KR102610236B1 - Toothpaste composition for improving or preventing bad breath - Google Patents
Toothpaste composition for improving or preventing bad breath Download PDFInfo
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- KR102610236B1 KR102610236B1 KR1020230122025A KR20230122025A KR102610236B1 KR 102610236 B1 KR102610236 B1 KR 102610236B1 KR 1020230122025 A KR1020230122025 A KR 1020230122025A KR 20230122025 A KR20230122025 A KR 20230122025A KR 102610236 B1 KR102610236 B1 KR 102610236B1
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- South Korea
- Prior art keywords
- extract
- weight
- natural
- mixture
- sodium
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
Abstract
본 발명은 구취 개선 효과가 있는 치약 조성물에 관한 것이다. 본 발명은 천연 추출물 혼합물, 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 자몽 종자 추출물, 녹차 추출물, 프로폴리스 추출물, 캐모마일 추출물, 로즈마리 추출물, 금은화 추출물, 병풀 추출물, 황금 추출물, 카렌듀라 추출물, 피마자 오일, 고삼 추출물, 매스틱 오일, L-멘톨 및 페퍼민트 오일을 포함하는 것인, 구취 예방 또는 개선용 치약 조성물을 제공한다.The present invention relates to a toothpaste composition that has a bad breath improvement effect. The present invention includes a mixture of natural extracts, silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water, The natural extract mixture includes grapefruit seed extract, green tea extract, propolis extract, chamomile extract, rosemary extract, honeysuckle extract, centella asiatica extract, goldenrod extract, calendura extract, castor oil, sophora extract, mastic oil, L-menthol and peppermint. Provided is a toothpaste composition for preventing or improving bad breath, which includes oil.
Description
본 발명은 구취 예방 또는 개선용 치약 조성물에 관한 것이다.The present invention relates to a toothpaste composition for preventing or improving bad breath.
치약은 치아를 청결하게 하고, 치아의 표면에 달라붙은 불순물을 제거할 목적으로 칫솔에 묻혀 사용하는 분말이나 크림 또는 액상의 약물성 복합물질을 일컫는데, 소독작용, 치석용해작용, 냄새감퇴작용 및 충치나 치조농루 등의 예방 또는 치료에 도움을 준다.Toothpaste refers to a powder, cream, or liquid drug compound used on a toothbrush for the purpose of cleaning teeth and removing impurities stuck to the surface of teeth. It has disinfecting, tartar-dissolving, odor-reducing and It helps prevent or treat cavities or pyorrhea.
이와 같은 치약은 치아에 부착된 치구, 치석 따위를 제거하며 치아면에 본래의 광택을 부여하는 역할을 하는 연마제와, 배합된 계면활성제의 작용으로 사용시의 계면장력을 저하시켜 칫솔질의 청소효과를 높이고 배합되어 있는 약효제의 분산, 침투성을 도와주는 역할을 하는 발포제와, 치약에 습기와 크림상을 주기 위하여 치약이 공기 중에 접촉하여 고체화되는 것을 방지하는 역할을 하는 습윤제와, 치약의 고체성분과 액체성분의 분리를 방지하는 역할을 하는 점결제와, 충치예방, 농루예방, 치아미백, 치석의 침착방지, 구취예방 등의 효과를 증강하기위 한 약효성분, 착색제 및 보존제 등이 함유된다.This kind of toothpaste improves the cleaning effect of toothbrushing by lowering the interfacial tension during use through the action of an abrasive that removes plaque and tartar attached to the teeth and gives the original gloss to the tooth surface, and a blended surfactant. A foaming agent that helps the dispersion and penetration of the mixed medicinal agent, a humectant that prevents the toothpaste from solidifying on contact with the air to give the toothpaste moisture and a creamy appearance, and the solid ingredients and liquid of the toothpaste. It contains a binder that acts to prevent separation of ingredients, and medicinal ingredients, colorants, and preservatives to enhance the effects of preventing cavities, preventing pyorrhea, whitening teeth, preventing deposition of tartar, and preventing bad breath.
한편, 구강에 발생하는 각종 질환은 구강 내에 생성되는 플라그 및 수많은 세균에 의해 유발되는데, 플라그는 스트렙토코커스 뮤탄스(Streptococcus mutans) 등과 같이 구강 내에 서식하는 세균에 의하여 만들어지는 점착성 물질이며, 이는 치아의 표면과 잇몸에 부착된 끈적끈적한 막으로, 구강 세균이 포도당 중합체인 덱스트란의 그물망 속에 갇혀 있는 치면 세균막으로 구성되며 치아 및 그 주변조직에 발생되는 중요한 질병인 충치, 치석 및 잇몸질환의 주요발병 원인으로 알려져 있다. Meanwhile, various diseases that occur in the oral cavity are caused by plaque and numerous bacteria generated in the oral cavity. Plaque is a sticky substance produced by bacteria living in the oral cavity, such as Streptococcus mutans, and it is a sticky substance that acts on the teeth. It is a sticky film attached to the surface and gums, and consists of dental biofilm, in which oral bacteria are trapped in a network of dextran, a glucose polymer. It is the main cause of cavities, tartar, and gum disease, which are important diseases that occur in teeth and surrounding tissues. It is known as
또한, 상기 플라그는 구강 내 타액중 칼슘, 마그네슘 및 인 등의 성분과 결합하여 난용성 염을 형성하여 치아와 유사한 경도를 가진 치석으로 변환되는데, 이렇게 발생되는 치석은 잇몸과 치아의 경계면을 파고들어 양치시 쉽게 출혈을 유발시키고 또한 구강 내 세균에 의해 구취를 유발시킨다.In addition, the plaque combines with components such as calcium, magnesium, and phosphorus in oral saliva to form poorly soluble salts, which are converted into tartar with a hardness similar to that of teeth. The tartar thus generated penetrates into the interface between the gums and teeth. It easily causes bleeding when brushing teeth and also causes bad breath due to bacteria in the oral cavity.
