KR102622954B1 - Toothpaste composition for improving or preventing gingivitis and periodontitis - Google Patents
Toothpaste composition for improving or preventing gingivitis and periodontitis Download PDFInfo
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- KR102622954B1 KR102622954B1 KR1020230122024A KR20230122024A KR102622954B1 KR 102622954 B1 KR102622954 B1 KR 102622954B1 KR 1020230122024 A KR1020230122024 A KR 1020230122024A KR 20230122024 A KR20230122024 A KR 20230122024A KR 102622954 B1 KR102622954 B1 KR 102622954B1
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- extract
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- natural
- periodontitis
- mixture
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Classifications
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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Abstract
본 발명은 치은염 및 치주염 개선 또는 예방 효과가 있는 치약 조성물에 관한 것이다. 본 발명은 천연 추출물 혼합물, 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 알로에 추출물, 자몽 종자 추출물, 녹차 추출물, 금은화 추출물, 강황 추출물, 올리브 오일, 감초 추출물, 카렌듀라 추출물, 프로폴리스 추출물, 세이지 추출물, 황금 추출물, 캐모마일 추출물, 죽염, 유칼립투스 오일, 페퍼민트 오일 및 L-멘톨을 포함하는 것인, 치은염 및 치주염 개선 또는 예방용 치약 조성물을 제공한다.The present invention relates to a toothpaste composition that has the effect of improving or preventing gingivitis and periodontitis. The present invention includes a natural extract mixture, dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution and water, and the natural extract mixture includes aloe extract. Contains grapefruit seed extract, green tea extract, honeysuckle extract, turmeric extract, olive oil, licorice extract, calendura extract, propolis extract, sage extract, goldenrod extract, chamomile extract, bamboo salt, eucalyptus oil, peppermint oil and L-menthol. Provided is a toothpaste composition for improving or preventing gingivitis and periodontitis.
Description
본 발명은 치은염 및 치주염 개선 또는 예방 효과가 있는 치약 조성물에 관한 것이다.The present invention relates to a toothpaste composition that has the effect of improving or preventing gingivitis and periodontitis.
치약은 치아를 청결하게 하고, 치아의 표면에 달라붙은 불순물을 제거할 목적으로 칫솔에 묻혀 사용하는 분말이나 크림 또는 액상의 약물성 복합물질을 일컫는데, 소독작용, 치석용해작용, 냄새감퇴작용 및 충치나 치조농루 등의 예방 또는 치료에 도움을 준다.Toothpaste refers to a powder, cream, or liquid drug compound used on a toothbrush for the purpose of cleaning teeth and removing impurities stuck to the surface of teeth. It has disinfecting, tartar-dissolving, odor-reducing and It helps prevent or treat cavities or pyorrhea.
이와 같은 치약은 치아에 부착된 치구, 치석 따위를 제거하며 치아면에 본래의 광택을 부여하는 역할을 하는 연마제와, 배합된 계면활성제의 작용으로 사용시의 계면장력을 저하시켜 칫솔질의 청소효과를 높이고 배합되어 있는 약효제의 분산, 침투성을 도와주는 역할을 하는 발포제와, 치약에 습기와 크림상을 주기 위하여 치약이 공기 중에 접촉하여 고체화되는 것을 방지하는 역할을 하는 습윤제와, 치약의 고체성분과 액체성분의 분리를 방지하는 역할을 하는 점결제와, 충치예방, 농루예방, 치아미백, 치석의 침착방지, 구취예방 등의 효과를 증강하기위 한 약효성분, 착색제 및 보존제 등이 함유된다.This kind of toothpaste improves the cleaning effect of toothbrushing by lowering the interfacial tension during use through the action of an abrasive that removes plaque and tartar attached to the teeth and gives the original gloss to the tooth surface, and a blended surfactant. A foaming agent that helps the dispersion and penetration of the mixed medicinal agent, a humectant that prevents the toothpaste from solidifying on contact with the air to give the toothpaste moisture and a creamy appearance, and the solid ingredients and liquid of the toothpaste. It contains a binder that acts to prevent separation of ingredients, and medicinal ingredients, colorants, and preservatives to enhance the effects of preventing cavities, preventing pyorrhea, whitening teeth, preventing deposition of tartar, and preventing bad breath.
한편, 구강에 발생하는 각종 질환은 구강 내에 생성되는 플라그 및 수많은 세균에 의해 유발되는데, 플라그는 스트렙토코커스 뮤탄스(Streptococcus mutans) 등과 같이 구강 내에 서식하는 세균에 의하여 만들어지는 점착성 물질이며, 이는 치아의 표면과 잇몸에 부착된 끈적끈적한 막으로, 구강 세균이 포도당 중합체인 덱스트란의 그 물망 속에 갇혀 있는 치면 세균막으로 구성되며 치아 및 그 주변조직에 발생되는 중요한 질병인 충치, 치석 및 잇몸질환의 주요발병 원인으로 알려져 있다. Meanwhile, various diseases that occur in the oral cavity are caused by plaque and numerous bacteria generated in the oral cavity. Plaque is a sticky substance produced by bacteria living in the oral cavity, such as Streptococcus mutans, and it is a sticky substance that acts on the teeth. It is a sticky film attached to the surface and gums, and consists of dental biofilm, in which oral bacteria are trapped in a mesh of dextran, a glucose polymer. It is a major cause of cavities, tartar, and gum disease, which are important diseases that occur in teeth and surrounding tissues. It is known to be the cause.
