US7550561B1
(en)
|
1991-05-16 |
2009-06-23 |
Cold Spring Harbor Laboratory |
p16INK4 polypeptides
|
US5889169A
(en)
*
|
1991-05-16 |
1999-03-30 |
Cold Spring Harbor Laboratory |
Cell cycle regulatory protein p16 gene
|
US5981273A
(en)
*
|
1991-09-30 |
1999-11-09 |
Boehringer Ingelheim Int'l. Gmbh |
Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
|
NZ244306A
(en)
|
1991-09-30 |
1995-07-26 |
Boehringer Ingelheim Int |
Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
|
US5521291A
(en)
*
|
1991-09-30 |
1996-05-28 |
Boehringer Ingelheim International, Gmbh |
Conjugates for introducing nucleic acid into higher eucaryotic cells
|
US6627615B1
(en)
|
1991-12-17 |
2003-09-30 |
The Regents Of The University Of California |
Methods and compositions for in vivo gene therapy
|
US5756353A
(en)
*
|
1991-12-17 |
1998-05-26 |
The Regents Of The University Of California |
Expression of cloned genes in the lung by aerosol-and liposome-based delivery
|
US5858784A
(en)
*
|
1991-12-17 |
1999-01-12 |
The Regents Of The University Of California |
Expression of cloned genes in the lung by aerosol- and liposome-based delivery
|
US5922859A
(en)
*
|
1992-02-01 |
1999-07-13 |
Boehringer Ingelheim International Gmbh |
Complexes containing nucleic acid which can be taken-up by endocytosis into higher eukaryotic cells
|
US6806084B1
(en)
|
1992-06-04 |
2004-10-19 |
The Regents Of The University Of California |
Methods for compositions for in vivo gene delivery
|
IL105914A0
(en)
*
|
1992-06-04 |
1993-10-20 |
Univ California |
Methods and compositions for in vivo gene therapy
|
US5962316A
(en)
|
1992-10-16 |
1999-10-05 |
Cold Spring Harbor Laboratory |
Cell-cycle regulatory proteins, and uses related thereto
|
US6211334B1
(en)
|
1992-10-16 |
2001-04-03 |
Cold Spring Harbor |
Cell-cycle regulatory proteins, and uses related thereto
|
EP0674705A4
(en)
*
|
1992-11-09 |
1997-11-26 |
Univ Jefferson |
ANTISENSE OLIGONUCLEOTIDES USED TO INHIBIT THE EXPRESSION OF MUTATED AND WILD-LIKE COLLAGEN GENES.
|
US5574142A
(en)
*
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
US6331390B1
(en)
|
1992-12-17 |
2001-12-18 |
Cold Spring Harbor Laboratory |
Cell-cycle regulatory proteins, and uses related thereto
|
US6043030A
(en)
*
|
1992-12-17 |
2000-03-28 |
Cold Spring Harbor Laboratory |
Cell-cycle regulatory proteins, and uses related thereto
|
WO1994016736A1
(en)
*
|
1993-01-22 |
1994-08-04 |
University Research Corporation |
Localization of therapeutic agents
|
CA2159916A1
(en)
*
|
1993-04-05 |
1994-10-13 |
Henry C. Chiou |
Targeted delivery of genes encoding antisense polyribonucleotides
|
EP0693939A1
(de)
*
|
1993-04-14 |
1996-01-31 |
Roche Diagnostics GmbH |
Nukleinsäure-transferpeptide und deren verwendung zur einschleusung von nukleinsäuren in eukaryontische zellen
|
GB9317380D0
(en)
*
|
1993-08-20 |
1993-10-06 |
Therexsys Ltd |
Transfection process
|
DE4331012A1
(de)
*
|
1993-09-13 |
1995-03-16 |
Bayer Ag |
Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
|
DE4331011A1
(de)
*
|
1993-09-13 |
1995-03-16 |
Bayer Ag |
Nukleinsäuren-bindende Oligomere mit C-Verzweigung für Therapie und Diagnostik
|
US7691632B2
(en)
|
1993-11-18 |
2010-04-06 |
Cold Spring Harbor Laboratory |
Kit for detecting the level of cyclin-dependent kinase inhibitor P16 gene expression
|
US5728518A
(en)
*
|
1994-01-12 |
1998-03-17 |
The Immune Response Corporation |
Antiviral poly-and oligonucleotides
|
AU1925195A
(en)
|
1994-02-22 |
1995-09-04 |
Dana-Farber Cancer Institute |
Nucleic acid delivery system, method of synthesis and uses thereof
|
AU2589695A
(en)
*
|
1994-05-13 |
1995-12-05 |
Chiron Corporation |
Compositions and methods for targeting gene delivery vehicles
|
FR2721612B1
(fr)
*
|
1994-06-23 |
1996-08-09 |
Idm |
Nouveaux dérivés d'oligosides, leur procédé de préparation et leurs applications.