본 발명은 구취 개선 효과가 있으며, 친환경 추출물을 포함하는 치약 조성물을 제공하는 것을 목적으로 한다.The purpose of the present invention is to provide a toothpaste composition that has a bad breath improvement effect and includes an eco-friendly extract.
본 개시의 목적들은 이상에서 언급한 목적으로 제한되지 않으며, 언급되지 않은 본 개시의 다른 목적 및 장점들은 하기의 설명에 의해서 이해될 수 있고, 본 개시의 실시 예에 의해 보다 분명하게 이해될 것이다. 또한, 본 개시의 목적 및 장점들은 특허 청구 범위에 나타낸 수단 및 그 조합에 의해 실현될 수 있음을 쉽게 알 수 있을 것이다.The objects of the present disclosure are not limited to the purposes mentioned above, and other objects and advantages of the present disclosure that are not mentioned can be understood by the following description and will be more clearly understood by the examples of the present disclosure. Additionally, it will be readily apparent that the objects and advantages of the present disclosure can be realized by the means and combinations thereof indicated in the patent claims.
본 발명은 천연 추출물 혼합물, 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 자몽 종자 추출물, 녹차 추출물, 프로폴리스 추출물, 캐모마일 추출물, 로즈마리 추출물, 금은화 추출물, 병풀 추출물, 황금 추출물, 카렌듀라 추출물, 피마자 오일, 고삼 추출물, 매스틱 오일, L-멘톨 및 페퍼민트 오일을 포함하는 것인, 구취 예방 또는 개선용 치약 조성물을 제공한다.The present invention includes a mixture of natural extracts, silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water, The natural extract mixture includes grapefruit seed extract, green tea extract, propolis extract, chamomile extract, rosemary extract, honeysuckle extract, centella asiatica extract, goldenrod extract, calendura extract, castor oil, sophora extract, mastic oil, L-menthol and peppermint. Provided is a toothpaste composition for preventing or improving bad breath, which includes oil.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다.The natural extract mixture contains 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, and 1% by weight of rosemary extract, based on 100% by weight of the natural extract mixture. ~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight, goldenrod extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~ It may contain 3% by weight, 0.1 to 2% by weight of mastic oil, 10 to 20% by weight of L-menthol, and the remainder of peppermint oil.
상기 천연 추출물 혼합물은 황칠나무 추출물 및 복숭아꽃 추출물을 추가로 포함하는 것일 수 있다.The natural extract mixture may further include Hwangchil tree extract and peach blossom extract.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, 황칠나무 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다.The natural extract mixture contains 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, and 1% by weight of rosemary extract, based on 100% by weight of the natural extract mixture. ~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight, goldenrod extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~ It may contain 3% by weight, 0.1 to 2% by weight of mastic oil, 3 to 5% by weight of Hwangchil tree extract, 3 to 5% by weight of peach blossom extract, 10 to 20% by weight of L-menthol, and the remainder of peppermint oil.
또한, 본 발명은 자몽 종자 추출물, 녹차 추출물, 프로폴리스 추출물, 캐모마일 추출물, 로즈마리 추출물, 금은화 추출물, 병풀 추출물, 황금 추출물, 카렌듀라 추출물, 피마자 오일, 고삼 추출물, 매스틱 오일, L-멘톨 및 페퍼민트 오일을 혼합하여 천연 추출물 혼합물을 제조하는 단계; 상기 천연 추출물 혼합물과 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 혼합하는 단계;를 포함하는, 구취 예방 또는 개선용 치약 조성물의 제조 방법을 제공한다.In addition, the present invention includes grapefruit seed extract, green tea extract, propolis extract, chamomile extract, rosemary extract, honeysuckle extract, centella asiatica extract, goldenrod extract, calendura extract, castor oil, sophora extract, mastic oil, L-menthol and peppermint. mixing oils to prepare a natural extract mixture; Mixing the natural extract mixture with silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water; A method for producing a toothpaste composition for preventing or improving bad breath is provided.
