RS49517B - PEPTID p277-ANALOZI I FARMACEUTSKI PREPARATI KOJI GA SADRZE - Google Patents

PEPTID p277-ANALOZI I FARMACEUTSKI PREPARATI KOJI GA SADRZE

Info

Publication number
RS49517B
RS49517B YU78795A YU78795A RS49517B RS 49517 B RS49517 B RS 49517B YU 78795 A YU78795 A YU 78795A YU 78795 A YU78795 A YU 78795A RS 49517 B RS49517 B RS 49517B
Authority
RS
Serbia
Prior art keywords
leu
gly
ala
peptide
analogs
Prior art date
Application number
YU78795A
Other languages
English (en)
Inventor
Irun R. Cohen
Dana Elias
Matityahu Fridkin
Original Assignee
Yeda Research And Development Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26322965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS49517(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL11209494A external-priority patent/IL112094A0/xx
Priority claimed from IL11446095A external-priority patent/IL114460A0/xx
Application filed by Yeda Research And Development Co. Ltd. filed Critical Yeda Research And Development Co. Ltd.
Publication of YU78795A publication Critical patent/YU78795A/sh
Publication of RS49517B publication Critical patent/RS49517B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Peptid sekvence I: 6 ; 11 Val-Leu-Gly-Gly-Gly-X1-Ala-Leu-Lwu-Arg-X2-Ile-Pro-19 ; (I) Ala-Leu-Asp-Ser-Leu-X3-Pro-Ala-Asn-Glu-Asp(SEQID br.2) gde X1 i X2 svaki posebno su Cys ili Val ostatak, a X3 je Thr ili Lys ostatak, a X1 i X2 ne mogu oba biti Cys ostaci kada X3 je Thr, kao i njihove soli i njihovi funkcionalni derivati. Prijava sadrži još 9 nezavisnih i 7 zavisnih patentnih zahteva.
YU78795A 1994-12-21 1995-12-21 PEPTID p277-ANALOZI I FARMACEUTSKI PREPARATI KOJI GA SADRZE RS49517B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11209494A IL112094A0 (en) 1994-12-21 1994-12-21 Novel peptides and pharmaceutical compositions comprising them
IL11446095A IL114460A0 (en) 1995-07-05 1995-07-05 Peptide p277 analogs and pharmaceutical compositions comprising them for treatment or diagnosis of diabetes

Publications (2)

Publication Number Publication Date
YU78795A YU78795A (sh) 1998-05-15
RS49517B true RS49517B (sr) 2006-10-27

Family

ID=26322965

Family Applications (1)

Application Number Title Priority Date Filing Date
YU78795A RS49517B (sr) 1994-12-21 1995-12-21 PEPTID p277-ANALOZI I FARMACEUTSKI PREPARATI KOJI GA SADRZE

Country Status (31)