또한, 상기 플라그는 구강 내 타액중 칼슘, 마그네슘 및 인 등의 성분과 결합하여 난용성 염을 형성하여 치아와 유사한 경도를 가진 치석으로 변환되는데, 이렇게 발생되는 치석은 잇몸과 치아의 경계면을 파고들어 양치시 쉽게 출혈을 유발시키고 또한 구강 내 세균에 의한 염증을 유발시켜서 치은염 및 치주질환을 발생시킨다.In addition, the plaque combines with components such as calcium, magnesium, and phosphorus in oral saliva to form poorly soluble salts, which are converted into tartar with a hardness similar to that of teeth. The tartar thus generated penetrates into the interface between the gums and teeth. It easily causes bleeding when brushing teeth and also causes inflammation caused by bacteria in the oral cavity, resulting in gingivitis and periodontal disease.
본 발명은 치은염 및 치주염 개선 또는 예방 효과가 있으며, 친환경 추출물을 포함하는 치약 조성물을 제공하는 것을 목적으로 한다.The purpose of the present invention is to provide a toothpaste composition containing an eco-friendly extract that has the effect of improving or preventing gingivitis and periodontitis.
본 개시의 목적들은 이상에서 언급한 목적으로 제한되지 않으며, 언급되지 않은 본 개시의 다른 목적 및 장점들은 하기의 설명에 의해서 이해될 수 있고, 본 개시의 실시 예에 의해 보다 분명하게 이해될 것이다. 또한, 본 개시의 목적 및 장점들은 특허 청구 범위에 나타낸 수단 및 그 조합에 의해 실현될 수 있음을 쉽게 알 수 있을 것이다.The objects of the present disclosure are not limited to the purposes mentioned above, and other objects and advantages of the present disclosure that are not mentioned can be understood by the following description and will be more clearly understood by the examples of the present disclosure. Additionally, it will be readily apparent that the objects and advantages of the present disclosure can be realized by the means and combinations thereof indicated in the patent claims.
본 발명은 천연 추출물 혼합물, 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 알로에 추출물, 자몽 종자 추출물, 녹차 추출물, 금은화 추출물, 강황 추출물, 올리브 오일, 감초 추출물, 카렌듀라 추출물, 프로폴리스 추출물, 세이지 추출물, 황금 추출물, 캐모마일 추출물, 죽염, 유칼립투스 오일, 페퍼민트 오일 및 L-멘톨을 포함하는 것인, 치은염 및 치주염 개선 또는 예방용 치약 조성물을 제공한다.The present invention includes a natural extract mixture, dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution and water, and the natural extract mixture includes aloe extract. Contains grapefruit seed extract, green tea extract, honeysuckle extract, turmeric extract, olive oil, licorice extract, calendura extract, propolis extract, sage extract, goldenrod extract, chamomile extract, bamboo salt, eucalyptus oil, peppermint oil and L-menthol. Provided is a toothpaste composition for improving or preventing gingivitis and periodontitis.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다. The natural extract mixture contains 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, and 2-4% by weight of turmeric extract, based on 100% by weight of the natural extract mixture. 4% by weight, olive oil 2~4% by weight, licorice extract 2~4% by weight, calendura extract 3~5%, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4 % by weight, it may include 2-4% by weight of chamomile extract, 1-3% by weight of bamboo salt, 2-4% by weight of eucalyptus oil, 10-15% by weight of L-menthol, and the remainder of peppermint oil.
상기 천연 추출물 혼합물은 갓 추출물 및 복숭아꽃 추출물을 추가로 포함하는 것일 수 있다.The natural extract mixture may further include mustard extract and peach blossom extract.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, 갓 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다.The natural extract mixture contains 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, and 2-4% by weight of turmeric extract, based on 100% by weight of the natural extract mixture. 4% by weight, olive oil 2~4% by weight, licorice extract 2~4% by weight, calendura extract 3~5%, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4 Weight %, chamomile extract 2~4% by weight, bamboo salt 1~3% by weight, eucalyptus oil 2~4% by weight, mustard leaf extract 3~5% by weight, peach blossom extract 3~5% by weight, L-menthol 10~15% by weight % and the remainder may include peppermint oil.
또한 본 발명은 알로에 추출물, 자몽 종자 추출물, 녹차 추출물, 금은화 추출물, 강황 추출물, 올리브 오일, 감초 추출물, 카렌듀라 추출물, 프로폴리스 추출물, 세이지 추출물, 황금 추출물, 캐모마일 추출물, 죽염, 유칼립투스 오일, 페퍼민트 오일 및 L-멘톨을 혼합하여 천연 추출물 혼합물을 제조하는 단계; 상기 천연 추출물 혼합물과 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 혼합하는 단계;를 포함하는, 치은염 및 치주염 개선 또는 예방용 치약 조성물의 제조 방법을 제공한다.In addition, the present invention provides aloe extract, grapefruit seed extract, green tea extract, honeysuckle extract, turmeric extract, olive oil, licorice extract, calendura extract, propolis extract, sage extract, goldenrod extract, chamomile extract, bamboo salt, eucalyptus oil, and peppermint oil. and L-menthol to prepare a natural extract mixture; Improving gingivitis and periodontitis, including mixing the natural extract mixture with dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution, and water. Alternatively, a method for producing a preventive toothpaste composition is provided.