상기 제조 방법은, 복숭아꽃을 에탄올로 가열하여 추출하고, 여과하여 복숭아꽃 추출물을 제조하는 단계; 황칠나무를 에탄올로 가열하여 추출하고, 여과하여 황칠나무 추출물을 제조하는 단계;를 추가로 포함하며, 상기 천연추출물 혼합물을 제조하는 단계는, 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, 황칠나무 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 혼합하여 제조하는 단계인 구취 예방 또는 개선용 치약 조성물의 제조 방법을 제공할 수 있다.The manufacturing method includes the steps of extracting peach blossoms by heating them with ethanol and filtering them to produce peach blossom extract; It further includes the step of extracting Hwangchil tree by heating it with ethanol and filtering it to prepare Hwangchil tree extract, wherein the step of preparing the natural extract mixture includes grapefruit seed extract 1 to 3 based on 100% by weight of the natural extract mixture. Weight%, green tea extract 20~30% by weight, propolis extract 0.1~1% by weight, chamomile extract 1~3% by weight, rosemary extract 1~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight %, golden extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~3% by weight, mastic oil 0.1~2% by weight, Hwangchil extract 3~5 A method for producing a toothpaste composition for preventing or improving bad breath can be provided, which is a step of mixing 3 to 5% by weight of peach blossom extract, 10 to 20% by weight of L-menthol, and the remaining peppermint oil.
본 발명은 구취 개선 효과가 있으며, 친환경 천연 추출물을 포함하는 치약 조성물을 제공할 수 있다.The present invention can provide a toothpaste composition that has a bad breath improvement effect and includes an eco-friendly natural extract.
본 발명은 천연 추출물 혼합물, 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 자몽 종자 추출물, 녹차 추출물, 프로폴리스 추출물, 캐모마일 추출물, 로즈마리 추출물, 금은화 추출물, 병풀 추출물, 황금 추출물, 카렌듀라 추출물, 피마자 오일, 고삼 추출물, 매스틱 오일, L-멘톨 및 페퍼민트 오일을 포함하는 것인, 구취 예방 또는 개선용 치약 조성물을 제공한다.The present invention includes a mixture of natural extracts, silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water, The natural extract mixture includes grapefruit seed extract, green tea extract, propolis extract, chamomile extract, rosemary extract, honeysuckle extract, centella asiatica extract, goldenrod extract, calendura extract, castor oil, sophora extract, mastic oil, L-menthol and peppermint. Provided is a toothpaste composition for preventing or improving bad breath, which includes oil.
본 명세서에서, "예방"이란, 본 발명에 따른 치약 조성물의 사용에 의해 구취의 발생을 억제시키거나 지연시키는 모든 행위를 의미한다. In this specification, “prevention” means all actions that suppress or delay the occurrence of bad breath by using the toothpaste composition according to the present invention.
본 명세서에서, "개선"이란, 본 발명에 따른 치약 조성물의 사용에 의해 구취의 증상을 완화, 감소, 또는 소멸시키는 등 그 증세를 호전시키거나 이롭게 변경하는 모든 행위를 의미한다.In this specification, “improvement” means any action that improves or beneficially changes the symptoms of bad breath, such as alleviating, reducing, or eliminating the symptoms of bad breath by using the toothpaste composition according to the present invention.
상기 자몽 종자 추출물, 녹차 추출물, 프로폴리스 추출물, 캐모마일 추출물, 로즈마리 추출물, 금은화 추출물, 병풀 추출물, 황금 추출물, 카렌듀라 추출물, 피마자 오일, 고삼 추출물, 매스틱 오일은 각 원료 성분들을 열수 추출한 열수 추출물을 사용할 수 있다.The grapefruit seed extract, green tea extract, propolis extract, chamomile extract, rosemary extract, honeysuckle extract, centella asiatica extract, goldenrod extract, calendura extract, castor oil, sophora extract, and mastic oil are obtained by hot water extracting each raw material component. You can use it.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다.The natural extract mixture contains 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, and 1% by weight of rosemary extract, based on 100% by weight of the natural extract mixture. ~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight, goldenrod extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~ It may contain 3% by weight, 0.1 to 2% by weight of mastic oil, 10 to 20% by weight of L-menthol, and the remainder of peppermint oil.
자몽종자 추출물은 구취제거를 위하여 첨가하는 것이다. 자몽종자추출물에는 다량의 천연 아스코르빈산, 나린진 및 토코페롤을 함유하고 있어 각종 식품에 대한 항균 및 항산화 작용이 뛰어나다. 비금속성이며, 부식성이 없는 무색무취 천연 유기혼합물로서 환경오염의 원인이 되지 않는다. 천연 추출물 혼합물 내 자몽 종자 추출물의 함량은 1~3중량%인데, 하한값 미만이면 구취 제거 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Grapefruit seed extract is added to eliminate bad breath. Grapefruit seed extract contains a large amount of natural ascorbic acid, naringin, and tocopherol, and has excellent antibacterial and antioxidant effects on various foods. It is a non-metallic, colorless, odorless, natural organic mixture that is non-corrosive and does not cause environmental pollution. The content of grapefruit seed extract in the natural extract mixture is 1 to 3% by weight. If it is below the lower limit, the bad breath removal function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
녹차 추출물은 호르몬 관련성 치주염을 유발하며 복합 감염을 촉진하는 역할을 하는 세균인 Prevotella intermedia에 대한 효과적인 항균 작용이 보고되어 있으며, 천연 방부제로서의 기능도 보고되어 있다.Green tea extract has been reported to have an effective antibacterial effect against Prevotella intermedia, a bacterium that causes hormone-related periodontitis and promotes complex infections, and has also been reported to function as a natural preservative.