Country Link
EP (1) EP0820303B1 (sr)
JP (2) JP3420245B2 (sr)
KR (1) KR100400480B1 (sr)
CN (1) CN1233417C (sr)
AR (1) AR002949A1 (sr)
AT (1) ATE242005T1 (sr)
AU (1) AU707835B2 (sr)
BR (1) BR9510102A (sr)
CA (1) CA2208274C (sr)
CZ (1) CZ293784B6 (sr)
DE (2) DE69531004T2 (sr)
DK (1) DK0820303T3 (sr)
ES (1) ES2201137T3 (sr)
FI (1) FI118373B (sr)
HR (1) HRP950612B1 (sr)
HU (1) HU224160B1 (sr)
IL (1) IL116499A0 (sr)
IS (1) IS1966B (sr)
MX (1) MX9704738A (sr)
NO (1) NO317350B1 (sr)
NZ (1) NZ301440A (sr)
PL (1) PL184145B1 (sr)
PT (1) PT820303E (sr)
RO (1) RO116777B1 (sr)
RS (1) RS49517B (sr)
SI (1) SI0820303T1 (sr)
TR (1) TR199501630A2 (sr)
TW (1) TW496872B (sr)
UA (1) UA42040C2 (sr)
UY (1) UY24130A1 (sr)
WO (1) WO1996019236A1 (sr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6488933B2 (en) 1995-07-05 2002-12-03 Yeda Research And Development Co. Ltd. Preparations for the treatment of T cell mediated diseases
WO1997043649A1 (en) * 1996-05-14 1997-11-20 Winnacker Ernst Ludwig CHARPERONES CAPABLE OF BINDING TO PRION PROTEINS AND DISTINGUISHING THE ISOFORMS PrPc AND PrP?sc¿
EP1335741A4 (en) * 2000-08-25 2005-10-26 Yeda Res & Dev METHOD FOR THE PREVENTION OF AUTOIMMUNE DISEASES WITH CpG-CONTAINING POLYNUCLEOTIDES (04.03.02)
IL140233A0 (en) * 2000-12-11 2002-02-10 Peptor Ltd Backbone cyclized analogs of heat shock proteins
EP1575479A4 (en) 2002-01-31 2006-10-25 Develogen Israel Ltd HSP-PEPTIDES AND ANALOGUES FOR MODULATING IMMUNE RESPONSES ON ANY PRESENTING CELLS
CA2595520A1 (en) 2004-01-28 2005-08-11 Develogen Israel Ltd. Hsp therapy in conjunction with a low antigenicity diet
DE102004043750A1 (de) * 2004-09-10 2006-03-30 Sanofi-Aventis Deutschland Gmbh Formulierungen des Peptids p277 oder dessen Varianten mit optimierter Stabilität
CN100352502C (zh) * 2004-12-29 2007-12-05 中国药科大学 能通过免疫防治ⅰ型糖尿病的重组蛋白和重组基因
EP1835933A4 (en) * 2005-01-04 2015-01-07 Yeda Res & Dev HSP60, PEPTIDES HSP60 AND T-CELL VACCINES FOR IMMUNOMODULATION
EP1858545A2 (en) 2005-03-04 2007-11-28 Curedm Inc. Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions
CA2726759C (en) 2005-05-25 2016-02-16 Curedm Group Holdings, Llc Human proislet peptide, derivatives and analogs thereof, and methods of using same
JP4283812B2 (ja) * 2006-01-06 2009-06-24 財団法人工業技術研究院 重症筋無力症の診断方法およびそのキット
WO2008064306A2 (en) 2006-11-22 2008-05-29 Curedm, Inc. Methods and compositions relating to islet cell neogenesis
EP2193142B1 (en) 2007-08-30 2015-01-07 CureDM Group Holdings, LLC Compositions and methods of using proislet peptides and analogs thereof
CU23701A1 (es) * 2008-12-29 2011-09-21 Ct Ingenieria Genetica Biotech Método de tratamiento de enfermedades inflamatorias intestinales y diabetes tipo i
CN104203263A (zh) 2012-03-01 2014-12-10 耶达研究与发展有限公司 利用HSP60衍生肽再生胰岛β细胞
JP2015508812A (ja) 2012-03-01 2015-03-23 イエダ リサーチ アンド ディベロプメント カンパニー リミテッド 非自己免疫性糖尿病を抑制および処置するためのｈｓｐ６０由来ペプチドおよびペプチド類似体
CN104418948B (zh) * 2013-09-10 2019-08-16 深圳翰宇药业股份有限公司 一种制备多肽药物的方法
CN104650209B (zh) * 2013-11-19 2018-04-06 深圳翰宇药业股份有限公司 多肽药物DiaPep277 的合成方法
CN104650244B (zh) * 2015-01-21 2017-12-08 中国药科大学 一种具有降血糖兼调脂作用的表位组合肽及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
FI972669A0 (fi) 1997-06-19
WO1996019236A1 (en) 1996-06-27
NO972849L (no) 1997-08-13
FI972669A (fi) 1997-08-15
IS1966B (is) 2004-12-15
CZ293784B6 (cs) 2004-07-14
HRP950612A2 (en) 1997-10-31
AR002949A1 (es) 1998-05-27
NZ301440A (en) 2000-01-28
CN1175214A (zh) 1998-03-04
JP3554319B2 (ja) 2004-08-18
TR199501630A2 (tr) 1996-07-21
JPH10511649A (ja) 1998-11-10
EP0820303A4 (sr) 1998-03-11
DE820303T1 (de) 1999-05-20
TW496872B (en) 2002-08-01
CA2208274C (en) 2005-12-06
ATE242005T1 (de) 2003-06-15
JP3420245B2 (ja) 2003-06-23
DE69531004T2 (de) 2004-02-05
AU4686696A (en) 1996-07-10
JP2004026797A (ja) 2004-01-29
HU224160B1 (hu) 2005-06-28
HRP950612B1 (en) 2003-12-31
MX9704738A (es) 1997-10-31
YU78795A (sh) 1998-05-15
EP0820303A1 (en) 1998-01-28
PL184145B1 (pl) 2002-09-30
CN1233417C (zh) 2005-12-28
AU707835B2 (en) 1999-07-22
DK0820303T3 (da) 2003-10-06
DE69531004D1 (de) 2003-07-10
RO116777B1 (ro) 2001-06-29
PT820303E (pt) 2003-10-31
IS4510A (is) 1997-06-19
PL321091A1 (en) 1997-11-24
BR9510102A (pt) 1997-11-25
SI0820303T1 (en) 2003-10-31
NO972849D0 (no) 1997-06-19
HUT78092A (hu) 1999-09-28
FI118373B (fi) 2007-10-31
UA42040C2 (uk) 2001-10-15
EP0820303B1 (en) 2003-06-04
NO317350B1 (no) 2004-10-18
CZ190897A3 (en) 1997-11-12
UY24130A1 (es) 1996-06-11
ES2201137T3 (es) 2004-03-16
KR100400480B1 (ko) 2003-12-31
CA2208274A1 (en) 1996-06-27
IL116499A0 (en) 1996-03-31

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