KR100400480B1 - 펩티드p277유사체들,그들을포함하는당뇨병의치료또는진단을위한약제학적조성물들및키트 - Google Patents

펩티드p277유사체들,그들을포함하는당뇨병의치료또는진단을위한약제학적조성물들및키트 Download PDF

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KR100400480B1
KR100400480B1 KR1019970704281A KR19970704281A KR100400480B1 KR 100400480 B1 KR100400480 B1 KR 100400480B1 KR 1019970704281 A KR1019970704281 A KR 1019970704281A KR 19970704281 A KR19970704281 A KR 19970704281A KR 100400480 B1 KR100400480 B1 KR 100400480B1
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peptide
cells
kit
iddm
val
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Korean (ko)
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이런 알. 코헨
다나 엘리아스
마티탸휴 프리드킨
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예다 리서치 앤드 디벨럽먼트 캄파니 리미티드
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Priority claimed from IL11209494A external-priority patent/IL112094A0/xx
Priority claimed from IL11446095A external-priority patent/IL114460A0/xx
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1019970704281A 1994-12-21 1995-12-20 펩티드p277유사체들,그들을포함하는당뇨병의치료또는진단을위한약제학적조성물들및키트 Expired - Lifetime KR100400480B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL112094 1994-12-21
IL11209494A IL112094A0 (en) 1994-12-21 1994-12-21 Novel peptides and pharmaceutical compositions comprising them
IL11446095A IL114460A0 (en) 1995-07-05 1995-07-05 Peptide p277 analogs and pharmaceutical compositions comprising them for treatment or diagnosis of diabetes
IL114460 1995-07-05

Publications (1)

Publication Number Publication Date
KR100400480B1 true KR100400480B1 (ko) 2003-12-31

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ID=26322965

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KR1019970704281A Expired - Lifetime KR100400480B1 (ko) 1994-12-21 1995-12-20 펩티드p277유사체들,그들을포함하는당뇨병의치료또는진단을위한약제학적조성물들및키트

Country Status (31)