황금(Scutellaria baicalensis George)은 꿀풀과에 속하며, 동아시아 대륙 중국 북부지방 원산으로, 우리나라 각처의 산지에 나고, 지리적으로는 동시베리아, 몽고 중국, 만주에 분포하며, 생약에서의 황금은 뿌리를 말린 것으로 봄 또는 가을에 뿌리를 캐서 겉껍질과 썩은 속을 긁어 버리고 물에 씻어 햇볕에 말린 것이다. 천연 추출물 혼합물 내 황금 추출물의 함량은 1~3중량%인데, 하한값 미만이면 구취 제거 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Gold (Scutellaria baicalensis George) belongs to the Lamiaceae family and is native to the northern part of China on the East Asian continent. It grows in mountainous regions of Korea and is geographically distributed in East Siberia, Mongolia, China, and Manchuria. Gold in herbal medicine is the dried root. The roots are dug up in spring or fall, the outer bark and rotten insides are scraped off, washed in water, and dried in the sun. The content of golden extract in the natural extract mixture is 1 to 3% by weight. If it is below the lower limit, the bad breath removal function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
페퍼민트 오일은 구취 제거 기능을 하기 위하여 첨가하는 것이다. 박하의 잎과 줄기를 건조, 증류하여 얻은 기름을 식혀 정제한 연노랑색 액체로 특이한 향기와 신맛이 있어 화장품, 식품, 의약품에 청량제로 쓰인다. Peppermint oil is added to remove bad breath. It is a light yellow liquid obtained by drying and distilling the leaves and stems of mint, cooling and purifying the oil. It has a unique scent and sour taste and is used as a refreshing agent in cosmetics, food, and medicine.
L-맨톨은 박하유와 같이 구취 제거 기능을 하기 위하여 첨가하는 것이다. L-맨톨은 이소프레노이드계열 화합물의 일종이다. 천연에서 가장 일반적인 광학 이성질체는 좌회전성인 L-멘톨로서, 박하유에 존재한다. 소량의 L-멘톨은 시트로넬랄에서 얻어진다. 특유의 산뜻함으로 입안의 청량감을 줄뿐 아니라 구취를 제거하는 기능이 우수하다. 천연 추출물 혼합물 내 L-멘톨의 함량은 10~20중량%인데, 하한값 미만이면 구취 제거 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원 료들의 효능을 약화시킬 수 있다.L-Menthol is added to remove bad breath like peppermint oil. L-Menthol is a type of isoprenoid compound. The most common optical isomer in nature is the left-rotating L-menthol, which is present in peppermint oil. Small amounts of L-menthol are obtained from citronellal. It not only provides a refreshing feeling in the mouth due to its unique refreshing taste, but also has an excellent function of removing bad breath. The content of L-menthol in the natural extract mixture is 10 to 20% by weight. If it is below the lower limit, the bad breath removal function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
카렌듀라(금잔화, Calendula arvensis L.)는 국화과 금잔화속의 식물로서, 그 꽃 추출물은 민간요법으로 서양에서 가장 광범위하게 사용되어온 약용 허브로서, 피부트러블, 수렴, 상처 치유 그리고 항염 등에 사용되어 왔다. 또한 의학적 사용 범위는 항염, 수렴, 항균 그리고 항바이러스에 사용되며 수술 상처에 사용하면 피부의 글리코 프로테인 및 콜라겐 합성을 증가시켜 상처치유를 가속시키는 것으로 알려져 있다. 주요 성분으로는 알파토코페롤(alpha-tocopherol), 클로로겐산(chlorogenic acid), 루틴(lutin), 라이코펜(lycopene) 등이 함유되어 있다. 천연 추출물 혼합물 내 카렌듀라 추출물의 함량은 0.1~2중량%인데, 하한값 미만이면 구취 개선 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Calendula arvensis L. is a plant of the Asteraceae marigold genus, and its flower extract is the most widely used medicinal herb in the West as a folk remedy, and has been used for skin troubles, astringency, wound healing, and anti-inflammatory. In addition, its medical uses include anti-inflammatory, astringent, antibacterial and antiviral properties, and when used on surgical wounds, it is known to accelerate wound healing by increasing glycoprotein and collagen synthesis in the skin. The main ingredients include alpha-tocopherol, chlorogenic acid, lutin, and lycopene. The content of Calendura extract in the natural extract mixture is 0.1 to 2% by weight. If it is below the lower limit, the bad breath improvement function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
상기 천연 추출물 혼합물은 황칠나무 추출물 및 복숭아꽃 추출물을 추가로 포함하는 것일 수 있다. 본 발명에서 황칠나무 추출물 및 복숭아꽃 추출물은 구취 개선 효과가 있다. 상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, 황칠나무 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다The natural extract mixture may further include Hwangchil tree extract and peach blossom extract. In the present invention, Hwangchil tree extract and peach blossom extract have a bad breath improvement effect. The natural extract mixture contains 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, and 1% by weight of rosemary extract, based on 100% by weight of the natural extract mixture. ~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight, goldenrod extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~ It may contain 3% by weight, 0.1~2% by weight of mastic oil, 3~5% by weight of Hwangchil tree extract, 3~5% by weight of peach blossom extract, 10~20% by weight of L-menthol, and the remainder of peppermint oil.
