copolymerized polymers of polyoxyethylene cured castor oil. The amount of solubilizer used is generally 0.1 to 3.0% by weight, preferably 0.5 to 3.0% by weight.

In the present invention, wetting agents are used to give stability, sweetness and slight viscosity of the product. Wetting agents include glycerin, sorbitol liquid, amorphous sorbitol liquid, propylene glycol, and the like, and preferred are glycerin and amorphous sorbitol liquid. The amount of such humectant is generally 3.0 to 40% by weight, preferably 5 to 25% by weight.

Ethanol is used to soften the product and dissolve flavors and preservatives that are insoluble in water.In general, the higher the ethanol content, the better the perfume's dissipation power. do. In general, the amount of ethanol is 5.0 to 30% by weight, preferably 5.0 to 20% by weight.

Flavors and sweeteners are used to improve the user's feel. Flavors are fragrant substances used in conventional toothpaste and food fragrances. They are used in peppermint oil, menthol, spearmint oil and carr Bones, Anise oil, Anitol, Eucalyptus oil, Eucalyptol (1,8-cineol), Clove oil, Eugenol, Wintergreen oil, Methyl silicate, Cinnamon oil, Cinnamicaldehyde and other flavoring ingredients It is used, the material constituting the fragrance (Fl-avor) is a total amount of one kind or a mixture of two or more is 0.01 to 2.0% by weight, preferably 0.1 to 1.0% by weight.

Examples of sweeteners include lactose, sorbitol, ispartame, and saccharin sodium, and in general, it is appropriate to use 0.001 to 0.1 wt% of saccharin sodium.

The liquid composition for oral cavity according to the present invention may further contain a preservative, a buffer, a pigment, and the like. Double preservative is mainly used 0.001 to 0.1% by weight of sodium benzoate salt or a mixture of two or more thereof.

Buffers are used to adjust the pH of the liquid composition for oral cavities, the buffers being mainly sodium primary phosphate, secondary sodium phosphate and tertiary sodium phosphate, citric acid and sodium citrate, tartaric acid and sodium stannate, boric acid, phosphoric acid, hydrochloric acid, Sodium hydroxide and the like are mainly used, but preferably one or two or more kinds of first sodium phosphate and third sodium phosphate are used. In addition, in order to increase the commercial value of the liquid composition for oral cavity and to meet the purpose of use, pigments are used mainly food coloring.

Hereinafter, the present invention will be described in detail with examples and comparative examples, but the technical scope of the present invention is not limited in any way by these.

Example: Oral liquid composition for removing bad breath

Experimental Example: Clinical comparison experiment on the effect of inhibiting bad breath of the present invention toothpaste (Examples 1 to 10) and comparative toothpaste (Comparative Examples 1 to 7)

1) Subject

85 males and females in their 20s with no dental caries were selected and 5 subjects per toothpaste were tested.

2) Experiment Method

After chewing a certain amount of garlic (0.5g) for 2 minutes to generate an oral bad breath, and then brushed with toothpaste for 1 minute and after 1 minute, 5 minutes, 10 minutes, 15 minutes, the amount of methylmercaptan that is bad breath is measured. Keep your mouth closed except when brushing to prevent mixing of the subject's breath with outside air. The exhalation is measured by gas chromatography (FPD) after taking 100 ml using a gas suction injection machine (Gas Tighter Syringe). At this time, a 1 ml sample loop is attached to analyze only 1 ml of exhalation. The column uses a Chromosil 330, a filling length of 6 feet and an outer diameter of 1/8 inch Teflon tube. The column temperature is adjusted to 70 ° C and helium is used as a carrier gas at 20 ml / min.

3) Experimental Result: Methylmercaptan Reduction (%)

According to the results of experiments of measuring the toothpaste and the comparative toothpaste three times by the above method by gas chromatography, the time-dependent decrease of methylmercaptan produced during garlic mastication was determined using bamboo extract and green tea extract containing (+)-catechin. The toothpaste used was 88.5% to 98.9%, much better than 67.7% to 88.7% of the comparative toothpaste, especially toothpaste using at least 1.0% by weight of bamboo salt and 0.1% by weight or more of green tea extract. Therefore, toothpaste using a mixture of bamboo salt and green tea extract is considered to have an excellent bad breath removal effect than toothpaste using only one toothpaste and other ingredients.

Claims (4)

Oral liquid composition for removing bad breath, comprising bamboo salt and (+)-catechin-containing green tea extract. The oral liquid composition according to claim 1, which contains 0.5 to 10.0 wt% of bamboo salt. The oral liquid composition according to claim 1, which contains 0.01 to 10.0% by weight of green tea extract. The liquid composition for oral cavity according to claim 1, wherein the ratio of bamboo salt and green tea extract is (1: 1) to (10: 1).