복숭아꽃을 에탄올로 가열하여 추출하고, 여과하여 복숭아꽃 추출물을 제조하는 단계; 갓을 에탄올로 가열하여 추출하고, 여과하여 갓 추출물을 제조하는 단계;를 추가로 포함하며, 상기 천연추출물 혼합물을 제조하는 단계는, 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, 상기 갓 추출물 3~5중량%, 상기 복숭아꽃 추출물 3~5중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 혼합하여 제조하는 단계일 수 있다.Preparing peach blossom extract by heating and extracting peach blossoms with ethanol and filtering them; It further includes the step of extracting the mustard by heating it with ethanol and filtering it to prepare a mustard extract, wherein the step of preparing the natural extract mixture includes 1 to 3% by weight of aloe extract based on 100% by weight of the natural extract mixture, Grapefruit seed extract 1-3% by weight, green tea extract 1-3% by weight, honeysuckle extract 2-4% by weight, turmeric extract 2-4% by weight, olive oil 2-4% by weight, licorice extract 2-4% by weight, karen Dura extract 3~5% by weight, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4% by weight, chamomile extract 2~4% by weight, bamboo salt 1~3% by weight, eucalyptus oil 2% It may be a step of mixing ~4% by weight, 3-5% by weight of the mustard extract, 3-5% by weight of the peach blossom extract, 10-15% by weight of L-menthol, and the remaining peppermint oil.
본 발명은 치은염 및 치주염 개선 또는 예방 효과가 있으며, 친환경 천연 추출물을 포함하는 치약 조성물을 제공할 수 있다.The present invention has the effect of improving or preventing gingivitis and periodontitis and can provide a toothpaste composition containing eco-friendly natural extracts.
본 발명은 천연 추출물 혼합물, 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함하며, 상기 천연 추출물 혼합물은 알로에 추출물, 자몽 종자 추출물, 녹차 추출물, 금은화 추출물, 강황 추출물, 올리브 오일, 감초 추출물, 카렌듀라 추출물, 프로폴리스 추출물, 세이지 추출물, 황금 추출물, 캐모마일 추출물, 죽염, 유칼립투스 오일, 페퍼민트 오일 및 L-멘톨을 포함하는 것인, 치은염 및 치주염 개선 또는 예방용 치약 조성물을 제공한다.The present invention includes a natural extract mixture, dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution and water, and the natural extract mixture includes aloe extract. Contains grapefruit seed extract, green tea extract, honeysuckle extract, turmeric extract, olive oil, licorice extract, calendura extract, propolis extract, sage extract, goldenrod extract, chamomile extract, bamboo salt, eucalyptus oil, peppermint oil and L-menthol. Provided is a toothpaste composition for improving or preventing gingivitis and periodontitis.
치은염이란, 구강점막의 일부인 치은에 발생한 염증을 의미한다. 구강점막의 다른 부위에 동시에 존재하는 경우는 구내염이라고 하고, 치은 가장자리에 생기는 염증은 치육염이라고 한다.Gingivitis refers to inflammation that occurs in the gingiva, which is part of the oral mucosa. When it exists simultaneously in different parts of the oral mucosa, it is called stomatitis, and when inflammation occurs at the edge of the gingiva, it is called gingivitis.
치주염이란, 치은, 치근막, 치조골에 염증이 있을 경우 각각 치은염, 치근막염, 치조골염이라고 부르는데, 세 조직에서 발생한 염증을 통칭하여 치주염이라 한다.Periodontitis, when there is inflammation in the gingiva, periodontal fascia, and alveolar bone, is called gingivitis, periodontal fasciitis, and alveolar osteitis, respectively. Inflammation occurring in the three tissues is collectively called periodontitis.
본 명세서에서, "예방"이란, 본 발명에 따른 치약 조성물의 사용에 의해 치주염 또는 치은염의 증상의 발생을 억제시키거나 발병을 지연시키는 모든 행위를 의미한다. As used herein, “prevention” refers to all actions that suppress or delay the onset of symptoms of periodontitis or gingivitis by using the toothpaste composition according to the present invention.
본 명세서에서, "개선"이란, 본 발명에 따른 치약 조성물의 사용에 의해 치주염 또는 치은염의 증상을 완화, 감소, 또는 소멸시키는 등 그 증세를 호전시키거나 이롭게 변경하는 모든 행위를 의미한다.In this specification, “improvement” means any action that improves or beneficially changes the symptoms of periodontitis or gingivitis, such as alleviating, reducing, or eliminating the symptoms of periodontitis or gingivitis by using the toothpaste composition according to the present invention.
상기 알로에 추출물, 자몽 종자 추출물, 녹차 추출물, 금은화 추출물, 강황 추출물, 올리브 오일, 감초 추출물, 카렌듀라 추출물, 프로폴리스 추출물, 세이지 추출물, 황금 추출물, 캐모마일 추출물은 각 원료 성분들을 열수 추출한 열수 추출물을 사용할 수 있다.The aloe extract, grapefruit seed extract, green tea extract, honeysuckle extract, turmeric extract, olive oil, licorice extract, calendura extract, propolis extract, sage extract, goldenrod extract, and chamomile extract can be used as hot water extracts obtained by hot water extracting each raw material ingredient. You can.
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다. The natural extract mixture contains 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, and 2-4% by weight of turmeric extract, based on 100% by weight of the natural extract mixture. 4% by weight, olive oil 2~4% by weight, licorice extract 2~4% by weight, calendura extract 3~5%, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4 % by weight, it may include 2-4% by weight of chamomile extract, 1-3% by weight of bamboo salt, 2-4% by weight of eucalyptus oil, 10-15% by weight of L-menthol, and the remainder of peppermint oil.