복숭아꽃 추출물은 복숭아꽃으로부터 추출하여 제조된 것으로, 복숭아꽃은 앵도과에 속하며, 전국 산야 및 과수원 등에서 자생 또는 재배하는 낙엽교목인 복숭아(Prunus persica) 나무의 꽃이다.Peach blossom extract is manufactured by extracting from peach blossoms. Peach blossoms belong to the peach family and are the flowers of the peach (Prunus persica) tree, a deciduous tree that grows or is cultivated in fields and orchards across the country.
황칠나무 추출물은 황칠나무의 잎으로부터 추출하여 제조된 것으로, 황칠나무(Dendropanax morbifera Lev)는 두릅나무과 오갈피속의 상록활엽교목으로 높이 15m 이상까지 자라는 한국 고유의 토종나무이다. 어린 가 지는 녹색이며 광택이 있고, 꽃은 6월에 피며, 길이 7~19mm의 열매가 검게 익는다. 최저기온이 영하 2℃ 이상, 연 평균기온이 12~15℃ 이상인 지역에서 자라는 난대성 식물이다. Hwangchil tree extract is manufactured by extracting from the leaves of Hwangchil tree. Hwangchil tree (Dendropanax morbifera Lev) is an evergreen broad-leaved tree of the Araliaceae genus and is a native Korean tree that grows to a height of more than 15m. Young branches are green and shiny, flowers bloom in June, and fruits 7 to 19 mm long ripen black. It is a subtropical plant that grows in areas where the minimum temperature is above -2℃ and the average annual temperature is above 12~15℃.
상기 복숭아꽃 추출물 및 황칠나무 추출물은 각각 복숭아꽃, 황칠나무를 에탄올 추출하여 얻은 복숭아꽃 에탄올 추출물 및 황칠나무 에탄올 추출물이다. 본 발명에서 복숭아꽃 에탄올 추출물 및 황칠나무 에탄올 추출물은 구취 개선 효과가 있다. 천연 추출물 혼합물 100중량% 중 황칠나무 에탄올 추출물 3~5중량% 및 복숭아꽃 에탄올 추출물 3~5중량%를 포함하는 것이 바람직하다.The peach blossom extract and Hwangchil tree extract are peach blossom ethanol extract and Hwangchil tree ethanol extract obtained by ethanol extracting peach blossom and Hwangchil tree, respectively. In the present invention, the ethanol extract of peach blossom and the ethanol extract of Hwangchil tree have a bad breath improvement effect. It is preferable to include 3 to 5% by weight of Hwangchil tree ethanol extract and 3 to 5% by weight of peach blossom ethanol extract in 100% by weight of the natural extract mixture.
상기 황칠나무 에탄올 추출물 및 복숭아꽃 에탄올 추출물의 제조 방법은 다음과 같다: 황칠나무 또는 복숭아꽃 100중량부에 대해 에탄올 100~500중량부를 첨가하고, 20~50℃에서 20~30시간 교반하여 추출한 후, 여과하여 제조한다. 이 때 상기 에탄올은 시판되는 소주를 사용할 수 있으며, 에탄올의 농도는 제한되지 않는다.The method for producing the Hwangchil tree ethanol extract and the peach blossom ethanol extract is as follows: Add 100 to 500 parts by weight of ethanol to 100 parts by weight of Hwangchil tree or peach blossom, and extract by stirring at 20 to 50°C for 20 to 30 hours. , manufactured by filtration. At this time, the ethanol can be commercially available soju, and the concentration of ethanol is not limited.
상기 치약 조성물은 천연 추출물 혼합물과 함께, 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함한다. 바람직하게는, 치약 조성물 100중량% 중 천연 추출물 혼합물 1~5 중량%, 이산화규소 5~15 중량%, 피리독신 염산염 0.01~0.05 중량%, 일불소인산나트륨 0.1~1 중량%, 피로인산나트륨 0.1~1 중량%, 히드록시아파타이트 0.1~1 중량%, 자일리톨 0,1~1 중량%, 글리세린 5~10 중량%, 셀룰로오스검 1~3 중량%, 염화나트륨 0.1~1 중량%, 시트르산 0.01~0.1 중량%, 코코일글루타민산나트륨 1~5 중량%, 소르비톨액 40~60 중량% 및 나머지 물을 포함한다.The toothpaste composition includes a mixture of natural extracts, silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water. Includes. Preferably, in 100% by weight of the toothpaste composition, 1 to 5% by weight of natural extract mixture, 5 to 15% by weight of silicon dioxide, 0.01 to 0.05% by weight of pyridoxine hydrochloride, 0.1 to 1% by weight of sodium monofluorophosphate, and 0.1 to 0.1% by weight of sodium pyrophosphate. 1% by weight, hydroxyapatite 0.1~1% by weight, xylitol 0.1~1% by weight, glycerin 5~10% by weight, cellulose gum 1~3% by weight, sodium chloride 0.1~1% by weight, citric acid 0.01~0.1% by weight , 1 to 5% by weight of sodium cocoyl glutamate, 40 to 60% by weight of sorbitol solution, and the remaining water.