|
US5728399A
(en)
*
|
1994-06-29 |
1998-03-17 |
University Of Conn. |
Use of a bacterial component to enhance targeted delivery of polynucleotides to cells
|
DE4427980A1
(de)
*
|
1994-08-08 |
1996-02-15 |
Bayer Ag |
Nukleinsäuren-bindende Oligomere für Therapie und Diagnostik
|
AU4690596A
(en)
*
|
1994-12-30 |
1996-07-24 |
Chiron Viagene, Inc. |
Nucleic acid condensing agents with reduced immunogenicity
|
AU5259796A
(en)
|
1995-02-10 |
1996-08-27 |
Worcester Foundation For Biomedical Research, Inc. |
Delivery of exogenous compounds
|
WO1996030386A1
(fr)
*
|
1995-03-31 |
1996-10-03 |
Drug Delivery System Institute, Ltd. |
Derives d'amidite et derives d'oligonucleotides
|
US5856459A
(en)
*
|
1995-06-06 |
1999-01-05 |
Hybridon, Inc. |
Oligonucleotides specific for hepatitis B virus
|
ATE466948T1
(de)
|
1997-03-11 |
2010-05-15 |
Univ Minnesota |
Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
|
US6524613B1
(en)
|
1997-04-30 |
2003-02-25 |
Regents Of The University Of Minnesota |
Hepatocellular chimeraplasty
|
CA2291074C
(en)
|
1997-05-21 |
2008-04-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Composition and method for enhancing transport across biological membranes
|
WO1998055611A1
(en)
*
|
1997-06-06 |
1998-12-10 |
Regents Of The University Of Michigan |
Neuregulin response element and uses therefor
|
US6635623B1
(en)
*
|
1997-06-13 |
2003-10-21 |
Baylor College Of Medicine |
Lipoproteins as nucleic acid vectors
|
EP1019511A2
(en)
|
1997-10-01 |
2000-07-19 |
Dana-Farber Cancer Institute |
STABILIZATION OF ENVELOPE GLYCOPROTEIN TRIMERS BY DISULFIDE BONDS INTRODUCED INTO A gp41 GLYCOPROTEIN ECTODOMAIN
|
EP1053355B1
(en)
*
|
1998-02-11 |
2001-11-14 |
PE Corporation (NY) |
Pna and dna conjugates and methods for preparation thereof
|
US6210892B1
(en)
*
|
1998-10-07 |
2001-04-03 |
Isis Pharmaceuticals, Inc. |
Alteration of cellular behavior by antisense modulation of mRNA processing
|
US7160682B2
(en)
|
1998-11-13 |
2007-01-09 |
Regents Of The University Of Minnesota |
Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
|
DE19858005B4
(de)
*
|
1998-12-16 |
2007-02-08 |
november Aktiengesellschaft, Gesellschaft für Molekulare Medizin |
Synthetisches Nucleinsäure-Partikel
|
EP1210121A2
(en)
|
1999-08-24 |
2002-06-05 |
Cellgate Inc. |
Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties
|
US7229961B2
(en)
|
1999-08-24 |
2007-06-12 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into ocular tissues
|
US6669951B2
(en)
|
1999-08-24 |
2003-12-30 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
US6271360B1
(en)
|
1999-08-27 |
2001-08-07 |
Valigen (Us), Inc. |
Single-stranded oligodeoxynucleotide mutational vectors
|
DE69923840T2
(de)
*
|
1999-09-09 |
2006-04-06 |
Curevac Gmbh |
Transfer von mRNAs unter Verwendung von polykationischen Verbindungen
|
JP2004509604A
(ja)
*
|
2000-03-28 |
2004-04-02 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
mRNAプロセッシングのアンチセンスモジュレーションによる、細胞行動の改変
|
EP1286699A2
(en)
*
|
2000-05-19 |
2003-03-05 |
Regents Of The University Of Minnesota |
Composition for delivery of compounds to cells
|
EP1478751A4
(en)
|
2001-03-30 |
2005-10-19 |
Avigenics Inc |
LYSOZYM PROMOTER IN BIRDS
|
US7176300B2
(en)
|
2001-03-30 |
2007-02-13 |
Avigenics, Inc. |
Avian lysozyme promoter
|
US7541512B2
(en)
|
2001-03-30 |
2009-06-02 |
Synageva Biopharma Corp. |
Avians containing a lysozyme promoter transgene
|
US7550650B2
(en)
|
2001-09-18 |
2009-06-23 |
Synageva Biopharma Corp. |
Production of a transgenic avian by cytoplasmic injection
|
US7335761B2
(en)
|
2001-11-30 |
2008-02-26 |
Avigenics, Inc. |
Avian gene expression controlling regions
|
US6875588B2
(en)
|
2001-11-30 |
2005-04-05 |
Avigenics, Inc. |
Ovomucoid promoter and methods of use
|
US7294507B2
(en)
|
2001-11-30 |
2007-11-13 |
Avigenics, Inc. |
Ovomucoid promoters and methods of use
|
US7135562B2
(en)
|
2002-03-14 |
2006-11-14 |
University Of Cincinnati |
Avian iFABP gene expression controlling region
|
AU2003231048A1
(en)
|
2002-04-22 |
2003-11-03 |
Regents Of The University Of Minnesota |
Transposon system and methods of use
|
CN100369930C
(zh)
|
2002-11-26 |
2008-02-20 |
Pdl生物制药股份有限公司 |
调节血管生成的α5β1整合素的嵌合的和人源化的抗体
|
US7312320B2
(en)
|
2003-12-10 |
2007-12-25 |
Novimmune Sa |
Neutralizing antibodies and methods of use thereof
|
EP1697399B1
(en)
|
2003-12-12 |
2016-11-23 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS |
A human cytotoxic t-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of muc-1
|
NL1027479C2
(nl)
*
|
2004-10-21 |
2006-05-01 |
Synvolux Ip B V |
Bescherming van biologisch actieve moleculen met behulp van amphifielen.