알로에 추출물은 스포델루스과(Asphodelaceae)에 속하는 다년생 관목으로 장미와 같은 패턴으로 줄기를 둘러싼 잎이 있고, 중앙에는 꽃이 자라는 알로에베라의 추출물이다. 알로에 추출물은 치주염 또는 치은염의 개선 또는 예방을 위해 첨가하는 것이다. 천연 추출물 혼합물 내 알로에 추출물의 함량은 1~3중량%인데, 하한값 미만이면 치주염 또는 치은염의 개선 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Aloe extract is an extract of Aloe vera, a perennial shrub belonging to the Asphodelaceae family, with leaves surrounding the stem in a rose-like pattern and flowers growing in the center. Aloe extract is added to improve or prevent periodontitis or gingivitis. The content of aloe extract in the natural extract mixture is 1 to 3% by weight. If it is below the lower limit, the improvement function of periodontitis or gingivitis may be weakened, and if it is above the upper limit, it may weaken the efficacy of the raw materials added together.
자몽종자추출물은 치주염 또는 치은염 개선 효과 및 구취제거를 위하여 첨가하는 것이다. 자몽종자추출물에는 다량의 천연 아스코르빈산, 나린진 및 토코페롤을 함유하고 있어 각종 식품에 대한 항균 및 항산화 작용이 뛰어나다. 비금속성이며, 부식성이 없는 무색무취 천연 유기혼합물로서 환경오염의 원인이 되지 않는다. 천연 추출물 혼합물 내 자몽 종자 추출물의 함량은 1~3중량%인데, 하한값 미만이면 구취 제거 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Grapefruit seed extract is added to improve periodontitis or gingivitis and remove bad breath. Grapefruit seed extract contains a large amount of natural ascorbic acid, naringin, and tocopherol, and has excellent antibacterial and antioxidant effects on various foods. It is a non-metallic, colorless, odorless, natural organic mixture that is non-corrosive and does not cause environmental pollution. The content of grapefruit seed extract in the natural extract mixture is 1 to 3% by weight. If it is below the lower limit, the bad breath removal function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
황금(Scutellaria baicalensis George)은 꿀풀과에 속하며, 동아시아 대륙 중국 북부지방 원산으로, 우리나라 각처의 산지에 나고, 지리적으로는 동시베리아, 몽고 중국, 만주에 분포하며, 생약에서의 황금은 뿌리를 말린 것으로 봄 또는 가을에 뿌리를 캐서 겉껍질과 썩은 속을 긁어 버리고 물에 씻어 햇볕에 말린 것이다. 천연 추출물 혼합물 내 황금 추출물의 함량은 2~4중량%인데, 하한값 미만이면 치은염 또는 치주염 개선 또는 예방 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Gold (Scutellaria baicalensis George) belongs to the Lamiaceae family and is native to the northern part of China on the East Asian continent. It grows in mountainous regions of Korea and is geographically distributed in East Siberia, Mongolia, China, and Manchuria. Gold in herbal medicine is the dried root. The roots are dug up in spring or fall, the outer bark and rotten insides are scraped off, washed in water, and dried in the sun. The content of golden extract in the natural extract mixture is 2 to 4% by weight. If it is below the lower limit, the function of improving or preventing gingivitis or periodontitis may be weakened, and if it is above the upper limit, it may weaken the efficacy of the raw materials added together.
녹차 추출물은 호르몬 관련성 치주염을 유발하며 복합 감염을 촉진하는 역할을 하는 세균인 Prevotella intermedia에 대한 효과적인 항균 작용이 보고되어 있으며, 천연 방부제로서의 기능도 보고되어 있다.Green tea extract has been reported to have an effective antibacterial effect against Prevotella intermedia, a bacterium that causes hormone-related periodontitis and promotes complex infections, and has also been reported to function as a natural preservative.
페퍼민트 오일은 구취 제거 기능을 하기 위하여 첨가하는 것이다. 박하의 잎과 줄기를 건조, 증류하여 얻은 기름을 식혀 정제한 연노랑색 액체로 특이한 향기와 신맛이 있어 화장품, 식품, 의약품에 청량제로 쓰인다. Peppermint oil is added to remove bad breath. It is a light yellow liquid obtained by drying and distilling the leaves and stems of mint, cooling and purifying the oil. It has a unique scent and sour taste and is used as a refreshing agent in cosmetics, food, and medicine.
L-맨톨은 박하유와 같이 구취 제거 기능을 하기 위하여 첨가하는 것이다. L-맨톨은 이소프레노이드계열 화합물의 일종이다. 천연에서 가장 일반적인 광학 이성질체는 좌회전성인 L-멘톨로서, 박하유에 존재한다. 소량의 L-멘톨은 시트로넬랄에서 얻어진다. 특유의 산뜻함으로 입안의 청량감을 줄뿐 아니라 구취를 제거하는 기능이 우수하다. 천연 추출물 혼합물 내 L-멘톨의 함량은 10~15중량%인데, 하한값 미만이면 구취 제거 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.L-Menthol is added to remove bad breath like peppermint oil. L-Menthol is a type of isoprenoid compound. The most common optical isomer in nature is the left-rotating L-menthol, which is present in peppermint oil. Small amounts of L-menthol are obtained from citronellal. It not only provides a refreshing feeling in the mouth due to its unique refreshing taste, but also has an excellent function of removing bad breath. The content of L-menthol in the natural extract mixture is 10 to 15% by weight. If it is below the lower limit, the bad breath removal function may be weakened, and if it is above the upper limit, it may weaken the effectiveness of the raw materials added together.