상기 치약 조성물은 치아미백제를 추가로 포함할 수 있으며, 상기 치아미백제는 아염소산 금속, 과탄산염 및 과산화산으로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것일 수 있다. 상기 치약 미백제는 전체 치약 조성물 중 1~10중량%로 포함될 수 있다.The toothpaste composition may further include a tooth whitening agent, and the tooth whitening agent may be composed of one or more selected from the group consisting of metal chlorite, percarbonate, and peroxy acid. The toothpaste whitening agent may be included in 1 to 10% by weight of the total toothpaste composition.
이하 본원을 실시예 및 실험예를 통하여 보다 상세하게 설명한다. 그러나 이들 실시예 및 시험예는 본 발명을 예시적으로 설명하기 위한 것으로 본원의 범위가 이들 실시예 및 시험예에 한정되는 것은 아니다.Hereinafter, the present application will be described in more detail through examples and experimental examples. However, these examples and test examples are for illustrative purposes only and the scope of the present application is not limited to these examples and test examples.
실시예 1Example 1
자몽 종자 추출물 2 중량%, 녹차 추출물 20 중량%, 프로폴리스 추출물 0.5 중량%, 캐모마일 추출물 3 중량%, 로즈마리 추출물 2 중량%, 금은화 추출물 0.5 중량%, 병풀 추출물 2 중량%, 황금 추출물 2 중량%, 카렌듀라 추출물 0.1 중량%, 피마자 오일 1 중량%, 고삼 추출물 2 중량%, 매스틱 오일 0.5 중량%, L-멘톨 15 중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조한다. 상기 천연 추출물 혼합물 5 중량%, 이산화규소 10 중량%, 피리독신 염산염 0.01 중량%, 일불소인산나트륨 0.1 중량%, 피로인산나트륨 0.1 중량%, 히드록시아파타이트 0.5 중량%, 자일리톨 0.2 중량%, 글리세린 5 중량%, 셀룰로오스검 2 중량%, 염화나트륨 0.1 중량%, 시트르산 0.05 중량%, 코코일글루타민산나트륨 3 중량%, 소르비톨액 50 중량% 및 나머지 물을 포함하는 치약 조성물을 제조한다.Grapefruit seed extract 2% by weight, green tea extract 20% by weight, propolis extract 0.5% by weight, chamomile extract 3% by weight, rosemary extract 2% by weight, honeysuckle extract 0.5% by weight, centella asiatica extract 2% by weight, golden extract 2% by weight, A natural extract mixture containing 0.1% by weight of calendura extract, 1% by weight of castor oil, 2% by weight of sophora extract, 0.5% by weight of mastic oil, 15% by weight of L-menthol and the remainder peppermint oil is prepared. 5% by weight of the natural extract mixture, 10% by weight of silicon dioxide, 0.01% by weight of pyridoxine hydrochloride, 0.1% by weight of sodium monofluorophosphate, 0.1% by weight of sodium pyrophosphate, 0.5% by weight of hydroxyapatite, 0.2% by weight of xylitol, 5% by weight of glycerin % by weight, 2% by weight of cellulose gum, 0.1% by weight of sodium chloride, 0.05% by weight of citric acid, 3% by weight of sodium cocoyl glutamate, 50% by weight of sorbitol solution, and the remaining water.
실시예 2Example 2
실시예 1에 있어서, 자몽 종자 추출물 2 중량%, 녹차 추출물 20 중량%, 프로폴리스 추출물 0.5 중량%, 캐모마일 추출물 3 중량%, 로즈마리 추출물 2 중량%, 금은화 추출물 0.5 중량%, 병풀 추출물 2 중량%, 황금 추출물 2 중량%, 카렌듀라 추출물 0.1 중량%, 피마자 오일 1 중량%, 고삼 추출물 2 중량%, 매스틱 오일 0.5 중량%, L-멘톨 15 중량%. 복숭아꽃 에탄올 추출물 4중량%, 황칠나무 에탄올 추출물 4중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight of grapefruit seed extract, 20% by weight of green tea extract, 0.5% by weight of propolis extract, 3% by weight of chamomile extract, 2% by weight of rosemary extract, 0.5% by weight of honeysuckle extract, 2% by weight of Centella asiatica extract, 2% by weight of golden extract, 0.1% by weight of calendura extract, 1% by weight of castor oil, 2% by weight of sophora extract, 0.5% by weight of mastic oil, 15% by weight of L-menthol. A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 4% by weight of peach blossom ethanol extract, 4% by weight of Hwangchil tree ethanol extract, and the remaining peppermint oil was prepared.
