IT7831286A0 - Derivati della esaidroazepina, piperidina e pirrolidina. - Google Patents
Derivati della esaidroazepina, piperidina e pirrolidina.Info
- Publication number
- IT7831286A0 IT7831286A0 IT7831286A IT3128678A IT7831286A0 IT 7831286 A0 IT7831286 A0 IT 7831286A0 IT 7831286 A IT7831286 A IT 7831286A IT 3128678 A IT3128678 A IT 3128678A IT 7831286 A0 IT7831286 A0 IT 7831286A0
- Authority
- IT
- Italy
- Prior art keywords
- hexhydroazepine
- pyrrolidine
- piperidine
- derivatives
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 3
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
- ZSIQJIWKELUFRJ-UHFFFAOYSA-N azepane Chemical class C1CCCNCC1 ZSIQJIWKELUFRJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB53370/77A GB1593888A (en) | 1977-12-22 | 1977-12-22 | Hexahydroazepine piperidine and pyrrolidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7831286A0 true IT7831286A0 (it) | 1978-12-22 |
| IT1102761B IT1102761B (it) | 1985-10-07 |
Family
ID=10467561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT31286/78A IT1102761B (it) | 1977-12-22 | 1978-12-22 | Derivati della esaidroazepina, piperidina e pirrolidina |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US4197239A (it) |
| EP (1) | EP0003253B1 (it) |
| JP (1) | JPS5488286A (it) |
| AR (1) | AR221710A1 (it) |
| AT (1) | AT373586B (it) |
| AU (1) | AU519653B2 (it) |
| CA (2) | CA1113465A (it) |
| CS (1) | CS207748B2 (it) |
| CY (2) | CY1145A (it) |
| DD (2) | DD141308A5 (it) |
| DE (1) | DE2862139D1 (it) |
| DK (1) | DK156302C (it) |
| EG (1) | EG13745A (it) |
| ES (2) | ES476160A1 (it) |
| FI (1) | FI70575C (it) |
| GB (1) | GB1593888A (it) |
| GR (1) | GR64029B (it) |
| HK (2) | HK18082A (it) |
| HU (1) | HU181997B (it) |
| IE (1) | IE47631B1 (it) |
| IL (1) | IL55924A (it) |
| IN (1) | IN150193B (it) |
| IT (1) | IT1102761B (it) |
| KE (2) | KE3206A (it) |
| MX (1) | MX5628E (it) |
| MY (2) | MY8200279A (it) |
| NZ (1) | NZ188863A (it) |
| PH (2) | PH14412A (it) |
| PL (1) | PL126008B1 (it) |
| PT (1) | PT68962A (it) |
| SU (1) | SU1301311A3 (it) |
| YU (1) | YU40543B (it) |
| ZA (1) | ZA786244B (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3069897D1 (en) * | 1979-07-03 | 1985-02-14 | Wyeth John & Brother Ltd | Method of preparing 2-oxo- and 2-unsubstituted-hexahydroazepine derivatives |
| IE54154B1 (en) * | 1981-12-02 | 1989-07-05 | Wyeth John & Brother Ltd | M-hydroxyphenyl substituted compounds |
| US5665754A (en) * | 1993-09-20 | 1997-09-09 | Glaxo Wellcome Inc. | Substituted pyrrolidines |
| SE0001438D0 (sv) | 2000-04-18 | 2000-04-18 | Axon Chemicals Bv | New chemical compounds and their use in therapy |
| KR100421282B1 (ko) * | 2001-08-22 | 2004-03-09 | 부광약품 주식회사 | 1-메틸헥사히드로-4-아제피논 염산염의 제조방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2524643A (en) * | 1947-12-04 | 1950-10-03 | Maltbie Lab Inc | 3-phenyl-2-piperidones |
| US3149123A (en) * | 1961-01-04 | 1964-09-15 | Parke Davis & Co | 1, 3-dialkyl-3-oxyphenylpyrrolidine compounds |
| NL265485A (it) * | 1961-06-02 | |||
| FR1337793A (fr) * | 1962-06-19 | 1963-09-20 | Parke Davis & Co | Composés de pyrrolidine et procédé de préparation de ces composés |
| GB1285025A (en) * | 1968-08-16 | 1972-08-09 | Wyeth John & Brother Ltd | Hexahydroazepines |