죽염은 세포 생신작용(生新作用)을 하는 대나무와 살균으로 부패를 방지하는 소금을 소성로(furnace)에서 고열로 반복처리함으로써, 이들이 가지고 있는 약효를 최대한 증진시킨 가공소금의 일종이다. 죽염은 치주염 또는 치은염의 개선 또는 예방, 그리고 치약 조성물의 연마 효과를 위해 첨가하는 것이다. 천연 추출물 혼합물 내 죽염의 함량은 1~3중량%인데, 하한값 미만이면 치주염 또는 치은염의 개선 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Bamboo salt is a type of processed salt whose medicinal effects are maximized by repeatedly processing bamboo, which promotes cell renewal, and salt, which prevents decay through sterilization, at high heat in a furnace. Bamboo salt is added to improve or prevent periodontitis or gingivitis, and for the polishing effect of toothpaste compositions. The content of bamboo salt in the natural extract mixture is 1 to 3% by weight. If it is below the lower limit, the improvement function of periodontitis or gingivitis may be weakened, and if it is above the upper limit, it may weaken the efficacy of the raw materials added together.
카렌듀라(금잔화, Calendula arvensis L.)는 국화과 금잔화속의 식물로서, 그 꽃 추출물은 민간요법으로 서양에서 가장 광범위하게 사용되어온 약용 허브로서, 피부트러블, 수렴, 상처 치유 그리고 항염 등에 사용되어 왔다. 또한 의학적 사용 범위는 항염, 수렴, 항균 그리고 항바이러스에 사용되며 수술 상처에 사용하면 피부의 글리코 프로테인 및 콜라겐 합성을 증가시켜 상처치유를 가속시키는 것으로 알려져 있다. 주요 성분으로는 알파토코페롤(alpha-tocopherol), 클로로겐산(chlorogenic acid), 루틴(lutin), 라이코펜(lycopene) 등이 함유되어 있다. 천연 추출물 혼합물 내 카렌듀라 추출물의 함량은 3~5중량%인데, 하한값 미만이면 치주염 또는 치은염의 개선 기능이 약화될 수 있으며, 상한값 초가인 경우 같이 첨가되는 원료들의 효능을 약화시킬 수 있다.Calendula arvensis L. is a plant of the Asteraceae marigold genus, and its flower extract is the most widely used medicinal herb in the West as a folk remedy, and has been used for skin troubles, astringency, wound healing, and anti-inflammatory. In addition, its medical uses include anti-inflammatory, astringent, antibacterial and antiviral properties, and when used on surgical wounds, it is known to accelerate wound healing by increasing glycoprotein and collagen synthesis in the skin. The main ingredients include alpha-tocopherol, chlorogenic acid, lutin, and lycopene. The content of Calendura extract in the natural extract mixture is 3 to 5% by weight. If it is less than the lower limit, the improvement function of periodontitis or gingivitis may be weakened, and if it is above the upper limit, the efficacy of the raw materials added together may be weakened.
상기 천연 추출물 혼합물은 갓 추출물 및 복숭아꽃 추출물을 추가로 포함할 수 있다. 본 발명에서 갓 추출물 및 복숭아꽃 추출물은 치주염 및 치은염 개선 효과가 있다. 상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, 갓 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 포함하는 것일 수 있다.The natural extract mixture may further include mustard extract and peach blossom extract. In the present invention, mustard extract and peach blossom extract are effective in improving periodontitis and gingivitis. The natural extract mixture contains 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, and 2-4% by weight of turmeric extract, based on 100% by weight of the natural extract mixture. 4% by weight, olive oil 2~4% by weight, licorice extract 2~4% by weight, calendura extract 3~5%, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4 Weight %, chamomile extract 2~4% by weight, bamboo salt 1~3% by weight, eucalyptus oil 2~4% by weight, mustard leaf extract 3~5% by weight, peach blossom extract 3~5% by weight, L-menthol 10~15% by weight % and the remainder may include peppermint oil.
갓(Brassica juncea)은 겨자과에 속하는 경엽채소류 중의 하나로서, 갓의 잎은 우리나라에서는 주로 김치의 재료로 식용되고 있고 그 씨는 향신료로 사용되고 있다. 갓 잎은 특유의 매운 맛과 향을 낸다. 갓은 생갓을 이용하거나 끓는 물에 데친 갓을 이용할 수 있다. Gat (Brassica juncea) is one of the leafy vegetables belonging to the mustard family. In Korea, its leaves are mainly eaten as an ingredient in kimchi, and its seeds are used as a spice. Gat leaves have a unique spicy taste and aroma. The mustard can be used raw or blanched in boiling water.
복숭아꽃 추출물은 복숭아꽃으로부터 추출하여 제조된 것으로, 복숭아꽃은 앵도과에 속하며, 전국 산야 및 과수원 등에서 자생 또는 재배하는 낙엽교목인 복숭아(Prunus persica) 나무의 꽃이다.Peach blossom extract is manufactured by extracting from peach blossoms. Peach blossoms belong to the peach family and are the flowers of the peach (Prunus persica) tree, a deciduous tree that grows or is cultivated in mountains and orchards across the country.
상기 갓 추출물 및 복숭아꽃 추출물은 각각 갓, 복숭아꽃을 에탄올 추출하여 얻은 갓 에탄올 추출물 및 복숭아꽃 에탄올 추출물이다. 본 발명에서 갓 에탄올 추출물 및 복숭아꽃 에탄올 추출물은 치주염 및 치은염 개선 효과가 있다. 천연 추출물 혼합물 100중량% 중 갓 에탄올 추출물 3~5중량% 및 복숭아꽃 에탄올 추출물 3~5중량%를 포함하는 것이 바람직하다.The mustard leaf extract and peach blossom extract are respectively obtained by ethanol extracting mustard leaf and peach blossom. In the present invention, fresh ethanol extract and peach blossom ethanol extract are effective in improving periodontitis and gingivitis. It is preferable to include 3 to 5% by weight of fresh ethanol extract and 3 to 5% by weight of peach blossom ethanol extract in 100% by weight of the natural extract mixture.