실시예 3Example 3
실시예 1에 있어서, 자몽 종자 추출물 2 중량%, 녹차 추출물 20 중량%, 프로폴리스 추출물 0.5 중량%, 캐모마일 추출물 3 중량%, 로즈마리 추출물 2 중량%, 금은화 추출물 0.5 중량%, 병풀 추출물 2 중량%, 황금 추출물 2 중량%, 카렌듀라 추출물 0.1 중량%, 피마자 오일 1 중량%, 고삼 추출물 2 중량%, 매스틱 오일 0.5 중량%, L-멘톨 15 중량%. 복숭아꽃 에탄올 추출물 8중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight of grapefruit seed extract, 20% by weight of green tea extract, 0.5% by weight of propolis extract, 3% by weight of chamomile extract, 2% by weight of rosemary extract, 0.5% by weight of honeysuckle extract, 2% by weight of Centella asiatica extract, 2% by weight of golden extract, 0.1% by weight of calendura extract, 1% by weight of castor oil, 2% by weight of sophora extract, 0.5% by weight of mastic oil, 15% by weight of L-menthol. A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 8% by weight of peach blossom ethanol extract and the remaining peppermint oil was prepared.
실시예 4Example 4
실시예 1에 있어서, 자몽 종자 추출물 2 중량%, 녹차 추출물 20 중량%, 프로폴리스 추출물 0.5 중량%, 캐모마일 추출물 3 중량%, 로즈마리 추출물 2 중량%, 금은화 추출물 0.5 중량%, 병풀 추출물 2 중량%, 황금 추출물 2 중량%, 카렌듀라 추출물 0.1 중량%, 피마자 오일 1 중량%, 고삼 추출물 2 중량%, 매스틱 오일 0.5 중량%, L-멘톨 15 중량%. 황칠나무 에탄올 추출물 8중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight of grapefruit seed extract, 20% by weight of green tea extract, 0.5% by weight of propolis extract, 3% by weight of chamomile extract, 2% by weight of rosemary extract, 0.5% by weight of honeysuckle extract, 2% by weight of Centella asiatica extract, 2% by weight of golden extract, 0.1% by weight of calendura extract, 1% by weight of castor oil, 2% by weight of sophora extract, 0.5% by weight of mastic oil, 15% by weight of L-menthol. A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 8% by weight of Hwangchil tree ethanol extract and the remaining peppermint oil was prepared.
비교예 1Comparative Example 1
실시예 1에 있어서, 천연추출물 혼합물 대신에 항균제로 알려진 이소프로필메틸페놀, 사이클로헥시딘, 세틸피리디늄 클로라이드, 트키를로산으로 이루어진 항균제를 사용한 것을 제외하고, 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, a toothpaste composition was prepared in the same manner as in Example 1, except that an antibacterial agent consisting of isopropylmethylphenol, cyclohexidine, cetylpyridinium chloride, and cyclohexane, known as antibacterial agents, was used instead of the natural extract mixture. manufactures.
실험예 1: 구취 개선 효과 확인Experimental Example 1: Confirmation of bad breath improvement effect
상기 실시예 및 비교예의 치약 조성물을 이용하여 구취 개선 효과를 확인하였다. 구취가 있는 환자 50명을 대상으로 상기 치약 조성물을 하루에 3번씩 3주동안 사용하게 하여, 구취 개선 여부를 1점~10점으로 평가하여 확인하였다. The effect of improving bad breath was confirmed using the toothpaste compositions of the above examples and comparative examples. Fifty patients with bad breath were asked to use the toothpaste composition three times a day for three weeks, and the improvement in bad breath was evaluated on a scale of 1 to 10.
상기 표에 나타낸 바와 같이, 실시예 1 내지 4의 치약 조성물은 구취 개선 효과가 있는 것을 확인하였으며, 특히 황칠나무 추출물 및 복숭아꽃 추출물을 모두 포함하는 실시예 2의 치약 조성물의 구취 개선 효과가 우수한 것을 확인하였다.As shown in the table above, it was confirmed that the toothpaste compositions of Examples 1 to 4 had a bad breath improvement effect, and in particular, the toothpaste composition of Example 2 containing both Hwangchil tree extract and peach blossom extract had an excellent bad breath improvement effect. Confirmed.
실험예 2: 황화합물 제거 평가Experimental Example 2: Sulfur compound removal evaluation
음식 냄새의 원인이 되는 황화합물 제거 여부를 평가하였다. 마늘을 포함한 용액을 제조하였다. 성인 20명에게 마늘 용액을 1분간 입에 머금게 하고, halimeter를 이용하여 구취를 측정하였다. 이어서, 상기 실시예 및 비교예의 치약 조성물을 이용하여 3분간 양치하고, 30분 경과후 다시 구취를 측정하여 20명의 평균을 계산하였다. 그 결과를 아래 표에 나타낸다.The removal of sulfur compounds that cause food odor was evaluated. A solution containing garlic was prepared. Twenty adults were asked to hold garlic solution in their mouths for 1 minute, and bad breath was measured using a halimeter. Next, teeth were brushed for 3 minutes using the toothpaste compositions of the examples and comparative examples, and after 30 minutes, bad breath was measured again and the average of 20 people was calculated. The results are shown in the table below.
