KR0168649B1 - 비스(3,5-디-알킬-4-히드록시페닐티오)메탄을 유효 성분으로 함유하는 고트리글리세리드혈증 치료용 제약 조성물 - Google Patents

비스(3,5-디-알킬-4-히드록시페닐티오)메탄을 유효 성분으로 함유하는 고트리글리세리드혈증 치료용 제약 조성물 Download PDF

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Publication number
KR0168649B1
KR0168649B1 KR1019910010091A KR910010091A KR0168649B1 KR 0168649 B1 KR0168649 B1 KR 0168649B1 KR 1019910010091 A KR1019910010091 A KR 1019910010091A KR 910010091 A KR910010091 A KR 910010091A KR 0168649 B1 KR0168649 B1 KR 0168649B1
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KR
South Korea
Prior art keywords
hypertriglyceridemia
methane
hydroxyphenylthio
pharmaceutical composition
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019910010091A
Other languages
English (en)
Korean (ko)
Other versions
KR920000327A (ko
Inventor
젠 탄 마오 사이몬
쿠 죠지
리 잭슨 리챠드
Original Assignee
게리 디. 스트리트
메렐 다우 파마슈티칼스 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 게리 디. 스트리트, 메렐 다우 파마슈티칼스 인크. filed Critical 게리 디. 스트리트
Publication of KR920000327A publication Critical patent/KR920000327A/ko
Application granted granted Critical
Publication of KR0168649B1 publication Critical patent/KR0168649B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019910010091A 1990-06-19 1991-06-18 비스(3,5-디-알킬-4-히드록시페닐티오)메탄을 유효 성분으로 함유하는 고트리글리세리드혈증 치료용 제약 조성물 Expired - Fee Related KR0168649B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US540,657 1990-06-19
US07/540,657 US5122542A (en) 1990-06-19 1990-06-19 Hypotriglyceridemic use of certain bis (3,5-di-alkyl-4-hydroxyphenylthio)methanes

Publications (2)

Publication Number Publication Date
KR920000327A KR920000327A (ko) 1992-01-29
KR0168649B1 true KR0168649B1 (ko) 1999-01-15

Family

ID=24156398

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910010091A Expired - Fee Related KR0168649B1 (ko) 1990-06-19 1991-06-18 비스(3,5-디-알킬-4-히드록시페닐티오)메탄을 유효 성분으로 함유하는 고트리글리세리드혈증 치료용 제약 조성물

Country Status (13)

Country Link
US (1) US5122542A (OSRAM)
EP (1) EP0462556B1 (OSRAM)
JP (1) JPH04230213A (OSRAM)
KR (1) KR0168649B1 (OSRAM)
AT (1) ATE129151T1 (OSRAM)
AU (1) AU640486B2 (OSRAM)
DE (1) DE69113871T2 (OSRAM)
DK (1) DK0462556T3 (OSRAM)
ES (1) ES2080854T3 (OSRAM)
GR (1) GR3018351T3 (OSRAM)
IE (1) IE69315B1 (OSRAM)
TW (1) TW205542B (OSRAM)
ZA (1) ZA914538B (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063408A1 (en) * 2004-12-17 2006-06-22 Stocker Ronald O Compositions and methods for treating cardiovascular disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734527A (en) * 1986-10-17 1988-03-29 Merrell Dow Pharmaceuticals Inc. Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol
US4954528A (en) * 1988-12-08 1990-09-04 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic use of bis(3,5-di-tertiary-butly-4-hydroxyphenylthio)methane
US4900757A (en) * 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
US4959392A (en) * 1989-07-24 1990-09-25 Merrell Dow Pharmaceuticals Inc. Method of treating diabetes mellitus

Also Published As

Publication number Publication date
DE69113871D1 (de) 1995-11-23
DK0462556T3 (da) 1995-11-27
AU7836591A (en) 1992-01-02
JPH04230213A (ja) 1992-08-19
IE912087A1 (en) 1992-01-01
EP0462556A2 (en) 1991-12-27
TW205542B (OSRAM) 1993-05-11
EP0462556A3 (en) 1992-03-11
ATE129151T1 (de) 1995-11-15
AU640486B2 (en) 1993-08-26
KR920000327A (ko) 1992-01-29
IE69315B1 (en) 1996-09-04
ZA914538B (en) 1992-03-25
ES2080854T3 (es) 1996-02-16
GR3018351T3 (en) 1996-03-31
EP0462556B1 (en) 1995-10-18
US5122542A (en) 1992-06-16
DE69113871T2 (de) 1996-04-04

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