| CH526535A (de) * | 1970-02-05 | 1972-08-15 | Sandoz Ag | Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate |
| CH526536A (de) * | 1970-02-05 | 1972-08-15 | Sandoz Ag | Verfahren zur Herstellung neuer 3-Phenylpyrrolidinderivate |
| CH526534A (de) * | 1970-02-05 | 1972-08-15 | Sandoz Ag | Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate |
| US3729465A (en) * | 1971-02-03 | 1973-04-24 | Wyeth John & Brother Ltd | Hexahydroazepines |
| JPS4911844A (it) * | 1972-05-09 | 1974-02-01 | ||
| BE850777A (fr) * | 1976-01-28 | 1977-07-26 | Sandoz Sa | Nouveaux derives de la pyrrolidine |
-
1977
- 1977-12-22 GB GB53370/77A patent/GB1593888A/en not_active Expired
-
1978
- 1978-05-30 CY CY1145A patent/CY1145A/xx unknown
- 1978-05-30 CY CY1144A patent/CY1144A/xx unknown
- 1978-11-06 ZA ZA786244A patent/ZA786244B/xx unknown
- 1978-11-08 NZ NZ188863A patent/NZ188863A/xx unknown
- 1978-11-09 CA CA316,048A patent/CA1113465A/en not_active Expired
- 1978-11-09 CA CA316,049A patent/CA1113092A/en not_active Expired
- 1978-11-10 AU AU41479/78A patent/AU519653B2/en not_active Expired
- 1978-11-10 IL IL55924A patent/IL55924A/xx unknown
- 1978-11-15 US US05/961,086 patent/US4197239A/en not_active Expired - Lifetime
- 1978-11-15 IE IE2252/78A patent/IE47631B1/en unknown
- 1978-11-15 US US05/961,087 patent/US4197241A/en not_active Expired - Lifetime
- 1978-11-20 IN IN1249/CAL/78A patent/IN150193B/en unknown
- 1978-11-28 AR AR274561A patent/AR221710A1/es active
- 1978-11-30 MX MX787562U patent/MX5628E/es unknown
- 1978-11-30 DK DK546578A patent/DK156302C/da not_active IP Right Cessation
- 1978-12-06 EP EP78300753A patent/EP0003253B1/en not_active Expired
- 1978-12-06 DE DE7878300753T patent/DE2862139D1/de not_active Expired
- 1978-12-08 PH PH21913A patent/PH14412A/en unknown
- 1978-12-08 PH PH21914A patent/PH14517A/en unknown
- 1978-12-15 AT AT0898578A patent/AT373586B/de not_active IP Right Cessation
- 1978-12-19 GR GR57927A patent/GR64029B/el unknown
- 1978-12-19 YU YU2997/78A patent/YU40543B/xx unknown
- 1978-12-20 PL PL1978211970A patent/PL126008B1/pl unknown
- 1978-12-20 ES ES476160A patent/ES476160A1/es not_active Expired
- 1978-12-20 DD DD78209990A patent/DD141308A5/de unknown
- 1978-12-20 DD DD78219713A patent/DD149515A5/de unknown
- 1978-12-20 SU SU782699100A patent/SU1301311A3/ru active
- 1978-12-20 FI FI783922A patent/FI70575C/fi not_active IP Right Cessation
- 1978-12-20 EG EG724/78A patent/EG13745A/xx active
- 1978-12-21 HU HU78WI298A patent/HU181997B/hu unknown
- 1978-12-21 CS CS788756A patent/CS207748B2/cs unknown
- 1978-12-21 PT PT68962A patent/PT68962A/pt unknown
- 1978-12-21 JP JP15695778A patent/JPS5488286A/ja active Granted
- 1978-12-22 IT IT31286/78A patent/IT1102761B/it active
-
1979
- 1979-05-31 ES ES481125A patent/ES481125A1/es not_active Expired
-
1982
- 1982-04-06 KE KE3206A patent/KE3206A/xx unknown
- 1982-04-06 KE KE3207A patent/KE3207A/xx unknown
- 1982-04-29 HK HK180/82A patent/HK18082A/xx not_active IP Right Cessation
- 1982-04-29 HK HK181/82A patent/HK18182A/xx not_active IP Right Cessation
- 1982-12-30 MY MY279/82A patent/MY8200279A/xx unknown
- 1982-12-30 MY MY278/82A patent/MY8200278A/xx unknown
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