상기 표에 나타낸 바와 같이, 실시예 1 내지 4의 치약 조성물은 황화합물 제거 효과가 있는 것을 확인하였으며, 특히 황칠나무 추출물 및 복숭아꽃 추출물을 모두 포함하는 실시예 2의 치약 조성물의 황화합물 제거 효과가 우수한 것을 확인하였다.As shown in the table above, it was confirmed that the toothpaste compositions of Examples 1 to 4 had a sulfur compound removal effect, and in particular, the toothpaste composition of Example 2 containing both Hwangchil tree extract and peach blossom extract had an excellent sulfur compound removal effect. Confirmed.
실험예 3: 세정도 및 사용감 평가Experimental Example 3: Evaluation of cleanliness and feeling of use
상기 실시예 및 비교예의 치약 조성물을 이용하여 세정도 및 사용감을 평가하였다. 20명의 성인에게 하루에 3번씩 3주동안 사용하게 하여, 세정도 및 사용감을 1점~10점으로 평가하여 확인하였다.The degree of cleansing and feeling of use were evaluated using the toothpaste compositions of the above Examples and Comparative Examples. Twenty adults were asked to use the product three times a day for three weeks, and the degree of cleansing and feeling of use were evaluated on a scale of 1 to 10.
상기 표에 나타낸 바와 같이, 실시예 1 내지 4의 치약 조성물은 세정도 및 사용감이 우수한 것을 확인하였으며, 특히 황칠나무 추출물 및 복숭아꽃 추출물을 모두 포함하는 실시예 2의 치약 조성물의 세정도 및 사용감이 우수한 것을 확인하였다.As shown in the table above, it was confirmed that the toothpaste compositions of Examples 1 to 4 were excellent in cleanliness and feeling of use, and in particular, the degree of cleansing and feeling of use of the toothpaste composition of Example 2 containing both Hwangchil tree extract and peach blossom extract were excellent. It was confirmed to be excellent.
Claims (6)
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, 황칠나무 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 포함하는 것인, 구취 예방 또는 개선용 치약 조성물.Contains natural extract mixture, silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water;
The natural extract mixture contains 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, and 1% by weight of rosemary extract, based on 100% by weight of the natural extract mixture. ~3% by weight, honeysuckle extract 0.1~2% by weight, centella asiatica extract 1~3% by weight, goldenrod extract 1~3% by weight, calendura extract 0.1~2% by weight, castor oil 0.1~2% by weight, sophora extract 1~ 3% by weight, 0.1 to 2% by weight of mastic oil, 3 to 5% by weight of Hwangchil tree extract, 3 to 5% by weight of peach blossom extract, 10 to 20% by weight of L-menthol, and the remainder of peppermint oil. Toothpaste composition for prevention or improvement.
황칠나무를 에탄올로 가열하여 추출하고, 여과하여 황칠나무 추출물을 제조하는 단계;
천연 추출물 혼합물 100중량%에 대해 자몽 종자 추출물 1~3 중량%, 녹차 추출물 20~30 중량%, 프로폴리스 추출물 0.1~1 중량%, 캐모마일 추출물 1~3 중량%, 로즈마리 추출물 1~3 중량%, 금은화 추출물 0.1~2 중량%, 병풀 추출물 1~3 중량%, 황금 추출물 1~3 중량%, 카렌듀라 추출물 0.1~2 중량%, 피마자 오일 0.1~2 중량%, 고삼 추출물 1~3 중량%, 매스틱 오일 0.1~2 중량%, 황칠나무 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~20 중량% 및 나머지 페퍼민트 오일을 혼합하여 천연 추출물 혼합물을 제조하는 단계;
상기 천연 추출물 혼합물과 이산화규소, 피리독신 염산염, 일불소인산나트륨, 피로인산나트륨, 히드록시아파타이트, 자일리톨, 글리세린, 셀룰로오스검, 염화나트륨, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 혼합하는 단계;를 포함하는, 구취 예방 또는 개선용 치약 조성물의 제조 방법.Preparing peach blossom extract by heating and extracting peach blossoms with ethanol and filtering them;
Preparing a Hwangchil tree extract by heating and filtering the Hwangchil tree with ethanol;
Based on 100% by weight of natural extract mixture, 1-3% by weight of grapefruit seed extract, 20-30% by weight of green tea extract, 0.1-1% by weight of propolis extract, 1-3% by weight of chamomile extract, 1-3% by weight of rosemary extract, Honeysuckle extract 0.1~2% by weight, Centella asiatica extract 1~3% by weight, Golden extract 1~3% by weight, Calendura extract 0.1~2% by weight, Castor oil 0.1~2% by weight, Sophora extract 1~3% by weight, Plum Preparing a natural extract mixture by mixing 0.1 to 2% by weight of stick oil, 3 to 5% by weight of Hwangchil tree extract, 3 to 5% by weight of peach blossom extract, 10 to 20% by weight of L-menthol, and the remaining peppermint oil;
Mixing the natural extract mixture with silicon dioxide, pyridoxine hydrochloride, sodium monofluorophosphate, sodium pyrophosphate, hydroxyapatite, xylitol, glycerin, cellulose gum, sodium chloride, citric acid, sodium cocoyl glutamate, sorbitol solution and water; A method of producing a toothpaste composition for preventing or improving bad breath, comprising:
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