상기 갓 에탄올 추출물 및 복숭아꽃 에탄올 추출물의 제조 방법은 다음과 같다: 갓 잎 분말 또는 복숭아꽃 분말 100중량부에 대해 에탄올 100~500중량부를 첨가하고, 20~50℃에서 20~30시간 교반하여 추출한 후, 여과하여 제조한다.The method for producing the mustard ethanol extract and peach blossom ethanol extract is as follows: Add 100 to 500 parts by weight of ethanol to 100 parts by weight of mustard leaf powder or peach blossom powder, and extract by stirring at 20 to 50 ° C. for 20 to 30 hours. Afterwards, it is prepared by filtration.
상기 치약 조성물은 천연 추출물 혼합물과 함께, 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 포함한다. 바람직하게는 치약 조성물 100중량% 중 천연 추출물 혼합물 1~5중량%, 덴탈 실리카 10~20중량%, 염화나트륨 0.1~1 중량%, 자일리톨 0.1~1 중량%, 자일리톨 0.1~1 중량%, 글리세린 5~10 중량%, 아스코르브산 0.01~1 중량%, 토코페롤아세테이트 0.01~1 중량%, 몰약틴크 0.01~0.1 중량%, 셀룰로오스검 1~3 중량%, 시트르산 0.1~0.5 중량%, 코코일글루타민산나트륨 5~10 중량%, 소르비톨액 40~60 중량%, 나머지 물을 포함한다.The toothpaste composition includes dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution and water, along with a mixture of natural extracts. Preferably, out of 100% by weight of the toothpaste composition, 1 to 5% by weight of natural extract mixture, 10 to 20% by weight of dental silica, 0.1 to 1% by weight of sodium chloride, 0.1 to 1% by weight of xylitol, 0.1 to 1% by weight of xylitol, and 5 to 5% of glycerin. 10% by weight, ascorbic acid 0.01~1% by weight, tocopherol acetate 0.01~1% by weight, myrrh tincture 0.01~0.1% by weight, cellulose gum 1~3% by weight, citric acid 0.1~0.5% by weight, sodium cocoyl glutamate 5~10 % by weight, including 40-60% by weight of sorbitol solution and the remaining water.
상기 치약 조성물은 치아미백제를 추가로 포할 수 있으며, 상기 치아미백제는 아염소산 금속, 과탄산염 및 과산화산으로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것일 수 있다. 상기 치약 미백제는 전체 치약 조성물 중 1~10중량%로 포함될 수 있다.The toothpaste composition may further contain a tooth whitening agent, and the tooth whitening agent may be composed of one or more selected from the group consisting of metal chlorite, percarbonate, and peroxy acid. The toothpaste whitening agent may be included in 1 to 10% by weight of the total toothpaste composition.
이하 본원을 실시예 및 실험예를 통하여 보다 상세하게 설명한다. 그러나 이들 실시예 및 시험예는 본 발명을 예시적으로 설명하기 위한 것으로 본원의 범위가 이들 실시예 및 시험예에 한정되는 것은 아니다.Hereinafter, the present application will be described in more detail through examples and experimental examples. However, these examples and test examples are for illustrative purposes only and the scope of the present application is not limited to these examples and test examples.
실시예 1Example 1
알로에 추출물 2중량%, 자몽 종자 추출물 2중량%, 녹차 추출물 2중량%, 금은화 추출물 3중량%, 강황 추출물 3중량%, 올리브 오일 3중량%, 감초 추출물 3중량%, 카렌듀라 추출물 4중량, 프로폴리스 추출물 2중량%, 세이지 추출물 3중량%, 황금 추출물 3중량%, 캐모마일 추출물 3중량%, 죽염 2중량%, 유칼립투스 오일 3중량%, L-멘톨 12중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조한다. 상기 천연 추출물 혼합물 5중량%, 덴탈 실리카 10중량%, 염화나트륨 0.5 중량%, 자일리톨 0.5 중량%, 자일리톨 0.2 중량%, 글리세린 5 중량%, 아스코르브산 0.01 중량%, 토코페롤아세테이트 0.01 중량%, 몰약틴크 0.05 중량%, 셀룰로오스검 2 중량%, 시트르산 0.2 중량%, 코코일글루타민산나트륨 5 중량%, 소르비톨액 50 중량%, 나머지 물을 포함하는 치약 조성물을 제조한다.Aloe extract 2% by weight, grapefruit seed extract 2% by weight, green tea extract 2% by weight, honeysuckle extract 3% by weight, turmeric extract 3% by weight, olive oil 3% by weight, licorice extract 3% by weight, calendura extract 4% by weight, pro Natural extracts including 2% by weight of police extract, 3% by weight of sage extract, 3% by weight of golden extract, 3% by weight of chamomile extract, 2% by weight of bamboo salt, 3% by weight of eucalyptus oil, 12% by weight of L-menthol and the remaining peppermint oil. Prepare the mixture. 5% by weight of the natural extract mixture, 10% by weight of dental silica, 0.5% by weight of sodium chloride, 0.5% by weight of xylitol, 0.2% by weight of xylitol, 5% by weight of glycerin, 0.01% by weight of ascorbic acid, 0.01% by weight of tocopherol acetate, 0.05% by weight of myrrh tincture. % by weight, 2% by weight of cellulose gum, 0.2% by weight of citric acid, 5% by weight of sodium cocoyl glutamate, 50% by weight of sorbitol solution, and the remaining water.