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EP (1) EP0820303B1 (enExample)
JP (2) JP3420245B2 (enExample)
KR (1) KR100400480B1 (enExample)
CN (1) CN1233417C (enExample)
AR (1) AR002949A1 (enExample)
AT (1) ATE242005T1 (enExample)
AU (1) AU707835B2 (enExample)
BR (1) BR9510102A (enExample)
CA (1) CA2208274C (enExample)
CZ (1) CZ293784B6 (enExample)
DE (2) DE820303T1 (enExample)
DK (1) DK0820303T3 (enExample)
ES (1) ES2201137T3 (enExample)
FI (1) FI118373B (enExample)
HR (1) HRP950612B1 (enExample)
HU (1) HU224160B1 (enExample)
IL (1) IL116499A0 (enExample)
IS (1) IS1966B (enExample)
MX (1) MX9704738A (enExample)
NO (1) NO317350B1 (enExample)
NZ (1) NZ301440A (enExample)
PL (1) PL184145B1 (enExample)
PT (1) PT820303E (enExample)
RO (1) RO116777B1 (enExample)
RS (1) RS49517B (enExample)
SI (1) SI0820303T1 (enExample)
TR (1) TR199501630A2 (enExample)
TW (1) TW496872B (enExample)
UA (1) UA42040C2 (enExample)
UY (1) UY24130A1 (enExample)
WO (1) WO1996019236A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6488933B2 (en) 1995-07-05 2002-12-03 Yeda Research And Development Co. Ltd. Preparations for the treatment of T cell mediated diseases
JP3745380B2 (ja) * 1996-05-14 2006-02-15 ヴィンアッカー,エルンスト―ルートヴィッヒ プリオンタンパク質に結合し、イソ型PrP▲上c▼とPrP▲上sc▼を識別することが可能なシャペロン
CA2420499A1 (en) * 2000-08-25 2002-02-28 Yeda Research And Development Co. Ltd. Methods of treatment or prevention of autoimmune diseases with cpg-containing polynucleotide
IL140233A0 (en) * 2000-12-11 2002-02-10 Peptor Ltd Backbone cyclized analogs of heat shock proteins
WO2003063759A2 (en) 2002-01-31 2003-08-07 Peptor Ltd. Hsp peptides and analogs for modulation of immune responses via antigen presenting cells
WO2005072056A2 (en) * 2004-01-28 2005-08-11 Develogen Israel Ltd. Hsp therapy in conjunction with a low antigenicity diet
DE102004043750A1 (de) * 2004-09-10 2006-03-30 Sanofi-Aventis Deutschland Gmbh Formulierungen des Peptids p277 oder dessen Varianten mit optimierter Stabilität
RU2282453C2 (ru) * 2004-12-14 2006-08-27 Александр Борисович Смолянинов Способ терапии больных сахарным диабетом ii типа
CN100352502C (zh) * 2004-12-29 2007-12-05 中国药科大学 能通过免疫防治ⅰ型糖尿病的重组蛋白和重组基因
EP1835933A4 (en) * 2005-01-04 2015-01-07 Yeda Res & Dev HSP60, HSP60-PEPTIDES AND T-CELL VACCINES FOR IMMUNOMODULATION
WO2006096565A2 (en) * 2005-03-04 2006-09-14 Curedm Inc. Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions
EP2295066B1 (en) 2005-05-25 2016-04-27 CureDM Group Holdings, LLC Peptides, derivatives and analogs thereof, and methods of using same
JP4283812B2 (ja) * 2006-01-06 2009-06-24 財団法人工業技術研究院 重症筋無力症の診断方法およびそのキット
WO2008064306A2 (en) 2006-11-22 2008-05-29 Curedm, Inc. Methods and compositions relating to islet cell neogenesis
PT2193142E (pt) 2007-08-30 2015-04-22 Curedm Group Holdings Llc Composições e procedimentos de utilização de peptídeos pro-ilhota e seus análogos
CU23701A1 (es) * 2008-12-29 2011-09-21 Ct Ingenieria Genetica Biotech Método de tratamiento de enfermedades inflamatorias intestinales y diabetes tipo i
CN104244967A (zh) 2012-03-01 2014-12-24 耶达研究与发展有限公司 用于抑制和治疗非自身免疫性糖尿病的Hsp60衍生肽和肽类似物
WO2013128453A1 (en) 2012-03-01 2013-09-06 Yeda Research And Development Co. Ltd. Regeneration of islet beta cells by hsp60 derived peptides
CN104418948B (zh) * 2013-09-10 2019-08-16 深圳翰宇药业股份有限公司 一种制备多肽药物的方法
CN104650209B (zh) * 2013-11-19 2018-04-06 深圳翰宇药业股份有限公司 多肽药物DiaPep277 的合成方法
CN104650244B (zh) * 2015-01-21 2017-12-08 中国药科大学 一种具有降血糖兼调脂作用的表位组合肽及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
NO972849D0 (no) 1997-06-19
FI972669A0 (fi) 1997-06-19
HRP950612A2 (en) 1997-10-31
ATE242005T1 (de) 2003-06-15
WO1996019236A1 (en) 1996-06-27
CZ190897A3 (en) 1997-11-12
CZ293784B6 (cs) 2004-07-14
DK0820303T3 (da) 2003-10-06
TW496872B (en) 2002-08-01
IS4510A (is) 1997-06-19
EP0820303A1 (en) 1998-01-28
HUT78092A (hu) 1999-09-28
CN1233417C (zh) 2005-12-28
CN1175214A (zh) 1998-03-04
EP0820303B1 (en) 2003-06-04
BR9510102A (pt) 1997-11-25
HRP950612B1 (en) 2003-12-31
RO116777B1 (ro) 2001-06-29
JP3420245B2 (ja) 2003-06-23
SI0820303T1 (en) 2003-10-31
JP3554319B2 (ja) 2004-08-18
NO317350B1 (no) 2004-10-18
FI972669L (fi) 1997-08-15
JPH10511649A (ja) 1998-11-10
CA2208274A1 (en) 1996-06-27
AU707835B2 (en) 1999-07-22
MX9704738A (es) 1997-10-31
PL321091A1 (en) 1997-11-24
TR199501630A2 (tr) 1996-07-21
UY24130A1 (es) 1996-06-11
NZ301440A (en) 2000-01-28
IS1966B (is) 2004-12-15
ES2201137T3 (es) 2004-03-16
HU224160B1 (hu) 2005-06-28
PT820303E (pt) 2003-10-31
FI118373B (fi) 2007-10-31
AU4686696A (en) 1996-07-10
DE69531004D1 (de) 2003-07-10
DE820303T1 (de) 1999-05-20
PL184145B1 (pl) 2002-09-30
YU78795A (sh) 1998-05-15
DE69531004T2 (de) 2004-02-05
EP0820303A4 (enExample) 1998-03-11
NO972849L (no) 1997-08-13
RS49517B (sr) 2006-10-27
IL116499A0 (en) 1996-03-31
JP2004026797A (ja) 2004-01-29
AR002949A1 (es) 1998-05-27
UA42040C2 (uk) 2001-10-15
CA2208274C (en) 2005-12-06

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