KR100286845B1 - 아미노-치환된 티오에테르의 제조방법 - Google Patents

아미노-치환된 티오에테르의 제조방법 Download PDF

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Publication number
KR100286845B1
KR100286845B1 KR1019940015725A KR19940015725A KR100286845B1 KR 100286845 B1 KR100286845 B1 KR 100286845B1 KR 1019940015725 A KR1019940015725 A KR 1019940015725A KR 19940015725 A KR19940015725 A KR 19940015725A KR 100286845 B1 KR100286845 B1 KR 100286845B1
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KR
South Korea
Prior art keywords
phenyl
methyl
formula
oxazolidinone
benzyl
Prior art date
Application number
KR1019940015725A
Other languages
English (en)
Korean (ko)
Other versions
KR950003267A (ko
Inventor
클라우스쿤데
칼-요제프헤르트
Original Assignee
빌프리더 하이더
바이엘 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19934322053 external-priority patent/DE4322053A1/de
Priority claimed from DE19934332978 external-priority patent/DE4332978A1/de
Application filed by 빌프리더 하이더, 바이엘 악티엔게젤샤프트 filed Critical 빌프리더 하이더
Publication of KR950003267A publication Critical patent/KR950003267A/ko
Application granted granted Critical
Publication of KR100286845B1 publication Critical patent/KR100286845B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/29—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019940015725A 1993-07-02 1994-07-01 아미노-치환된 티오에테르의 제조방법 KR100286845B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19934322053 DE4322053A1 (de) 1993-07-02 1993-07-02 Verfahren zur Herstellung von aminosubstituierten Thioethern
DEP4322053.3 1993-07-02
DE19934332978 DE4332978A1 (de) 1993-09-28 1993-09-28 Verfahren zur Herstellung von aminosubstituierten Thioethern
DEP4332978.0 1993-09-28

Publications (2)

Publication Number Publication Date
KR950003267A KR950003267A (ko) 1995-02-16
KR100286845B1 true KR100286845B1 (ko) 2001-04-16

Family

ID=25927329

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940015725A KR100286845B1 (ko) 1993-07-02 1994-07-01 아미노-치환된 티오에테르의 제조방법

Country Status (7)

Country Link
US (1) US5410081A (ja)
EP (1) EP0632022B1 (ja)
JP (1) JPH0717946A (ja)
KR (1) KR100286845B1 (ja)
CN (1) CN1038127C (ja)
DE (1) DE59401383D1 (ja)
TW (1) TW280812B (ja)

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* Cited by examiner, † Cited by third party
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EP0568876B1 (de) * 1992-05-04 1996-08-28 Bayer Ag Reaktivfarbstoffe, deren Herstellung und Verwendung
DE4441147A1 (de) * 1994-11-18 1996-05-23 Hoechst Ag Verfahren zur Herstellung von 3-(N-Aryl-amino)-propyl-2'-sulfatoethyl-sulfonyl-Verbindungen
CN1049623C (zh) * 1994-12-06 2000-02-23 叶元龙 聚乙烯类板材的熔接方法及其装置
WO1998004534A1 (fr) 1996-07-31 1998-02-05 Nikken Chemicals Co., Ltd. Derives de 6-phenyltetrahydro-1,3-oxazine-2-one et compositions medicinales a base de ces composes
AR057218A1 (es) * 2005-12-15 2007-11-21 Astra Ab Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato
JP5486928B2 (ja) * 2007-02-26 2014-05-07 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックウレアおよびカルバメートインヒビター
ES2395081T3 (es) * 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) * 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
WO2009102428A2 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1
CA2715290A1 (en) * 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5538356B2 (ja) * 2008-03-18 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134384A1 (en) * 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2393807B1 (en) 2009-02-04 2013-08-14 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
KR20120061771A (ko) * 2009-04-30 2012-06-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
EP2448928B1 (en) 2009-07-01 2014-08-13 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
EP2585444B1 (en) 2010-06-25 2014-10-22 Boehringer Ingelheim International GmbH Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
EA201300522A1 (ru) 2010-11-02 2013-11-29 Бёрингер Ингельхайм Интернациональ Гмбх Фармацевтические комбинации для лечения метаболических нарушений

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950542A (en) * 1967-02-21 1976-04-13 L'oreal Cysteamine derivatives for oral treatment of seborrhea
EP0498765A1 (de) * 1991-02-04 1992-08-12 Ciba-Geigy Ag Verfahren zur Herstellung von Alkyl- und Arylthiocarbonsäuren und deren Estern

Also Published As

Publication number Publication date
EP0632022A3 (en) 1995-02-01
EP0632022B1 (de) 1996-12-27
CN1038127C (zh) 1998-04-22
KR950003267A (ko) 1995-02-16
JPH0717946A (ja) 1995-01-20
US5410081A (en) 1995-04-25
DE59401383D1 (de) 1997-02-06
EP0632022A2 (de) 1995-01-04
TW280812B (ja) 1996-07-11
CN1097739A (zh) 1995-01-25

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