KE3207A - Hexahydroazepine,piperidine and pyrrolidine derivatives - Google Patents

Hexahydroazepine,piperidine and pyrrolidine derivatives

Info

Publication number
KE3207A
KE3207A KE3207A KE320782A KE3207A KE 3207 A KE3207 A KE 3207A KE 3207 A KE3207 A KE 3207A KE 320782 A KE320782 A KE 320782A KE 3207 A KE3207 A KE 3207A
Authority
KE
Kenya
Prior art keywords
hexahydroazepine
piperidine
pyrrolidine derivatives
pyrrolidine
derivatives
Prior art date
Application number
KE3207A
Other languages
English (en)
Inventor
John Frederick Cavalla
Alan Chapman White
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of KE3207A publication Critical patent/KE3207A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
KE3207A 1977-12-22 1982-04-06 Hexahydroazepine,piperidine and pyrrolidine derivatives KE3207A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53370/77A GB1593888A (en) 1977-12-22 1977-12-22 Hexahydroazepine piperidine and pyrrolidine derivatives

Publications (1)

Publication Number Publication Date
KE3207A true KE3207A (en) 1982-05-21

Family

ID=10467561

Family Applications (2)

Application Number Title Priority Date Filing Date
KE3206A KE3206A (en) 1977-12-22 1982-04-06 Hexahydroazepine,piperidine and pyrrolidine derivatives
KE3207A KE3207A (en) 1977-12-22 1982-04-06 Hexahydroazepine,piperidine and pyrrolidine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KE3206A KE3206A (en) 1977-12-22 1982-04-06 Hexahydroazepine,piperidine and pyrrolidine derivatives

Country Status (33)

Country Link
US (2) US4197241A (xx)
EP (1) EP0003253B1 (xx)
JP (1) JPS5488286A (xx)
AR (1) AR221710A1 (xx)
AT (1) AT373586B (xx)
AU (1) AU519653B2 (xx)
CA (2) CA1113092A (xx)
CS (1) CS207748B2 (xx)
CY (2) CY1144A (xx)
DD (2) DD149515A5 (xx)
DE (1) DE2862139D1 (xx)
DK (1) DK156302C (xx)
EG (1) EG13745A (xx)
ES (2) ES476160A1 (xx)
FI (1) FI70575C (xx)
GB (1) GB1593888A (xx)
GR (1) GR64029B (xx)
HK (2) HK18082A (xx)
HU (1) HU181997B (xx)
IE (1) IE47631B1 (xx)
IL (1) IL55924A (xx)
IN (1) IN150193B (xx)
IT (1) IT1102761B (xx)
KE (2) KE3206A (xx)
MX (1) MX5628E (xx)
MY (2) MY8200279A (xx)
NZ (1) NZ188863A (xx)
PH (2) PH14517A (xx)
PL (1) PL126008B1 (xx)
PT (1) PT68962A (xx)
SU (1) SU1301311A3 (xx)
YU (1) YU40543B (xx)
ZA (1) ZA786244B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021772B1 (en) * 1979-07-03 1985-01-02 JOHN WYETH & BROTHER LIMITED Method of preparing 2-oxo- and 2-unsubstituted-hexahydroazepine derivatives
IE54154B1 (en) * 1981-12-02 1989-07-05 Wyeth John & Brother Ltd M-hydroxyphenyl substituted compounds
US5665754A (en) * 1993-09-20 1997-09-09 Glaxo Wellcome Inc. Substituted pyrrolidines
SE0001438D0 (sv) 2000-04-18 2000-04-18 Axon Chemicals Bv New chemical compounds and their use in therapy
KR100421282B1 (ko) * 2001-08-22 2004-03-09 부광약품 주식회사 1-메틸헥사히드로-4-아제피논 염산염의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2524643A (en) * 1947-12-04 1950-10-03 Maltbie Lab Inc 3-phenyl-2-piperidones
US3149123A (en) * 1961-01-04 1964-09-15 Parke Davis & Co 1, 3-dialkyl-3-oxyphenylpyrrolidine compounds
NL265485A (xx) * 1961-06-02
FR1337793A (fr) * 1962-06-19 1963-09-20 Parke Davis & Co Composés de pyrrolidine et procédé de préparation de ces composés
GB1285025A (en) * 1968-08-16 1972-08-09 Wyeth John & Brother Ltd Hexahydroazepines
CH526534A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate
CH526535A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate
CH526536A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer 3-Phenylpyrrolidinderivate
US3729465A (en) * 1971-02-03 1973-04-24 Wyeth John & Brother Ltd Hexahydroazepines
JPS4911844A (xx) * 1972-05-09 1974-02-01
BE850777A (fr) * 1976-01-28 1977-07-26 Sandoz Sa Nouveaux derives de la pyrrolidine

Also Published As

Publication number Publication date
EG13745A (en) 1983-03-31
DE2862139D1 (en) 1983-01-27
AT373586B (de) 1984-02-10
AR221710A1 (es) 1981-03-13
PT68962A (en) 1979-01-01
CY1145A (en) 1982-09-10
MY8200279A (en) 1982-12-31
ES481125A1 (es) 1980-02-01
CA1113092A (en) 1981-11-24
FI70575B (fi) 1986-06-06
EP0003253B1 (en) 1982-12-22
PH14412A (en) 1981-07-09
CA1113465A (en) 1981-12-01
DK546578A (da) 1979-06-23
IT7831286A0 (it) 1978-12-22
YU40543B (en) 1986-02-28
MY8200278A (en) 1982-12-31
US4197241A (en) 1980-04-08
PL126008B1 (en) 1983-06-30
GR64029B (en) 1980-01-19
CS207748B2 (en) 1981-08-31
IL55924A (en) 1982-01-31
KE3206A (en) 1982-05-21
HU181997B (en) 1983-11-28
IE782252L (en) 1979-06-22
EP0003253A1 (en) 1979-08-08
PL211970A1 (xx) 1980-02-25
GB1593888A (en) 1981-07-22
IL55924A0 (en) 1979-01-31
PH14517A (en) 1981-08-26
MX5628E (es) 1983-11-15
US4197239A (en) 1980-04-08
IT1102761B (it) 1985-10-07
DK156302B (da) 1989-07-31
AU4147978A (en) 1979-06-28
YU299778A (en) 1983-12-31
ZA786244B (en) 1980-06-25
CY1144A (en) 1982-09-10
IN150193B (xx) 1982-08-14
HK18082A (en) 1982-05-07
FI783922A (fi) 1979-06-23
ATA898578A (de) 1983-06-15
NZ188863A (en) 1982-03-16
JPS5488286A (en) 1979-07-13
DK156302C (da) 1989-12-11
AU519653B2 (en) 1981-12-17
IE47631B1 (en) 1984-05-16
JPS64392B2 (xx) 1989-01-06
ES476160A1 (es) 1979-11-16
HK18182A (en) 1982-05-07
SU1301311A3 (ru) 1987-03-30
FI70575C (fi) 1986-09-24
DD141308A5 (de) 1980-04-23
DD149515A5 (de) 1981-07-15

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