JPWO2023002011A5 - - Google Patents
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- Publication number
- JPWO2023002011A5 JPWO2023002011A5 JP2024503904A JP2024503904A JPWO2023002011A5 JP WO2023002011 A5 JPWO2023002011 A5 JP WO2023002011A5 JP 2024503904 A JP2024503904 A JP 2024503904A JP 2024503904 A JP2024503904 A JP 2024503904A JP WO2023002011 A5 JPWO2023002011 A5 JP WO2023002011A5
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- piperazin
- quinolyl
- dihydrochloride
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21306032.0 | 2021-07-23 | ||
| EP21306032 | 2021-07-23 | ||
| PCT/EP2022/070601 WO2023002011A1 (en) | 2021-07-23 | 2022-07-22 | Gram-negative bacteria efflux pump inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024527427A JP2024527427A (ja) | 2024-07-24 |
| JP2024527427A5 JP2024527427A5 (https=) | 2025-07-11 |
| JPWO2023002011A5 true JPWO2023002011A5 (https=) | 2025-07-11 |
Family
ID=77564041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024503904A Pending JP2024527427A (ja) | 2021-07-23 | 2022-07-22 | グラム陰性細菌排出ポンプ阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240327354A1 (https=) |
| EP (1) | EP4373808A1 (https=) |
| JP (1) | JP2024527427A (https=) |
| KR (1) | KR20240057402A (https=) |
| CN (1) | CN118076585A (https=) |
| WO (1) | WO2023002011A1 (https=) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0200024B1 (de) * | 1985-04-30 | 1992-07-01 | ARZNEIMITTELWERK DRESDEN GmbH | 3-Cyan-pyridine, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| AU2001280091A1 (en) * | 2000-08-01 | 2002-02-13 | Wockhardt Limited | Inhibitors of cellular efflux pumps of microbes |
| US7074794B2 (en) * | 2000-08-10 | 2006-07-11 | Mitsubishi Pharma Corporation | Proline derivatives and the use thereof as drugs |
| JP2007507514A (ja) * | 2003-09-30 | 2007-03-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | キノキサリン化合物 |
| EP1836189A1 (en) * | 2005-01-06 | 2007-09-26 | AstraZeneca AB | Novel pyridine compounds |
| EP1987827A1 (en) * | 2006-02-20 | 2008-11-05 | Takeda Pharmaceutical Company Limited | Novel pharmaceutical |
| TW200815426A (en) * | 2006-06-28 | 2008-04-01 | Astrazeneca Ab | New pyridine analogues II 333 |
| MX2009000577A (es) * | 2006-07-14 | 2009-03-09 | Schering Corp | Compuestos de piperazina sustituida heterociclica con actividad antagonista de cxcr3. |
| TW201204727A (en) * | 2010-03-10 | 2012-02-01 | Kalypsys Inc | Heterocyclic inhibitors of histamine receptors for the treatment of disease |
| JP2011246461A (ja) * | 2010-04-27 | 2011-12-08 | Mitsubishi Tanabe Pharma Corp | 新規アミド誘導体を含有する医薬組成物 |
| EA201390476A1 (ru) * | 2010-09-28 | 2013-08-30 | Бристол-Майерс Сквибб Компани | Новые пиперазиновые аналоги с замещенными гетероарильными группами в качестве противовирусных средств широкого применения против гриппа |
| EP3371164B1 (en) * | 2015-11-06 | 2022-03-16 | Neurocrine Biosciences, Inc. | N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(pyrazin-2-yl)-piperazine-1-carboxamide derivatives and related compounds as muscarinic receptor 4 (m4) antagonists for treating neurological diseases |
| WO2017097927A1 (en) * | 2015-12-11 | 2017-06-15 | Syngenta Participations Ag | Pesticidally active 1,2,4-triazole derivatives |
| US20190119236A1 (en) * | 2016-02-23 | 2019-04-25 | Portola Pharmaceuticals, Inc. | Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9) |
| WO2017160069A1 (ko) * | 2016-03-15 | 2017-09-21 | 재단법인 의약바이오컨버젼스연구단 | 신규한 벤젠설폰아미드 유도체 및 이의 용도 |
| MX393606B (es) * | 2016-12-30 | 2025-03-19 | Mitobridge Inc | Inhibidores de poli-adp ribosa polimerasa (parp) |
| US11518764B2 (en) * | 2018-02-06 | 2022-12-06 | Ontario Institute For Cancer Research (Oicr) | Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interaction |
| JP7637328B2 (ja) * | 2019-02-07 | 2025-02-28 | ベイジーン リミテッド | Ｔｌｒ７アゴニストとしてのイミダゾ［２，１－ｆ］［１，２，４］トリアジン－４－アミン誘導体 |
| WO2021067859A1 (en) * | 2019-10-03 | 2021-04-08 | Tenaya Therapeutics, Inc. | 5-fluoronicotinamide derivatives and uses thereof |
| WO2021127333A1 (en) * | 2019-12-19 | 2021-06-24 | Casma Therapeutics, Inc. | Trpml modulators |
-
2022
- 2022-07-22 CN CN202280059217.2A patent/CN118076585A/zh active Pending
- 2022-07-22 WO PCT/EP2022/070601 patent/WO2023002011A1/en not_active Ceased
- 2022-07-22 US US18/579,953 patent/US20240327354A1/en active Pending
- 2022-07-22 KR KR1020247005022A patent/KR20240057402A/ko active Pending
- 2022-07-22 JP JP2024503904A patent/JP2024527427A/ja active Pending
- 2022-07-22 EP EP22757228.6A patent/EP4373808A1/en active Pending
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