실시예 2Example 2
실시예 1에 있어서, 알로에 추출물 2중량%, 자몽 종자 추출물 2중량%, 녹차 추출물 2중량%, 금은화 추출물 3중량%, 강황 추출물 3중량%, 올리브 오일 3중량%, 감초 추출물 3중량%, 카렌듀라 추출물 4중량, 프로폴리스 추출물 2중량%, 세이지 추출물 3중량%, 황금 추출물 3중량%, 캐모마일 추출물 3중량%, 죽염 2중량%, 유칼립투스 오일 3중량%, L-멘톨 12중량%, 복숭아꽃 에탄올 추출물 4중량%, 갓 에탄올 추출물 4중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight aloe extract, 2% by weight grapefruit seed extract, 2% by weight green tea extract, 3% by weight honeysuckle extract, 3% by weight turmeric extract, 3% by weight olive oil, 3% by weight licorice extract, Karen. Dura extract 4% by weight, propolis extract 2% by weight, sage extract 3% by weight, golden extract 3% by weight, chamomile extract 3% by weight, bamboo salt 2% by weight, eucalyptus oil 3% by weight, L-menthol 12% by weight, peach blossom A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 4% by weight of ethanol extract, 4% by weight of fresh ethanol extract, and the remaining peppermint oil was prepared.
실시예 3Example 3
실시예 1에 있어서, 알로에 추출물 2중량%, 자몽 종자 추출물 2중량%, 녹차 추출물 2중량%, 금은화 추출물 3중량%, 강황 추출물 3중량%, 올리브 오일 3중량%, 감초 추출물 3중량%, 카렌듀라 추출물 4중량, 프로폴리스 추출물 2중량%, 세이지 추출물 3중량%, 황금 추출물 3중량%, 캐모마일 추출물 3중량%, 죽염 2중량%, 유칼립투스 오일 3중량%, L-멘톨 12중량%, 복숭아꽃 에탄올 추출물 8중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight aloe extract, 2% by weight grapefruit seed extract, 2% by weight green tea extract, 3% by weight honeysuckle extract, 3% by weight turmeric extract, 3% by weight olive oil, 3% by weight licorice extract, Karen. Dura extract 4% by weight, propolis extract 2% by weight, sage extract 3% by weight, golden extract 3% by weight, chamomile extract 3% by weight, bamboo salt 2% by weight, eucalyptus oil 3% by weight, L-menthol 12% by weight, peach blossom A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 8% by weight of ethanol extract and the remaining peppermint oil was prepared.
실시예 4Example 4
실시예 1에 있어서, 알로에 추출물 2중량%, 자몽 종자 추출물 2중량%, 녹차 추출물 2중량%, 금은화 추출물 3중량%, 강황 추출물 3중량%, 올리브 오일 3중량%, 감초 추출물 3중량%, 카렌듀라 추출물 4중량, 프로폴리스 추출물 2중량%, 세이지 추출물 3중량%, 황금 추출물 3중량%, 캐모마일 추출물 3중량%, 죽염 2중량%, 유칼립투스 오일 3중량%, L-멘톨 12중량%, 갓 에탄올 추출물 8중량% 및 나머지 페퍼민트 오일을 포함하는 천연 추출물 혼합물을 제조하는 것을 제외하고 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, 2% by weight aloe extract, 2% by weight grapefruit seed extract, 2% by weight green tea extract, 3% by weight honeysuckle extract, 3% by weight turmeric extract, 3% by weight olive oil, 3% by weight licorice extract, Karen. Dura extract 4% by weight, propolis extract 2% by weight, sage extract 3% by weight, golden extract 3% by weight, chamomile extract 3% by weight, bamboo salt 2% by weight, eucalyptus oil 3% by weight, L-menthol 12% by weight, fresh ethanol A toothpaste composition was prepared in the same manner as in Example 1, except that a natural extract mixture containing 8% by weight of extract and the remainder peppermint oil was prepared.
비교예 1Comparative Example 1
실시예 1에 있어서, 천연추출물 혼합물 대신에 항균제로 알려진 이소프로필메틸페놀, 사이클로헥시딘, 세틸피리디늄 클로라이드, 트키를로산으로 이루어진 항균제를 사용한 것을 제외하고, 실시예 1과 동일하게 치약 조성물을 제조한다.In Example 1, a toothpaste composition was prepared in the same manner as in Example 1, except that an antibacterial agent consisting of isopropylmethylphenol, cyclohexidine, cetylpyridinium chloride, and cyclohexane, known as antibacterial agents, was used instead of the natural extract mixture. manufactures.
실험예 1: 치주염 또는 치은염 개선 효과 확인Experimental Example 1: Confirmation of the effect of improving periodontitis or gingivitis
상기 실시예 및 비교예의 치약 조성물을 이용하여 치주염 또는 치은염 개선 효과를 확인하였다. 치주염 또는 치은염을 앓고 있는 환자 50명을 대상으로 상기 치약 조성물을 하루에 3번씩 3주동안 사용하게 하여, 잇몸의 개선 여부를 1점~10점으로 평가하여 확인하였다. The effect of improving periodontitis or gingivitis was confirmed using the toothpaste compositions of the above examples and comparative examples. Fifty patients suffering from periodontitis or gingivitis were asked to use the toothpaste composition three times a day for three weeks, and the improvement of their gums was evaluated on a scale of 1 to 10.