|
AU2006208084B2
(en)
|
2005-01-25 |
2012-07-26 |
Prolexys Pharmaceuticals, Inc. |
Quinoxaline Derivatives as Antitumor Agents
|
WO2007109583A2
(en)
|
2006-03-17 |
2007-09-27 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject
|
EP2111553B1
(en)
|
2007-01-24 |
2018-09-19 |
Carnegie Mellon University |
Optical biosensors
|
EP2222701B1
(en)
|
2007-12-06 |
2017-11-01 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against influenza virus and methods of use thereof
|
WO2010096388A2
(en)
|
2009-02-18 |
2010-08-26 |
Carnegie Mellon University |
Quenched dendrimeric dyes for bright detection
|
PE20120815A1
(es)
|
2009-05-05 |
2012-07-08 |
Novimmune Sa |
Anticuerpos anti il-17f y metodos de uso de los mismos
|
US20130079382A1
(en)
|
2009-10-12 |
2013-03-28 |
Larry J. Smith |
Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro
|
CN108404123A
(zh)
|
2010-01-15 |
2018-08-17 |
康奈尔大学 |
降低细胞内蛋白质水平的方法
|
CA2787628A1
(en)
|
2010-01-21 |
2011-07-28 |
Dana-Farber Cancer Institute, Inc. |
Context specific genetic screen platform to aid in gene discovery and target validation
|
US9995679B2
(en)
|
2010-05-25 |
2018-06-12 |
Carnegie Mellon University |
Targeted probes of cellular physiology
|
CA2800531C
(en)
|
2010-06-02 |
2021-05-25 |
Dana-Farber Cancer Institute, Inc. |
Humanized monoclonal antibodies and methods of use
|
WO2012092299A1
(en)
|
2010-12-27 |
2012-07-05 |
Brown University |
Therapeutic and diagnostic methods involving biglycan and utrophin
|
HUE037613T2
(hu)
|
2012-03-29 |
2018-09-28 |
Novimmune Sa |
Anti-TLR4 antitestek és azok felhasználása
|
AU2013256010B2
(en)
|
2012-05-04 |
2018-01-04 |
Dana-Farber Cancer Institute, Inc. |
Affinity matured anti-CCR4 humanized monoclonal antibodies and methods of use
|
CA3139031A1
(en)
|
2012-10-04 |
2014-04-10 |
Dana-Farber Cancer Institute, Inc. |
Human monoclonal anti-pd-l1 antibodies and methods of use
|
CA2892585C
(en)
|
2012-12-03 |
2022-07-05 |
Novimmune S.A. |
Anti-cd47 antibodies and methods of use thereof
|
WO2015143194A2
(en)
|
2014-03-19 |
2015-09-24 |
Dana-Farber Cancer Institute, Inc. |
Immunogenetic restriction on elicitation of antibodies
|
EP4112070A1
(en)
|
2014-04-25 |
2023-01-04 |
Dana Farber Cancer Institute, Inc. |
Middle east respiratory syndrome coronavirus neutralizing antibodies and methods of use thereof
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
RU2017115315A
(ru)
|
2014-10-03 |
2018-11-08 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Антитела к рецептору глюкокортикоид-индуцированного фактора некроза опухоли (gitr) и способы их применения
|
WO2016057488A1
(en)
|
2014-10-06 |
2016-04-14 |
Dana-Farber Cancer Institute, Inc. |
Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof
|
US10434177B2
(en)
|
2014-11-17 |
2019-10-08 |
Carnegie Mellon University |
Activatable two-component photosensitizers
|
CN107406503B
(zh)
|
2014-11-18 |
2021-07-16 |
詹森药业有限公司 |
Cd47抗体、方法和用途
|
EP3411713B1
(en)
|
2016-02-05 |
2021-06-30 |
NanoView Biosciences, Inc. |
Detection of exosomes having surface markers
|
EP4302782A3
(en)
|
2016-03-15 |
2024-03-27 |
Mersana Therapeutics, Inc. |
Napi2b-targeted antibody-drug conjugates and methods of use thereof
|
RU2019104896A
(ru)
|
2016-07-22 |
2020-08-24 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Антитела к глюкокортикоид-индуцированному рецептору фактора некроза опухоли (gitr) и способы их использования
|
CA3035081A1
(en)
|
2016-09-02 |
2018-03-08 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating b cell disorders
|
US20190233505A1
(en)
|
2016-09-06 |
2019-08-01 |
Dana-Farber Cancer Institute, Inc. |
Methods of treating or preventing zika virus infection
|
TW201825674A
(zh)
|
2016-09-09 |
2018-07-16 |
美商艾斯合顧問有限公司 |
表現雙特異性接合分子的溶瘤病毒
|
CA3093330A1
(en)
|
2018-03-14 |
2019-09-19 |
Novimmune Sa |
Anti-cd3 epsilon antibodies and methods of use thereof
|