상기 표에 나타낸 바와 같이, 실시예 1 내지 4의 치약 조성물은 치주염 또는 치은염의 개선 효과가 있는 것을 확인하였으며, 특히 갓 추출물 및 복숭아꽃 추출물을 모두 포함하는 실시예 2의 치약 조성물의 치주염 또는 치은염 개선 효과가 우수한 것을 확인하였다.As shown in the table above, it was confirmed that the toothpaste compositions of Examples 1 to 4 had an effect of improving periodontitis or gingivitis. In particular, the toothpaste composition of Example 2 containing both mustard extract and peach blossom extract improved periodontitis or gingivitis. It was confirmed that the effect was excellent.
실험예 2: 세정도 및 사용감 평가Experimental Example 2: Evaluation of cleanliness and feeling of use
상기 실시예 및 비교예의 치약 조성물을 이용하여 세정도 및 사용감을 평가하였다. 20명의 성인에게 하루에 3번씩 3주동안 사용하게 하여, 세정도 및 사용감을 1점~10점으로 평가하여 확인하였다.The degree of cleansing and feeling of use were evaluated using the toothpaste compositions of the above Examples and Comparative Examples. Twenty adults were asked to use the product three times a day for three weeks, and the degree of cleansing and feeling of use were evaluated on a scale of 1 to 10.
상기 표에 나타낸 바와 같이, 실시예 1 내지 4의 치약 조성물은 세정도 및 사용감이 우수한 것을 확인하였으며, 특히 갓 추출물 및 복숭아꽃 추출물을 모두 포함하는 실시예 2의 치약 조성물의 세정도 및 사용감이 우수한 것을 확인하였다.As shown in the table above, it was confirmed that the toothpaste compositions of Examples 1 to 4 were excellent in cleanliness and feeling of use, and in particular, the toothpaste composition of Example 2 containing both mustard extract and peach blossom extract had excellent cleanliness and feeling of use. confirmed.
Claims (6)
상기 천연 추출물 혼합물은 천연 추출물 혼합물 100중량%에 대해 알로에 추출물 1~3중량%, 자몽 종자 추출물 1~3중량%, 녹차 추출물 1~3중량%, 금은화 추출물 2~4중량%, 강황 추출물 2~4중량%, 올리브 오일 2~4중량%, 감초 추출물 2~4중량%, 카렌듀라 추출물 3~5중량, 프로폴리스 추출물 1~3중량%, 세이지 추출물 2~4중량%, 황금 추출물 2~4중량%, 캐모마일 추출물 2~4중량%, 죽염 1~3중량%, 유칼립투스 오일 2~4중량%, 갓 추출물 3~5중량%, 복숭아꽃 추출물 3~5중량%, L-멘톨 10~15중량% 및 나머지 페퍼민트 오일을 포함하는 것을 포함하는 것인, 치은염 및 치주염 개선 또는 예방용 치약 조성물.Contains natural extract mixture, dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution and water.
The natural extract mixture contains 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, and 2-4% by weight of turmeric extract, based on 100% by weight of the natural extract mixture. 4% by weight, olive oil 2~4% by weight, licorice extract 2~4% by weight, calendura extract 3~5%, propolis extract 1~3% by weight, sage extract 2~4% by weight, golden extract 2~4 Weight %, chamomile extract 2~4% by weight, bamboo salt 1~3% by weight, eucalyptus oil 2~4% by weight, mustard leaf extract 3~5% by weight, peach blossom extract 3~5% by weight, L-menthol 10~15% by weight % and the remaining peppermint oil. A toothpaste composition for improving or preventing gingivitis and periodontitis.
상기 천연 추출물 혼합물과 덴탈 실리카, 염화나트륨, 자일리톨, 글리세린, 아스코르브산, 토코페롤아세테이트, 몰약틴크, 셀룰로오스검, 시트르산, 코코일글루타민산나트륨, 소르비톨액 및 물을 혼합하는 단계;를 포함하는, 치은염 및 치주염 개선 또는 예방용 치약 조성물의 제조 방법.Based on 100% by weight of natural extract mixture, 1-3% by weight of aloe extract, 1-3% by weight of grapefruit seed extract, 1-3% by weight of green tea extract, 2-4% by weight of honeysuckle extract, 2-4% by weight of turmeric extract, olive. Oil 2-4% by weight, licorice extract 2-4% by weight, calendura extract 3-5%, propolis extract 1-3% by weight, sage extract 2-4% by weight, golden extract 2-4% by weight, chamomile extract 2~4% by weight, bamboo salt 1~3% by weight, eucalyptus oil 2~4% by weight, mustard extract 3~5% by weight, peach blossom extract 3~5% by weight, L-menthol 10~15% by weight, and the remainder peppermint oil. Preparing a natural extract mixture by mixing;
Improving gingivitis and periodontitis, including mixing the natural extract mixture with dental silica, sodium chloride, xylitol, glycerin, ascorbic acid, tocopherol acetate, myrrh tincture, cellulose gum, citric acid, sodium cocoyl glutamate, sorbitol solution, and water. or a method for producing a preventive toothpaste composition.
복숭아꽃을 에탄올로 가열하여 추출하고, 여과하여 복숭아꽃 추출물을 제조하는 단계;
갓을 에탄올로 가열하여 추출하고, 여과하여 갓 추출물을 제조하는 단계;를 추가로 포함하는, 치은염 및 치주염 개선 또는 예방용 치약 조성물의 제조 방법.
According to clause 5,
Preparing peach flower extract by heating and extracting peach blossoms with ethanol and filtering them;
A method for producing a toothpaste composition for improving or preventing gingivitis and periodontitis, further comprising the step of extracting the mustard by heating it with ethanol and filtering it to prepare a mustard extract.
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